Hypothesis

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Dec 2025
www.biorxiv.org www.biorxiv.org

A clinical-stage oncology compound selectively targets drug-resistant cancers

1
1. scibot 06 Dec 2025
  
  in Public
  
  Addgene_108099
  
  DOI: 10.1101/2025.11.26.690878
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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RRID:Addgene_108099

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scibot

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biorxiv.org/content/10.1101/2025.11.26.690878v1
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

1
1. scibot 06 Sep 2025
  
  in Public
  
  Addgene_108099
  
  DOI: 10.1101/2024.11.17.624023
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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RRID:Addgene_108099

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12393259/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

1
1. scibot 24 Dec 2024
  
  in Public
  
  RRID:Addgene_108099
  
  DOI: 10.1016/j.molcel.2024.11.040
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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RRID:Addgene_108099

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scibot

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sciencedirect.com/science/article/pii/S109727652400995X
Dec 2023
www.sciencedirect.com www.sciencedirect.com

B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling

1
1. scibot 17 Dec 2023
  
  in Public
  
  RRID:Addgene_108099
  
  DOI: 10.1016/j.ccell.2023.11.008
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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scibot

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sciencedirect.com/science/article/pii/S1535610823003999
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia

1
1. scibot 08 Oct 2022
  
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  Addgene:108099
  
  DOI: 10.1016/j.isci.2022.105139
  
  Resource: RRID:Addgene_108099
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC9526175/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

1
1. scibot 25 Jun 2022
  
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  Addgene_108099
  
  DOI: 10.1016/j.molcel.2022.06.005
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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RRID:Addgene_108099

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scibot

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sciencedirect.com/science/article/pii/S109727652200541X
Feb 2022
www.sciencedirect.com www.sciencedirect.com

EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells

1
1. scibot 23 Feb 2022
  
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  Addgene Cat# 108099
  
  DOI: 10.1016/j.molcel.2022.01.015
  
  Resource: RRID:Addgene_108099
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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sciencedirect.com/science/article/pii/S1097276522000582
Aug 2021
www.sciencedirect.com www.sciencedirect.com

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
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  Addgene:108099
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: RRID:Addgene_108099
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099 RRIDCUR:Missing
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RRID:Addgene_108099

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521005876
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques

1
1. scibot 28 Jul 2021
  
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  LRCherry2.1
  
  DOI: 10.1016/j.molcel.2019.01.006
  
  Resource: RRID:Addgene_108099
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099 RRIDCUR:Missing
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RRID:Addgene_108099

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276519300061
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

1
1. scibot 02 Mar 2021
  
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  RRID:Addgene_108099
  
  DOI: 10.7554/eLife.65905
  
  Resource: RRID:Addgene_108099
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108099
  
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  RRID:Addgene_108099
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
Jan 2020
www.nature.com www.nature.com

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_108099
  
  DOI: 10.1038/s41467-019-13086-5
  
  Resource: RRID:Addgene_108099
  
  Curator: @evieth
  
  SciCrunch record: Addgene_108099
  
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  RRID:Addgene_108099 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_108099

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scibot

URL

nature.com/articles/s41467-019-13086-5