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Generation of RB1 knockout human embryonic stem cell lines derived from H9 using CRISPR/Cas9

1
1. scibot 13 Jan 2026
  
  in Public
  
  Addgene_135960
  
  DOI: 10.1016/j.scr.2025.103897
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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sciencedirect.com/science/article/pii/S1873506125002478
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NEXN deficiency leads to dilated cardiomyopathy in human pluripotent stem cell-derived cardiomyocytes

1
1. scibot 11 Aug 2025
  
  in Public
  
  135,960
  
  DOI: 10.1186/s13287-025-04484-2
  
  Resource: RRID:Addgene_135960
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12297802/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D/ZNF460-induced COL9A1-mediated extracellular matrix stiffness maintains the cancer stem cell pool to promote colorectal cancer progression

1
1. scibot 20 Jul 2025
  
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  135,960
  
  DOI: 10.1007/s10565-025-10053-3
  
  Resource: RRID:Addgene_135960
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12213864/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation

1
1. scibot 24 Apr 2025
  
  in Public
  
  epiCRISPR (135960
  
  DOI: 10.1080/15548627.2024.2443300
  
  Resource: RRID:Addgene_135960
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12013414/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia

1
1. scibot 05 Apr 2025
  
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  135960
  
  DOI: 10.1172/JCI184743
  
  Resource: RRID:Addgene_135960
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11957699/
Jan 2025
www.tandfonline.com www.tandfonline.com

Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation

1
1. scibot 04 Jan 2025
  
  in Public
  
  135960
  
  DOI: 10.1080/15548627.2024.2443300
  
  Resource: RRID:Addgene_135960
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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tandfonline.com/doi/full/10.1080/15548627.2024.2443300
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Mitochondrial transplantation rescues Ca2+ homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy

1
1. scibot 24 Dec 2024
  
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  AddgeneCat#135960
  
  DOI: 10.1016/j.celrep.2024.115065
  
  Resource: RRID:Addgene_135960
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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sciencedirect.com/science/article/pii/S2211124724014165
Oct 2024
www.sciencedirect.com www.sciencedirect.com

Generation of ID1/3 knockout human embryonic stem cell lines (WAe009-A-2A and WAe009-A-2B) derived from H9 using CRISPR/Cas9

1
1. scibot 02 Oct 2024
  
  in Public
  
  addgene_135960
  
  DOI: 10.1016/j.scr.2024.103569
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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sciencedirect.com/science/article/pii/S1873506124002678
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PLEKHM2 deficiency induces impaired mitochondrial clearance and elevated ROS levels in human iPSC-derived cardiomyocytes

1
1. scibot 15 Apr 2024
  
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  135960
  
  DOI: 10.1038/s41420-024-01907-6
  
  Resource: RRID:Addgene_135960
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10942999/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9

1
1. scibot 23 Dec 2023
  
  in Public
  
  addgene_135960
  
  DOI: 10.1016/j.scr.2023.103284
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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sciencedirect.com/science/article/pii/S1873506123002702
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Establishment of a human TLR4 compound heterozygous knockout hESC line (WAe009-A-N) to model toll-like receptor 4 deficiency by CRISPR/Cas9 system

1
1. scibot 03 Nov 2023
  
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  addgene_135960
  
  DOI: 10.1016/j.scr.2023.103225
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

URL

sciencedirect.com/science/article/pii/S1873506123002118
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

1
1. scibot 27 Oct 2023
  
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  RRID:Addgene_135960
  
  DOI: 10.1016/j.celrep.2023.113310
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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sciencedirect.com/science/article/pii/S2211124723013220
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Generation of a FLNA knockout hESC line (WAe009-A-P) to model cardiac valvular dysplasia using CRISPR/Cas9

1
1. scibot 05 Jul 2023
  
  in Public
  
  addgene_135960
  
  DOI: 10.1016/j.scr.2023.103162
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

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sciencedirect.com/science/article/pii/S1873506123001484
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Generation of a TRPM8 knockout hESC line (WAe009-A-A) derived from H9 using CRISPR/Cas9

1
1. scibot 09 Feb 2023
  
  in Public
  
  addgene_135960
  
  DOI: 10.1016/j.scr.2023.103040
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

URL

sciencedirect.com/science/article/pii/S1873506123000260
Oct 2021
www.sciencedirect.com www.sciencedirect.com

A CRISPR/Cas9 strategy for the generation of a FLNC knockout hESC line (WAe009-A-70) to model dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy

1
1. scibot 08 Oct 2021
  
  in Public
  
  addgene_135960
  
  DOI: 10.1016/j.scr.2021.102562
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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scibot

URL

sciencedirect.com/science/article/pii/S1873506121004098
Jul 2021
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Establishment of a KCNQ1 homozygous knockout human embryonic stem cell line by episomal vector-based CRISPR/Cas9 system

1
1. scibot 24 Jul 2021
  
  in Public
  
  Addgene_135960
  
  DOI: 10.1016/j.scr.2021.102467
  
  Resource: RRID:Addgene_135960
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_135960
  
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  RRID:Addgene_135960
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RRID:Addgene_135960

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scibot

URL

sciencedirect.com/science/article/pii/S1873506121003147