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Jul 2026
www.nature.com www.nature.com

Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse

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1. scibot 22 Jul 2026
  
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  Addgene, 105536
  
  DOI: 10.1038/s41587-026-03184-3
  
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nature.com/articles/s41587-026-03184-3
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sleep regulates hepatic neutrophil trafficking by modulating uric acid metabolism via sympathetic nervous system activity

1
1. scibot 10 Jun 2026
  
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  addgene_105536
  
  DOI: 10.64898/2026.04.28.721287
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13142481/
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sex- and hepatocyte PPARγ-dependent effects of an obesogenic dietary approach to induce MASH with fibrosis in mice

1
1. scibot 08 Apr 2026
  
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  105536
  
  DOI: 10.64898/2026.02.25.707976
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13015395/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The functionally conserved human lncRNA motif GULF lowers glucose and lipid levels in obese mice

1
1. scibot 23 Nov 2025
  
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  105536
  
  DOI: 10.1172/JCI186355
  
  Resource: RRID:Addgene_105536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12435843/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Diploid Hepatocytes Resist Acetaminophen-Induced Liver Injury Through Suppressed JNK Signaling

1
1. scibot 08 Aug 2025
  
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  105536
  
  DOI: 10.1101/2025.07.31.667940
  
  Resource: RRID:Addgene_105536
  
  Curator: @dhovakimyan1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324546/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of hepatic autophagy induces α‐cell proliferation through impaired glutamine‐dependent gluconeogenesis

1
1. scibot 15 Jun 2025
  
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  Addgene_105536
  
  DOI: 10.14814/phy2.70381
  
  Resource: RRID:Addgene_105536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12106947/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3

1
1. scibot 16 May 2025
  
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  105536
  
  DOI: 10.1038/s41586-025-08677-w
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12003176/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Disrupting bile acid metabolism by suppressing Fxr causes hepatocellular carcinoma induced by YAP activation

1
1. scibot 16 May 2025
  
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  105536
  
  DOI: 10.1038/s41467-025-58809-z
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12000370/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Human-correlated genetic models identify precision therapy for liver cancer

1
1. scibot 23 Mar 2025
  
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  105536
  
  DOI: 10.1038/s41586-025-08585-z
  
  Resource: RRID:Addgene_105536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11922762/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Use of an oversized AAV8 vector for CPS1 deficiency results in long-term survival and ammonia control

1
1. scibot 18 Mar 2025
  
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  plasmid_105536
  
  DOI: 10.1016/j.omtn.2025.102470
  
  Resource: RRID:Addgene_105536
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11905892/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury

1
1. scibot 11 Mar 2025
  
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  pAAV.TBG.PI.Null.bGH
  
  DOI: 10.1097/HC9.0000000000000636
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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  DOI:10.1097/HC9.0000000000000636 RRID:Addgene_105536
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RRID:Addgene_105536

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pmc.ncbi.nlm.nih.gov/articles/PMC11781774/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension

1
1. scibot 16 Jan 2025
  
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  Addgene_105536
  
  DOI: 10.1038/s41598-024-84515-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11696687/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NCLX controls hepatic mitochondrial Ca2+ extrusion and couples hormone-mediated mitochondrial Ca2+ oscillations with gluconeogenesis

1
1. scibot 26 Aug 2024
  
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  105536
  
  DOI: 10.1016/j.molmet.2024.101982
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11325370/
Jun 2024
www.biorxiv.org www.biorxiv.org

Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension

1
1. scibot 22 Jun 2024
  
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  Addgene_105536
  
  DOI: 10.1101/2024.06.06.597821
  
  Resource: RRID:Addgene_105536
  
  Curator: @scibot
  
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biorxiv.org/content/10.1101/2024.06.06.597821v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice

1
1. scibot 15 Jun 2024
  
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  105536
  
  DOI: 10.1038/s41467-024-49332-8
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11169405/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system

1
1. scibot 30 Apr 2024
  
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  Addgene_105536
  
  DOI: 10.21203/rs.3.rs-4196140/v1
  
  Resource: RRID:Addgene_105536
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030518/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Modifications of the GH Axis Reveal Unique Sexually Dimorphic Liver Signatures for Lcn13, Asns, Hamp2, Hao2, and Pgc1a

1
1. scibot 21 Feb 2024
  
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  AAV8-TBGp-Null
  
  DOI: 10.1210/jendso/bvae015
  
  Resource: RRID:Addgene_105536
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_105536
  
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  RRID:Addgene_105536
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ncbi.nlm.nih.gov/pmc/articles/PMC10872697/
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise

1
1. scibot 23 Feb 2023
  
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  RRID:Addgene_105536
  
  DOI: 10.1016/j.cmet.2023.01.011
  
  Resource: RRID:Addgene_105536
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413123000116
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

2
1. scibot 07 Apr 2022
  
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  Addgene105536
  
  DOI: 10.1016/j.cmet.2022.03.005
  
  Resource: RRID:Addgene_105536
  
  Curator: @sophiastull
  
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  RRID:Addgene_105536
2. scibot 07 Apr 2022
  
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  RRID:Addgene_105536
  
  DOI: 10.1016/j.cmet.2022.03.005
  
  Resource: RRID:Addgene_105536
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_105536
  
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sciencedirect.com/science/article/pii/S1550413122000936
Jan 2022
www.nature.com www.nature.com

RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state

1
1. scibot 22 Jan 2022
  
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  RRID:Addgene_105536
  
  DOI: 10.1038/s41467-021-27923-z
  
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nature.com/articles/s41467-021-27923-z
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

1
1. scibot 30 Apr 2021
  
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  Addgene_105536
  
  DOI: 10.1016/j.ccell.2021.03.012
  
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sciencedirect.com/science/article/pii/S1535610821001707