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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Modulation of AAV transduction and integration targeting by topoisomerase poisons
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    1. scibot 15 Nov 2024
      plasmid no. 112867

      DOI: 10.1016/j.omtm.2024.101364

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    sciencedirect.com/science/article/pii/S2329050124001803
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication
    1
    1. scibot 29 Sep 2024
      112867

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    ncbi.nlm.nih.gov/pmc/articles/PMC11343251/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biolayer interferometry for adeno-associated virus capsid titer measurement and applications to upstream and downstream process development
    1
    1. scibot 29 Sep 2024
      112867

      DOI: 10.1016/j.omtm.2024.101306

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    ncbi.nlm.nih.gov/pmc/articles/PMC11365433/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HSF5 Deficiency Causes Male Infertility Involving Spermatogenic Arrest at Meiotic Prophase I in Humans and Mice
    1
    1. scibot 29 Sep 2024
      112 867

      DOI: 10.1002/advs.202402412

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    ncbi.nlm.nih.gov/pmc/articles/PMC11434121/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells
    1
    1. scibot 28 Sep 2024
      pAdDeltaF6

      DOI: 10.1007/s00253-024-13281-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11374875/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An autonucleolytic suspension HEK293F host cell line for high-titer serum-free AAV5 and AAV9 production with reduced levels of DNA impurity
    1
    1. scibot 28 Sep 2024
      112867

      DOI: 10.1016/j.omtm.2024.101317

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    ncbi.nlm.nih.gov/pmc/articles/PMC11385518/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHISA3 Reprograms Tumor‐Associated Macrophages Toward an Antitumoral Phenotype and Enhances Cancer Immunotherapy
    1
    1. scibot 27 Sep 2024
      112867

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    ncbi.nlm.nih.gov/pmc/articles/PMC11423144/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans
    1
    1. scibot 26 Sep 2024
      pAD-Δf6

      DOI: 10.1007/s00125-024-06193-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11410908/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simple and highly specific targeting of resident microglia with adeno-associated virus
    1
    1. scibot 25 Sep 2024
      RRID:Addgene_112867

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    ncbi.nlm.nih.gov/pmc/articles/PMC11407971/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of KDM6B mosaic brain knockout on synaptic function and behavior
    1
    1. scibot 05 Sep 2024
      RRID:Addgene_112867

      DOI: 10.1038/s41598-024-70728-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11369245/
  13. Aug 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes
    1
    1. scibot 20 Aug 2024
      Addgene # 112867

      DOI: 10.1016/j.celrep.2024.114637

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    sciencedirect.com/science/article/pii/S2211124724009872
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell discovery of m6A RNA modifications in the hippocampus
    1
    1. scibot 18 Aug 2024
      112867

      DOI: 10.1101/gr.278424.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293556/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-relevant upregulation of P2Y1 receptor in astrocytes enhances neuronal excitability via IGFBP2
    1
    1. scibot 18 Aug 2024
      112867

      DOI: 10.1038/s41467-024-50190-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310333/
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Adenosine A2B receptors differently modulate oligodendrogliogenesis and myelination depending on their cellular localization
    1
    1. scibot 13 Aug 2024
      #112867, Addgene

      DOI: 10.1002/glia.24593

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    onlinelibrary.wiley.com/doi/10.1002/glia.24593
  18. www.cell.com www.cell.com
    Kainate receptors regulate synaptic integrity and plasticity by forming a complex with synaptic organizers in the cerebellum
    1
    1. scibot 13 Aug 2024
      Addgene_112867

      DOI: 10.1016/j.celrep.2024.114427

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    cell.com/cell-reports/fulltext/S2211-1247(24)00756-3
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
    1
    1. scibot 02 Aug 2024
      112867

      DOI: 10.1016/j.xcrm.2024.101413

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897598/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Streamlined Adeno-Associated Virus Production Using Suspension HEK293T Cells
    1
    1. scibot 02 Aug 2024
      112867

      DOI: 10.21769/BioProtoc.4931

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    ncbi.nlm.nih.gov/pmc/articles/PMC10875358/
  21. Jun 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Localized translation and sarcomere maintenance requires ribosomal protein SA in mice
    1
    1. scibot 30 Jun 2024
      RRID:Addgene_112867

      DOI: 10.1172/JCI174527

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    ncbi.nlm.nih.gov/pmc/articles/PMC11213506/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior
    1
    1. scibot 20 Jun 2024
      112867

      DOI: 10.1038/s41467-024-49336-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11176395/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice
    1
    1. scibot 15 Jun 2024
      plasmid_112867

      DOI: 10.1038/s41467-024-48430-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11169449/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploring Ca2+ Dynamics in Myelinating Oligodendrocytes through rAAV-Mediated jGCaMP8s Expression in Developing Spinal Cord Organ Cultures
    1
    1. scibot 10 Jun 2024
      112867

      DOI: 10.1523/ENEURO.0540-23.2024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11151195/
  26. May 2024
  27. www.biorxiv.org www.biorxiv.org
    Redox-dependent synaptic clustering of gephyrin
    1
    1. scibot 29 May 2024
      RRID: Addgene_112867

      DOI: 10.1101/2024.03.15.585209

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    biorxiv.org/content/10.1101/2024.03.15.585209v1
  28. www.biorxiv.org www.biorxiv.org
    Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity
    1
    1. scibot 10 May 2024
      RRID:Addgene_112867

      DOI: 10.1101/2024.01.27.577372

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    biorxiv.org/content/10.1101/2024.01.27.577372v1
  29. www.sciencedirect.com www.sciencedirect.com
    ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
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    1. scibot 08 May 2024
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    sciencedirect.com/science/article/pii/S1934590924001413
  30. www.sciencedirect.com www.sciencedirect.com
    Transient sensorimotor projections in the developmental song learning period
    1
    1. scibot 08 May 2024
      RRID:Addgene_112867

      DOI: 10.1016/j.celrep.2024.114196

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    sciencedirect.com/science/article/pii/S2211124724005242
  31. www.sciencedirect.com www.sciencedirect.com
    Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
    1
    1. scibot 07 May 2024
      RRID:Addgene_112867

      DOI: 10.1016/j.xcrm.2024.101546

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    sciencedirect.com/science/article/pii/S2666379124002386
  32. www.nature.com www.nature.com
    Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins
    1
    1. scibot 03 May 2024
      RRID:Addgene_112867

      DOI: 10.1038/s41590-024-01820-1

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    nature.com/articles/s41590-024-01820-1
  33. Apr 2024
  34. www.cell.com www.cell.com
    Astrocyte-secreted neurocan controls inhibitory synapse formation and function
    1
    1. scibot 04 Apr 2024
      plasmid No. 112867; Addgene

      DOI: 10.1016/j.neuron.2024.03.007

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    cell.com/neuron/fulltext/S0896-6273(24)00161-2
  35. Mar 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Producing high-quantity and high-quality recombinant adeno-associated virus by low-cis triple transfection
    1
    1. scibot 31 Mar 2024
      Addgene_112867

      DOI: 10.1016/j.omtm.2024.101230

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979107/
  37. www.biorxiv.org www.biorxiv.org
    Deciphering the Role of Aggrecan in Parvalbumin Interneurons: Unexpected Outcomes from a Conditional ACAN Knockout That Eliminates WFA+ Perineuronal Nets
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    1. scibot 28 Mar 2024
      RRID:Addgene_112867

      DOI: 10.1101/2024.03.20.585910

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    biorxiv.org/content/10.1101/2024.03.20.585910v1
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing prime editor activity by directed protein evolution in yeast
    1
    1. scibot 17 Mar 2024
      112867

      DOI: 10.1038/s41467-024-46107-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920827/
  39. www.sciencedirect.com www.sciencedirect.com
    Type-I-interferon-responsive microglia shape cortical development and behavior
    2
    1. scibot 15 Mar 2024
      RRID:Addgene_112867

      DOI: 10.1016/j.cell.2024.02.020

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      RRID:Addgene_112867

      DOI: 10.1016/j.cell.2024.02.020

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    sciencedirect.com/science/article/pii/S0092867424001867
  40. www.sciencedirect.com www.sciencedirect.com
    Modular vector assembly enables rapid assessment of emerging CRISPR technologies
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    1. scibot 14 Mar 2024
      Addgene 112867

      DOI: 10.1016/j.xgen.2024.100519

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    sciencedirect.com/science/article/pii/S2666979X24000600
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
    1
    1. scibot 12 Mar 2024
      Addgene_112867

      DOI: 10.1016/j.xcrm.2024.101413

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897598/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Complement C3 From Astrocytes Plays Significant Roles in Sustained Activation of Microglia and Cognitive Dysfunctions Triggered by Systemic Inflammation After Laparotomy in Adult Male Mice
    1
    1. scibot 08 Mar 2024
      pAdDeltaF6

      DOI: 10.1007/s11481-024-10107-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907447/
  43. www.sciencedirect.com www.sciencedirect.com
    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
    1
    1. scibot 07 Mar 2024
      Addgene112867

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    sciencedirect.com/science/article/pii/S2589004224004401
  44. Feb 2024
  45. www.sciencedirect.com www.sciencedirect.com
    Long-term, high-resolution in vivo calcium imaging in pigeons
    1
    1. scibot 21 Feb 2024
      AddgeneCat#112867

      DOI: 10.1016/j.crmeth.2024.100711

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    sciencedirect.com/science/article/pii/S2667237524000262
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells
    1
    1. scibot 08 Feb 2024
      plasmid_112867

      DOI: 10.1038/s41422-023-00896-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10770082/
  47. Jan 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Accessory Protein Orf7b Induces Lung Injury via c-Myc Mediated Apoptosis and Ferroptosis
    1
    1. scibot 29 Jan 2024
      112867

      DOI: 10.3390/ijms25021157

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    ncbi.nlm.nih.gov/pmc/articles/PMC10816122/
  49. Dec 2023
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhancement of adeno-associated virus serotype 6 transduction into T cells with cell-penetrating peptides
    1
    1. scibot 02 Dec 2023
      RRID:Addgene_112867

      DOI: 10.1002/jgm.3627

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    onlinelibrary.wiley.com/doi/10.1002/jgm.3627
  51. Nov 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model
    1
    1. scibot 03 Nov 2023
      plasmid_112867

      DOI: 10.1016/j.cell.2023.10.004

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  53. www.sciencedirect.com www.sciencedirect.com
    An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
    1
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      plasmid_112867

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  54. Aug 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KMT2C knockout generates ASD-like behaviors in mice
    1
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      RRID:Addgene_112867

      DOI: 10.3389/fcell.2023.1227723

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  56. Jul 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo
    1
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  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Production of adeno-associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities
    1
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      RRID:Addgene_112867

      DOI: 10.1002/biot.202300051

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    onlinelibrary.wiley.com/doi/10.1002/biot.202300051
  59. Jun 2023
  60. www.biorxiv.org www.biorxiv.org
    Scalable, cell type-selective in vivo AAV-based CRISPR screens in mice
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      RRID:Addgene_112867

      DOI: 10.1101/2023.06.13.544831

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    biorxiv.org/content/10.1101/2023.06.13.544831v1
  61. www.biorxiv.org www.biorxiv.org
    KMT2C knockout generates ASD-like behaviors in mice
    1
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    biorxiv.org/content/10.1101/2023.05.26.542423v1
  62. May 2023
  63. www.authorea.com www.authorea.com
    High-cell-density production of adeno-associated viral vector serotype 6 by triple transfection in suspension HEK293 cell cultures
    1
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      RRID:Addgene_112867

      DOI: 10.22541/au.167535214.41739207/v1

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    authorea.com/users/582383/articles/622468-high-cell-density-production-of-adeno-associated-viral-vector-serotype-6-by-triple-transfection-in-suspension-hek293-cell-cultures
  64. Apr 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Berberine activates PPARδ and promotes gut microbiota-derived butyric acid to suppress hepatocellular carcinoma
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  66. www.nature.com www.nature.com
    Role of TMEM100 in mechanically insensitive nociceptor un-silencing
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  67. Mar 2023
  68. www.biorxiv.org www.biorxiv.org
    The molecular mechanism and physiological role of silent nociceptor activation
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  69. Feb 2023
  70. www.nature.com www.nature.com
    An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice
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  71. Jan 2023
  72. link.springer.com link.springer.com
    Recombinant Adeno-associated Viral Vectors Serotypes 6 and 9 are Able to Transduce Human Tracheal Epithelial Cells but Not Human Induced Pluripotent Stem Cells
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      RRID:Addgene_112867

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  73. www.eneuro.org www.eneuro.org
    Automated Image Analysis Reveals Different Localization of Synaptic Gephyrin C4 Splice Variants
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  74. Dec 2022
  75. www.sciencedirect.com www.sciencedirect.com
    Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy
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  76. Nov 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Neural circuit-specific gene manipulation in mouse brain in vivo using split-intein-mediated split-Cre system
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  78. Jul 2022
  79. www.sciencedirect.com www.sciencedirect.com
    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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      Plasmid_112867

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    sciencedirect.com/science/article/pii/S1097276522006530
  80. Jun 2022
  81. www.sciencedirect.com www.sciencedirect.com
    Targeting miR-30d reverses pathological cardiac hypertrophy
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      Addgene #112867

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  82. www.sciencedirect.com www.sciencedirect.com
    Neural circuit pathology driven by Shank3 mutation disrupts social behaviors
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    sciencedirect.com/science/article/pii/S2211124722006817
  83. May 2022
  84. www.sciencedirect.com www.sciencedirect.com
    Cholesterol determines the cytosolic entry and seeded aggregation of tau
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      AddgeneCat# 112867

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    sciencedirect.com/science/article/pii/S221112472200540X
  85. Mar 2022
  86. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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      AddgeneCat#112867

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    sciencedirect.com/science/article/pii/S1550413122000535
  87. Jan 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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      RRID:Addgene_112867

      DOI: 10.1038/s41467-021-27869-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC8758788/
  89. Nov 2021
  90. www.sciencedirect.com www.sciencedirect.com
    OGDHL Ameliorates Cognitive Impairment and Alzheimer's Disease-Like Pathology via Activating Wnt/β-catenin signaling in Alzheimer's Disease Mice
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      RRID:Addgene_112867

      DOI: 10.1016/j.bbr.2021.113673

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    sciencedirect.com/science/article/pii/S0166432821005611
  91. www.sciencedirect.com www.sciencedirect.com
    Protocol for evaluating the role of a gene in protecting mouse retinal ganglion cells
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      Cat# 112867

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    sciencedirect.com/science/article/pii/S2666166721006389
  92. Oct 2021
  93. www.sciencedirect.com www.sciencedirect.com
    A Fast, Aqueous, Reversible Three-Day Tissue Clearing Method for Adult and Embryonic Mouse Brain and Whole Body
    1
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      RRID:Addgene_112867

      DOI: 10.1016/j.crmeth.2021.100090

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    sciencedirect.com/science/article/pii/S2667237521001454
  94. Sep 2021
  95. www.sciencedirect.com www.sciencedirect.com
    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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      RRID:Addgene_112867

      DOI: 10.1016/j.cell.2021.09.005

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    sciencedirect.com/science/article/pii/S0092867421010527
  96. www.nature.com www.nature.com
    Compact RNA editors with small Cas13 proteins
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      RRID:Addgene_112867

      DOI: 10.1038/s41587-021-01030-2

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    nature.com/articles/s41587-021-01030-2
  97. Jul 2021
  98. www.sciencedirect.com www.sciencedirect.com
    Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models
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      plasmid_112867

      DOI: 10.1016/j.neuron.2021.06.005

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    sciencedirect.com/science/article/pii/S0896627321004207
  99. Apr 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
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      RRID:Addgene_112867

      DOI: 10.1016/j.immuni.2021.03.011

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    sciencedirect.com/science/article/pii/S1074761321001230
  101. Feb 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A simple adeno-associated virus-based approach for the generation of cardiac genetic models in rats
    1
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      RRID:Addgene_112867

      DOI: 10.12688/f1000research.27675.1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7863997/
  103. Dec 2020
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain
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      DOI: 10.1016/j.omtm.2020.10.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC7683292/
  105. Jan 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Programmable RNA-Guided RNA Effector Proteins Built from Human Parts
    1
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      RRID:Addgene_112867

      DOI: 10.1016/j.cell.2019.05.049

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