494 Matching Annotations
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    Inhibiting KRAS with CD47 and immune checkpoint overcomes intrinsic resistance to combined KRAS and immune checkpoint inhibitor therapy
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    sciencedirect.com/science/article/pii/S2666379125003908
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    Selective TLR ligand stimulation enhances in vivo mosquito-borne flavivirus pathogenicity
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    LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
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    sciencedirect.com/science/article/pii/S2666979X25002356
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    A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation
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    sciencedirect.com/science/article/pii/S1097276525006513
  6. Aug 2025
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    The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation
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    HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
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    QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome
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    Induction of Human Pruriceptors from Pluripotent Stem Cells via Transcription Factors
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    Aging murine peritoneal macrophages undergo female-specific remodeling driven by hormone-dependent and independent mechanisms
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    Mapping the transcriptional and epigenetic landscape of organotypic endothelial diversity in the developing and adult mouse
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    ATG7 in innate immune cells is required for host defense against nontuberculous mycobacterial pulmonary infections
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    Protocol to rapidly screen CRISPR-Cas9 gene editing outcomes in a cell population by mutating eGFP to a blue or non-fluorescent phenotype
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    DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint
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    NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
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    Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma
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    Establishment of a green fluorescent protein (GFP)-based reporter for picornaviral 3C proteases
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  24. Jul 2025
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    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure
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  45. Jun 2025
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    Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1
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    ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in non–small cell lung cancer
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    Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ubiquitylation of DDX6
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    HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
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    A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation
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    Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer
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    TFE3 fusion oncoprotein condensates drive transcriptional reprogramming and cancer progression in translocation renal cell carcinoma
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    T-bet overexpression enhances CAR T cell effector functions and antigen sensitivity
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    Proteomics Analysis of the TDP-43 Interactome in Cellular Models of ALS Pathogenesis
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    Overcoming antigen loss in CAR T therapy with Vγ9Vδ2 CAR T-cells
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    Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer
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  179. Oct 2024
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  181. www.sciencedirect.com www.sciencedirect.com
    Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs
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  182. www.biorxiv.org www.biorxiv.org
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    biorxiv.org/content/10.1101/2024.09.23.614644v1
  183. Sep 2024
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EFFECTS OF ARYL HYDROCARBON RECEPTOR LIGAND TCDD ON HUMAN TROPHOBLAST CELL DEVELOPMENT
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388022/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD8α Structural Domains Enhance GUCY2C CAR-T Cell Efficacy
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  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ligand requirements for immunoreceptor triggering
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteasome and Cul3-Dependent Protein Ubiquitination Is Required for Gli Protein-Mediated Activation of Gene Expression in the Hedgehog Pathway
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploring the transcriptional cooperation between RUNX2 and its associated elncRNA RAIN
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11410950/
  198. www.sciencedirect.com www.sciencedirect.com
    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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  200. www.sciencedirect.com www.sciencedirect.com
    Targeting heterozygous dominant negative variant of KCNA2 using Gapmer antisense oligonucleotides (ASO) for the treatment of drug-resistant epilepsy
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A naturally occurring 22-amino acid fragment of human hemoglobin A inhibits autophagy and HIV-1
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    Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology
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  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer’s disease
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  205. www.biorxiv.org www.biorxiv.org
    Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells
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    biorxiv.org/content/10.1101/2024.07.20.604396v2
  206. Aug 2024
  207. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19
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    ncbi.nlm.nih.gov/pmc/articles/PMC11256170/
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways
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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257948/
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of DNA minicircles for delivery of adenine and cytosine base editors using activatable gene on “GO” reporter imaging systems
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