31 Matching Annotations
  1. Last 7 days
  2. www.nature.com www.nature.com
    SINE compounds activate exportin 1 degradation through an allosteric mechanism
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    nature.com/articles/s41589-025-02058-0
  3. Sep 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation
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    sciencedirect.com/science/article/pii/S2211124725010575
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KCTD10 inhibits lung cancer metastasis and angiogenesis via ubiquitin-mediated β-catenin degradation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12378768/
  6. Aug 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283023/
  8. Jul 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    African swine fever virus MGF505-4R facilitates cGAS degradation through TOLLIP-mediated selective autophagy and inhibits the formation of ISGF3 to evade innate immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12228400/
  10. Jun 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
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    sciencedirect.com/science/article/pii/S1074761325002328
  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Irisin protects against cerebral ischemia reperfusion injury in a SIRT3-dependent manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC11996646/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1,4‐Dioxane Induces Epithelial‐Mesenchymal Transition and Carcinogenesis in an Nrf2‐Dependent Manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC12042698/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VDAC2 loss elicits tumour destruction and inflammation for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12018455/
  16. Jan 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tp53 determines the spatial dynamics of M1/M2 tumor-associated macrophages and M1-driven tumoricidal effects
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    pmc.ncbi.nlm.nih.gov/articles/PMC11754596/
  18. Nov 2024
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies
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    onlinelibrary.wiley.com/doi/full/10.1002/advs.202404109
  20. Sep 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Digital spatial profiling identifies the tumor center as a topological niche in prostate cancer characterized by an upregulation of BAD
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366015/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of MxA in esophageal cancer cell lines can influence sensitivity to chemotherapeutic agents but this does not require apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405456/
  23. www.sciencedirect.com www.sciencedirect.com
    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    sciencedirect.com/science/article/pii/S1534580724004921
  24. Aug 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11339396/
  26. Jun 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189633/
  28. May 2024
  29. aacrjournals.org aacrjournals.org
    TNFRSF19 within the 13q12.12 risk locus functions as a lung cancer suppressor by binding Wnt3a to inhibit Wnt/β-catenin signaling.
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    aacrjournals.org/mcr/article/22/3/227/734703/TNFRSF19-within-the-13q12-12-Risk-Locus-Functions
  30. Feb 2024
  31. 52.53.155.43 52.53.155.43
    d4-html.html
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    52.53.155.43/f092aa63506937030df3074397696edbfe46ccc6/d4-html.html
  32. Jan 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of VHL by VH298 Accelerates Pexophagy by Activation of HIF-1α in HeLa Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10819186/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10754148/
  35. Sep 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10470315/
  37. www.sciencedirect.com www.sciencedirect.com
    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
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    sciencedirect.com/science/article/pii/S2211124723010537
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone
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    sciencedirect.com/science/article/pii/S2211124723003820
  40. Mar 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9949130/
  42. Dec 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
  44. Sep 2021
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8423903/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis to Identify Enhancer-Regulated Inflammation-Associated Genes in Lung Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8445607/
  47. Mar 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MicroRNA-383 promotes reactive oxygen species-induced autophagy via downregulating peroxiredoxin 3 in human glioma U87 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7967820/
  49. Sep 2020
  50. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Low HOXC10 expression in liver cancer regulates proliferation via a mechanism involving miR-221 and the MAPK signaling pathway
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    pubmed.ncbi.nlm.nih.gov/32934696/