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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sustained high expression of human FVII following AAV8-mediated gene delivery in mice

1
1. scibot 11 Aug 2025
  
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  Addgene_112865
  
  DOI: 10.1016/j.omtm.2025.101523
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12282199/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice

1
1. scibot 11 Aug 2025
  
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  Addgene_112865
  
  DOI: 10.1016/j.omtm.2025.101522
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12272419/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Implantation of engineered adipocytes suppresses tumor progression in cancer models

1
1. scibot 10 Aug 2025
  
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  112865
  
  DOI: 10.1038/s41587-024-02551-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319119/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Evaluation of transduction efficiency in pancreatic beta and alpha cells utilizing various AAV serotypes

1
1. scibot 20 Jul 2025
  
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  112865
  
  DOI: 10.1038/s41598-025-05518-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12214633/
elifesciences.org elifesciences.org

SIRT2 protects against Japanese encephalitis virus infection in mice

1
1. scibot 03 Jul 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.7554/eLife.106778.1
  
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elifesciences.org/reviewed-preprints/106778
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Microfluidic synthesis of PEI/plasmid DNA polyplexes for downstream recombinant AAV vector synthesis: Physico-chemical and in vitro transfection study

1
1. scibot 21 Jun 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.ces.2025.122075
  
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sciencedirect.com/science/article/pii/S000925092500898X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combination of hydrophilic interaction liquid chromatography and top-down mass spectrometry for characterisation of adeno-associated virus capsid proteins

1
1. scibot 15 Jun 2025
  
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  112865
  
  DOI: 10.1007/s00216-025-05874-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12122587/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling

1
1. scibot 15 Jun 2025
  
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  Addgene_112865
  
  DOI: 10.1038/s44321-025-00248-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12162853/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence

1
1. scibot 14 Jun 2025
  
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  112865
  
  DOI: 10.1038/s41586-025-08809-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12137126/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intensification of rAAV Production Based on HEK293 Cell Transient Transfection

1
1. scibot 14 Jun 2025
  
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  plasmid_112865
  
  DOI: 10.1002/biot.70020
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12149485/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GDNF overexpression in astrocytes enhances branching and partially preserves hippocampal function in an Alzheimer’s rat model

1
1. scibot 11 Jun 2025
  
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  112865 Addgene
  
  DOI: 10.1038/s41598-025-02881-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12130339/
May 2025
link.springer.com link.springer.com

SFRS8 Regulates Memory by Modulating RNA Splicing of Synaptic Genes

1
1. scibot 29 May 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.1007/s12035-025-05036-8
  
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link.springer.com/article/10.1007/s12035-025-05036-8
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lung Organoids from hiPSCs Can Be Efficiently Transduced by Recombinant Adeno-Associated Viral and Adenoviral Vectors

1
1. scibot 21 May 2025
  
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  plasmid_112865
  
  DOI: 10.3390/biomedicines13040879
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12024971/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Predicting adenine base editing efficiencies in different cellular contexts by deep learning

1
1. scibot 21 May 2025
  
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  Addgene_112865
  
  DOI: 10.1186/s13059-025-03586-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12060317/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Krüppel-like factor 5 remodels lipid metabolism in exercised skeletal muscle

1
1. scibot 18 May 2025
  
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  plasmid_112865
  
  DOI: 10.1016/j.molmet.2025.102154
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12060515/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Overexpression of Wild-Type TMEM43 Improves Cardiac Function in Arrhythmogenic Right Ventricular Cardiomyopathy Type 5

1
1. scibot 16 May 2025
  
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  112865
  
  DOI: 10.1161/CIRCRESAHA.124.325848
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11984551/
Apr 2025
www.biorxiv.org www.biorxiv.org

Adeno-associated viruses escort nanomaterials to specific cells and tissues

1
1. scibot 13 Apr 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.1101/2025.04.04.647267
  
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biorxiv.org/content/10.1101/2025.04.04.647267v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

1-s2.0-S2589004225003700-main-html.html

1
1. scibot 07 Apr 2025
  
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  112865
  
  DOI: 10.1016/j.isci.2025.112110
  
  Resource: RRID:Addgene_112865
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11951025/
www.biorxiv.org www.biorxiv.org

SIRT2 protects against Japanese encephalitis virus infection in mice

1
1. scibot 03 Apr 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.1101/2025.03.24.645101
  
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biorxiv.org/content/10.1101/2025.03.24.645101v1
Mar 2025
pubs.acs.org pubs.acs.org

Protein Carrier Adeno-Associated Virus

1
1. scibot 24 Mar 2025
  
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  plasmid_112865
  
  DOI: 10.1021/acsnano.5c01498
  
  Resource: RRID:Addgene_112865
  
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pubs.acs.org/doi/10.1021/acsnano.5c01498
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cardiac-Specific Gene Editing via an AAV9-Tnnt2-SaCas9-miR122TS Vector

1
1. scibot 23 Mar 2025
  
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  112865
  
  DOI: 10.21769/BioProtoc.5235
  
  Resource: RRID:Addgene_112865
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11896767/
www.biorxiv.org www.biorxiv.org

Noradrenergic efferent subsystems that gate traumatic social learning

1
1. scibot 14 Mar 2025
  
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  RRID:Addgene_112865
  
  DOI: 10.1101/2025.03.07.641347
  
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biorxiv.org/content/10.1101/2025.03.07.641347v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex

1
1. scibot 11 Mar 2025
  
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  112865
  
  DOI: 10.1101/2025.02.07.636951
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11839100/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1

1
1. scibot 24 Feb 2025
  
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  Addgene_112865
  
  DOI: 10.1002/ctm2.70227
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11830570/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities

1
1. scibot 27 Jan 2025
  
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  plasmid_112865
  
  DOI: 10.1101/2024.12.16.628673
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11702558/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Quantitative proteomic analysis of residual host cell protein retention across adeno-associated virus affinity chromatography

1
1. scibot 27 Dec 2024
  
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  112865
  
  DOI: 10.1016/j.omtm.2024.101383
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11650319/
Nov 2024
www.liebertpub.com www.liebertpub.com

Focused Ultrasounds as an Adeno-Associated Virus Gene Therapy-Empowering Tool in Juvenile Mice via Intracerebroventricular Administration

1
1. scibot 28 Nov 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1089/hum.2024.108
  
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liebertpub.com/doi/10.1089/hum.2024.108
onlinelibrary.wiley.com onlinelibrary.wiley.com

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

2
1. scibot 15 Nov 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1002/adma.202408154
  
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2. scibot 15 Nov 2024
  
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  Addgene_112
  
  DOI: 10.1002/adma.202408154
  
  Resource: None
  
  Curator: @mzhang007
  
  SciCrunch record: RRID:Addgene_112865
  
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onlinelibrary.wiley.com/doi/10.1002/adma.202408154
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Synaptotagmin 4 supports spontaneous axon sprouting after spinal cord injury

1
1. scibot 07 Nov 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1523/JNEUROSCI.1593-23.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11502230/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Biolayer interferometry for adeno-associated virus capsid titer measurement and applications to upstream and downstream process development

1
1. scibot 29 Sep 2024
  
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  112865
  
  DOI: 10.1016/j.omtm.2024.101306
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11365433/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice

1
1. scibot 29 Sep 2024
  
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  112 865
  
  DOI: 10.1002/advs.202402412
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11434121/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation

1
1. scibot 29 Sep 2024
  
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  plasmid_112865
  
  DOI: 10.1038/s41467-024-52049-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11374810/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An autonucleolytic suspension HEK293F host cell line for high-titer serum-free AAV5 and AAV9 production with reduced levels of DNA impurity

1
1. scibot 28 Sep 2024
  
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  112865
  
  DOI: 10.1016/j.omtm.2024.101317
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11385518/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Simple and highly specific targeting of resident microglia with adeno-associated virus

1
1. scibot 25 Sep 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.isci.2024.110706
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11407971/
Aug 2024
www.mdpi.com www.mdpi.com

Efficient AAV9 Purification Using a Single-Step AAV9 Magnetic Affinity Beads Isolation

1
1. scibot 19 Aug 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.3390/ijms25158342
  
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mdpi.com/1422-0067/25/15/8342
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Streamlined Adeno-Associated Virus Production Using Suspension HEK293T Cells

1
1. scibot 02 Aug 2024
  
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  112865
  
  DOI: 10.21769/BioProtoc.4931
  
  Resource: RRID:Addgene_112865
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10875358/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity

1
1. scibot 27 Jul 2024
  
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  plasmid_112865
  
  DOI: 10.21203/rs.3.rs-4530873/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11247929/
Jun 2024
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Localized translation and sarcomere maintenance requires ribosomal protein SA in mice

1
1. scibot 30 Jun 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1172/JCI174527
  
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Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In Vivo

1
1. scibot 27 Jun 2024
  
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  RRID:Addgene_112865
  
  DOI: 10.1101/2024.06.07.598004
  
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Neurogliaform Cells Exhibit Laminar-specific Responses in the Visual Cortex and Modulate Behavioral State-dependent Cortical Activity

1
1. scibot 27 Jun 2024
  
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  plasmid_112865
  
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AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model

1
1. scibot 20 Jun 2024
  
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Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice

1
1. scibot 15 Jun 2024
  
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  DOI: 10.1038/s41467-024-48430-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11169449/
May 2024
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The Blood–Brain Barrier Is Unaffected in the Ndufs4−/− Mouse Model of Leigh Syndrome

1
1. scibot 12 May 2024
  
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  DOI: 10.3390/ijms25094828
  
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Airway basal cells from human-induced pluripotent stem cells: a new frontier in cystic fibrosis research

1
1. scibot 12 May 2024
  
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  plasmid_112865
  
  DOI: 10.3389/fcell.2024.1336392
  
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Optimization of AAV vectors for transactivator-regulated enhanced gene expression within targeted neuronal populations.

1
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Transient sensorimotor projections in the developmental song learning period

1
1. scibot 09 May 2024
  
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  RRID: Addgene_112865
  
  DOI: 10.1016/j.celrep.2024.114196
  
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Mar 2024
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Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection

1
1. scibot 31 Mar 2024
  
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Enhancing prime editor activity by directed protein evolution in yeast

1
1. scibot 17 Mar 2024
  
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  DOI: 10.1038/s41467-024-46107-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10920827/
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Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice

1
1. scibot 08 Mar 2024
  
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  pAAV2/9n
  
  DOI: 10.1007/s11481-024-10107-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10907447/
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Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

3
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Feb 2024
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Monosynaptically-interconnected Network Module (MNM) Approach for High-Resolution Brain Sub-Network Analysis

1
1. scibot 29 Feb 2024
  
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  DOI: 10.1101/2024.02.19.581007
  
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biorxiv.org/content/10.1101/2024.02.19.581007v1
Jan 2024
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SARS-CoV-2 Accessory Protein Orf7b Induces Lung Injury via c-Myc Mediated Apoptosis and Ferroptosis

1
1. scibot 29 Jan 2024
  
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Cortical somatostatin interneuron subtypes form cell-type-specific circuits

1
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  plasmid_112865
  
  DOI: 10.1016/j.neuron.2023.05.032
  
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sciencedirect.com/science/article/pii/S089662732300435X
Nov 2023
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A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences

1
1. scibot 25 Nov 2023
  
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  RRID:Addgene_112865
  
  DOI: 10.1038/s41467-023-42746-w
  
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nature.com/articles/s41467-023-42746-w
Mar 2023
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Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth

2
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  RRID:Addgene_112865
  
  DOI: 10.1007/s00395-023-00979-2
  
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  DOI: 10.1007/s00395-023-00979-2
  
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A toolbox of astrocyte-specific, serotype-independent adeno-associated viral vectors using microRNA targeting sequences

1
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  RRID:Addgene_112865
  
  DOI: 10.1101/2023.02.21.529451
  
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biorxiv.org/content/10.1101/2023.02.21.529451v1
Jan 2023
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Recombinant Adeno-associated Viral Vectors Serotypes 6 and 9 are Able to Transduce Human Tracheal Epithelial Cells but Not Human Induced Pluripotent Stem Cells

1
1. scibot 31 Jan 2023
  
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  DOI: 10.1007/s12033-023-00668-4
  
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link.springer.com/article/10.1007/s12033-023-00668-4
Dec 2022
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Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy

1
1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.xpro.2022.101907
  
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sciencedirect.com/science/article/pii/S2666166722007870
Jun 2022
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Targeting miR-30d reverses pathological cardiac hypertrophy

1
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  DOI: 10.1016/j.ebiom.2022.104108
  
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Neural circuit pathology driven by Shank3 mutation disrupts social behaviors

1
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.celrep.2022.110906
  
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sciencedirect.com/science/article/pii/S2211124722006817
Jan 2022
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Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern

1
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.ebiom.2022.103818
  
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sciencedirect.com/science/article/pii/S235239642200007X
Dec 2021
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Neuronal Menin Overexpression Rescues Learning and Memory Phenotype in CA1-Specific α7 nAChRs KD Mice

1
1. scibot 01 Dec 2021
  
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  RRID:Addgene_112865
  
  DOI: 10.3390/cells10123286
  
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mdpi.com/2073-4409/10/12/3286
Oct 2021
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A Fast, Aqueous, Reversible Three-Day Tissue Clearing Method for Adult and Embryonic Mouse Brain and Whole Body

2
1. scibot 12 Oct 2021
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.crmeth.2021.100090
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.crmeth.2021.100090
  
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sciencedirect.com/science/article/pii/S2667237521001454
Sep 2021
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Revisiting astrocyte to neuron conversion with lineage tracing in vivo

1
1. scibot 28 Sep 2021
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.cell.2021.09.005
  
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sciencedirect.com/science/article/pii/S0092867421010527
Apr 2021
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Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING

1
1. scibot 15 Apr 2021
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.immuni.2021.03.011
  
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sciencedirect.com/science/article/pii/S1074761321001230
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A simple adeno-associated virus-based approach for the generation of cardiac genetic models in rats

1
1. scibot 24 Feb 2021
  
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  RRID:Addgene_112865
  
  DOI: 10.12688/f1000research.27675.1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7863997/
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain

1
1. scibot 09 Dec 2020
  
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  RRID:Addgene_112865
  
  DOI: 10.1016/j.omtm.2020.10.011
  
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