79 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 24 May 2024
      plasmid_12371

      DOI: 10.1038/s41467-024-48508-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11109152/
  3. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
    1
    1. scibot 23 May 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  4. www.sciencedirect.com www.sciencedirect.com
    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
    1
    1. scibot 23 May 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.114261

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    sciencedirect.com/science/article/pii/S2211124724005898
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell help shapes B cell tolerance
    1
    1. scibot 19 May 2024
      12371

      DOI: 10.1126/sciimmunol.adj7029

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095409/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
    1
    1. scibot 19 May 2024
      12371

      DOI: 10.1126/sciadv.adk9076

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095456/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting senescent cells with NKG2D-CAR T cells
    1
    1. scibot 12 May 2024
      12371

      DOI: 10.1038/s41420-024-01976-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11069534/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
    1
    1. scibot 12 May 2024
      12371

      DOI: 10.1126/sciadv.adh0798

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    ncbi.nlm.nih.gov/pmc/articles/PMC11078192/
  9. Apr 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer
    1
    1. scibot 14 Apr 2024
      12371

      DOI: 10.1126/sciadv.adk1031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10990278/
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL
    1
    1. scibot 27 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1084/jem.20230941

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959178/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for self-discrimination by neoantigen-specific TCRs
    1
    1. scibot 17 Mar 2024
      Addgene_12371

      DOI: 10.1038/s41467-024-46367-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924104/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression
    1
    1. scibot 16 Mar 2024
      12371

      DOI: 10.1038/s41467-024-46371-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10928157/
  15. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    3
    1. scibot 15 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.ccell.2024.02.016

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    2. scibot 15 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.ccell.2024.02.016

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    3. scibot 15 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.ccell.2024.02.016

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    sciencedirect.com/science/article/pii/S1535610824000606
  16. www.sciencedirect.com www.sciencedirect.com
    NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment
    2
    1. scibot 06 Mar 2024
      Plasmid_12371

      DOI: 10.1016/j.celrep.2024.113898

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    2. scibot 06 Mar 2024
      Plasmid_12371

      DOI: 10.1016/j.celrep.2024.113898

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    sciencedirect.com/science/article/pii/S2211124724002262
  17. Feb 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
    2
    1. scibot 21 Feb 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.113796

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    2. scibot 21 Feb 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.113796

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    sciencedirect.com/science/article/pii/S2211124724001244
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy
    1
    1. scibot 05 Feb 2024
      12371

      DOI: 10.1101/2024.01.07.574553

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802410/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells
    1
    1. scibot 01 Feb 2024
      12371

      DOI: 10.1038/s41467-024-44885-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798966/
  21. Jan 2024
  22. www.nature.com www.nature.com
    CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity
    1
    1. scibot 20 Jan 2024
      RRID:Addgene_12371

      DOI: 10.1038/s41423-024-01124-2

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    nature.com/articles/s41423-024-01124-2
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Highly cooperative chimeric super-SOX induces naive pluripotency across species
    1
    1. scibot 23 Dec 2023
      Addgene_12371

      DOI: 10.1016/j.stem.2023.11.010

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    sciencedirect.com/science/article/pii/S1934590923004022
  25. www.sciencedirect.com www.sciencedirect.com
    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2023.113452

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    sciencedirect.com/science/article/pii/S221112472301464X
  26. Nov 2023
  27. www.biorxiv.org www.biorxiv.org
    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
    1
    1. scibot 17 Nov 2023
      Addgene_12371

      DOI: 10.1101/2023.11.06.565713

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    biorxiv.org/content/10.1101/2023.11.06.565713v1
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
    1
    1. scibot 27 Oct 2023
      plasmid_12371

      DOI: 10.1016/j.yexcr.2023.113820

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    sciencedirect.com/science/article/pii/S0014482723003713
  30. 52.53.155.43 52.53.155.43
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 20 Oct 2023
      RRID:Addgene_12371

      DOI: 10.1101/2023.09.04.556230

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    52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
  31. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
    2
    1. scibot 13 Oct 2023
      Addgene_12371

      DOI: 10.1016/j.ccell.2023.09.011

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    2. scibot 13 Oct 2023
      Addgene_12371

      DOI: 10.1016/j.ccell.2023.09.011

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    sciencedirect.com/science/article/pii/S1535610823003276
  32. Sep 2023
  33. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
    1
    1. scibot 29 Sep 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.stem.2023.07.001

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    sciencedirect.com/science/article/pii/S1934590923002461
  34. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
    1. scibot 19 Sep 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors
    1
    1. scibot 07 Sep 2023
      RRID:Addgene_12371

      DOI: 10.1158/2326-6066.CIR-22-0640

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    ncbi.nlm.nih.gov/pmc/articles/PMC10472109/
  36. www.sciencedirect.com www.sciencedirect.com
    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
    2
    1. scibot 01 Sep 2023
      plasmid# 12371

      DOI: 10.1016/j.celrep.2023.113047

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    2. scibot 01 Sep 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2023.113047

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    sciencedirect.com/science/article/pii/S2211124723010586
  37. Aug 2023
  38. 52.53.155.43 52.53.155.43
    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
    2
    1. scibot 18 Aug 2023
      addgene_12371

      DOI: 10.1016/j.celrep.2023.112968

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    2. scibot 16 Aug 2023
      addgene_12371

      DOI: 10.1016/j.celrep.2023.112968

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    52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
  39. Jul 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
    1
    1. scibot 21 Jul 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2023.112794

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    sciencedirect.com/science/article/pii/S2211124723008057
  41. Jun 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis
    1
    1. scibot 02 Jun 2023
      Addgene_12371

      DOI: 10.1016/j.stem.2023.05.002

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    sciencedirect.com/science/article/pii/S1934590923001728
  43. May 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional requirements for a Samd14-capping protein complex in stress erythropoiesis
    1
    1. scibot 05 May 2023
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      DOI: 10.7554/eLife.76497

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    ncbi.nlm.nih.gov/pmc/articles/PMC9282853/
  45. Apr 2023
  46. www.biorxiv.org www.biorxiv.org
    Molecular, metabolic and functional CD4 T cell paralysis impedes tumor control
    1
    1. scibot 21 Apr 2023
      RRID:Addgene_12371

      DOI: 10.1101/2023.04.15.536946

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    biorxiv.org/content/10.1101/2023.04.15.536946v1
  47. www.biorxiv.org www.biorxiv.org
    Inducing an oxidized redox-balance improves anti-tumor CD8+ T cell function
    1
    1. scibot 20 Apr 2023
      RRID:Addgene_12371

      DOI: 10.1101/2023.03.27.533229

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    biorxiv.org/content/10.1101/2023.03.27.533229v1
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel role of pre-replication complex component cell division cycle 6 in retinal neovascularization
    1
    1. scibot 04 Apr 2023
      RRID:Addgene_12371

      DOI: 10.1161/ATVBAHA.121.317182

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    ncbi.nlm.nih.gov/pmc/articles/PMC8957605/
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
    1
    1. scibot 28 Jan 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.immuni.2022.12.007

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    sciencedirect.com/science/article/pii/S1074761322006434
  51. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
    1
    1. scibot 06 Jan 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.stem.2022.12.006

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    sciencedirect.com/science/article/pii/S1934590922004908
  52. Dec 2022
  53. academic.oup.com academic.oup.com
    Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing
    1
    1. scibot 13 Dec 2022
      RRID:Addgene_12371

      DOI: 10.1093/narcan/zcac039

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    academic.oup.com/narcancer/article/4/4/zcac039/6884716
  54. Nov 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis
    1
    1. scibot 24 Nov 2022
      Plasmid_12371

      DOI: 10.1016/j.celrep.2022.111687

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    sciencedirect.com/science/article/pii/S2211124722015613
  56. Oct 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
    1
    1. scibot 26 Oct 2022
      RRID:Addgene_12371

      DOI: 10.1016/j.isci.2022.105233

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  58. Aug 2022
  59. www.sciencedirect.com www.sciencedirect.com
    METTL14-dependent m6A modification controls iNKT cell development and function
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      Addgene: 12371

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    sciencedirect.com/science/article/pii/S2211124722009652
  60. Jul 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
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      Addgenecat. 12371

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  62. www.sciencedirect.com www.sciencedirect.com
    Generation of hematopoietic lineage cell-specific chimeric mice using retrovirus-transduced fetal liver cells
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      RRID:Addgene_12371

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  63. Apr 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of CDK4/6 promotes CD8 T cell memory formation
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      RRID:Addgene_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC8487897/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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  66. Mar 2022
  67. www.sciencedirect.com www.sciencedirect.com
    Capybara: A computational tool to measure cell identity and fate transitions
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      RRID:Addgene_12371

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  68. www.sciencedirect.com www.sciencedirect.com
    Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis
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      RRID:Addgene_12371

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    RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
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      AddgeneCat#: 12371

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  70. www.sciencedirect.com www.sciencedirect.com
    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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  71. Feb 2022
  72. www.sciencedirect.com www.sciencedirect.com
    The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
    2
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  73. www.sciencedirect.com www.sciencedirect.com
    An oncogenic enhancer encodes selective selenium dependency in AML
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  74. Jan 2022
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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  76. Dec 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2211124721015746
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    Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning
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  79. Sep 2021
  80. www.sciencedirect.com www.sciencedirect.com
    PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure
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      RRID:Addgene_12371

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    sciencedirect.com/science/article/pii/S2211124721011165
  81. Jul 2021
  82. www.biorxiv.org www.biorxiv.org
    MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
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      plasmid_12371

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    biorxiv.org/content/10.1101/107201v1
  83. www.sciencedirect.com www.sciencedirect.com
    Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA
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      Addgene # 12371

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    sciencedirect.com/science/article/pii/S0092867419301126
  84. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1550413118306909
  85. Jun 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome
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    sciencedirect.com/science/article/pii/S2211124721006975
  87. www.sciencedirect.com www.sciencedirect.com
    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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      RRID:Addgene_12371

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    sciencedirect.com/science/article/pii/S2211124721005635
  88. May 2021
  89. www.mdpi.com www.mdpi.com
    The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
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      RRID:Addgene_12371

      DOI: 10.3390/cells10051233

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    mdpi.com/2073-4409/10/5/1233
  90. www.sciencedirect.com www.sciencedirect.com
    PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay
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    1. scibot 14 May 2021
      Addgene plasmid Cat # 12371

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    sciencedirect.com/science/article/pii/S1534580721003579
  91. Mar 2021
  92. www.sciencedirect.com www.sciencedirect.com
    Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
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      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2021.108833

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    sciencedirect.com/science/article/pii/S2211124721001479
  93. Feb 2021
  94. www.sciencedirect.com www.sciencedirect.com
    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_12371

      DOI: 10.1016/j.immuni.2020.12.010

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    sciencedirect.com/science/article/pii/S1074761320305380
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
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      RRID:Addgene_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC7341821/
  96. Oct 2020
  97. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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  98. Sep 2020
  99. www.sciencedirect.com www.sciencedirect.com
    Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
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      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2020.107604

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  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
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      RRID:Addgene_12371

      DOI: 10.1016/j.xcrm.2020.100074

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation
    1
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      RRID:Addgene_12371

      DOI: 10.3892/mmr.2019.10849

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    ncbi.nlm.nih.gov/pmc/articles/PMC6947934/
  102. www.sciencedirect.com www.sciencedirect.com
    Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
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    1. scibot 03 Sep 2020
      Addgene plasmidCat# 12371

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  103. Jan 2020
  104. www.sciencedirect.com www.sciencedirect.com
    53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_12371

      DOI: 10.1016/j.molcel.2019.09.024

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    sciencedirect.com/science/article/pii/S1097276519307294
  105. www.sciencedirect.com www.sciencedirect.com
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      plasmid_12371

      DOI: 10.1016/j.celrep.2018.11.101

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    sciencedirect.com/science/article/pii/S2211124718319077