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Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual targeting of CDK4/6 and CDK7 augments tumor response and antitumor immunity in breast cancer models

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1. scibot 23 Nov 2025
  
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  126679
  
  DOI: 10.1172/JCI188839
  
  Resource: RRID:Addgene_126679
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_126679
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12520673/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer

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1. scibot 23 Nov 2025
  
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  126679
  
  DOI: 10.1101/2024.11.11.623139
  
  Resource: RRID:Addgene_126679
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_126679
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11601343/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

E2F activity determines mitosis versus whole-genome duplication in G2-arrested cells

1
1. scibot 11 Aug 2025
  
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  126679
  
  DOI: 10.1038/s41467-025-62061-w
  
  Resource: RRID:Addgene_126679
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12279939/
Jul 2025
www.embopress.org www.embopress.org

Oncogenic YAP sensitizes cells to CHK1 inhibition via CDK4/6 driven G1 acceleration | EMBO reports

1
1. scibot 08 Jul 2025
  
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  RRID:Addgene_126679
  
  DOI: 10.1038/s44319-025-00514-5
  
  Resource: RRID:Addgene_126679
  
  Curator: @dhovakimyan1
  
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embopress.org/doi/full/10.1038/s44319-025-00514-5
www.embopress.org www.embopress.org

Oncogenic YAP sensitizes cells to CHK1 inhibition via CDK4/6 driven G1 acceleration

1
1. scibot 08 Jul 2025
  
  in Public
  
  RRID:Addgene_126679
  
  DOI: 10.1038/s44319-025-00514-5
  
  Resource: RRID:Addgene_126679
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_126679
  
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embopress.org/doi/10.1038/s44319-025-00514-5
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication

2
1. scibot 20 Apr 2024
  
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  Addgene Cat# 126679
  
  DOI: 10.1016/j.devcel.2024.03.032
  
  Resource: RRID:Addgene_126679
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_126679
  
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2. scibot 20 Apr 2024
  
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  Addgene_126679
  
  DOI: 10.1016/j.devcel.2024.03.032
  
  Resource: RRID:Addgene_126679
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_126679
  
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sciencedirect.com/science/article/pii/S1534580724002004
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer

1
1. scibot 27 Oct 2023
  
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  RRID:Addgene_126679
  
  DOI: 10.1016/j.celrep.2023.113198
  
  Resource: RRID:Addgene_126679
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S221112472301210X
May 2023
www.sciencedirect.com www.sciencedirect.com

Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma

1
1. scibot 31 May 2023
  
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  Plasmid_126679
  
  DOI: 10.1016/j.celrep.2023.112570
  
  Resource: RRID:Addgene_126679
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_126679
  
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sciencedirect.com/science/article/pii/S2211124723005818