Hypothesis

20 Matching Annotations

Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TRIM21-mediated ubiquitination of PARP1 regulated by the PI3K/AKT-STAT5A axis suppresses small cell lung cancer

1
1. scibot 07 Aug 2026
  
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  111575
  
  DOI: 10.1038/s41467-026-73271-1
  
  Resource: RRID:Addgene_111575
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_111575
  
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  RRID:Addgene_111575
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pmc.ncbi.nlm.nih.gov/articles/PMC13434705/
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PARP1 regulates the genomic ribonucleotide processing activity of TOP1 to prevent the formation of toxic TOP1-DNA adducts and the associated mutations

1
1. scibot 10 Jun 2026
  
  in Public
  
  Addgene_111575
  
  DOI: 10.64898/2026.04.16.719024
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
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  RRID:Addgene_111575
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pmc.ncbi.nlm.nih.gov/articles/PMC13131469/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FTO suppresses DNA repair by inhibiting PARP1

1
1. scibot 07 Apr 2025
  
  in Public
  
  plasmid_111575
  
  DOI: 10.1038/s41467-025-58309-0
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
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  RRID:Addgene_111575
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pmc.ncbi.nlm.nih.gov/articles/PMC11937437/
Feb 2025
elifesciences.org elifesciences.org

SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

1
1. scibot 14 Feb 2025
  
  in Public
  
  RRID:Addgene_111575
  
  DOI: 10.7554/eLife.98152
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
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  RRID:Addgene_111575
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elifesciences.org/articles/98152
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation–dependent mechanisms

7
1. scibot 07 Feb 2025
  
  in Public
  
  111575
  
  DOI: 10.1126/sciadv.ads2919
  
  Resource: RRID:Addgene_111575
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_111575
  
  What is this?
  
  RRID:Addgene_111575
2. scibot 06 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
3. scibot 05 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
4. scibot 04 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
5. scibot 03 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
6. scibot 02 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
7. scibot 01 Feb 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11721697/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation–dependent mechanisms

5
1. scibot 31 Jan 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
2. scibot 30 Jan 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
3. scibot 29 Jan 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
4. scibot 28 Jan 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
5. scibot 27 Jan 2025
  
  in Public
  
  111575
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_111575
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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11721697/
Sep 2024
www.biorxiv.org www.biorxiv.org

Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons

1
1. scibot 28 Sep 2024
  
  in Public
  
  RRID:Addgene_111575
  
  DOI: 10.1101/2024.09.19.613927
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
  What is this?
  
  RRID:Addgene_111575
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RRID:Addgene_111575

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URL

biorxiv.org/content/10.1101/2024.09.19.613927v1
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection

1
1. scibot 23 Feb 2024
  
  in Public
  
  plasmid_111575
  
  DOI: 10.1016/j.celrep.2024.113845
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
  What is this?
  
  RRID:Addgene_111575
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RRID:Addgene_111575

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724001736
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Advances in the expression and purification of human PARP1: A user-friendly protocol

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:Addgene_111575
  
  DOI: 10.1016/j.pep.2023.106336
  
  Resource: RRID:Addgene_111575
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_111575
  
  What is this?
  
  RRID:Addgene_111575
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RRID:Addgene_111575

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scibot

URL

sciencedirect.com/science/article/pii/S1046592823001079
Jun 2022
www.sciencedirect.com www.sciencedirect.com

MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

1
1. scibot 03 Jun 2022
  
  in Public
  
  Addgene Cat# 111575
  
  DOI: 10.1016/j.celrep.2022.110879
  
  Resource: RRID:Addgene_111575
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_111575
  
  What is this?
  
  RRID:Addgene_111575
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RRID:Addgene_111575

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006544

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