Hypothesis

9 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Small molecule JRMS modulating importin-β1 chaperone activity as a therapeutic strategy reducing TDP-43 pathology

1
1. scibot 08 Oct 2026
  
  in Public
  
  Plasmid_112579
  
  DOI: 10.1016/j.neurot.2026.e00834
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12976485/
Jul 2026
www.sciencedirect.com www.sciencedirect.com

NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy model

1
1. scibot 23 Jul 2026
  
  in Public
  
  RRID:Addgene_112579
  
  DOI: 10.1016/j.isci.2026.116861
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S258900422602239X
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS

1
1. scibot 23 Nov 2025
  
  in Public
  
  plasmid_112579
  
  DOI: 10.1111/acel.70232
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12610945/
Nov 2024
www.mdpi.com www.mdpi.com

Heterogeneous Nuclear Ribonucleoprotein A1 Knockdown Alters Constituents of Nucleocytoplasmic Transport

1
1. scibot 07 Nov 2024
  
  in Public
  
  plasmid_112579
  
  DOI: 10.3390/brainsci14101039
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

mdpi.com/2076-3425/14/10/1039
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Physiological regulation of neuronal Wnt activity is essential for TDP-43 localization and function

1
1. scibot 21 Aug 2024
  
  in Public
  
  112579
  
  DOI: 10.1038/s44318-024-00156-8
  
  Resource: RRID:Addgene_112579
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11329687/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopment defects in cellular and Drosophila model

1
1. scibot 08 Mar 2024
  
  in Public
  
  S-tdTomato
  
  DOI: 10.1016/j.heliyon.2024.e26393
  
  Resource: RRID:Addgene_112579
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10906312/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

1
1. scibot 29 Jul 2023
  
  in Public
  
  Plasmid_112579
  
  DOI: 10.1016/j.immuni.2023.07.002
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S107476132300314X
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.

1
1. scibot 08 Jun 2023
  
  in Public
  
  RRID:Addgene_112579
  
  DOI: 10.1016/j.isci.2023.106957
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223010349
May 2021
www.sciencedirect.com www.sciencedirect.com

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

1
1. scibot 08 May 2021
  
  in Public
  
  RRID:Addgene_112579
  
  DOI: 10.1016/j.neuron.2020.06.027
  
  Resource: RRID:Addgene_112579
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112579
  
  What is this?
  
  RRID:Addgene_112579
Visit annotations in context

Tags

RRID:Addgene_112579

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627320304815