109 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OH2 oncolytic virus inhibits non-small-cell lung cancer metastasis via β-catenin pathway suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12304221/
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PKA-Mediated Phosphorylation of SFRP4 Promotes Wnt/β-Catenin Activation and Cancer Stemness in Gastric Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12192866/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI
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    pmc.ncbi.nlm.nih.gov/articles/PMC12229708/
  6. Jun 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12182866/
  8. www.nature.com www.nature.com
    Blocking the functional domain of cancer cell surface TIP1 upregulates Midkine via the β-catenin/Wnt signaling pathway
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    nature.com/articles/s41417-025-00922-8
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12095580/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WNT-induced association of Frizzled and LRP6 is not sufficient for the initiation of WNT/β-catenin signaling
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12103576/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions Using NanoBit/BRET
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12153800/
  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045047/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Complex G-protein signaling of the adhesion GPCR, ADGRA3
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    pmc.ncbi.nlm.nih.gov/articles/PMC12059339/
  15. Apr 2025
  16. www.sciencedirect.com www.sciencedirect.com
    KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway
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    sciencedirect.com/science/article/pii/S2211124725003663
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
  18. Mar 2025
  19. www.sciencedirect.com www.sciencedirect.com
    A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies
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    sciencedirect.com/science/article/pii/S1535610825001084
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FoxO3 controls cardiomyocyte proliferation and heart regeneration by regulating Sfrp2 expression in postnatal mice
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11909131/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225002160-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904601/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PGK1 enhances productive bovine herpesvirus 1 infection by stimulating β-catenin-dependent transcription
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11887390/
  23. Jan 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo design of peptide binders to conformationally diverse targets with contrastive language modeling
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11753435/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695814/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695057/
  27. Dec 2024
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional and Biological Characterization of the LGR5Δ5 Splice Variant in HEK293T Cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11678308/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11666238/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11649413/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Methylation-modulated PFTK1 regulates gefitinib resistance via Wnt/β-catenin signaling in EGFR mutant non-small-cell lung cancer cells
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11659392/
  32. Sep 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of frizzled 7 activation and allosteric regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358414/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA Methylation in Recurrent Glioblastomas: Increased TEM8 Expression Activates the Src/PI3K/AKT/GSK-3β/Β-Catenin Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11363927/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics analyses reveal aberrant differentiation trajectory with WNT1 loss-of-function in type XV osteogenesis imperfecta
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    ncbi.nlm.nih.gov/pmc/articles/PMC11371906/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM59 is required for mouse GC-1 cell maintenance through modulating the ubiquitination of AXIN1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387378/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of zinc finger MIZ-type containing 2 as an oncoprotein enhancing NAD-dependent protein deacetylase sirtuin-1 deacetylase activity to regulate Wnt and Hippo pathways in non-small-cell lung cancer
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11391738/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic analysis of the developing mammalian brain links PCDH19 to the Wnt/β-catenin signalling pathway
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11408250/
  39. Aug 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291000/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β‐catenin Signaling via Epigenetic Dysregulation that Enhances Sp1‐β catenin‐p300 Interactions in Hepatocellular Carcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11304255/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11277537/
  43. Jul 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10120075/
  45. www.sciencedirect.com www.sciencedirect.com
    Ultra-large Scale Virtual Screening Identifies a Small Molecule Inhibitor of the Wnt transporter WLS
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    sciencedirect.com/science/article/pii/S2589004224016791
  46. Jun 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin mRNA encapsulated in SM-102 lipid nanoparticles enhances bone formation in a murine tibia fracture repair model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145078/
  48. www.sciencedirect.com www.sciencedirect.com
    Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos
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    sciencedirect.com/science/article/pii/S2405844024082744
  49. May 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11091678/
  51. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
    1
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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  52. Apr 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11055877/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016227/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Competence for neural crest induction is controlled by hydrostatic pressure through Yap
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11021196/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transport of CLCA2 to the nucleus by extracellular vesicles controls keratinocyte survival and migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11007793/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11004431/
  58. Mar 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10933437/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The co-receptor Tspan12 directly captures Norrin to promote ligand-specific β-catenin signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10862866/
  61. Feb 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and tankyrase
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10862876/
  63. www.biorxiv.org www.biorxiv.org
    The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis Genes
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    biorxiv.org/content/10.1101/2023.12.18.571901v1
  64. www.sciencedirect.com www.sciencedirect.com
    Quantitative and qualitative mutational impact of ionizing radiation on normal cells
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    sciencedirect.com/science/article/pii/S2666979X24000260
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LASS2 enhances chemosensitivity to cisplatin by inhibiting PP2A-mediated β-catenin dephosphorylation in a subset of stem-like bladder cancer cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10775422/
  66. Jan 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Programmable RNA base editing with photoactivatable CRISPR-Cas13
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803366/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10765799/
  69. Nov 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
  71. Oct 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis
    1
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    sciencedirect.com/science/article/pii/S2589004223021521
  73. Sep 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Modulation of cell physiology by bispecific nanobodies enabling changes in the intracellular localization of organelle proteins
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    sciencedirect.com/science/article/pii/S000629522300299X
  75. Aug 2023
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aicardi Syndrome Is a Genetically Heterogeneous Disorder
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    ncbi.nlm.nih.gov/pmc/articles/PMC10454071/
  77. Jul 2023
  78. www.biorxiv.org www.biorxiv.org
    The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis
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    biorxiv.org/content/10.1101/2023.06.02.543509v2
  79. Jun 2023
  80. 52.53.155.43 52.53.155.43
    bqad096-html.html
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    52.53.155.43/a0f6dfb55e5b40d099e857f8219485820662af48/bqad096-html.html
  81. May 2023
  82. bioone.org bioone.org
    Activated Beta-Catenin Signaling Ameliorates Radiation-Induced Skin Injury by Suppressing Marvel D3 Expression
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    bioone.org/journals/radiation-research/volume-195/issue-2/RADE-20-00050.1/Activated-Beta-Catenin-Signaling-Ameliorates-Radiation-Induced-Skin-Injury-by/10.1667/RADE-20-00050.1.full
  83. Apr 2023
  84. www.biorxiv.org www.biorxiv.org
    Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer
    1
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    biorxiv.org/content/10.1101/2023.04.04.535570v1
  85. Mar 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9997973/
  87. Feb 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina
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    ncbi.nlm.nih.gov/pmc/articles/PMC9932814/
  89. Jan 2023
  90. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
    1
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    sciencedirect.com/science/article/pii/S009286742201529X
  91. Nov 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  93. Oct 2022
  94. www.nature.com www.nature.com
    DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon
    1
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    nature.com/articles/s41467-022-33844-2
  95. www.science.org www.science.org
    PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling
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    science.org/doi/10.1126/scisignal.abo2820
  96. Sep 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Genomic and phenotypic characterization of 404 individuals with neurodevelopmental disorders caused by CTNNB1 variants
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    sciencedirect.com/science/article/pii/S1098360022008978
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic control of the canonical Wnt signaling pathway during Xenopus laevis embryonic development
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    ncbi.nlm.nih.gov/pmc/articles/PMC8380706/
  99. May 2022
  100. www.sciencedirect.com www.sciencedirect.com
    5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis
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    sciencedirect.com/science/article/pii/S0896627322003695
  101. www.nature.com www.nature.com
    Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
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    nature.com/articles/s41467-022-29942-w
  102. Apr 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8987407/
  104. Mar 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    sciencedirect.com/science/article/pii/S2211124722002790
  106. www.sciencedirect.com www.sciencedirect.com
    Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases
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    sciencedirect.com/science/article/pii/S2589004222001821
  107. link.springer.com link.springer.com
    Muscle Stem Cell Function Is Impaired in β2-Adrenoceptor Knockout Mice
    2
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    link.springer.com/article/10.1007/s12015-022-10334-y
  108. Feb 2022
  109. www.sciencedirect.com www.sciencedirect.com
    Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2
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    sciencedirect.com/science/article/pii/S2211124722000304
  110. link.springer.com link.springer.com
    Competitive blocking of LRP4–sclerostin binding interface strongly promotes bone anabolic functions
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    link.springer.com/article/10.1007/s00018-022-04127-2
  111. Jan 2022
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence for a Dual-Pathway, 2-Hit Genetic Model for Focal Cortical Dysplasia and Epilepsy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8789218/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC8690924/
  114. Oct 2021
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
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    ncbi.nlm.nih.gov/pmc/articles/PMC8480975/
  116. Sep 2021
  117. www.nature.com www.nature.com
    Compact RNA editors with small Cas13 proteins
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    nature.com/articles/s41587-021-01030-2
  118. Aug 2021
  119. www.sciencedirect.com www.sciencedirect.com
    Antagonistic interactions between osterix and pyrophosphate during cementum formation
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    sciencedirect.com/science/article/pii/S8756328219301656
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes
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