39 Matching Annotations
  1. Last 7 days
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    MTAP loss upregulates BCAT1 in pancreatic cancer and drives branched-chain amino acid dependency
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    sciencedirect.com/science/article/pii/S2211124726011241
  3. Jun 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of circulating glycocholic acid-regulated signaling potentiates immune checkpoint therapy in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13230736/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potassium suppresses allosteric activation of ZAP-70-dependent T cell receptor signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13235457/
  6. May 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DHODH-Mediated Suppression of Ferroptosis Supports Radioresistance and Represents a Therapeutic Vulnerability in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179828/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133602/
  9. Apr 2026
  10. www.science.org www.science.org
    Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer
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    science.org/doi/10.1126/sciimmunol.adt7832
  11. Feb 2026
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    Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors
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    sciencedirect.com/science/article/pii/S2666379125006184
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ASS1 facilitates T-ALL progression via the arginine-mediated mTORC1/c-Myc signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12706054/
  14. Nov 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role and mechanism of ubiquitin-specific protease 35 in ferroptosis of rheumatoid arthritis-fibroblast like synoviocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12549345/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oligomeric cystatin C supports the immunosuppressive activity of myeloid cells through interaction with inhibitory receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615798/
  17. Oct 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    XXYLT1 inhibits NOTCH1 activation in Jurkat cells while promoting cell proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12549121/
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    A nanobody-based tri-specific NK cell engager targeting CD5 triggers antitumor immunity
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    sciencedirect.com/science/article/pii/S2666379125004823
  20. Sep 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JNK kinase regulates phosphorylation of HCoV-229E nucleocapsid protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12446446/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oxidative Phosphorylation is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11908958/
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    Genetically encoded FerriTag as a specific label for cryo-electron tomography
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    sciencedirect.com/science/article/pii/S096921262500317X
  24. Aug 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Translation efficiency covariation identifies conserved coordination patterns across cell types
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    pmc.ncbi.nlm.nih.gov/articles/PMC12329774/
  26. Jul 2025
  27. aacrjournals.org aacrjournals.org
    TFE3-splicing factor fusions represent functional drivers and druggable targets in translocation renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/8/1286/742985/TFE3-Splicing-Factor-Fusions-Represent-Functional
  28. Jun 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12095776/
  30. May 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032206/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12003641/
  33. Feb 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11801721/
  35. Nov 2024
  36. www.biorxiv.org www.biorxiv.org
    Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation
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    biorxiv.org/content/10.1101/2024.09.26.615177v1
  37. Sep 2024
  38. www.biorxiv.org www.biorxiv.org
    Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography
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    biorxiv.org/content/10.1101/2024.09.10.612178v1
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    sciencedirect.com/science/article/pii/S1534580724004921
  40. Aug 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cathepsin L induces cellular senescence by upregulating CUX1 and p16INK4a
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    ncbi.nlm.nih.gov/pmc/articles/PMC11272106/
  42. Jun 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11165854/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic protein circuits for programmable control of mammalian cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127782/
  45. May 2024
  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    pubmed.ncbi.nlm.nih.gov/38330145/
  47. Apr 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
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    sciencedirect.com/science/article/pii/S0092867424003131
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    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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    nature.com/articles/s41467-024-47069-y
  50. Mar 2024
  51. www.nature.com www.nature.com
    GAS41 modulates ferroptosis by anchoring NRF2 on chromatin
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    nature.com/articles/s41467-024-46857-w
  52. Feb 2024
  53. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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    sciencedirect.com/science/article/pii/S1550413124000056
  54. Jun 2023
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    sciencedirect.com/science/article/pii/S2211124723006277
  56. Apr 2023
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    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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    sciencedirect.com/science/article/pii/S1535610823000508
  58. May 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
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    sciencedirect.com/science/article/pii/S2352396422002419
  60. Jun 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8193145/