89 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized ND4 allotopic expression for gene therapy of Leber’s hereditary optic neuropathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13047110/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of sodium/calcium homeostasis by BacNav gene therapy rescues cardiac dysfunction in chronic heart failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC13004020/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vivo interrogation of transcriptional and epigenetic regulators of lung epithelial regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC13015491/
  5. Mar 2026
  6. www.biorxiv.org www.biorxiv.org
    Development of a recombinant adeno-associated virus vector for human T lymphocyte- and natural killer cell-targeted gene therapy
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    biorxiv.org/content/10.64898/2026.02.26.707014v1
  7. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226005560-main-html.html
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    54.241.53.176/3f9deeebafbe98264959bc85c646f95d599d5b8f/1-s2.0-S2589004226005560-main-html.html
  8. Feb 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional rescue and AI analysis of a human inactivating GPCR mutation using a small molecule
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905377/
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    An orthogonal CRISPR/Cpf1 platform for precise spatiotemporal gene regulation and osteoporotic fracture repair
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    sciencedirect.com/science/article/pii/S2667237525003352
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802539/
  12. Nov 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Senescent cells promote viral infection-associated inflammation and tissue damage through a robust NF-κB pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12560573/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A dynamic gene regulatory code drives synaptic development of hippocampal granule cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12542959/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rat somatic genome editing enables ER+ breast cancer modeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458290/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462433/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Modeling of Human Dorsal Root Ganglion Neurons for GCaMP6-Based Calcium Imaging of Sensory Responses to HSV-1 Infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12513575/
  18. Sep 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nucleosome stability safeguards cell identity, stress resilience and healthy aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12458469/
  20. www.biorxiv.org www.biorxiv.org
    Long non-coding RNA Cerox1 targets components of the mitochondrial electron transport chain to regulate the memory impairment caused by sleep deprivation
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    biorxiv.org/content/10.1101/2025.09.15.676326v1
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    Ultrabright chemical labeling enables rapid neural connectivity profiling in large tissue samples
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    sciencedirect.com/science/article/pii/S0896627325006579
  22. Aug 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained high expression of human FVII following AAV8-mediated gene delivery in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282199/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12272419/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Implantation of engineered adipocytes suppresses tumor progression in cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319119/
  26. Jul 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evaluation of transduction efficiency in pancreatic beta and alpha cells utilizing various AAV serotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214633/
  28. elifesciences.org elifesciences.org
    SIRT2 protects against Japanese encephalitis virus infection in mice
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    elifesciences.org/reviewed-preprints/106778
  29. Jun 2025
  30. www.sciencedirect.com www.sciencedirect.com
    Microfluidic synthesis of PEI/plasmid DNA polyplexes for downstream recombinant AAV vector synthesis: Physico-chemical and in vitro transfection study
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    sciencedirect.com/science/article/pii/S000925092500898X
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122587/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162853/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12137126/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intensification of rAAV Production Based on HEK293 Cell Transient Transfection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149485/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GDNF overexpression in astrocytes enhances branching and partially preserves hippocampal function in an Alzheimer’s rat model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130339/
  36. May 2025
  37. link.springer.com link.springer.com
    SFRS8 Regulates Memory by Modulating RNA Splicing of Synaptic Genes
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    link.springer.com/article/10.1007/s12035-025-05036-8
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lung Organoids from hiPSCs Can Be Efficiently Transduced by Recombinant Adeno-Associated Viral and Adenoviral Vectors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12024971/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting adenine base editing efficiencies in different cellular contexts by deep learning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12060317/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Krüppel-like factor 5 remodels lipid metabolism in exercised skeletal muscle
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    pmc.ncbi.nlm.nih.gov/articles/PMC12060515/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of Wild-Type TMEM43 Improves Cardiac Function in Arrhythmogenic Right Ventricular Cardiomyopathy Type 5
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    pmc.ncbi.nlm.nih.gov/articles/PMC11984551/
  42. Apr 2025
  43. www.biorxiv.org www.biorxiv.org
    Adeno-associated viruses escort nanomaterials to specific cells and tissues
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    biorxiv.org/content/10.1101/2025.04.04.647267v1
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225003700-main-html.html
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    SIRT2 protects against Japanese encephalitis virus infection in mice
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    biorxiv.org/content/10.1101/2025.03.24.645101v1
  46. Mar 2025
  47. pubs.acs.org pubs.acs.org
    Protein Carrier Adeno-Associated Virus
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    pubs.acs.org/doi/10.1021/acsnano.5c01498
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cardiac-Specific Gene Editing via an AAV9-Tnnt2-SaCas9-miR122TS Vector
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    pmc.ncbi.nlm.nih.gov/articles/PMC11896767/
  49. www.biorxiv.org www.biorxiv.org
    Noradrenergic efferent subsystems that gate traumatic social learning
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    biorxiv.org/content/10.1101/2025.03.07.641347v1
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC11839100/
  51. Feb 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11830570/
  53. Jan 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC11702558/
  55. Dec 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantitative proteomic analysis of residual host cell protein retention across adeno-associated virus affinity chromatography
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    pmc.ncbi.nlm.nih.gov/articles/PMC11650319/
  57. Nov 2024
  58. www.liebertpub.com www.liebertpub.com
    Focused Ultrasounds as an Adeno-Associated Virus Gene Therapy-Empowering Tool in Juvenile Mice via Intracerebroventricular Administration
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    liebertpub.com/doi/10.1089/hum.2024.108
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo
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    onlinelibrary.wiley.com/doi/10.1002/adma.202408154
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptotagmin 4 supports spontaneous axon sprouting after spinal cord injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC11502230/
  61. Sep 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biolayer interferometry for adeno-associated virus capsid titer measurement and applications to upstream and downstream process development
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    ncbi.nlm.nih.gov/pmc/articles/PMC11365433/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11434121/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11374810/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An autonucleolytic suspension HEK293F host cell line for high-titer serum-free AAV5 and AAV9 production with reduced levels of DNA impurity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11385518/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simple and highly specific targeting of resident microglia with adeno-associated virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407971/
  67. Aug 2024
  68. www.mdpi.com www.mdpi.com
    Efficient AAV9 Purification Using a Single-Step AAV9 Magnetic Affinity Beads Isolation
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    mdpi.com/1422-0067/25/15/8342
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Streamlined Adeno-Associated Virus Production Using Suspension HEK293T Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10875358/
  70. Jul 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247929/
  72. Jun 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Localized translation and sarcomere maintenance requires ribosomal protein SA in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213506/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185794/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185653/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160762/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11169449/
  78. May 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Blood–Brain Barrier Is Unaffected in the Ndufs4−/− Mouse Model of Leigh Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC11084937/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Airway basal cells from human-induced pluripotent stem cells: a new frontier in cystic fibrosis research
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    ncbi.nlm.nih.gov/pmc/articles/PMC11082282/
  81. 52.53.155.43 52.53.155.43
    Optimization of AAV vectors for transactivator-regulated enhanced gene expression within targeted neuronal populations.
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    52.53.155.43/7f9ee4f71b8a925e453a4463d9dde20f671e0e7e/PIIS2589004224011003-html.html
  82. www.sciencedirect.com www.sciencedirect.com
    Transient sensorimotor projections in the developmental song learning period
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    sciencedirect.com/science/article/pii/S2211124724005242
  83. Mar 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10979107/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing prime editor activity by directed protein evolution in yeast
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    ncbi.nlm.nih.gov/pmc/articles/PMC10920827/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10907447/
  87. www.sciencedirect.com www.sciencedirect.com
    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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    sciencedirect.com/science/article/pii/S2589004224004401
  88. Feb 2024
  89. www.biorxiv.org www.biorxiv.org
    Monosynaptically-interconnected Network Module (MNM) Approach for High-Resolution Brain Sub-Network Analysis
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    biorxiv.org/content/10.1101/2024.02.19.581007v1
  90. Jan 2024
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Accessory Protein Orf7b Induces Lung Injury via c-Myc Mediated Apoptosis and Ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10816122/
  92. www.sciencedirect.com www.sciencedirect.com
    Cortical somatostatin interneuron subtypes form cell-type-specific circuits
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    sciencedirect.com/science/article/pii/S089662732300435X
  93. Nov 2023
  94. www.nature.com www.nature.com
    A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences
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    nature.com/articles/s41467-023-42746-w
  95. Mar 2023
  96. link.springer.com link.springer.com
    Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth
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    link.springer.com/article/10.1007/s00395-023-00979-2
  97. www.biorxiv.org www.biorxiv.org
    A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences
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    biorxiv.org/content/10.1101/2023.02.21.529451v1
  98. Jan 2023
  99. link.springer.com link.springer.com
    Recombinant Adeno-associated Viral Vectors Serotypes 6 and 9 are Able to Transduce Human Tracheal Epithelial Cells but Not Human Induced Pluripotent Stem Cells
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    link.springer.com/article/10.1007/s12033-023-00668-4
  100. Dec 2022
  101. www.sciencedirect.com www.sciencedirect.com
    Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy
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    sciencedirect.com/science/article/pii/S2666166722007870
  102. Jun 2022
  103. www.sciencedirect.com www.sciencedirect.com
    Targeting miR-30d reverses pathological cardiac hypertrophy
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    sciencedirect.com/science/article/pii/S2352396422002894
  104. www.sciencedirect.com www.sciencedirect.com
    Neural circuit pathology driven by Shank3 mutation disrupts social behaviors
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    sciencedirect.com/science/article/pii/S2211124722006817
  105. Jan 2022
  106. www.sciencedirect.com www.sciencedirect.com
    Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern
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    sciencedirect.com/science/article/pii/S235239642200007X
  107. Dec 2021
  108. www.mdpi.com www.mdpi.com
    Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice
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    mdpi.com/2073-4409/10/12/3286
  109. Oct 2021
  110. www.sciencedirect.com www.sciencedirect.com
    A Fast, Aqueous, Reversible Three-Day Tissue Clearing Method for Adult and Embryonic Mouse Brain and Whole Body
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    sciencedirect.com/science/article/pii/S2667237521001454
  111. Sep 2021
  112. www.sciencedirect.com www.sciencedirect.com
    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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    sciencedirect.com/science/article/pii/S0092867421010527
  113. Apr 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
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    sciencedirect.com/science/article/pii/S1074761321001230
  115. Feb 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A simple adeno-associated virus-based approach for the generation of cardiac genetic models in rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC7863997/
  117. Dec 2020
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain
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    ncbi.nlm.nih.gov/pmc/articles/PMC7683292/