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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Multimodal control of Cas13d activity through domain insertion at an allosteric hotspot

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1. scibot 08 Aug 2026
  
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  109050
  
  DOI: 10.1038/s41467-026-73645-5
  
  Resource: RRID:Addgene_109050
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13396516/
Jul 2026
www.sciencedirect.com www.sciencedirect.com

Disruption of microhomology-mediated end joining in Ewing sarcoma

1
1. scibot 23 Jul 2026
  
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  plasmid_109050
  
  DOI: 10.1016/j.molcel.2026.06.038
  
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sciencedirect.com/science/article/pii/S109727652600451X
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Splicing factor TRA2B enhances synthesis of androgen receptor variant AR-V7 in prostate cancer cells

1
1. scibot 08 Apr 2026
  
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  109050
  
  DOI: 10.1172/JCI198264
  
  Resource: RRID:Addgene_109050
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13038199/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations

1
1. scibot 23 Nov 2025
  
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  plasmid_109050
  
  DOI: 10.1101/2025.03.21.644128
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11974705/
Aug 2025
www.cell.com www.cell.com

Systematic screening for functional exon-skipping isoforms using the CRISPR-RfxCas13d system

1
1. scibot 08 Aug 2025
  
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  Addgene_109050
  
  DOI: 10.1016/j.cels.2025.101351
  
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cell.com/cell-systems/fulltext/S2405-4712(25)00184-X
Jun 2025
www.nature.com www.nature.com

Programmable control of spatial transcriptome in live cells and neurons

1
1. scibot 24 Jun 2025
  
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  109050
  
  DOI: 10.1038/s41586-025-09020-z
  
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nature.com/articles/s41586-025-09020-z
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Generative modeling for RNA splicing predictions and design

1
1. scibot 11 Mar 2025
  
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  109050
  
  DOI: 10.1101/2025.01.20.633986
  
  Resource: RRID:Addgene_109050
  
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  RRID:Addgene_109050 DOI:10.1101/2025.01.20.633986
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DOI:10.1101/2025.01.20.633986

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pmc.ncbi.nlm.nih.gov/articles/PMC11785043/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-molecule live-cell RNA imaging with CRISPR-Csm

1
1. scibot 18 Aug 2024
  
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  plasmid_109050
  
  DOI: 10.1101/2024.07.14.603457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11275710/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25

1
1. scibot 24 Jul 2024
  
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  Addgene_109050
  
  DOI: 10.1016/j.molcel.2024.05.028
  
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sciencedirect.com/science/article/pii/S1097276524004751
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tunable translation-level CRISPR interference by dCas13 and engineered gRNA in bacteria

1
1. scibot 30 Jun 2024
  
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  Addgene_109050
  
  DOI: 10.1038/s41467-024-49642-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11193725/
May 2024
www.sciencedirect.com www.sciencedirect.com

Lineage-specific splicing regulation of MAPT gene in the primate brain

2
1. scibot 21 May 2024
  
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  Addgene52109050
  
  DOI: 10.1016/j.xgen.2024.100563
  
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  Curator: @abever99
  
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2. scibot 21 May 2024
  
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  plasmid_109050
  
  DOI: 10.1016/j.xgen.2024.100563
  
  Resource: RRID:Addgene_109050
  
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sciencedirect.com/science/article/pii/S2666979X24001290
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-dCas13d-based deep screening of proximal and distal splicing-regulatory elements

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1. scibot 12 May 2024
  
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  Addgene_109050
  
  DOI: 10.1038/s41467-024-47140-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11076525/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase

1
1. scibot 23 Apr 2024
  
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  109050
  
  DOI: 10.1093/nar/gkae110
  
  Resource: RRID:Addgene_109050
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11014266/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Engineering a synthetic gene circuit for high-performance inducible expression in mammalian systems

1
1. scibot 23 Apr 2024
  
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  pXR002
  
  DOI: 10.1038/s41467-024-47592-y
  
  Resource: RRID:Addgene_109050
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11024104/
Mar 2024
www.nature.com www.nature.com

dCas13-mediated translational repression for accurate gene silencing in mammalian cells

1
1. scibot 14 Mar 2024
  
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  RRID:Addgene_109050
  
  DOI: 10.1038/s41467-024-46412-7
  
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nature.com/articles/s41467-024-46412-7
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Noncoding function of super enhancer derived mRNA in modulating neighboring gene expression and TAD interaction

1
1. scibot 28 Dec 2023
  
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  RRID:Addgene_109050
  
  DOI: 10.1101/2023.12.05.570115
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10723268/
www.sciencedirect.com www.sciencedirect.com

Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors

1
1. scibot 17 Dec 2023
  
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  Addgene_109050
  
  DOI: 10.1016/j.molcel.2023.10.034
  
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sciencedirect.com/science/article/pii/S1097276523008717
May 2023
www.biorxiv.org www.biorxiv.org

CRISPRδ: dCas13-mediated translational repression for accurate gene silencing in mammalian cells

1
1. scibot 19 May 2023
  
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  RRID:Addgene_109050
  
  DOI: 10.1101/2023.05.14.540671
  
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  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_109050
  
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biorxiv.org/content/10.1101/2023.05.14.540671v1
Dec 2022
journals.plos.org journals.plos.org

A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells

1
1. scibot 05 Dec 2022
  
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  RRID:Addgene_109050
  
  DOI: 10.1371/journal.pbio.3001885
  
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journals.plos.org/plosbiology/article
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells

1
1. scibot 17 Aug 2022
  
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  Addgene_109050
  
  DOI: 10.1016/j.celrep.2022.111226
  
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sciencedirect.com/science/article/pii/S2211124722010439
Mar 2022
www.sciencedirect.com www.sciencedirect.com

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex

1
1. scibot 30 Mar 2022
  
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  RRID:Addgene_109050
  
  DOI: 10.1016/j.celrep.2022.110421
  
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sciencedirect.com/science/article/pii/S2211124722001450