1,652 Matching Annotations
  1. Feb 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Monitoring cell fate in 3D organotypic human squamous epithelial cultures
    1
    1. scibot 09 Feb 2023
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    sciencedirect.com/science/article/pii/S266616672300059X
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression
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    1. scibot 09 Feb 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357060/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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    1. scibot 09 Feb 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
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    1. scibot 08 Feb 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9884621/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357105/
  7. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
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    nature.com/articles/s41467-023-36058-2
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    Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6
    1
    1. scibot 02 Feb 2023
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    link.springer.com/article/10.1007/s12035-023-03232-y
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The endothelial-enriched lncRNA LINC00607 mediates angiogenic function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9879848/
  11. Jan 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation
    1
    1. scibot 28 Jan 2023
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    sciencedirect.com/science/article/pii/S221112472201796X
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies
    1
    1. scibot 28 Jan 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9876383/
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
    1
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    sciencedirect.com/science/article/pii/S1934590922004945
  15. www.science.org www.science.org
    Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases
    1
    1. scibot 27 Jan 2023
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      DOI: 10.1126/sciimmunol.abp9765

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    science.org/doi/10.1126/sciimmunol.abp9765
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
    1
    1. scibot 27 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124723000487
  17. www.mdpi.com www.mdpi.com
    Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins
    1
    1. scibot 26 Jan 2023
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    mdpi.com/1999-4915/15/2/262
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    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
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    1. scibot 26 Jan 2023
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    sciencedirect.com/science/article/pii/S1097276522012175
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CoQ Regulates Brown Adipose Tissue Respiration and Uncoupling Protein 1 Expression
    1
    1. scibot 25 Jan 2023
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      DOI: 10.3390/antiox12010014

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Attenuating iPSC reprogramming stress with dominant-negative BET peptides
    1
    1. scibot 25 Jan 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9860338/
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    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
    1
    1. scibot 24 Jan 2023
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    sciencedirect.com/science/article/pii/S2211124723000426
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects
    1
    1. scibot 22 Jan 2023
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      DOI: 10.1158/1078-0432.CCR-22-1703

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    ncbi.nlm.nih.gov/pmc/articles/PMC9843434/
  23. www.sciencedirect.com www.sciencedirect.com
    TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis
    1
    1. scibot 21 Jan 2023
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S2211124723000232
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    Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.xpro.2023.102055

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    sciencedirect.com/science/article/pii/S2666166723000138
  25. www.biorxiv.org www.biorxiv.org
    Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia
    1
    1. scibot 20 Jan 2023
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      DOI: 10.1101/2023.01.12.523716

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    biorxiv.org/content/10.1101/2023.01.12.523716v2
  26. www.biorxiv.org www.biorxiv.org
    Actin nucleators safeguard replication forks by limiting nascent strand degradation
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    1. scibot 20 Jan 2023
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      DOI: 10.1101/2023.01.12.523639

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    biorxiv.org/content/10.1101/2023.01.12.523639v1
  27. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
    1
    1. scibot 19 Jan 2023
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    sciencedirect.com/science/article/pii/S1535610822005943
  28. www.sciencedirect.com www.sciencedirect.com
    Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.cell.2022.12.043

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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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    1. scibot 18 Jan 2023
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      DOI: 10.1038/s41467-022-35757-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC9839780/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  31. journals.lww.com journals.lww.com
    Oncogenic BRAFV600E induces microglial proliferation... : Neural Regeneration Research
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      DOI: 10.4103/1673-5374.361516

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    journals.lww.com/nrronline/Fulltext/2023/07000/Oncogenic_BRAFV600E_induces_microglial.38.aspx
  32. 52.53.155.43 52.53.155.43
    SSRN-id4267401-html.html
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  33. rupress.org rupress.org
    Fibroblasts secrete fibronectin under lamellipodia in a microtubule- and myosin II–dependent fashion
    1
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      DOI: 10.1083/jcb.202204100

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    rupress.org/jcb/article/222/2/e202204100/213712/Fibroblasts-secrete-fibronectin-under-lamellipodia
  34. www.pnas.org www.pnas.org
    Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs
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      DOI: 10.1073/pnas.2215071120

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    pnas.org/doi/abs/10.1073/pnas.2215071120
  35. www.sciencedirect.com www.sciencedirect.com
    DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
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    sciencedirect.com/science/article/pii/S2211124722018903
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens
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      DOI: 10.1371/journal.ppat.1010800

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    ncbi.nlm.nih.gov/pmc/articles/PMC9829182/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses
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    ncbi.nlm.nih.gov/pmc/articles/PMC9794394/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9826815/
  39. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
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    sciencedirect.com/science/article/pii/S009286742201529X
  40. www.sciencedirect.com www.sciencedirect.com
    PTBP1-activated co-transcriptional splicing controls epigenetic status of pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1097276522011716
  41. www.sciencedirect.com www.sciencedirect.com
    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1074761322006045
  42. www.sciencedirect.com www.sciencedirect.com
    Resurrection of endogenous retroviruses during aging reinforces senescence
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    sciencedirect.com/science/article/pii/S0092867422015306
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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      DOI: 10.1158/2159-8290.CD-21-1671

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    ncbi.nlm.nih.gov/pmc/articles/PMC9437570/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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    Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells
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  48. www.cell.com www.cell.com
    Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
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  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
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    Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Virus-like particle – mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection
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  53. aacrjournals.org aacrjournals.org
    Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing
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    aacrjournals.org/cancerres/article/82/17/3002/708290/Efficient-Correction-of-Oncogenic-KRAS-and-TP53
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    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
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    Engineered cell entry links receptor biology with single-cell genomics
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bulk IgG Glycosylation Predicts COVID-19 Severity and Vaccine Antibody Response
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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    Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium
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  62. aacrjournals.org aacrjournals.org
    Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
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  63. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation
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  65. www.sciencedirect.com www.sciencedirect.com
    BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
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    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
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  67. Nov 2022
  68. www.nature.com www.nature.com
    Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    Autophagy promotes cell survival by maintaining NAD levels
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  71. 52.53.155.43 52.53.155.43
    Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
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  76. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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  78. www.pnas.org www.pnas.org
    Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
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    Genome-scale CRISPR screening in a single mouse liver
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    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
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    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
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    Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
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    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
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  86. rupress.org rupress.org
    Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis
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  87. www.sciencedirect.com www.sciencedirect.com
    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron
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    1. scibot 04 Nov 2022
      Addgene #12260

      DOI: 10.1016/j.isci.2022.105316

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    2. scibot 04 Nov 2022
      Addgene_12260

      DOI: 10.1016/j.isci.2022.105316

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    ncbi.nlm.nih.gov/pmc/articles/PMC9549715/
  89. www.sciencedirect.com www.sciencedirect.com
    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
    1
    1. scibot 04 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.10.002

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    sciencedirect.com/science/article/pii/S1535610822004937
  90. www.sciencedirect.com www.sciencedirect.com
    Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis
    1
    1. scibot 04 Nov 2022
      plasmid_12

      DOI: 10.1016/j.stem.2022.10.005

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    sciencedirect.com/science/article/pii/S1934590922004234
  91. www.sciencedirect.com www.sciencedirect.com
    Multiphase coalescence mediates Hippo pathway activation
    1
    1. scibot 03 Nov 2022
      12260

      DOI: 10.1016/j.cell.2022.09.036

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    sciencedirect.com/science/article/pii/S0092867422012557
  92. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.str.2022.10.003

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    sciencedirect.com/science/article/pii/S0969212622003926
  93. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
    1
    1. scibot 03 Nov 2022
      plasmid_12260

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    sciencedirect.com/science/article/pii/S1097276522009625
  94. www.nature.com www.nature.com
    HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41467-022-34252-2

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    nature.com/articles/s41467-022-34252-2
  95. www.nature.com www.nature.com
    HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
    1
    1. scibot 02 Nov 2022
      plasmid_12260

      DOI: 10.1038/s41598-022-21714-2

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    nature.com/articles/s41598-022-21714-2
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS
    1
    1. scibot 02 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1083/jcb.202201024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9617480/
  97. Oct 2022
  98. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
    1
    1. scibot 27 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1158/1078-0432.CCR-22-0991

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    aacrjournals.org/clincancerres/article/28/20/4521/709577/CircIPO7-Promotes-Nasopharyngeal-Carcinoma
  99. www.sciencedirect.com www.sciencedirect.com
    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
    1
    1. scibot 26 Oct 2022
      12260

      DOI: 10.1016/j.celrep.2022.111546

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    sciencedirect.com/science/article/pii/S2211124722014024
  100. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
    1
    1. scibot 26 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111561

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    sciencedirect.com/science/article/pii/S221112472201422X
  101. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
    1
    1. scibot 20 Oct 2022
      plasmid_12260

      DOI: 10.1016/j.celrep.2022.111514

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    sciencedirect.com/science/article/pii/S221112472201364X
  102. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    1. scibot 15 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1007/s00018-022-04586-7

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    link.springer.com/article/10.1007/s00018-022-04586-7
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
    1
    1. scibot 12 Oct 2022
      Addgene_12260

      DOI: 10.1158/2643-3230.BCD-21-0115

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414116/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
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    1. scibot 12 Oct 2022
      Addgene_12260

      DOI: 10.1016/j.isci.2022.105172

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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
    1
    1. scibot 12 Oct 2022
      plasmid_12260

      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  106. www.nature.com www.nature.com
    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
    1
    1. scibot 11 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41587-022-01494-w

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    nature.com/articles/s41587-022-01494-w
  107. www.sciencedirect.com www.sciencedirect.com
    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
    1
    1. scibot 09 Oct 2022
      RRID:Addgene_1226

      DOI: 10.1016/j.cell.2022.09.020

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    sciencedirect.com/science/article/pii/S0092867422011928
  108. www.nature.com www.nature.com
    Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression
    1
    1. scibot 08 Oct 2022
      Plasmid_12260

      DOI: 10.1038/s41596-022-00741-3

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    nature.com/articles/s41596-022-00741-3
  109. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    1. scibot 07 Oct 2022
      Cat#12260

      DOI: 10.1016/j.molcel.2022.09.007

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    sciencedirect.com/science/article/pii/S1097276522008966
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells
    1
    1. scibot 07 Oct 2022
      RRID:Addgene_12260

      DOI: 10.3389/fcell.2022.929495

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    ncbi.nlm.nih.gov/pmc/articles/PMC9527304/
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
    1
    1. scibot 02 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2022.105050

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
  112. Sep 2022
  113. www.sciencedirect.com www.sciencedirect.com
    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
    1
    1. scibot 30 Sep 2022
      AddGene#12260

      DOI: 10.1016/j.immuni.2022.09.001

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    sciencedirect.com/science/article/pii/S1074761322004149
  114. www.sciencedirect.com www.sciencedirect.com
    Opto-katanin, an optogenetic tool for localized, microtubule disassembly
    1
    1. scibot 29 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.cub.2022.09.010

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    sciencedirect.com/science/article/pii/S0960982222014543
  115. www.sciencedirect.com www.sciencedirect.com
    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
    1
    1. scibot 29 Sep 2022
      plasmid_12260

      DOI: 10.1016/j.devcel.2022.09.003

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    sciencedirect.com/science/article/pii/S1534580722006335
  116. www.sciencedirect.com www.sciencedirect.com
    The lncRNA ALPHA specifically targets chikungunya virus to control infection
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    1. scibot 27 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2022.08.030

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    sciencedirect.com/science/article/pii/S1097276522008504
  117. www.sciencedirect.com www.sciencedirect.com
    A screening-compatible live cell fluorescence resonance energy transfer-based assay for modulation of Rho GTPase activity
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    1. scibot 24 Sep 2022
      Addgene_12260

      DOI: 10.1016/j.xpro.2022.101705

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    sciencedirect.com/science/article/pii/S2666166722005858
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study
    1
    1. scibot 22 Sep 2022
      Addgene_12260

      DOI: 10.4274/jtgga.galenos.2022.2022-1-14

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    ncbi.nlm.nih.gov/pmc/articles/PMC9450920/
  119. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
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    1. scibot 22 Sep 2022
      Addgene_12260

      DOI: 10.1242/jcs.258396

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    journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
  120. www.sciencedirect.com www.sciencedirect.com
    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
    2
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111344

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      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111344

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    sciencedirect.com/science/article/pii/S221112472201172X
  121. www.sciencedirect.com www.sciencedirect.com
    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111361

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    sciencedirect.com/science/article/pii/S2211124722011937
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
    1
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.1136/gutjnl-2021-324994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9271144/
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation
    1
    1. scibot 22 Sep 2022
      RRID:Addgene_12260

      DOI: 10.3389/fendo.2022.932286

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    ncbi.nlm.nih.gov/pmc/articles/PMC9483015/
  124. www.sciencedirect.com www.sciencedirect.com
    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
    1
    1. scibot 21 Sep 2022
      Plasmid - psPAX2

      DOI: 10.1016/j.celrep.2022.111390

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    sciencedirect.com/science/article/pii/S221112472201227X
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
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    1. scibot 21 Sep 2022
      plasmid_12260

      DOI: 10.1371/journal.pbio.3001754

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    ncbi.nlm.nih.gov/pmc/articles/PMC9469972/
  126. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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    1. scibot 20 Sep 2022
      Addgene plasmid #12260

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    sciencedirect.com/science/article/pii/S2666166722005627
  127. www.sciencedirect.com www.sciencedirect.com
    Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells
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      RRID:Addgene_12260

      DOI: 10.1016/j.xpro.2022.101675

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  128. www.sciencedirect.com www.sciencedirect.com
    SerpinB3 drives cancer stem cell survival in glioblastoma
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      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111348

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  129. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
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    1. scibot 15 Sep 2022
      RRID:Addgene_12

      DOI: 10.1111/cas.15558

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    onlinelibrary.wiley.com/doi/10.1111/cas.15558
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer
    1
    1. scibot 14 Sep 2022
      RRID:Addgene_12260

      DOI: 10.3390/cancers14174219

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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
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    Human coronaviruses disassemble processing bodies
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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    TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
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    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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    Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites
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  146. 52.53.155.43 52.53.155.43
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  147. 52.53.155.43 52.53.155.43
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions
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    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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    RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
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    Comprehensive analysis of mycobacterium tuberculosis antigen-specific CD4+ T cell responses restricted by single HLA class II allotype in an individual
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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  159. journals.plos.org journals.plos.org
    Genome-wide screening identified SEC61A1 as an essential factor for mycolactone-dependent apoptosis in human premonocytic THP-1 cells
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    Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine
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    Protein Scaffold‐Based Multimerization of Soluble ACE2 Efficiently Blocks SARS‐CoV‐2 Infection In Vitro and In Vivo
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  165. rupress.org rupress.org
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    METTL14-dependent m6A modification controls iNKT cell development and function
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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  169. Jul 2022
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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  172. 52.53.155.43 52.53.155.43
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  174. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  175. 52.53.155.43 52.53.155.43
    can-21-3713-html.html
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    1. scibot 29 Jul 2022
      RRID:Addgene_122

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  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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  177. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15896
  178. www.sciencedirect.com www.sciencedirect.com
    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    1. scibot 27 Jul 2022
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    sciencedirect.com/science/article/pii/S2666379122002221
  179. www.sciencedirect.com www.sciencedirect.com
    Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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    sciencedirect.com/science/article/pii/S2666379122002336
  180. www.sciencedirect.com www.sciencedirect.com
    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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    sciencedirect.com/science/article/pii/S2211124722008713
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the transcriptional activity of STAT3 by a novel fusion protein
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      plasmid_12260

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    ncbi.nlm.nih.gov/pmc/articles/PMC9271252/
  182. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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    sciencedirect.com/science/article/pii/S2211124722008257
  183. Jun 2022
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/0008-5472.CAN-21-1256

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  185. 52.53.155.43 52.53.155.43
    cd-21-0680-html.html
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  186. 52.53.155.43 52.53.155.43
    mcr-22-0111-html.html
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  187. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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    embopress.org/doi/10.15252/embr.202154133
  188. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
  189. link.springer.com link.springer.com
    Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
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  190. www.sciencedirect.com www.sciencedirect.com
    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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    1. scibot 22 Jun 2022
      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S2451945622002045
  191. www.sciencedirect.com www.sciencedirect.com
    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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      AddgeneCat# 12260

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  192. www.sciencedirect.com www.sciencedirect.com
    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    sciencedirect.com/science/article/pii/S2667237522001084
  193. www.sciencedirect.com www.sciencedirect.com
    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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      plasmid_12260

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  194. www.sciencedirect.com www.sciencedirect.com
    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
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    1. scibot 15 Jun 2022
      AddgeneCat. No.: 12260

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  195. www.sciencedirect.com www.sciencedirect.com
    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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    1. scibot 15 Jun 2022
      Plasmid_12260

      DOI: 10.7554/eLife.68598

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    ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
  197. www.nature.com www.nature.com
    RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
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      DOI: 10.1038/s41467-022-30794-7

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    nature.com/articles/s41467-022-30794-7
  198. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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    1. scibot 10 Jun 2022
      RRID:Addgene_12260

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    sciencedirect.com/science/article/pii/S2666379122001872
  199. www.sciencedirect.com www.sciencedirect.com
    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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    1. scibot 09 Jun 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.cels.2022.05.003

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    sciencedirect.com/science/article/pii/S2405471222002241
  200. www.sciencedirect.com www.sciencedirect.com
    Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD
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      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.110913

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    sciencedirect.com/science/article/pii/S2211124722006908
  201. www.sciencedirect.com www.sciencedirect.com
    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
    2
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      AddgeneCat# 12260

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    sciencedirect.com/science/article/pii/S1097276522004439
  202. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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      RRID:Addgene_12260

      DOI: 10.1007/s10120-022-01307-8

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    link.springer.com/article/10.1007/s10120-022-01307-8
  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
    1
    1. scibot 07 Jun 2022
      Addgene_12260

      DOI: 10.7150/jca.54402

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