14 Matching Annotations
  1. Jun 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Paired CRISPR screens identify mitochondrial metabolism and UBE2H as aneuploid-specific dependencies in human cancer cell lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC13142536/
  3. Dec 2025
  4. www.biorxiv.org www.biorxiv.org
    A clinical-stage oncology compound selectively targets drug-resistant cancers
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    biorxiv.org/content/10.1101/2025.11.26.690878v1
  5. Aug 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324462/
  7. Jun 2025
  8. www.sciencedirect.com www.sciencedirect.com
    The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867425006166
  9. May 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032731/
  11. Apr 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A ROR1 targeted bispecific T cell engager shows high potency in the pre-clinical model of triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11956192/
  13. Dec 2024
  14. www.cell.com www.cell.com
    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
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    cell.com/current-biology/abstract/S0960-9822(24)01575-6
  15. Jun 2024
  16. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867424005762
  17. May 2024
  18. link.springer.com link.springer.com
    Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
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    link.springer.com/article/10.1186/s13293-024-00618-y
  19. Mar 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GTP binding protein 2 maintains the quiescence, self-renewal, and chemoresistance of mouse colorectal cancer stem cells via promoting Wnt signaling activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926081/
  21. Oct 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
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    ncbi.nlm.nih.gov/pmc/articles/PMC9530850/
  23. Aug 2021
  24. www.sciencedirect.com www.sciencedirect.com
    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
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    sciencedirect.com/science/article/pii/S153458072100592X