26 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T4 DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR editing
    1
    1. scibot 28 Sep 2024
      plasmid_132775

      DOI: 10.1038/s44318-024-00158-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11377749/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precise Insertion of AttB Sequences in Goat Genome Using Enhanced Prime Editor
    1
    1. scibot 25 Sep 2024
      132775

      DOI: 10.3390/ijms25179486

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      Curator: @olekpark

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    ncbi.nlm.nih.gov/pmc/articles/PMC11395042/
  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and testing of a versatile genome editing application reporter (V-GEAR) system
    1
    1. scibot 21 Jun 2024
      132775

      DOI: 10.1016/j.omtm.2024.101253

      Resource: RRID:Addgene_132775

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    ncbi.nlm.nih.gov/pmc/articles/PMC11101715/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line
    1
    1. scibot 06 Jun 2024
      Addgene_132775

      DOI: 10.1111/cas.16162

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145152/
  7. May 2024
  8. www.biorxiv.org www.biorxiv.org
    Enrichment of allelic editing outcomes by Prime Editing in iPS cells
    1
    1. scibot 29 May 2024
      RRID; Addgene_132775

      DOI: 10.1101/2024.03.19.585665

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      Curator: @abever99

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      DOI:10.1101/2024.03.19.585665 RRID:Addgene_132775
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    biorxiv.org/content/10.1101/2024.03.19.585665v1
  9. www.sciencedirect.com www.sciencedirect.com
    Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
    1
    1. scibot 02 May 2024
      Addgene: 132775

      DOI: 10.1016/j.xcrm.2024.101544

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2666379124002349
  10. Apr 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing prime editor flexibility with coiled-coil heterodimers
    1
    1. scibot 29 Apr 2024
      132775

      DOI: 10.1186/s13059-024-03257-z

      Resource: RRID:Addgene_132775

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046888/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving prime editing with an endogenous small RNA-binding protein
    1
    1. scibot 23 Apr 2024
      132775

      DOI: 10.1038/s41586-024-07259-6

      Resource: RRID:Addgene_132775

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    ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing prime editor activity by directed protein evolution in yeast
    1
    1. scibot 17 Mar 2024
      Addgene_132775

      DOI: 10.1038/s41467-024-46107-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920827/
  15. Feb 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
    1
    1. scibot 29 Feb 2024
      Addgene_132775

      DOI: 10.1089/crispr.2023.0066

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    ncbi.nlm.nih.gov/pmc/articles/PMC10880268/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing
    1
    1. scibot 21 Feb 2024
      132775

      DOI: 10.1038/s41592-023-02146-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864177/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide in-locus epitope tagging of Arabidopsis proteins using prime editors
    1
    1. scibot 04 Feb 2024
      132775

      DOI: 10.5483/BMBRep.2023-0055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10828436/
  19. Jan 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors
    1
    1. scibot 05 Jan 2024
      RRID:Addgene_132775

      DOI: 10.1089/crispr.2023.0048

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    ncbi.nlm.nih.gov/pmc/articles/PMC10753986/
  21. Dec 2023
  22. www.sciencedirect.com www.sciencedirect.com
    High-throughput PRIME-editing screens identify functional DNA variants in the human genome
    1
    1. scibot 22 Dec 2023
      Addgene plasmid# 132775

      DOI: 10.1016/j.molcel.2023.11.021

      Resource: RRID:Addgene_132775

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1097276523009668
  23. Aug 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades
    1
    1. scibot 17 Aug 2023
      RRID:Addgene_132775

      DOI: 10.1016/j.jbc.2023.105154

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    sciencedirect.com/science/article/pii/S0021925823021828
  25. May 2023
  26. www.mdpi.com www.mdpi.com
    Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations
    1
    1. scibot 25 May 2023
      RRID:Addgene_132775

      DOI: 10.3390/biom13050870

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    mdpi.com/2218-273X/13/5/870
  27. www.sciencedirect.com www.sciencedirect.com
    Systematic characterization of regulatory variants of blood pressure genes
    1
    1. scibot 25 May 2023
      Addgene_132775

      DOI: 10.1016/j.xgen.2023.100330

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    sciencedirect.com/science/article/pii/S2666979X23000988
  28. www.sciencedirect.com www.sciencedirect.com
    Generation of three CRISPR/Cas9 edited human induced pluripotent stem cell lines (DHMi005-A-5, DHMi005-A-6 and DHMi005-A-7) carrying a Holt-Oram Syndrome patient-specific TBX5 mutation with known cardiac phenotype and a FLAG-tag after exon 9 of the TBX5 gene
    1
    1. scibot 17 May 2023
      RRID:Addgene_132775

      DOI: 10.1016/j.scr.2023.103123

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    sciencedirect.com/science/article/pii/S1873506123001095
  29. academic.oup.com academic.oup.com
    Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs
    1
    1. scibot 10 May 2023
      RRID:Addgene_132775

      DOI: 10.1093/nar/gkad323

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad323/7151351
  30. Apr 2023
  31. www.biorxiv.org www.biorxiv.org
    Quantitative proteomics and phosphoproteomics of PPP2R5D variants reveal deregulation of RPS6 phosphorylation through converging signaling cascades
    1
    1. scibot 20 Apr 2023
      RRID:Addgene_132775

      DOI: 10.1101/2023.03.27.534397

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      Curator: @scibot

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    biorxiv.org/content/10.1101/2023.03.27.534397v1
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity
    1
    1. scibot 08 Apr 2023
      RRID:Addgene_132775

      DOI: 10.26508/lsa.202201767

      Resource: RRID:Addgene_132775

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    ncbi.nlm.nih.gov/pmc/articles/PMC10078952/
  33. Oct 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly efficient generation of isogenic pluripotent stem cell models using prime editing
    1
    1. scibot 25 Oct 2022
      RRID:Addgene_132775

      DOI: 10.7554/eLife.79208

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    ncbi.nlm.nih.gov/pmc/articles/PMC9584603/
  35. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
    1
    1. scibot 07 Oct 2022
      Cat#132775

      DOI: 10.1016/j.molcel.2022.09.007

      Resource: RRID:Addgene_132775

      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S1097276522008966
  36. May 2022
  37. www.nature.com www.nature.com
    Saturation variant interpretation using CRISPR prime editing
    1
    1. scibot 05 May 2022
      RRID:Addgene_132775

      DOI: 10.1038/s41587-021-01201-1

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    nature.com/articles/s41587-021-01201-1
  38. Jan 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene
    1
    1. scibot 28 Jan 2022
      RRID:Addgene_132775

      DOI: 10.1016/j.scr.2022.102691

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    sciencedirect.com/science/article/pii/S187350612200040X
  40. May 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease
    1
    1. scibot 05 May 2021
      Addgene_132775

      DOI: 10.1016/j.stem.2021.04.010

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    sciencedirect.com/science/article/pii/S1934590921001673