47 Matching Annotations
  1. Sep 2026
  2. www.biorxiv.org www.biorxiv.org
    A PTBP1–CDC42 splicing axis regulates leukemia growth and venetoclax sensitivity in acute myeloid leukemia
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    biorxiv.org/content/10.64898/2026.08.25.745954v1
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AURORA A interacts with DICER and SETD2 to promote S-phase progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458143/
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel anti-CD20, concabody, enhances immunotherapy efficacy by targeting MPZL1 and augmenting antibody-induced cell death
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    pmc.ncbi.nlm.nih.gov/articles/PMC13124566/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Targetable Developmental Program Coregulates Angiogenesis and Immune Evasion in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223554/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13218332/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A mechanism to initiate emergency type 2 myelopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13148993/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase HUWE1 is required for KRAS-induced lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13187489/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PIP4K2A/2B inhibitor suppresses tumor growth in a xenograft model of NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13206749/
  12. May 2026
  13. www.sciencedirect.com www.sciencedirect.com
    A regulatory circuitry driving a noradrenergic to mesenchymal transition highlights YAP/TAZ as critical players in neuroblastoma plasticity
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    sciencedirect.com/science/article/pii/S2211124726004298
  14. Apr 2026
  15. www.biorxiv.org www.biorxiv.org
    Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
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    biorxiv.org/content/10.64898/2026.04.16.718395v1
  16. www.sciencedirect.com www.sciencedirect.com
    PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes
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    sciencedirect.com/science/article/pii/S1097276526002017
  17. Mar 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905196/
  19. www.sciencedirect.com www.sciencedirect.com
    Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle
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    sciencedirect.com/science/article/pii/S0092867426001157
  20. Jan 2026
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interaction of lncRNA LENT with DHX36 regulates translation and suppresses autophagy in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12847983/
  22. www.sciencedirect.com www.sciencedirect.com
    Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia
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    sciencedirect.com/science/article/pii/S221112472501647X
  23. Dec 2025
  24. 54.241.53.176 54.241.53.176
    2025.12.02.691634.full-html.html
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    54.241.53.176/198fbbce9f086ab5db289a9a142f3485c6314e0b/2025.12.02.691634.full-html.html
  25. 54.241.53.176 54.241.53.176
    2025.11.26.690669v1.full-html.html
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    54.241.53.176/9ef3d3abc2b2bd76adadd211df788b0a57012208/2025.11.26.690669v1.full-html.html
  26. Nov 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PAX3-FOXO1 drives targetable cell state-dependent metabolic vulnerabilities in rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12477665/
  28. Sep 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
  30. Aug 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thioredoxin Reductase 1 inhibition triggers ferroptosis in KRAS-independent lung cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324224/
  32. Jul 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735329/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232590/
  35. Jun 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12169444/
  37. www.sciencedirect.com www.sciencedirect.com
    Cohesin supercoils DNA during loop extrusion
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    sciencedirect.com/science/article/pii/S2211124725006278
  38. Apr 2025
  39. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/d82b50f0340a265ea39586fdf6016ce1aa48cfa1/PDF-html.html
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962125/
  41. Mar 2025
  42. www.nature.com www.nature.com
    Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation
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    nature.com/articles/s42255-024-01201-w
  43. Sep 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11422168/
  45. Aug 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347226/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343564/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257442/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing
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    ncbi.nlm.nih.gov/pmc/articles/PMC11290012/
  50. Jul 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  52. Apr 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042198/
  54. Feb 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
  56. www.sciencedirect.com www.sciencedirect.com
    Specialized replication mechanisms maintain genome stability at human centromeres
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    sciencedirect.com/science/article/pii/S1097276524000546
  57. Aug 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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    sciencedirect.com/science/article/pii/S1097276523005671
  59. Jun 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
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    sciencedirect.com/science/article/pii/S0092867423005226
  61. Apr 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asparagine starvation suppresses histone demethylation through iron depletion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10074807/
  63. www.nature.com www.nature.com
    RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status
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    nature.com/articles/s41388-023-02683-w
  64. Jan 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9755964/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  67. Aug 2022
  68. 52.53.155.43 52.53.155.43
    cd-21-1671-html.html
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    52.53.155.43/5e67ddaf80a7b90ec85c4b24452e48b76eabacbf/cd-21-1671-html.html
  69. www.sciencedirect.com www.sciencedirect.com
    Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal
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    sciencedirect.com/science/article/pii/S2589004222010768