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    TCF19 promotes cell proliferation and tumor formation in lung cancer by activating the Raf/MEK/ERK signaling pathway
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      pMD2. G

      DOI: 10.1016/j.tranon.2024.101978

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    ncbi.nlm.nih.gov/pmc/articles/PMC11088346/
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    TFPI from erythroblasts drives heme production in central macrophages promoting erythropoiesis in polycythemia
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      pMD2.G

      DOI: 10.1038/s41467-024-48328-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11087540/
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    FBXO22 is a potential therapeutic target for recurrent chondrosarcoma
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      12259

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    Cyclin‐dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration‐resistant prostate cancer
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      12259

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    Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line
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      12,259

      DOI: 10.1186/s12860-024-00511-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11089686/
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    CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1
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    1. scibot 19 May 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11091187/
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    PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling
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      pMD2.G

      DOI: 10.1186/s13046-024-03062-3

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    Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
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    NPEPPS Is a Druggable Driver of Platinum Resistance
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      pMD2.G

      DOI: 10.1158/0008-5472.CAN-23-1976

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    Urolithin A Hijacks ERK1/2‐ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity
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      12259

      DOI: 10.1002/advs.202310065

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    Endocardial HDAC3 is required for myocardial trabeculation
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      12259

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    Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
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      12259

      DOI: 10.1038/s42003-024-06288-1

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    Shared and distinct mechanisms of UBA1 inactivation across different diseases
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      Addgene_12259

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    Nanobody-based CAR NK cells for possible immunotherapy of MICA+ tumors
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    1. scibot 19 May 2024
      RRID:Addgene_12259

      DOI: 10.1093/pnasnexus/pgae184

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      RRID:Addgene_12259

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    CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair
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      Addgene_12

      DOI: 10.1186/s12943-024-02021-y

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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    1. scibot 17 May 2024
      AddgeneCat# 12259

      DOI: 10.1016/j.molcel.2024.04.009

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    Large donor CRISPR for whole-CDS replacement of cell adhesion molecule LRRTM2
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    1. scibot 17 May 2024
      RRID:Addgene_12259

      DOI: 10.1101/2024.05.03.592283

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    mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism
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      RRID:Addgene_12259

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    Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes
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    1. scibot 17 May 2024
      Addgene_12259

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    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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      Addgene_12259

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    sciencedirect.com/science/article/pii/S1097276524003290
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    linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability
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    1. scibot 16 May 2024
      Addgene12259

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    Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation
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    1. scibot 16 May 2024
      RRID:Addgene_12259

      DOI: 10.1101/2024.02.29.582681

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    CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity
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    1. scibot 16 May 2024
      AddgeneCat# 12259

      DOI: 10.1016/j.immuni.2024.04.017

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    sciencedirect.com/science/article/pii/S107476132400222X
  25. cancerci.biomedcentral.com cancerci.biomedcentral.com
    HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer
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      RRID: Addgene_12259

      DOI: 10.1186/s12935-024-03364-8

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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
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      Addgene_12259

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    Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
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      RRID:Addgene_12259

      DOI: 10.1186/s13293-024-00618-y

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    Bottom-up reconstruction of functional Death Domain Signalosomes reveals a requirement for polymer stability and avidity
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      plasmid_12259

      DOI: 10.1101/2024.05.08.593169

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    Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
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      Addgene_12259

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    Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
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      Addgene_12259

      DOI: 10.1016/j.celrep.2021.108887

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    sciencedirect.com/science/article/pii/S2211124721002011
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    Engineering lentivirus envelope VSV-G for liver targeted delivery of IDOL-shRNA to ameliorate hypercholesterolemia and atherosclerosis
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      pMD2.G

      DOI: 10.1016/j.omtn.2024.102115

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    sciencedirect.com/science/article/pii/S2162253124000027
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    Imaging CAR-NK cells targeted to HER2 ovarian cancer with human sodium-iodide symporter-based positron emission tomography
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    1. scibot 15 May 2024
      RRID:Addgene_12259

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    Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
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      RRID:Addgene_12259

      DOI: 10.1016/j.stem.2024.04.016

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  34. May 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets
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      12259

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription
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      12259

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner
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      12259

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic context– and H2AK119 ubiquitination–dependent inheritance of human Polycomb silencing
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      12259

      DOI: 10.1126/sciadv.adl4529

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter
    1
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      12259

      DOI: 10.1093/nar/gkae240

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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes
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      12259

      DOI: 10.1128/mbio.03429-23

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IL-6 signaling pathway contributes critically to the immunomodulatory mechanism of human decidua-derived mesenchymal stromal cells
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  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The phosphatidylinositol-5′ phosphatase synaptojanin1 limits integrin-mediated invasion of Staphylococcus aureus
    1
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10986543/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SP2509, a specific antagonist of LSD1, exhibits antiviral properties against Porcine epidemic diarrhea virus
    1
    1. scibot 12 May 2024
      pMD2.G

      DOI: 10.1186/s12917-024-04052-5

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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness
    1
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      12259

      DOI: 10.3390/ijms25094795

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD133 Stimulates Cell Proliferation via the Upregulation of Amphiregulin in Melanoma
    1
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer
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  49. 52.53.155.43 52.53.155.43
    2024.02.09.579580v1.full-html.html
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  50. www.cell.com www.cell.com
    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
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  51. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
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  52. www.sciencedirect.com www.sciencedirect.com
    Activating innate immune responses repolarizes hPSC-derived CAR macrophages to improve anti-tumor activity
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  53. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell competition promotes metastatic intestinal cancer through a multistage process
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  55. www.sciencedirect.com www.sciencedirect.com
    An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins
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  56. www.mdpi.com www.mdpi.com
    The Disassociation of A3G-Related HIV-1 cDNA G-to-A Hypermutation to Viral Infectivity
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLEC4D as a Novel Prognostic Marker Boosts the Proliferation and Migration of Gastric Cancer via the NF-κB/AKT Signaling Pathway
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  58. www.sciencedirect.com www.sciencedirect.com
    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circadian coupling of mitochondria in a deep-diving mammal
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of nuclear receptor co‑activator 7 protein is associated with poor prognosis of breast cancer
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The epigenetic regulators EP300/CREBBP represent promising therapeutic targets in MLL-rearranged acute myeloid leukemia
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Production of Recombinant VSVs with Confirmation of Biological Activity
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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  72. www.sciencedirect.com www.sciencedirect.com
    The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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  74. www.biorxiv.org www.biorxiv.org
    The RNA polymerase II general transcription factor TFIIB is a target for transcriptome control during cellular stress and viral infection
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  75. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    BAG3 regulates cilia homeostasis of glioblastoma via its WW domain
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  76. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza Virus Reduces Ubiquitin E3 Ligase MARCH10 Expression to Decrease Ciliary Beat Frequency
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  79. www.sciencedirect.com www.sciencedirect.com
    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
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    The Mediator Med23 controls a transcriptional switch for muscle stem cell proliferation and differentiation in muscle regeneration
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  82. Apr 2024
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CK2α-mediated phosphorylation of GRP94 facilitates the metastatic cascade in triple-negative breast cancer
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ribosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis
    1
    1. scibot 30 Apr 2024
      pMD2.G

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic transcription factor binding site selection is edited by the chromatin remodeling factor CHD4
    1
    1. scibot 30 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039999/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer
    1
    1. scibot 30 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer
    1
    1. scibot 30 Apr 2024
      12259

      DOI: 10.1038/s42003-024-06190-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
    1. scibot 30 Apr 2024
      RRID:Addgene_12259

      DOI: 10.1101/2024.04.02.587836

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stepwise Stiffening/Softening of and Cell Recovery from Reversibly Formulated Hydrogel Double Networks
    1
    1. scibot 30 Apr 2024
      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030224/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Culture substrate stiffness impacts human myoblast contractility-dependent proliferation and nuclear envelope wrinkling
    1
    1. scibot 30 Apr 2024
      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11033523/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Missing WD40 Repeats in ATG16L1 Delays Canonical Autophagy and Inhibits Noncanonical Autophagy
    1
    1. scibot 29 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11050548/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and Characterization of SV40 T-Antigen Immortalized Porcine Muscle Satellite Cell
    1
    1. scibot 29 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11049531/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial
    1
    1. scibot 29 Apr 2024
      12,259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11048007/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation
    1
    1. scibot 29 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11047997/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C
    1
    1. scibot 29 Apr 2024
      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046299/
  98. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
    1
    1. scibot 26 Apr 2024
      AddGene12259

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    sciencedirect.com/science/article/pii/S2666379124001927
  99. www.sciencedirect.com www.sciencedirect.com
    Functional sensory circuits built from neurons of two species
    2
    1. scibot 26 Apr 2024
      Addgene Cat# 12259

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    sciencedirect.com/science/article/pii/S0092867424003581
  100. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    1
    1. scibot 26 Apr 2024
      Addgene, Cat# 12259

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    sciencedirect.com/science/article/pii/S0092867424003131
  101. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
    1
    1. scibot 25 Apr 2024
      RRID:Addgene_12259

      DOI: 10.1073/pnas.2314695121

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    pnas.org/doi/abs/10.1073/pnas.2314695121
  102. www.sciencedirect.com www.sciencedirect.com
    Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices
    1
    1. scibot 25 Apr 2024
      RRID:Addgene_12259

      DOI: 10.1016/j.cdev.2024.203923

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    sciencedirect.com/science/article/pii/S266729012400024X
  103. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
    1
    1. scibot 24 Apr 2024
      AddgeneCat# 12259

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    sciencedirect.com/science/article/pii/S0092867424003556
  104. www.sciencedirect.com www.sciencedirect.com
    Protocol for efficient CRISPR-Cas9-mediated fluorescent tag knockin in hard-to-transfect erythroid cell lines
    1
    1. scibot 23 Apr 2024
      AddgeneCat# 12259

      DOI: 10.1016/j.xpro.2024.103016

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    sciencedirect.com/science/article/pii/S2666166724001813
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patient-derived response estimates from zero-passage organoids of luminal breast cancer
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1101/2024.03.24.586432

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996455/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Scribble/SGEF/Dlg1 complex regulates the stability of apical junctions in epithelial cells
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1101/2024.03.26.586884

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996629/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1101/2024.03.21.585809

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996540/
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus 2 hijacks CMA-mediated lipolysis through upregulation of small GTPase RAB18
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1371/journal.ppat.1012123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014436/
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1038/s41467-024-47449-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation
    1
    1. scibot 23 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014252/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An optogenetic method for the controlled release of single molecules
    1
    1. scibot 23 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009104/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmented ERO1α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11
    1
    1. scibot 23 Apr 2024
      pMD2.G

      DOI: 10.1186/s13046-024-03039-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11015652/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An EBV-related CD4 TCR immunotherapy inhibits tumor growth in an HLA-DP5+ nasopharyngeal cancer mouse model
    1
    1. scibot 23 Apr 2024
      pMD2G

      DOI: 10.1172/JCI172092

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014665/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transmembrane Protein TMEM230, Regulator of Glial Cell Vascular Mimicry and Endothelial Cell Angiogenesis in High-Grade Heterogeneous Infiltrating Gliomas and Glioblastoma
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.3390/ijms25073967

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011566/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia through Advanced Non-Invasive Apoptosis Detection Sensor Version 2 Detection
    1
    1. scibot 23 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011921/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy between BRD9- and IKZF3-Targeting as a Therapeutic Strategy for Multiple Myeloma
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.3390/cancers16071319

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    ncbi.nlm.nih.gov/pmc/articles/PMC11010819/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Photophysics-informed two-photon voltage imaging using FRET-opsin voltage indicators
    1
    1. scibot 23 Apr 2024
      12259

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-147b mediated suppression of DUSP8 promotes lung cancer progression
    1
    1. scibot 23 Apr 2024
      pMD2.G

      DOI: 10.1038/s41388-024-02969-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014796/
  119. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1038/s44319-024-00110-z

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    embopress.org/doi/full/10.1038/s44319-024-00110-z
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA‐binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA
    1
    1. scibot 23 Apr 2024
      PMD2.g

      DOI: 10.1002/cam4.7129

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.3389/fmolb.2023.1295507

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    ncbi.nlm.nih.gov/pmc/articles/PMC11020096/
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H2A variant H2A.B is enriched in transcriptionally active and replicating HSV-1 lytic chromatin
    1
    1. scibot 23 Apr 2024
      pMD2.G

      DOI: 10.1128/jvi.02015-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC11019955/
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage
    1
    1. scibot 23 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11024517/
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1038/s41556-024-01386-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021197/
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers
    1
    1. scibot 23 Apr 2024
      12259

      DOI: 10.1038/s41419-024-06654-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11024179/
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinome‐Wide Synthetic Lethal Screen Identifies PANK4 as a Modulator of Temozolomide Resistance in Glioblastoma
    1
    1. scibot 23 Apr 2024
      12259

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5
    1
    1. scibot 23 Apr 2024
      12,259

      DOI: 10.1186/s13059-024-03242-6

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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood–brain barrier integrity and cognitive function in uremic encephalopathy
    1
    1. scibot 23 Apr 2024
      12,259

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  129. 52.53.155.43 52.53.155.43
    Ferritin heavy chain supports stability and function of the regulatory T cell lineage
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    1. scibot 19 Apr 2024
      AddgeneCat#12259

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  130. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
    2
    1. scibot 19 Apr 2024
      RRID:Addgene_12259

      DOI: 10.1158/0008-5472.CAN-23-0910

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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  131. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  132. aacrjournals.org aacrjournals.org
    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  133. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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  134. www.biorxiv.org www.biorxiv.org
    Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes
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  135. aacrjournals.org aacrjournals.org
    Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors
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  136. www.sciencedirect.com www.sciencedirect.com
    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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  137. www.sciencedirect.com www.sciencedirect.com
    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5
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    1. scibot 18 Apr 2024
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  139. www.sciencedirect.com www.sciencedirect.com
    SHIP inhibition mediates select TREM2-induced microglial functions
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      Addgene #12259

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  140. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    13C-SpaceM: Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A temperature-inducible protein module for control of mammalian cell fate
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    1. scibot 15 Apr 2024
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-linear transcriptional responses to gradual modulation of transcription factor dosage
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    1. scibot 15 Apr 2024
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PLEKHM2 deficiency induces impaired mitochondrial clearance and elevated ROS levels in human iPSC-derived cardiomyocytes
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      12259

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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    1. scibot 15 Apr 2024
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network
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      12,259

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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nanoparticles for RNA Therapeutics: Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery
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    1. scibot 15 Apr 2024
      12259

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
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      12259

      DOI: 10.7554/eLife.92755

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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
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      12259

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipose tissue peroxisomal lipid synthesis orchestrates obesity and insulin resistance through LXR-dependent lipogenesis
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      12259

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A
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      pMD2.G

      DOI: 10.1128/jvi.01944-23

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 Spike is a virulence determinant and plays a major role on the attenuated phenotype of Omicron virus in a feline model of infection
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      12259

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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
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      12259

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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of Wnt5a promoted the protective effect of mesenchymal stem cells on Lipopolysaccharide-induced endothelial cell injury via activating PI3K/AKT signaling pathway
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
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      pMD.2 G

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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATF3-CBS signaling axis coordinates ferroptosis and tumorigenesis in colorectal cancer
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting autophagy overcomes cancer‐intrinsic resistance to CAR‐T immunotherapy in B‐cell malignancies
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the insulin receptor by insulin-like growth factor 2
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and utilization of endostatin‐sensitive cell lines for assessing the biological activity of endostatin
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons
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      pMD2.G

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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated in vivo functional screens and multi-omics analyses identify α-2,3-sialylation as essential for melanoma maintenance
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN loss in glioma cell lines leads to increased extracellular vesicles biogenesis and PD-L1 cargo in a PI3K-dependent manner
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMARCAL1 ubiquitylation controls its association with RPA-coated ssDNA and promotes replication fork stability
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
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    1. scibot 15 Apr 2024
      addgene_12259

      DOI: 10.7554/eLife.90522

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    ncbi.nlm.nih.gov/pmc/articles/PMC10954306/
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
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    1. scibot 15 Apr 2024
      Addgene_12259

      DOI: 10.1091/mbc.E23-08-0336

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881158/
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation
    1
    1. scibot 15 Apr 2024
      plasmid_12259

      DOI: 10.1084/jem.20231200

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    ncbi.nlm.nih.gov/pmc/articles/PMC10966137/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CROPseq-multi: a versatile solution for multiplexed perturbation and decoding in pooled CRISPR screens
    1
    1. scibot 15 Apr 2024
      Addgene_12259

      DOI: 10.1101/2024.03.17.585235

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979941/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TM4SF19-mediated control of lysosomal activity in macrophages contributes to obesity-induced inflammation and metabolic dysfunction
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    1. scibot 14 Apr 2024
      pMD2.G

      DOI: 10.1038/s41467-024-47108-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10981689/
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrated framework for prognosis prediction and drug response modeling in colorectal liver metastasis drug discovery
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    1. scibot 14 Apr 2024
      pMD2.G

      DOI: 10.1186/s12967-024-05127-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10981831/
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K1 regulates female reproductive tract development
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    1. scibot 14 Apr 2024
      #12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10985838/
  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    1. scibot 14 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed dynamic control of temperature to probe and observe mammalian cells
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    1. scibot 14 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983861/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The P124A mutation of SRP14 alters its migration on SDS-PAGE without impacting its function: Mutations in the A-rich tail of SRP14 lead to altered migration on SDS-PAGE
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    1. scibot 14 Apr 2024
      pMD2.G

      DOI: 10.3724/abbs.2024004

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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer
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    1. scibot 14 Apr 2024
      12259

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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
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    1. scibot 14 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional genetics reveals modulators of anti-microtubule drug sensitivity
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    1. scibot 14 Apr 2024
      Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979949/
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screens decode cancer cell pathways that trigger γδ T cell detection
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      plasmid_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC11003766/
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts
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    1. scibot 13 Apr 2024
      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993186/
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response
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      12259

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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The subcommissural organ regulates brain development via secreted peptides
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    1. scibot 13 Apr 2024
      12259

      DOI: 10.1101/2024.03.30.587415

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996762/
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
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      pMD2.D

      DOI: 10.1186/s13046-024-03020-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11008035/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders
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      12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996091/
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GGT5 facilitates migration and invasion through the induction of epithelial–mesenchymal transformation in gastric cancer
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      12259

      DOI: 10.1186/s12920-024-01856-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10998378/
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GHITM regulates malignant phenotype and sensitivity to PD‐1 blockade of renal cancer cells via Notch signalling
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    1. scibot 13 Apr 2024
      pMD2.G

      DOI: 10.1111/jcmm.18290

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000813/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC38A2 promotes cell proliferation and invasion by promoting glutamine metabolism in adenomyosis
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    1. scibot 13 Apr 2024
      pMD2G

      DOI: 10.3892/etm.2024.12506

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000443/
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA RAD51-AS1 promotes the tumorigenesis of ovarian cancer by elevating EIF5A2 expression
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      pMD2G

      DOI: 10.1007/s00432-024-05671-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10999386/
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux
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      12259

      DOI: 10.1016/j.bbrep.2024.101705

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    ncbi.nlm.nih.gov/pmc/articles/PMC11001778/
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted Protein Degradation through Recruitment of the CUL4A Complex Adaptor Protein DDB1
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      12,259

      DOI: 10.1021/acschembio.3c00487

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    ncbi.nlm.nih.gov/pmc/articles/PMC11003717/
  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology
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    1. scibot 13 Apr 2024
      pMD2.G

      DOI: 10.1128/mbio.02623-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC11005406/
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
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    1. scibot 13 Apr 2024
      Addgene_12259

      DOI: 10.1038/s41541-024-00854-8

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