229 Matching Annotations
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    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
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    1. scibot 23 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014665/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin
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    1. scibot 23 Apr 2024
      pRSV-Rev

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019955/
  4. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
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    1. scibot 19 Apr 2024
      RRID:Addgene_12253

      DOI: 10.1158/0008-5472.CAN-23-0910

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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  5. aacrjournals.org aacrjournals.org
    Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors
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    1. scibot 19 Apr 2024
      RRID:Addgene_12253

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    aacrjournals.org/cancerres/article/84/1/84/731816/Hypoxia-Responsive-CAR-T-Cells-Exhibit-Reduced
  6. Apr 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    1. scibot 16 Apr 2024
      RRID:Addgene_12253

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    sciencedirect.com/science/article/pii/S221112472400439X
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    Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network
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      12,253

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945021/
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    Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons
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    1. scibot 15 Apr 2024
      pRSV-Rev

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    Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
    1
    1. scibot 15 Apr 2024
      12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881158/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
    1
    1. scibot 15 Apr 2024
      Addgene_12253

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    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
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    1. scibot 14 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983104/
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    Mesenchymal glioma stem cells trigger vasectasia—distinct neovascularization process stimulated by extracellular vesicles carrying EGFR
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    1. scibot 13 Apr 2024
      12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC10991552/
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    Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons
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    1. scibot 13 Apr 2024
      12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC11006854/
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    FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
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    1. scibot 13 Apr 2024
      12253

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    The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
    1
    1. scibot 13 Apr 2024
      RRID:Addgene_12253

      DOI: 10.1128/mbio.00499-24

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    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
    1
    1. scibot 09 Apr 2024
      Addgene_12253

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    sciencedirect.com/science/article/pii/S0092867424003064
  18. Mar 2024
  19. www.sciencedirect.com www.sciencedirect.com
    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
    1
    1. scibot 28 Mar 2024
      12253, Addgene

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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    1. scibot 28 Mar 2024
      Addgene plasmid#12253

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    sciencedirect.com/science/article/pii/S2211124724003309
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    A gut-derived hormone regulates cholesterol metabolism
    1
    1. scibot 19 Mar 2024
      RRID: Addgene_12253

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    sciencedirect.com/science/article/pii/S0092867424002265
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
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    Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2
    1
    1. scibot 17 Mar 2024
      12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924942/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered biosensor enables dynamic aspartate measurements in living cells
    1
    1. scibot 17 Mar 2024
      12253

      DOI: 10.7554/eLife.90024

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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Estrogen Receptor Dimerization BRET-Based Biosensors for Screening Estrogenic Endocrine-Disrupting Chemicals
    1
    1. scibot 17 Mar 2024
      12253

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    The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability
    1
    1. scibot 17 Mar 2024
      plasmid_12253

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    CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression
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    1. scibot 17 Mar 2024
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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      RRID:Addgene_12253

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scAbsolute: measuring single-cell ploidy and replication status
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
    1
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      pRSV-Rev

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  31. Feb 2024
  32. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
    1
    1. scibot 29 Feb 2024
      AddgeneCat#12253

      DOI: 10.1016/j.molcel.2024.02.002

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    sciencedirect.com/science/article/pii/S1097276524000984
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    The proteomic landscape of genotoxic stress-induced micronuclei
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    1. scibot 29 Feb 2024
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for antibody recognition of the proximal MUC16 ectodomain
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      pRSV-Rev

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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma
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    Production of infectious reporter murine norovirus by VP2 trans-complementation
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    1. scibot 29 Feb 2024
      pRSV-Rev

      DOI: 10.1128/jvi.01261-23

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POZ/BTB and AT hook containing zinc finger 1 (PATZ1) suppresses differentiation and regulates metabolism in human embryonic stem cells
    1
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      REV

      DOI: 10.7150/ijbs.83927

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
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    1. scibot 29 Feb 2024
      pRSV-rev

      DOI: 10.1038/s42003-024-05817-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams
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      12253

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881528/
  42. link.springer.com link.springer.com
    Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins
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      plasmid_12253

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    link.springer.com/article/10.1038/s41598-024-54705-6
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer
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      pRSV-Rev

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  44. www.sciencedirect.com www.sciencedirect.com
    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
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      RRID:Addgene_12253

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    sciencedirect.com/science/article/pii/S2211124724001256
  45. www.biorxiv.org www.biorxiv.org
    PTPRZ1-targeting RNA CAR-T cells exert antigen-specific and bystander antitumor activity in glioblastoma
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    1. scibot 15 Feb 2024
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      DOI: 10.1101/2023.12.23.573190

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    biorxiv.org/content/10.1101/2023.12.23.573190v1
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    Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
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    ncbi.nlm.nih.gov/pmc/articles/PMC10864035/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
    1
    1. scibot 15 Feb 2024
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  48. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
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  49. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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    1. scibot 09 Feb 2024
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
    1
    1. scibot 08 Feb 2024
      pRSV-Rev

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    ncbi.nlm.nih.gov/pmc/articles/PMC10782643/
  51. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress
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    1. scibot 01 Feb 2024
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
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      pRSV-REV

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    ncbi.nlm.nih.gov/pmc/articles/PMC10826106/
  54. Jan 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBL2 represses the transcriptional activity of Multicilin to inhibit multiciliogenesis
    1
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICH deficiency limits the progression of MYC-induced B-cell lymphoma
    1
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein
    1
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  58. www.mdpi.com www.mdpi.com
    Exo70 Promotes the Invasion of Pancreatic Cancer Cells via the Regulation of Exosomes
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      DOI: 10.3390/cancers16020336

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  59. link.springer.com link.springer.com
    Selective gene expression maintains human tRNA anticodon pools during differentiation
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  60. www.sciencedirect.com www.sciencedirect.com
    PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis
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  61. Dec 2023
  62. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
    2
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  63. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    1. scibot 20 Dec 2023
      Addgene Cat: 12253

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  64. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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      DOI: 10.1038/s41594-023-01159-5

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  65. Nov 2023
  66. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
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      RRID:Addgene_12253

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    sciencedirect.com/science/article/pii/S2090123223003612
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer
    1
    1. scibot 26 Nov 2023
      plasmid_12253

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  68. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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      RRID:Addgene_12

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    sciencedirect.com/science/article/pii/S1368764623000985
  69. Oct 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Regulation of STING activity in DNA sensing by ISG15 modification
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      RRID: Addgene_12253

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  71. www.sciencedirect.com www.sciencedirect.com
    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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      RRID: Addgene_12253

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
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    1. scibot 26 Oct 2023
      Plasmid_12253

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  73. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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      DOI: 10.1038/s41420-023-01639-z

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  74. Sep 2023
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Insights into product and process related challenges of lentiviral vector bioprocessing
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      DOI: 10.1002/bit.28498

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  76. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity
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      plasmid_12253

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    sciencedirect.com/science/article/pii/S2589004223018503
  77. 52.53.155.43 52.53.155.43
    vdad120-html.html
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    52.53.155.43/6d7222f39ce6ff806d6be40a37ce30f7488ce63a/vdad120-html.html
  78. www.biorxiv.org www.biorxiv.org
    TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling
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      DOI: 10.1101/2023.09.04.556165

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    biorxiv.org/content/10.1101/2023.09.04.556165v1
  79. Aug 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
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      RRID:Addgene_12253

      DOI: 10.1016/j.xgen.2023.100399

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  81. www.biorxiv.org www.biorxiv.org
    Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins
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      plasmid_12253

      DOI: 10.1101/2023.08.18.553740

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  82. www.sciencedirect.com www.sciencedirect.com
    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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  83. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
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  84. www.sciencedirect.com www.sciencedirect.com
    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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  85. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    3
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  86. Jul 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration
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      plasmid_12253

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  88. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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  89. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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      RRID:Addgene_12253

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coding and non-coding elements comprise a regulatory network controlling transcription in Kaposi’s sarcoma-associated herpesvirus
    1
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      plasmid_12253

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  91. pubs.acs.org pubs.acs.org
    SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
    1
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      RRID:Addgene_12253

      DOI: 10.1021/acsnano.3c01916

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  92. 52.53.155.43 52.53.155.43
    cir-22-0815-html.html
    1
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      RRID: Addgene_12253

      DOI: 10.1158/2326-6066.CIR-22-0815

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  93. Jun 2023
  94. www.sciencedirect.com www.sciencedirect.com
    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
    1
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      Addgene_12253

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  95. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
    1
    1. scibot 23 Jun 2023
      plasmid_12253

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  96. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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    1. scibot 22 Jun 2023
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      DOI: 10.1101/2023.06.14.544493

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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
    1
    1. scibot 17 Jun 2023
      Addgene_12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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      DOI: 10.26508/lsa.202301964

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    ncbi.nlm.nih.gov/pmc/articles/PMC10264968/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of the gut microbiota confers cisplatin resistance in epithelial ovarian cancer
    1
    1. scibot 17 Jun 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9772178/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
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  101. dx.doi.org dx.doi.org
    Targeting RNA exonuclease XRN1 potentiates efficacy of cancer immunotherapy
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    dx.doi.org/10.1158/0008-5472.CAN-21-3052
  102. May 2023
  103. www.embopress.org www.embopress.org
    Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry
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    1. scibot 28 May 2023
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    embopress.org/doi/10.15252/embj.2022112095
  104. www.sciencedirect.com www.sciencedirect.com
    Actuation of single downstream nodes in growth factor network steers immune cell migration
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    1. scibot 24 May 2023
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  105. www.mdpi.com www.mdpi.com
    Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV
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      DOI: 10.3390/vaccines11050977

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  106. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A rabies virus–based toolkit for efficient retrograde... : Neural Regeneration Research
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    1. scibot 06 May 2023
      Addgene, Cat# 12253

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  108. www.sciencedirect.com www.sciencedirect.com
    TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation SIRT1/p53
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    sciencedirect.com/science/article/pii/S0006291X23005508
  109. Apr 2023
  110. www.nature.com www.nature.com
    Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2
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    1. scibot 18 Apr 2023
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    nature.com/articles/s41556-023-01118-8
  111. Mar 2023
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals
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    1. scibot 24 Mar 2023
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
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    1. scibot 10 Mar 2023
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  114. Feb 2023
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity
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  117. Jan 2023
  118. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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    1. scibot 26 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124723000530
  119. www.sciencedirect.com www.sciencedirect.com
    Protocol to study presynaptic protein synthesis in ex vivo mouse hippocampal slices using HaloTag technology
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    1. scibot 21 Jan 2023
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    sciencedirect.com/science/article/pii/S2666166722008668
  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute COG inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles
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    onlinelibrary.wiley.com/doi/10.1111/tra.12876
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
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    1. scibot 07 Jan 2023
      RRID:Addgene_12253

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  122. Dec 2022
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
    1
    1. scibot 31 Dec 2022
      RRID:Addgene_12253

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    ncbi.nlm.nih.gov/pmc/articles/PMC9765453/
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor necrosis factor is a necroptosis-associated alarmin
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    1. scibot 30 Dec 2022
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  125. www.sciencedirect.com www.sciencedirect.com
    The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER
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    sciencedirect.com/science/article/pii/S2211124722017648
  126. www.sciencedirect.com www.sciencedirect.com
    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury
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    sciencedirect.com/science/article/pii/S2211124722017405
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and Analysis of hTERT-RPE1 VPS54 Knock-Out and Rescued Cell Lines
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  128. link.springer.com link.springer.com
    Rapid COG Depletion in Mammalian Cell by Auxin-Inducible Degradation System
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  129. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  130. 52.53.155.43 52.53.155.43
    can-22-0455-html.html
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  131. Nov 2022
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell-intrinsic differences between human airway epithelial cells from children and adults
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  133. www.sciencedirect.com www.sciencedirect.com
    Systematic generation and imaging of tandem repeats reveal base-pairing properties that promote RNA aggregation
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      Plasmid_12253

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  134. Oct 2022
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral vector mediated gene therapy for type I Dent disease effectively ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice
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  136. journals.asm.org journals.asm.org
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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  138. www.sciencedirect.com www.sciencedirect.com
    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
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  139. Sep 2022
  140. www.sciencedirect.com www.sciencedirect.com
    Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing
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  141. www.sciencedirect.com www.sciencedirect.com
    S1-END-seq reveals DNA secondary structures in human cells
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  142. Aug 2022
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPR-Cas12a-based diagnostic method for multiple genotypes of severe fever with thrombocytopenia syndrome virus
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent bulk release of human cytomegalovirus
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  146. academic.oup.com academic.oup.com
    FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations
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      DOI: 10.1093/nar/gkac673

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac673/6654407
  147. Jul 2022
  148. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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  149. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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  151. Jun 2022
  152. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    sciencedirect.com/science/article/pii/S2211124722007811
  153. May 2022
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    Synthetic Carbohydrate Binding Agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2.
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  156. Apr 2022
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    Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
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    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
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  159. Mar 2022
  160. www.nature.com www.nature.com
    Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples
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  161. www.sciencedirect.com www.sciencedirect.com
    Generation of highly pure motor neurons from human induced pluripotent stem cells
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells
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  165. elifesciences.org elifesciences.org
    Pathway-specific effects of ADSL deficiency on neurodevelopment
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  166. Feb 2022
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
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  169. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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  170. www.sciencedirect.com www.sciencedirect.com
    Development of human alveolar epithelial cell models to study distal lung biology and disease
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  171. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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  172. journals.biologists.com journals.biologists.com
    Contribution of protein-protein interactions to the endothelial barrier-stabilizing function of KRIT1
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  173. Jan 2022
  174. www.sciencedirect.com www.sciencedirect.com
    Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment
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  175. www.sciencedirect.com www.sciencedirect.com
    Presynaptic mechanisms underlying GABAB-receptor-mediated inhibition of spontaneous neurotransmitter release
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  176. www.sciencedirect.com www.sciencedirect.com
    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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  177. www.sciencedirect.com www.sciencedirect.com
    Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase
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    sciencedirect.com/science/article/pii/S2589004221016205
  178. link.springer.com link.springer.com
    Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
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  179. Nov 2021
  180. www.nature.com www.nature.com
    Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer
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  181. www.sciencedirect.com www.sciencedirect.com
    Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro
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  182. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay
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  184. www.sciencedirect.com www.sciencedirect.com
    Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
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  185. Oct 2021
  186. www.sciencedirect.com www.sciencedirect.com
    Direct conversion of adult fibroblasts into motor neurons
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    A synaptic temperature sensor for body cooling
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system
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  189. Sep 2021
  190. www.sciencedirect.com www.sciencedirect.com
    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition
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  193. Aug 2021
  194. www.sciencedirect.com www.sciencedirect.com
    A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
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  195. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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  196. www.sciencedirect.com www.sciencedirect.com
    Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases
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  197. www.sciencedirect.com www.sciencedirect.com
    A flow cytometry-based assay for serological detection of anti-spike antibodies in COVID-19 patients
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  199. www.sciencedirect.com www.sciencedirect.com
    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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      Plasmid_12253

      DOI: 10.1016/j.cell.2018.11.024

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    sciencedirect.com/science/article/pii/S0092867418315162
  200. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      Addgene_12253

      DOI: 10.1016/j.molcel.2018.11.015

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    sciencedirect.com/science/article/pii/S1097276518309857
  201. www.sciencedirect.com www.sciencedirect.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
    1
    1. scibot 07 Aug 2021
      Plasmid_12253

      DOI: 10.1016/j.cell.2016.12.036

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    sciencedirect.com/science/article/pii/S0092867416317524
  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deregulation of Exo70 Facilitates Innate and Acquired Cisplatin Resistance in Epithelial Ovarian Cancer by Promoting Cisplatin Efflux
    1
    1. scibot 05 Aug 2021
      RRID:Addgene_12253

      DOI: 10.3390/cancers13143467

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    ncbi.nlm.nih.gov/pmc/articles/PMC8304026/
  203. www.sciencedirect.com www.sciencedirect.com
    Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
    1
    1. scibot 01 Aug 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.celrep.2021.109460

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    sciencedirect.com/science/article/pii/S2211124721008834
  204. Jul 2021
  205. www.sciencedirect.com www.sciencedirect.com
    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
    1
    1. scibot 30 Jul 2021
      pRSV-REV (lentiviral helper plasmid)

      DOI: 10.1016/j.cell.2019.09.011

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    sciencedirect.com/science/article/pii/S0092867419310177
  206. www.sciencedirect.com www.sciencedirect.com
    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
    1
    1. scibot 29 Jul 2021
      Addgene12253

      DOI: 10.1016/j.ccell.2019.08.006

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    sciencedirect.com/science/article/pii/S1535610819303745
  207. www.sciencedirect.com www.sciencedirect.com
    Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion
    1
    1. scibot 29 Jul 2021
      Addgene Plasmid:12253

      DOI: 10.1016/j.celrep.2019.08.017

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    sciencedirect.com/science/article/pii/S2211124719310502
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 27 Jul 2021
      Addgene_12253

      DOI: 10.1016/j.cub.2018.08.060

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224479/
  209. link.springer.com link.springer.com
    Methods for Modulating the Pathway of NF-κB Using <IndexTerm ID="ITerm1">Short Hairpin RNA (ShRNA)</IndexTerm>
    1
    1. scibot 16 Jul 2021
      RRID:Addgene_12253

      DOI: 10.1007/978-1-0716-1669-7_6

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    link.springer.com/protocol/10.1007/978-1-0716-1669-7_6
  210. www.sciencedirect.com www.sciencedirect.com
    Active elimination of intestinal cells drives oncogenic growth in organoids
    1
    1. scibot 09 Jul 2021
      12253

      DOI: 10.1016/j.celrep.2021.109307

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    sciencedirect.com/science/article/pii/S2211124721006835
  211. www.sciencedirect.com www.sciencedirect.com
    Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit
    1
    1. scibot 07 Jul 2021
      plasmid_12253

      DOI: 10.1016/j.celrep.2021.109338

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    sciencedirect.com/science/article/pii/S2211124721007142
  212. Jun 2021
  213. www.sciencedirect.com www.sciencedirect.com
    Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion
    1
    1. scibot 15 Jun 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.xpro.2021.100603

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    sciencedirect.com/science/article/pii/S2666166721003105
  214. www.sciencedirect.com www.sciencedirect.com
    Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
    1
    1. scibot 04 Jun 2021
      Plasmid_12253

      DOI: 10.1016/j.xpro.2021.100580

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    sciencedirect.com/science/article/pii/S2666166721002872
  215. May 2021
  216. www.sciencedirect.com www.sciencedirect.com
    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
    1
    1. scibot 28 May 2021
      CAT#12253

      DOI: 10.1016/j.cell.2021.04.037

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    sciencedirect.com/science/article/pii/S0092867421005729
  217. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
    1
    1. scibot 22 May 2021
      RRID:Addgene_12253

      DOI: 10.1038/s42003-021-02104-2

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    nature.com/articles/s42003-021-02104-2
  218. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      Addgene Cat#12253

      DOI: 10.1016/j.cell.2021.04.022

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    sciencedirect.com/science/article/pii/S009286742100502X
  219. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
    1
    1. scibot 14 May 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  220. www.nature.com www.nature.com
    The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2
    1
    1. scibot 12 May 2021
      RRID:Addgene_12253

      DOI: 10.1038/s41420-021-00479-z

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    nature.com/articles/s41420-021-00479-z
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia
    1
    1. scibot 12 May 2021
      Addgene_12253

      DOI: 10.1016/j.cell.2021.04.033

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    ncbi.nlm.nih.gov/pmc/articles/PMC8064868/
  222. www.eneuro.org www.eneuro.org
    FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development
    1
    1. scibot 10 May 2021
      RRID:Addgene_12253

      DOI: 10.1523/ENEURO.0193-20.2021

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    eneuro.org/content/8/2/ENEURO.0193-20.2021
  223. www.sciencedirect.com www.sciencedirect.com
    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies
    1
    1. scibot 08 May 2021
      Addgene_12253

      DOI: 10.1016/j.neuron.2020.10.012

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    sciencedirect.com/science/article/pii/S0896627320308084
  224. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
    1
    1. scibot 07 May 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.molcel.2020.04.031

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    sciencedirect.com/science/article/pii/S1097276520302732
  225. www.sciencedirect.com www.sciencedirect.com
    Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer
    1
    1. scibot 07 May 2021
      plasmid_12253

      DOI: 10.1016/j.jconrel.2020.11.020

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    sciencedirect.com/science/article/pii/S0168365920306696
  226. www.sciencedirect.com www.sciencedirect.com
    Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1
    1
    1. scibot 05 May 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.devcel.2020.07.017

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    sciencedirect.com/science/article/pii/S153458072030592X
  227. Apr 2021
  228. www.sciencedirect.com www.sciencedirect.com
    A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form
    1
    1. scibot 28 Apr 2021
      Plasmid#12253

      DOI: 10.1016/j.chembiol.2020.09.004

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    sciencedirect.com/science/article/pii/S2451945620303767
  229. www.sciencedirect.com www.sciencedirect.com
    Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis
    1
    1. scibot 27 Apr 2021
      RRID:Addgene_12253

      DOI: 10.1016/j.cell.2021.02.048

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    sciencedirect.com/science/article/pii/S0092867421002373
  230. www.sciencedirect.com www.sciencedirect.com
    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
    1
    1. scibot 24 Apr 2021
      Addgene 12253

      DOI: 10.1016/j.cell.2020.12.025

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    sciencedirect.com/science/article/pii/S0092867420317475
  231. www.sciencedirect.com www.sciencedirect.com
    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
    1
    1. scibot 23 Apr 2021
      CAT#12253

      DOI: 10.1016/j.cell.2020.02.003

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    sciencedirect.com/science/article/pii/S0092867420301471