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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Thioredoxin Reductase 1 inhibition triggers ferroptosis in KRAS-independent lung cancers

1
1. scibot 11 Aug 2025
  
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  111177
  
  DOI: 10.1101/2025.07.25.666783
  
  Resource: RRID:Addgene_111177
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324224/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability

1
1. scibot 20 Jul 2025
  
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  111177
  
  DOI: 10.1158/0008-5472.CAN-24-2471
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11735329/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration

1
1. scibot 10 Jul 2025
  
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  Addgene_111177
  
  DOI: 10.1002/ijc.35490
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development

1
1. scibot 18 Jun 2025
  
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  RRID:Addgene_111177
  
  DOI: 10.1158/0008-5472.CAN-24-4576
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
www.sciencedirect.com www.sciencedirect.com

Cohesin supercoils DNA during loop extrusion

1
1. scibot 14 Jun 2025
  
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  RRID:Addgene_111177
  
  DOI: 10.1016/j.celrep.2025.115856
  
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sciencedirect.com/science/article/pii/S2211124725006278
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 04 Apr 2025
  
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  RRID:Addgene_111177
  
  DOI: 10.1158/0008-5472.can-24-4576
  
  Resource: RRID:Addgene_111177
  
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52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer

1
1. scibot 04 Apr 2025
  
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  RRID:Addgene_111177
  
  DOI: 10.1038/s44318-025-00381-9
  
  Resource: RRID:Addgene_111177
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11962125/
Mar 2025
www.nature.com www.nature.com

Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation

1
1. scibot 11 Mar 2025
  
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  111177
  
  DOI: 10.1038/s42255-024-01201-w
  
  Resource: RRID:Addgene_111177
  
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  DOI:10.1038/s42255-024-01201-w RRID:Addgene_111177
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DOI:10.1038/s42255-024-01201-w

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nature.com/articles/s42255-024-01201-w
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer

1
1. scibot 27 Sep 2024
  
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  LT3-GEPIR
  
  DOI: 10.1038/s42255-024-01118-4
  
  Resource: RRID:Addgene_111177
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11422168/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2

1
1. scibot 29 Aug 2024
  
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  Addgene: 111177
  
  DOI: 10.1136/gutjnl-2023-331519
  
  Resource: RRID:Addgene_111177
  
  Curator: @vtello
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II

1
1. scibot 26 Aug 2024
  
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  111177
  
  DOI: 10.7554/eLife.94407
  
  Resource: RRID:Addgene_111177
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate

1
1. scibot 26 Aug 2024
  
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  Addgene_111177
  
  DOI: 10.1101/2024.07.08.602542
  
  Resource: RRID:Addgene_111177
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11257442/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing

1
1. scibot 13 Aug 2024
  
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  111177
  
  DOI: 10.1186/s13045-024-01572-3
  
  Resource: RRID:Addgene_111177
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11290012/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer

3
1. scibot 31 Jul 2024
  
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  111177
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
  Resource: Addgene_111177
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_111177
  
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  RRID:Addgene_111177
2. scibot 31 Jul 2024
  
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  Addgene_111177
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
  Resource: Addgene_111177
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111177
  
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  RRID:Addgene_111177
3. scibot 31 Jul 2024
  
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  Addgene_111177
  
  DOI: 10.1158/2159-8290.CD-23-0539
  
  Resource: Addgene_111177
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111177
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability

1
1. scibot 30 Apr 2024
  
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  plasmid_111177
  
  DOI: 10.1101/2024.04.11.589139
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11042198/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium

1
1. scibot 29 Feb 2024
  
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  LT3GEPIR
  
  DOI: 10.1038/s42003-024-05817-2
  
  Resource: RRID:Addgene_111177
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_111177
  
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  RRID:Addgene_111177
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ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
www.sciencedirect.com www.sciencedirect.com

Specialized replication mechanisms maintain genome stability at human centromeres

2
1. scibot 15 Feb 2024
  
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  Addgene_111177
  
  DOI: 10.1016/j.molcel.2024.01.018
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111177
  
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  RRID:Addgene_111177
2. scibot 15 Feb 2024
  
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  Addgene_111177
  
  DOI: 10.1016/j.molcel.2024.01.018
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111177
  
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sciencedirect.com/science/article/pii/S1097276524000546
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms

1
1. scibot 17 Aug 2023
  
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  RRID:Addgene_111177
  
  DOI: 10.1016/j.molcel.2023.07.024
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276523005671
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones

1
1. scibot 02 Jun 2023
  
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  Addgene_111177
  
  DOI: 10.1016/j.cell.2023.05.003
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0092867423005226
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Asparagine starvation suppresses histone demethylation through iron depletion

1
1. scibot 09 Apr 2023
  
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  RRID:Addgene_111177
  
  DOI: 10.1016/j.isci.2023.106425
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
www.nature.com www.nature.com

RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status

1
1. scibot 06 Apr 2023
  
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  RRID:Addgene_111177
  
  DOI: 10.1038/s41388-023-02683-w
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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nature.com/articles/s41388-023-02683-w
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma

1
1. scibot 12 Jan 2023
  
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  RRID:Addgene_111177
  
  DOI: 10.1158/0008-5472.CAN-22-0959
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9755964/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry

1
1. scibot 07 Jan 2023
  
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  RRID:Addgene_111177
  
  DOI: 10.1158/2159-8290.CD-21-1671
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
Aug 2022
52.53.155.43 52.53.155.43

cd-21-1671-html.html

1
1. scibot 27 Aug 2022
  
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  RRID:Addgene_111177
  
  DOI: 10.1158/2159-8290.CD-21-1671
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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52.53.155.43/5e67ddaf80a7b90ec85c4b24452e48b76eabacbf/cd-21-1671-html.html
www.sciencedirect.com www.sciencedirect.com

Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal

1
1. scibot 10 Aug 2022
  
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  Plasmid_111177
  
  DOI: 10.1016/j.isci.2022.104804
  
  Resource: RRID:Addgene_111177
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004222010768