1,588 Matching Annotations
  1. Jan 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma
    1
    1. scibot 15 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1158/2159-8290.CD-22-0427

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827116/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
    1
    1. scibot 15 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  4. journals.lww.com journals.lww.com
    Oncogenic BRAFV600E induces microglial proliferation... : Neural Regeneration Research
    1
    1. scibot 14 Jan 2023
      RRID:Addgene_12259

      DOI: 10.4103/1673-5374.361516

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    journals.lww.com/nrronline/Fulltext/2023/07000/Oncogenic_BRAFV600E_induces_microglial.38.aspx
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute COG inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra-Golgi recycling vesicles
    1
    1. scibot 14 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1111/tra.12876

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    onlinelibrary.wiley.com/doi/10.1111/tra.12876
  6. link.springer.com link.springer.com
    Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
    1
    1. scibot 14 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1007/s00125-022-05856-6

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    link.springer.com/article/10.1007/s00125-022-05856-6
  7. rupress.org rupress.org
    Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion
    1
    1. scibot 12 Jan 2023
      plasmid_12259

      DOI: 10.1083/jcb.202204100

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    rupress.org/jcb/article/222/2/e202204100/213712/Fibroblasts-secrete-fibronectin-under-lamellipodia
  8. www.sciencedirect.com www.sciencedirect.com
    DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2022.111986

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    sciencedirect.com/science/article/pii/S2211124722018903
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistancePARP7 inhibitor CRISPR screen
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1158/1535-7163.MCT-21-0841

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    ncbi.nlm.nih.gov/pmc/articles/PMC9769698/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses
    1
    1. scibot 11 Jan 2023
      Plasmid #12259 (Addgene)

      DOI: 10.1016/j.isci.2022.105887

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    ncbi.nlm.nih.gov/pmc/articles/PMC9794394/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells
    1
    1. scibot 11 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.xpro.2022.101992

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    ncbi.nlm.nih.gov/pmc/articles/PMC9826815/
  12. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
    1
    1. scibot 11 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2022.12.016

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    sciencedirect.com/science/article/pii/S009286742201529X
  13. www.sciencedirect.com www.sciencedirect.com
    Resurrection of endogenous retroviruses during aging reinforces senescence
    1
    1. scibot 07 Jan 2023
      plasmid_12259

      DOI: 10.1016/j.cell.2022.12.017

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    sciencedirect.com/science/article/pii/S0092867422015306
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
    1
    1. scibot 07 Jan 2023
      Addgene_12259

      DOI: 10.1158/2159-8290.CD-21-0646

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    ncbi.nlm.nih.gov/pmc/articles/PMC9453853/
  15. www.sciencedirect.com www.sciencedirect.com
    Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis
    1
    1. scibot 06 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.joca.2022.12.010

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    sciencedirect.com/science/article/pii/S1063458423000018
  16. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
    1
    1. scibot 06 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.stem.2022.12.006

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    sciencedirect.com/science/article/pii/S1934590922004908
  17. www.cell.com www.cell.com
    Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
    1
    1. scibot 02 Jan 2023
      RRID:Addgene_12259

      DOI: 10.1016/j.ccell.2022.12.003

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    cell.com/cancer-cell/fulltext/S1535-6108(22)00589-X
  18. Dec 2022
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
    1
    1. scibot 31 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1128/mbio.02446-22

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    ncbi.nlm.nih.gov/pmc/articles/PMC9765453/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
    1
    1. scibot 31 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1158/2767-9764.crc-22-0262

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    ncbi.nlm.nih.gov/pmc/articles/PMC9770512/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Virus-like particle – mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection
    1
    1. scibot 30 Dec 2022
      plasmid_12259

      DOI: 10.3389/fcimb.2022.1079926

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    ncbi.nlm.nih.gov/pmc/articles/PMC9795031/
  22. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
    1
    1. scibot 29 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1007/s12035-022-03153-2

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    link.springer.com/article/10.1007/s12035-022-03153-2
  23. aacrjournals.org aacrjournals.org
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
    1
    1. scibot 24 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1158/2767-9764.CRC-22-0262

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    aacrjournals.org/cancerrescommun/article/2/12/1545/711358/IL1-Expression-Driven-by-Androgen-Receptor-Absence
  24. aacrjournals.org aacrjournals.org
    Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing
    1
    1. scibot 24 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1158/0008-5472.CAN-21-2519

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    aacrjournals.org/cancerres/article/82/17/3002/708290/Efficient-Correction-of-Oncogenic-KRAS-and-TP53
  25. www.sciencedirect.com www.sciencedirect.com
    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury
    1
    1. scibot 24 Dec 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111848

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    sciencedirect.com/science/article/pii/S2211124722017405
  26. www.sciencedirect.com www.sciencedirect.com
    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
    1
    1. scibot 20 Dec 2022
      Addgene_12259

      DOI: 10.1016/j.devcel.2022.11.015

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    sciencedirect.com/science/article/pii/S1534580722008152
  27. link.springer.com link.springer.com
    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
    1
    1. scibot 20 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1007/s00018-022-04638-y

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    link.springer.com/article/10.1007/s00018-022-04638-y
  28. www.sciencedirect.com www.sciencedirect.com
    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
    1
    1. scibot 18 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2022.111819

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    sciencedirect.com/science/article/pii/S2211124722017119
  29. www.sciencedirect.com www.sciencedirect.com
    Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection
    1
    1. scibot 18 Dec 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111817

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    sciencedirect.com/science/article/pii/S2211124722017090
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and Analysis of hTERT-RPE1 VPS54 Knock-Out and Rescued Cell Lines
    2
    1. scibot 17 Dec 2022
      plasmid_12259

      DOI: 10.1007/978-1-0716-2639-9_22

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    2. scibot 17 Dec 2022
      RRID:Addgene_12

      DOI: 10.1007/978-1-0716-2639-9_22

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    ncbi.nlm.nih.gov/pmc/articles/PMC10026839/
  31. link.springer.com link.springer.com
    Rapid COG Depletion in Mammalian Cell by Auxin-Inducible Degradation System
    1
    1. scibot 17 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1007/978-1-0716-2639-9_23

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    link.springer.com/protocol/10.1007/978-1-0716-2639-9_23
  32. www.sciencedirect.com www.sciencedirect.com
    Engineered cell entry links receptor biology with single-cell genomics
    1
    1. scibot 17 Dec 2022
      addgene_12259

      DOI: 10.1016/j.cell.2022.11.016

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    sciencedirect.com/science/article/pii/S009286742201460X
  33. www.sciencedirect.com www.sciencedirect.com
    A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates
    1
    1. scibot 11 Dec 2022
      plasmid_12259

      DOI: 10.1016/j.cell.2022.11.005

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    sciencedirect.com/science/article/pii/S0092867422014155
  34. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    2
    1. scibot 08 Dec 2022
      12259

      DOI: 10.1016/j.celrep.2022.111653

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    2. scibot 08 Dec 2022
      plasmid_12259

      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  35. www.sciencedirect.com www.sciencedirect.com
    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
    1
    1. scibot 08 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2022.11.010

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    sciencedirect.com/science/article/pii/S1097276522010991
  36. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
    1
    1. scibot 03 Dec 2022
      RRID:Addgene_12259

      DOI: 10.1158/2159-8290.CD-22-0287

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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  37. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    1
    1. scibot 02 Dec 2022
      RRID:Addgene_12259

      DOI: 10.15252/emmm.202115631

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    embopress.org/doi/10.15252/emmm.202115631
  38. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111727

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    sciencedirect.com/science/article/pii/S2211124722016059
  39. www.sciencedirect.com www.sciencedirect.com
    BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
    1
    1. scibot 01 Dec 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111728

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    sciencedirect.com/science/article/pii/S2211124722016060
  40. Nov 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
    1
    1. scibot 24 Nov 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111675

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    sciencedirect.com/science/article/pii/S2211124722015492
  42. www.sciencedirect.com www.sciencedirect.com
    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
    1
    1. scibot 24 Nov 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.111678

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    sciencedirect.com/science/article/pii/S2211124722015522
  43. 52.53.155.43 52.53.155.43
    Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis
    1
    1. scibot 22 Nov 2022
      plasmid_12259

      DOI: 10.1093/hmg/ddac235

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    52.53.155.43/cc79e40c92dade70c5729b9199717becabfd0bfe/ddac235-html.html
  44. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
    1
    1. scibot 22 Nov 2022
      RRID:Addgene_12259

      DOI: 10.1158/1078-0432.CCR-22-1357

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
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    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
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    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
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    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
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    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
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    The phenotypic landscape of essential human genes
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    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
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    Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
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    Multiphase coalescence mediates Hippo pathway activation
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    Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector
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  60. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
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  61. www.nature.com www.nature.com
    HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
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  62. www.nature.com www.nature.com
    HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
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  63. Oct 2022
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lentiviral vector mediated gene therapy for type I Dent disease effectively ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice
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  66. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Imaging Inflammasome Activation in Microglia
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    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments
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  70. journals.asm.org journals.asm.org
    Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi’s Sarcoma-Associated Herpesvirus Infection
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    The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies
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    Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
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    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
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    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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  75. link.springer.com link.springer.com
    Generation of a bovine cell line for gene engineering using an HIV-1-based lentiviral vector
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    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
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    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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    Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments
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  82. Sep 2022
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    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
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    Opto-katanin, an optogenetic tool for localized, microtubule disassembly
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    A screening-compatible live cell fluorescence resonance energy transfer-based assay for modulation of Rho GTPase activity
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    Determining glioma cell invasion and proliferation in ex vivo organotypic mouse brain slices using whole-mount immunostaining and tissue clearing
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  87. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
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    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
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    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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    Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation
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    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
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    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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    Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells
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    SerpinB3 drives cancer stem cell survival in glioblastoma
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    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
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    Human coronaviruses disassemble processing bodies
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    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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    Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains
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    Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine
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    CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer
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    Targeting interleukin 4 receptor alpha on tumor-associated macrophages reduces the pro-tumor macrophage phenotype
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    METTL14-dependent m6A modification controls iNKT cell development and function
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    Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
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    A CRISPR-Cas12a-based diagnostic method for multiple genotypes of severe fever with thrombocytopenia syndrome virus
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    EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity
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    FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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  124. Jul 2022
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    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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  128. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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  133. www.medrxiv.org www.medrxiv.org
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  140. 52.53.155.43 52.53.155.43
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes
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  153. www.sciencedirect.com www.sciencedirect.com
    Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs
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    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
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    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  156. May 2022
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    Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation
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    DDX41 is required for cGAS-STING activation against DNA virus infection
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
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    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
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  168. aacrjournals.org aacrjournals.org
    Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma
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    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
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    A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
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    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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  172. www.nature.com www.nature.com
    Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    SETD4-mediated KU70 methylation suppresses apoptosis
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    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
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    1. scibot 11 May 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.celrep.2022.110792

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    sciencedirect.com/science/article/pii/S2211124722005599
  176. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
    1
    1. scibot 11 May 2022
      Addgene: #12259

      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  177. www.sciencedirect.com www.sciencedirect.com
    Synthetic Carbohydrate Binding Agents neutralize SARS-CoV-2 by inhibiting binding of the spike protein to ACE2.
    2
    1. scibot 10 May 2022
      Addgene_12259

      DOI: 10.1016/j.isci.2022.104239

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    2. scibot 10 May 2022
      Addgene_12259

      DOI: 10.1016/j.isci.2022.104239

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    sciencedirect.com/science/article/pii/S2589004222005090
  178. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
    1
    1. scibot 10 May 2022
      Plasmid_12259

      DOI: 10.1038/s41420-022-01044-y

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    nature.com/articles/s41420-022-01044-y
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
    1
    1. scibot 05 May 2022
      RRID:Addgene_12259

      DOI: 10.1158/1541-7786.MCR-20-0753

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    ncbi.nlm.nih.gov/pmc/articles/PMC8568653/
  180. www.sciencedirect.com www.sciencedirect.com
    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
    1
    1. scibot 04 May 2022
      Addgene_12259

      DOI: 10.1016/j.cell.2022.04.005

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    sciencedirect.com/science/article/pii/S0092867422004433
  181. Apr 2022
  182. www.nature.com www.nature.com
    TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
    1
    1. scibot 27 Apr 2022
      plasmid_12259

      DOI: 10.1038/s41467-022-29790-8

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    nature.com/articles/s41467-022-29790-8
  183. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
    1
    1. scibot 23 Apr 2022
      RRID: Addgene_12259

      DOI: 10.1038/s41392-022-00946-8

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    nature.com/articles/s41392-022-00946-8
  184. www.sciencedirect.com www.sciencedirect.com
    Establishing transgenic murine esophageal organoids
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    1. scibot 22 Apr 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.xpro.2022.101317

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    sciencedirect.com/science/article/pii/S2666166722001976
  185. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
    1
    1. scibot 22 Apr 2022
      plasmid_12259

      DOI: 10.1158/2326-6066.CIR-21-0806

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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
    1
    1. scibot 22 Apr 2022
      plasmid_12259

      DOI: 10.3389/fonc.2022.766794

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    ncbi.nlm.nih.gov/pmc/articles/PMC9015667/
  187. www.sciencedirect.com www.sciencedirect.com
    In vitro and in vivo assay of the ER lipid scramblase TMEM41B
    1
    1. scibot 21 Apr 2022
      Addgene Cat# 12259

      DOI: 10.1016/j.xpro.2022.101333

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    sciencedirect.com/science/article/pii/S2666166722002131
  188. www.sciencedirect.com www.sciencedirect.com
    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
    2
    1. scibot 21 Apr 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.cmet.2022.03.012

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    2. scibot 21 Apr 2022
      Addgene_12259

      DOI: 10.1016/j.cmet.2022.03.012

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    sciencedirect.com/science/article/pii/S1550413122001267
  189. www.sciencedirect.com www.sciencedirect.com
    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
    1
    1. scibot 21 Apr 2022
      Addgene#12259

      DOI: 10.1016/j.molcel.2022.03.031

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    sciencedirect.com/science/article/pii/S1097276522002696
  190. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
      Plasmid_12259

      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  191. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
    1
    1. scibot 20 Apr 2022
      AddgeneCat. # 12259

      DOI: 10.1016/j.celrep.2022.110696

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    sciencedirect.com/science/article/pii/S2211124722004545
  192. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
    1
    1. scibot 20 Apr 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.celrep.2022.110692

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    sciencedirect.com/science/article/pii/S2211124722004508
  193. www.sciencedirect.com www.sciencedirect.com
    Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
    1
    1. scibot 19 Apr 2022
      Addgene_12259

      DOI: 10.1016/j.celrep.2022.110675

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    sciencedirect.com/science/article/pii/S2211124722004272
  194. www.sciencedirect.com www.sciencedirect.com
    Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling
    1
    1. scibot 15 Apr 2022
      Addgene (via Didier Trono Lab)12259

      DOI: 10.1016/j.celrep.2022.110690

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    sciencedirect.com/science/article/pii/S221112472200448X
  195. www.sciencedirect.com www.sciencedirect.com
    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
    1
    1. scibot 15 Apr 2022
      AddgeneCat#12259

      DOI: 10.1016/j.celrep.2022.110670

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    sciencedirect.com/science/article/pii/S2211124722004223
  196. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    2
    1. scibot 15 Apr 2022
      RRID: Addgene_12259

      DOI: 10.1016/j.ccell.2022.03.008

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    2. scibot 15 Apr 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.ccell.2022.03.008

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    sciencedirect.com/science/article/pii/S1535610822001234
  197. www.sciencedirect.com www.sciencedirect.com
    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
    1
    1. scibot 14 Apr 2022
      Addgene #12259

      DOI: 10.1016/j.celrep.2022.110673

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    sciencedirect.com/science/article/pii/S2211124722004259
  198. www.sciencedirect.com www.sciencedirect.com
    Rapid establishment of human colonic organoid knockout lines
    1
    1. scibot 14 Apr 2022
      Addgene #12259

      DOI: 10.1016/j.xpro.2022.101308

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    sciencedirect.com/science/article/pii/S2666166722001885
  199. www.sciencedirect.com www.sciencedirect.com
    Brown adipose tissue involution associated with progressive restriction in progenitor competence
    1
    1. scibot 14 Apr 2022
      Addgene#12259

      DOI: 10.1016/j.celrep.2022.110575

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    sciencedirect.com/science/article/pii/S2211124722003199
  200. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
    1
    1. scibot 13 Apr 2022
      Addgene Plasmid #12259

      DOI: 10.1016/j.ccell.2022.03.006

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    sciencedirect.com/science/article/pii/S1535610822001210
  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
    1
    1. scibot 13 Apr 2022
      RRID:Addgene_12259

      DOI: 10.3389/fgeed.2022.803375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8995503/