13 Matching Annotations
  1. Dec 2025
  2. www.biorxiv.org www.biorxiv.org
    A clinical-stage oncology compound selectively targets drug-resistant cancers
    2
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    biorxiv.org/content/10.1101/2025.11.26.690878v1
  3. Aug 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324462/
  5. Jun 2025
  6. www.sciencedirect.com www.sciencedirect.com
    The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
    1
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    sciencedirect.com/science/article/pii/S0092867425006166
  7. May 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032731/
  9. Apr 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A ROR1 targeted bispecific T cell engager shows high potency in the pre-clinical model of triple negative breast cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11956192/
  11. Dec 2024
  12. www.cell.com www.cell.com
    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
    1
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    cell.com/current-biology/abstract/S0960-9822(24)01575-6
  13. Jun 2024
  14. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
    1
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    sciencedirect.com/science/article/pii/S0092867424005762
  15. May 2024
  16. link.springer.com link.springer.com
    Sex- and species-specific contribution of CD99 to T cell costimulation during multiple sclerosis
    1
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    link.springer.com/article/10.1186/s13293-024-00618-y
  17. Mar 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GTP binding protein 2 maintains the quiescence, self-renewal, and chemoresistance of mouse colorectal cancer stem cells via promoting Wnt signaling activation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926081/
  19. Oct 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9530850/
  21. Aug 2021
  22. www.sciencedirect.com www.sciencedirect.com
    Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
    1
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    sciencedirect.com/science/article/pii/S153458072100592X