81 Matching Annotations
  1. Last 7 days
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    Photo-proximity labeling in live primary neurons identifies an AMPA-receptor signal transducer in homeostatic synaptic plasticity
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    sciencedirect.com:5037/science/article/pii/S2451945625003782
  3. Dec 2025
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial-Mesenchymal Transition Pathway
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    onlinelibrary.wiley.com/doi/full/10.1111/cas.70284
  5. Nov 2025
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    Deciphering the epigenetic role of KDM4A in pancreatic β-like cell differentiation from iPSCs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615240/
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    MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12454644/
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    NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC12456627/
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    Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS
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    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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  11. Oct 2025
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    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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  14. Sep 2025
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    SH2-mediated steric occlusion of the C2 domain regulates autoinhibition of SHIP1 inositol 5-phosphatase
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    biorxiv.org/content/10.1101/2025.09.02.673847v1
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    Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12376514/
  17. Aug 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An EGFR Co-Amplified and De Novo Long Noncoding RNA HELDR Promotes Glioblastoma Malignancy through KAT7-Driven Gene Programs
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    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  20. Jul 2025
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    Nectin-4 expression in upper and lower tract urothelial carcinoma: correlation with early-stage disease and prognostic relevance
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    link.springer.com/article/10.1007/s00428-025-04164-9
  22. Jun 2025
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    An integrated proteomic portrait of prostate cancer progression
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    HSF1 remodels mitochondrial biogenesis and function in cancer cells via TIMM17A
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132197/
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    Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
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    Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models
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    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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  29. May 2025
  30. 52.53.155.43 52.53.155.43
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    Perturb-tracing enables high-content screening of multi-scale 3D genome regulators
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    Genetic modulation of rare earth nanoparticle biotransformation shapes biological outcomes
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    Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
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  34. Apr 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil‐Mediated Lung Metastasis in Hepatocellular Carcinoma
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    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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  37. Mar 2025
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    Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responses
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    Suppression of the LKB1-AMPK-SLC7A11-GSH signaling pathway sensitizes NSCLC to albumin-bound paclitaxel via oxidative stress
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    PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways
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    Inhibition of triglyceride metabolism‐associated enhancers alters lipid deposition during adipocyte differentiation
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    A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
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  43. Jan 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat
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  45. Dec 2024
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    MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling
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    DNA Methylation in the CYP3A Distal Regulatory Region (DRR) Is Associated with the Expression of CYP3A5 and CYP3A7 in Human Liver Samples
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    Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability
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    A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
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  50. Nov 2024
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    Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma
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    Chromatin protein complexes involved in gene repression in lamina-associated domains
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  53. Sep 2024
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    FABP4-mediated lipid metabolism promotes TNBC progression and breast cancer stem cell activity
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    Identification of Cables1 as a critical host factor that promotes ALV-J replication via genome-wide CRISPR/Cas9 gene knockout screening
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    Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis
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  57. Aug 2024
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    Oxysterol binding protein (OSBP) contributes to hepatitis E virus replication
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    Fructose vs. glucose: modulating stem cell growth and function through sugar supplementation
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    Potential Role of APOBEC3 Family Proteins in SARS-CoV-2 Replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11281575/
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    Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells
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    CD38 restrains the activity of extracellular cGAMP in a model of multiple myeloma
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    ERK Activation by BRAFV600E suppresses mesenchymal migration and tumorigenesis by inhibiting RAC1
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  64. Jul 2024
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    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion
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  67. Jun 2024
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    Toll-like receptor 4 signaling activation domains promote CAR T cell function against solid tumors
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  69. May 2024
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    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    Catalytically distinct IDH1 mutants tune phenotype severity in tumor models
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    Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells
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    Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer
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  74. Apr 2024
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    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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  77. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    scAbsolute: measuring single-cell ploidy and replication status
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  80. Feb 2024
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical centrosome linker proteins
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    Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM
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    aacrjournals.org/clincancerres/article/30/2/283/733204/Magnetic-Resonance-Imaging-of-Iron-Metabolism-with
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    Stromal-derived MAOB promotes prostate cancer growth and progression
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    Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis
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  86. Dec 2023
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  88. Nov 2023
  89. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  90. Oct 2023
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    B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients
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    biorxiv.org/content/10.1101/2023.09.28.559936v1
  92. Jun 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zika Virus Induces Degradation of the Numb Protein Required through Embryonic Neurogenesis
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    Zika Virus Induces the Degradation of the Numb Protein that is Required through Embryonic Neurogenesis
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  95. May 2023
  96. www.biorxiv.org www.biorxiv.org
    Mechanisms controlling membrane recruitment and activation of autoinhibited SHIP1
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  97. Mar 2023
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    DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
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  99. Feb 2023
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    Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
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  101. Jan 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
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  103. Oct 2022
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    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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  105. May 2022
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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  107. Apr 2022
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  109. Mar 2022
  110. aacrjournals.org aacrjournals.org
    Conduit CAR: Redirecting CAR T-Cell Specificity with A Universal and Adaptable Bispecific Antibody Platform
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    aacrjournals.org/cancerrescommun/article/2/3/146/682301/Conduit-CAR-Redirecting-CAR-T-Cell-Specificity
  111. Sep 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy
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