1,588 Matching Annotations
  1. Apr 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
    1
    1. scibot 07 Apr 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.celrep.2022.110637

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    sciencedirect.com/science/article/pii/S2211124722003898
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    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
    1
    1. scibot 07 Apr 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.molcel.2022.03.018

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    sciencedirect.com/science/article/pii/S1097276522002568
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    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
    1
    1. scibot 07 Apr 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.molcel.2022.03.016

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    sciencedirect.com/science/article/pii/S1097276522002544
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    Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
    1
    1. scibot 07 Apr 2022
      Plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124722003722
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
    1
    1. scibot 01 Apr 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  7. Mar 2022
  8. elifesciences.org elifesciences.org
    Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking
    1
    1. scibot 31 Mar 2022
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      DOI: 10.7554/eLife.69229

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    elifesciences.org/articles/69229
  9. academic.oup.com academic.oup.com
    Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
    1
    1. scibot 31 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1093/nar/gkac178

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac178/6553119
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    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
    1
    1. scibot 30 Mar 2022
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2211124722003035
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    Pathogen hijacks programmed cell death signaling by arginine ADPR-deacylization of caspases
    1
    1. scibot 27 Mar 2022
      AddgeneCat# 12259

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    sciencedirect.com/science/article/pii/S1097276522002192
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    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
    1
    1. scibot 27 Mar 2022
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    sciencedirect.com/science/article/pii/S1074761322001248
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    A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screens
    1
    1. scibot 26 Mar 2022
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    sciencedirect.com/science/article/pii/S2405471222000849
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
    1
    1. scibot 26 Mar 2022
      RRID:Addgene_12259

      DOI: 10.3390/cancers14061375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8945883/
  15. 52.53.155.43 52.53.155.43
    Optochemical Control of mTOR Signaling and mTOR-Dependent Autophagy
    1
    1. scibot 24 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1021/acsptsci.1c00230

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    52.53.155.43/5f0a00228a932c0536b21b4ce3c5456b55ea2744/acsptsci.1c00230-html.html
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    The mTOR chromatin-bound interactome in prostate cancer
    1
    1. scibot 23 Mar 2022
      addgeneCat# 12259

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    sciencedirect.com/science/article/pii/S2211124722002753
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    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
    1
    1. scibot 18 Mar 2022
      AddgeneCat#12259

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    sciencedirect.com/science/article/pii/S1550413122000535
  18. www.sciencedirect.com www.sciencedirect.com
    CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome
    1
    1. scibot 18 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002741
  19. www.nature.com www.nature.com
    Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples
    1
    1. scibot 18 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1038/s41551-022-00850-0

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    nature.com/articles/s41551-022-00850-0
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer
    1
    1. scibot 18 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1158/0008-5472.CAN-20-2811

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    ncbi.nlm.nih.gov/pmc/articles/PMC8448980/
  21. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
    1
    1. scibot 16 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002583
  22. www.sciencedirect.com www.sciencedirect.com
    Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
    1
    1. scibot 16 Mar 2022
      plasmid_12259

      DOI: 10.1016/j.neuron.2022.02.017

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    sciencedirect.com/science/article/pii/S0896627322001842
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations
    1
    1. scibot 15 Mar 2022
      plasmid_12259

      DOI: 10.3390/cells11050854

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    ncbi.nlm.nih.gov/pmc/articles/PMC8909053/
  24. www.sciencedirect.com www.sciencedirect.com
    Generation of highly pure motor neurons from human induced pluripotent stem cells
    1
    1. scibot 11 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.xpro.2022.101223

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    sciencedirect.com/science/article/pii/S2666166722001034
  25. www.sciencedirect.com www.sciencedirect.com
    Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors
    1
    1. scibot 09 Mar 2022
      Addgene12259

      DOI: 10.1016/j.cell.2022.02.002

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    sciencedirect.com/science/article/pii/S0092867422001428
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses
    1
    1. scibot 09 Mar 2022
      RRID:Addgene_12259

      DOI: 10.3389/fphys.2022.769325

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    ncbi.nlm.nih.gov/pmc/articles/PMC8895044/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells
    1
    1. scibot 09 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1093/narcan/zcac007

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    ncbi.nlm.nih.gov/pmc/articles/PMC8892060/
  28. www.sciencedirect.com www.sciencedirect.com
    Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms
    1
    1. scibot 09 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110476

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    sciencedirect.com/science/article/pii/S2211124722002091
  29. www.sciencedirect.com www.sciencedirect.com
    Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication
    1
    1. scibot 09 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2022.110469

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    sciencedirect.com/science/article/pii/S2211124722002029
  30. www.sciencedirect.com www.sciencedirect.com
    Local hyperthermia therapy induces browning of white fat and treats obesity
    1
    1. scibot 06 Mar 2022
      AddgeneCat# 12259

      DOI: 10.1016/j.cell.2022.02.004

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    sciencedirect.com/science/article/pii/S0092867422001441
  31. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
    1
    1. scibot 05 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1158/2767-9764.CRC-21-0103

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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  32. www.nature.com www.nature.com
    Genetically encoded BRET-activated photodynamic therapy for the treatment of deep-seated tumors
    1
    1. scibot 05 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1038/s41377-022-00729-4

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    nature.com/articles/s41377-022-00729-4
  33. www.nature.com www.nature.com
    Generation of CRISPR–Cas9-mediated genetic knockout human intestinal tissue–derived enteroid lines by lentivirus transduction and single-cell cloning
    1
    1. scibot 05 Mar 2022
      RRID:Addgene_12259

      DOI: 10.1038/s41596-021-00669-0

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    nature.com/articles/s41596-021-00669-0
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
    1
    1. scibot 04 Mar 2022
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      DOI: 10.7554/eLife.65421

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    ncbi.nlm.nih.gov/pmc/articles/PMC8865852/
  35. elifesciences.org elifesciences.org
    Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity
    1
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      DOI: 10.7554/eLife.66869

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    elifesciences.org/articles/66869
  36. www.sciencedirect.com www.sciencedirect.com
    Full-length and split-NanoLuc reporters identify pathogenic COL4A5 nonsense mutations susceptible to premature termination codon readthrough
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    sciencedirect.com/science/article/pii/S2589004222001614
  37. www.sciencedirect.com www.sciencedirect.com
    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
    1
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    sciencedirect.com/science/article/pii/S2211124722001498
  38. www.sciencedirect.com www.sciencedirect.com
    Recruitment of DNA to tumor-derived microvesicles
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      DOI: 10.1016/j.celrep.2022.110443

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    sciencedirect.com/science/article/pii/S221112472200170X
  39. Feb 2022
  40. www.sciencedirect.com www.sciencedirect.com
    High-throughput identification of autoantibodies that target the human exoproteome
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      DOI: 10.1016/j.crmeth.2022.100172

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    sciencedirect.com/science/article/pii/S2667237522000248
  41. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
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      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  42. www.sciencedirect.com www.sciencedirect.com
    Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing
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    sciencedirect.com/science/article/pii/S2211124722000766
  43. www.sciencedirect.com www.sciencedirect.com
    Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination
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      DOI: 10.1016/j.celrep.2022.110388

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    sciencedirect.com/science/article/pii/S2211124722001097
  44. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
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    pubmed.ncbi.nlm.nih.gov/35172133/
  45. www.sciencedirect.com www.sciencedirect.com
    Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
    2
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      DOI: 10.1016/j.isci.2022.103842

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
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    Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
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    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
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    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
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    Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
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    Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts
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    Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
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  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
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    Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death
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    Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death
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  58. journals.biologists.com journals.biologists.com
    Contribution of protein-protein interactions to the endothelial barrier-stabilizing function of KRIT1
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  59. Jan 2022
  60. www.sciencedirect.com www.sciencedirect.com
    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II
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    The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression
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  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Selective Small-Molecule c-Myc Degrader Potently Regresses Lethal c-Myc Overexpressing Tumors
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
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    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans
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    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation
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    p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function
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    Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice
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  73. Dec 2021
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    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
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    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
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  76. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
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    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
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    Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TIFAB Accelerates MLL-AF9−Induced Acute Myeloid Leukemia Through Upregulation of HOXA9
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
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  82. www.sciencedirect.com www.sciencedirect.com
    Structure, mechanism, and inhibition of Hedgehog acyltransferase
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    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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    A mechanistic basis for the malignant progression of salivary gland tumors
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    NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8610276/
  88. Nov 2021
  89. www.sciencedirect.com www.sciencedirect.com
    Deciphering cell signaling networks with massively multiplexed biosensor barcoding
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    1. scibot 30 Nov 2021
      plasmid_12259

      DOI: 10.1016/j.cell.2021.11.005

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    sciencedirect.com/science/article/pii/S0092867421013209
  90. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    1. scibot 24 Nov 2021
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    sciencedirect.com/science/article/pii/S2211124721015424
  91. www.sciencedirect.com www.sciencedirect.com
    PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
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    1. scibot 23 Nov 2021
      Addgene, Cat# 12259

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    sciencedirect.com/science/article/pii/S2451945621004785
  92. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    1
    1. scibot 19 Nov 2021
      Addgene_12259

      DOI: 10.1016/j.neuron.2021.10.036

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    sciencedirect.com/science/article/pii/S0896627321008667
  93. www.sciencedirect.com www.sciencedirect.com
    Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro
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      Addgene #12259

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    sciencedirect.com/science/article/pii/S2666166721006626
  94. www.sciencedirect.com www.sciencedirect.com
    Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2
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    1. scibot 18 Nov 2021
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    sciencedirect.com/science/article/pii/S2589004221012645
  95. www.nature.com www.nature.com
    Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
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    nature.com/articles/s41467-021-26530-2
  96. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    1. scibot 10 Nov 2021
      plasmid_12259

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    sciencedirect.com/science/article/pii/S2211124721014583
  97. www.sciencedirect.com www.sciencedirect.com
    Modulating mesendoderm competence during human germ layer differentiation
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    1. scibot 10 Nov 2021
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    sciencedirect.com/science/article/pii/S2211124721014698
  98. www.nature.com www.nature.com
    RNA-responsive elements for eukaryotic translational control
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      RRID:Addgene_12259

      DOI: 10.1038/s41587-021-01068-2

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    nature.com/articles/s41587-021-01068-2
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.71966

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553338/
  100. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
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    1. scibot 05 Nov 2021
      plasmid_12259

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    elifesciences.org/articles/67886
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKAP79 enables calcineurin to directly suppress protein kinase A activity
    1
    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.68164

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    ncbi.nlm.nih.gov/pmc/articles/PMC8560092/
  102. www.sciencedirect.com www.sciencedirect.com
    A multi-omic single-cell landscape of human gynecologic malignancies
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    1. scibot 05 Nov 2021
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    sciencedirect.com/science/article/pii/S109727652100842X
  103. www.sciencedirect.com www.sciencedirect.com
    A synthetic gene circuit for imaging-free detection of signaling pulses
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    sciencedirect.com/science/article/pii/S2405471221004130
  104. Oct 2021
  105. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
    1
    1. scibot 29 Oct 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2589004221011925
  106. www.jneurosci.org www.jneurosci.org
    Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells
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      Addgene #12259

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    jneurosci.org/content/41/42/8710
  107. www.sciencedirect.com www.sciencedirect.com
    GCN2 adapts protein synthesis to scavenging-dependent growth
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      Addgene_12259

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    sciencedirect.com/science/article/pii/S2405471221003823
  108. www.sciencedirect.com www.sciencedirect.com
    Direct conversion of adult fibroblasts into motor neurons
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    1. scibot 26 Oct 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2666166721006237
  109. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    1. scibot 23 Oct 2021
      12259

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    sciencedirect.com/science/article/pii/S1097276521008340
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
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    1. scibot 23 Oct 2021
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      DOI: 10.7554/eLife.65672

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    ncbi.nlm.nih.gov/pmc/articles/PMC8523159/
  111. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
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      RRID:Addgene 12259

      DOI: 10.1016/j.cub.2021.09.067

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    sciencedirect.com/science/article/pii/S0960982221013233
  112. www.sciencedirect.com www.sciencedirect.com
    Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications
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    1. scibot 22 Oct 2021
      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S2666166721005803
  113. www.sciencedirect.com www.sciencedirect.com
    A synaptic temperature sensor for body cooling
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      12259

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    sciencedirect.com/science/article/pii/S0896627321007698
  114. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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      12259

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    sciencedirect.com/science/article/pii/S109727652100798X
  115. www.sciencedirect.com www.sciencedirect.com
    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
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    1. scibot 21 Oct 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15631

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15631
  117. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Andrographolide prevents bone loss via targeting ERRalpha-regulated metabolic adaption of osteoclastogenesis
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      DOI: 10.1111/bph.15614

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15614
  118. www.sciencedirect.com www.sciencedirect.com
    Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
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    sciencedirect.com/science/article/pii/S2589004221011366
  119. www.sciencedirect.com www.sciencedirect.com
    Tyrosine Phosphorylation of DEPTOR Functions as a Molecular Switch to Activate mTOR Signaling
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      RRID:Addgene_12259

      DOI: 10.1016/j.jbc.2021.101291

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    sciencedirect.com/science/article/pii/S0021925821010966
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A highly potent antibody effective against SARS-CoV-2 variants of concern
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      RRID:Addgene_12259

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    ncbi.nlm.nih.gov/pmc/articles/PMC8452523/
  121. www.sciencedirect.com www.sciencedirect.com
    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
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      RRID:Addgene_12259

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    sciencedirect.com/science/article/pii/S1534580721007334
  122. www.science.org www.science.org
    Interpretation of cancer mutations using a multiscale map of protein systems
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      DOI: 10.1126/science.abf3067

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    science.org/doi/abs/10.1126/science.abf3067
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis
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      DOI: 10.1165/rcmb.2020-0544OC

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    ncbi.nlm.nih.gov/pmc/articles/PMC8485999/
  124. www.sciencedirect.com www.sciencedirect.com
    Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
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    sciencedirect.com/science/article/pii/S2589004221011172
  125. www.sciencedirect.com www.sciencedirect.com
    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
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    sciencedirect.com/science/article/pii/S2666166721005761
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Initial Characterization of Cellular Models for COG Complex-Related CDG-II Diseases
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      DOI: 10.3389/fgene.2021.733048

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    ncbi.nlm.nih.gov/pmc/articles/PMC8484713/
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system
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  128. Sep 2021
  129. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
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    sciencedirect.com/science/article/pii/S0092867421010539
  130. www.sciencedirect.com www.sciencedirect.com
    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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    sciencedirect.com/science/article/pii/S0092867421010527
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ observation of mitochondrial biogenesis as the early event of apoptosis
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  132. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
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      12259

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    sciencedirect.com/science/article/pii/S1097276521007292
  133. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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  134. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
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    Assessing the Wnt-reactivity of cytonemes of mouse embryonic stem cells using a bioengineering approach
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  136. www.sciencedirect.com www.sciencedirect.com
    Pro-inflammatory and proliferative microglia drive progression of glioblastoma
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFP36L2 Role in Thyroid Functionality
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  138. www.sciencedirect.com www.sciencedirect.com
    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2
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    Cilium induction triggers differentiation of glioma stem cells
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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  144. Aug 2021
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
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  146. www.sciencedirect.com www.sciencedirect.com
    Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
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    Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy
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    A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR)
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  151. www.sciencedirect.com www.sciencedirect.com
    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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  152. www.embopress.org www.embopress.org
    The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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  155. www.sciencedirect.com www.sciencedirect.com
    Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro
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  156. www.mdpi.com www.mdpi.com
    Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide
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  157. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
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  159. www.biorxiv.org www.biorxiv.org
    Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma
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    Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases
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    A flow cytometry-based assay for serological detection of anti-spike antibodies in COVID-19 patients
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  163. www.sciencedirect.com www.sciencedirect.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
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    Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable Gag anchoring
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    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer
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  172. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects
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      Addgene catalog no. 12259

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  174. www.sciencedirect.com www.sciencedirect.com
    ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
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  176. elifesciences.org elifesciences.org
    Subcellular drug targeting illuminates local kinase action
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    Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats
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  178. www.sciencedirect.com www.sciencedirect.com
    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610821003846
  179. www.sciencedirect.com www.sciencedirect.com
    Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells
    1
    1. scibot 06 Aug 2021
      Plasmid_12259

      DOI: 10.1016/j.cmet.2021.07.015

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    sciencedirect.com/science/article/pii/S1550413121003314
  180. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
    1
    1. scibot 05 Aug 2021
      addgene_12259

      DOI: 10.1016/j.chom.2018.11.001

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    sciencedirect.com/science/article/pii/S1931312818305584
  181. www.sciencedirect.com www.sciencedirect.com
    The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation
    1
    1. scibot 04 Aug 2021
      Addgene_12259

      DOI: 10.1016/j.celrep.2021.109468

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    sciencedirect.com/science/article/pii/S2211124721008913
  182. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 04 Aug 2021
      Addgene_12259

      DOI: 10.1016/j.cell.2018.11.038

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    sciencedirect.com/science/article/pii/S0092867418315630
  183. www.mdpi.com www.mdpi.com
    Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation
    1
    1. scibot 04 Aug 2021
      Addgene_12259

      DOI: 10.3390/ijms22147753

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    mdpi.com/1422-0067/22/14/7753
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 04 Aug 2021
      Addgene_12259

      DOI: 10.7554/eLife.25287

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    ncbi.nlm.nih.gov/pmc/articles/PMC5495570/
  185. www.sciencedirect.com www.sciencedirect.com
    Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells
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    1. scibot 03 Aug 2021
      Addgene 12259

      DOI: 10.1016/j.chembiol.2021.07.011

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    sciencedirect.com/science/article/pii/S2451945621003512
  186. jitc.biomedcentral.com jitc.biomedcentral.com
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    1. scibot 02 Aug 2021
      plasmid_12259

      DOI: 10.1186/s40425-019-0575-3

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    jitc.biomedcentral.com/articles/10.1186/s40425-019-0575-3
  187. www.sciencedirect.com www.sciencedirect.com
    Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
    1
    1. scibot 01 Aug 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.celrep.2021.109460

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    sciencedirect.com/science/article/pii/S2211124721008834
  188. www.sciencedirect.com www.sciencedirect.com
    DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression
    1
    1. scibot 01 Aug 2021
      Addgene_12259

      DOI: 10.1016/j.celrep.2019.10.025

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    sciencedirect.com/science/article/pii/S2211124719313257
  189. Jul 2021
  190. www.sciencedirect.com www.sciencedirect.com
    Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia
    1
    1. scibot 31 Jul 2021
      Addgene_12259

      DOI: 10.1016/j.ccell.2018.11.001

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    sciencedirect.com/science/article/pii/S1535610818304835
  191. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 31 Jul 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.stem.2019.02.006

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    sciencedirect.com/science/article/pii/S1934590919300487
  192. www.sciencedirect.com www.sciencedirect.com
    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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    1. scibot 31 Jul 2021
      RRID:Addgene_12259

      DOI: 10.1016/j.cell.2019.01.025

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    sciencedirect.com/science/article/pii/S0092867419300583
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 31 Jul 2021
      RRID:Addgene_12259

      DOI: 10.7554/eLife.43511

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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  194. www.sciencedirect.com www.sciencedirect.com
    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
    1
    1. scibot 30 Jul 2021
      RRID: Addgene_12259

      DOI: 10.1016/j.celrep.2019.12.017

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    sciencedirect.com/science/article/pii/S2211124719316675
  195. www.sciencedirect.com www.sciencedirect.com
    Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype
    1
    1. scibot 30 Jul 2021
      Addgene 12259

      DOI: 10.1016/j.celrep.2019.12.002

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    sciencedirect.com/science/article/pii/S2211124719316419
  196. www.sciencedirect.com www.sciencedirect.com
    Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A
    1
    1. scibot 30 Jul 2021
      AddgeneCat# 12259

      DOI: 10.1016/j.celrep.2019.11.066

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    sciencedirect.com/science/article/pii/S2211124719315578
  197. www.sciencedirect.com www.sciencedirect.com
    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
    1
    1. scibot 30 Jul 2021
      RRID: Addgene_12259

      DOI: 10.1016/j.devcel.2019.11.012

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    sciencedirect.com/science/article/pii/S1534580719309438
  198. www.sciencedirect.com www.sciencedirect.com
    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
    1
    1. scibot 30 Jul 2021
      vsv-g expression vector (pMD2.G) (lentiviral helper plasmid)

      DOI: 10.1016/j.cell.2019.09.011

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    sciencedirect.com/science/article/pii/S0092867419310177
  199. www.nature.com www.nature.com
    High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
    1
    1. scibot 30 Jul 2021
      pMDG.2

      DOI: 10.1038/s41551-019-0454-8

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    nature.com/articles/s41551-019-0454-8
  200. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
    1
    1. scibot 30 Jul 2021
      pMD2.G

      DOI: 10.1016/j.molcel.2019.07.021

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    sciencedirect.com/science/article/pii/S1097276519305519
  201. link.springer.com link.springer.com
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    1. scibot 30 Jul 2021
      plasmid_12259

      DOI: 10.1186/s40425-019-0575-3

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    link.springer.com/article/10.1186/s40425-019-0575-3
  202. www.sciencedirect.com www.sciencedirect.com
    The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression
    1
    1. scibot 30 Jul 2021
      Addgene_12259

      DOI: 10.1016/j.molcel.2018.01.011

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    sciencedirect.com/science/article/pii/S1097276518300406
  203. www.sciencedirect.com www.sciencedirect.com
    Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection
    1
    1. scibot 29 Jul 2021
      Plasmid #12259

      DOI: 10.1016/j.celrep.2019.10.129

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    sciencedirect.com/science/article/pii/S2211124719314627
  204. www.sciencedirect.com www.sciencedirect.com
    Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits
    1
    1. scibot 29 Jul 2021
      Addgene:12259

      DOI: 10.1016/j.neuron.2019.10.002

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      RRID:Addgene_12259 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S0896627319308505