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Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways

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1. scibot 27 Mar 2026
  
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  138150
  
  DOI: 10.1038/s41467-025-67931-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12868881/
Mar 2026
www.biorxiv.org www.biorxiv.org

PRMT5 is Frequently Upregulated and a Potential Therapeutic Target in MTAP-deficient Malignant Peripheral Nerve Sheath Tumors

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1. scibot 19 Mar 2026
  
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  RRID:Addgene_138150
  
  DOI: 10.64898/2026.03.09.710638
  
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biorxiv.org/content/10.64898/2026.03.09.710638v1
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A single-cell atlas of RNA alternative splicing in the glioma-immune ecosystem

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1. scibot 19 Dec 2025
  
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  RRID:Addgene_138150
  
  DOI: 10.1186/s13059-025-03889-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12699894/
www.sciencedirect.com:5037 www.sciencedirect.com:5037

DROSHA, DICER, and damage-induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break

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1. scibot 13 Dec 2025
  
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  plasmid_138150
  
  DOI: 10.1016/j.celrep.2025.116605
  
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sciencedirect.com:5037/science/article/pii/S2211124725013774
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Impact of circPVT1 Expression on Prostate Cancer Malignancy and Tumor Growth

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1. scibot 10 Jul 2025
  
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  RRID:Addgene_138150
  
  DOI: 10.1267/ahc.25-00008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12229781/
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation

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1. scibot 19 Apr 2025
  
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  Addgene_138150
  
  DOI: 10.1016/j.ccell.2025.03.027
  
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sciencedirect.com/science/article/pii/S153561082500128X
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers

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1. scibot 16 Feb 2025
  
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  138150
  
  DOI: 10.1038/s41467-025-56568-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11825950/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision

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1. scibot 28 Dec 2024
  
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  Addgene_138150
  
  DOI: 10.1126/sciadv.adl0731
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11654686/
Jul 2024
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Efficient, specific, and combinatorial control of endogenous exon splicing with dCasRx-RBM25

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1. scibot 24 Jul 2024
  
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  Addgene_138150
  
  DOI: 10.1016/j.molcel.2024.05.028
  
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sciencedirect.com/science/article/pii/S1097276524004751
May 2024
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Lineage-specific splicing regulation of MAPT gene in the primate brain

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1. scibot 21 May 2024
  
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  Addgene76138150
  
  DOI: 10.1016/j.xgen.2024.100563
  
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2. scibot 21 May 2024
  
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  plasmid_138150
  
  DOI: 10.1016/j.xgen.2024.100563
  
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sciencedirect.com/science/article/pii/S2666979X24001290
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-dCas13d-based deep screening of proximal and distal splicing-regulatory elements

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1. scibot 12 May 2024
  
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  Addgene_138150
  
  DOI: 10.1038/s41467-024-47140-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11076525/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx

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1. scibot 23 Apr 2024
  
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  138150
  
  DOI: 10.1038/s41592-024-02190-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11009108/
Jan 2024
www.sciencedirect.com www.sciencedirect.com

PAPAS promotes differentiation of mammary epithelial cells and suppresses breast carcinogenesis

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1. scibot 11 Jan 2024
  
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  RRID:Addgene_138150
  
  DOI: 10.1016/j.celrep.2023.113644
  
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sciencedirect.com/science/article/pii/S2211124723016558
Jun 2023
www.nature.com www.nature.com

CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression

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1. scibot 06 Jun 2023
  
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  RRID:Addgene_138150
  
  DOI: 10.1038/s41467-023-38909-4
  
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nature.com/articles/s41467-023-38909-4