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www.nature.com www.nature.com

A streamlined base editor engineering strategy to reduce bystander editing

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1. scibot 03 Sep 2025
  
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  RRID:Addgene_138491
  
  DOI: 10.1038/s41467-025-63609-6
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
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nature.com/articles/s41467-025-63609-6
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation

1
1. scibot 10 Aug 2025
  
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  138491
  
  DOI: 10.1038/s41467-025-62562-8
  
  Resource: RRID:Addgene_138491
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12325647/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic empirical evaluation of individual base editing targets: Validating therapeutic targets in USH2A and comparison of methods

1
1. scibot 16 May 2025
  
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  138491
  
  DOI: 10.1016/j.ymthe.2025.01.042
  
  Resource: RRID:Addgene_138491
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11997516/
Feb 2025
link.springer.com link.springer.com

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

1
1. scibot 07 Feb 2025
  
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  RRID:Addgene_138491
  
  DOI: 10.1038/s41467-025-56725-w
  
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link.springer.com/article/10.1038/s41467-025-56725-w
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Systematic identification of pathogenic variants of non-small cell lung cancer in the promoters of DNA-damage repair genes

1
1. scibot 06 Dec 2024
  
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  RRID:Addgene_138491
  
  DOI: 10.1016/j.ebiom.2024.105480
  
  Resource: RRID:Addgene_138491
  
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sciencedirect.com/science/article/pii/S2352396424005164
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Engineering Oncogenic Hotspot Mutations on SF3B1 via CRISPR-Directed PRECIS Mutagenesis

1
1. scibot 27 Sep 2024
  
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  NG-ABE8e
  
  DOI: 10.1158/2767-9764.CRC-24-0145
  
  Resource: RRID:Addgene_138491
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11421219/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

1
1. scibot 18 Aug 2024
  
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  138491
  
  DOI: 10.24272/j.issn.2095-8137.2024.090
  
  Resource: RRID:Addgene_138491
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11298667/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Development and testing of a versatile genome editing application reporter (V-GEAR) system

1
1. scibot 21 Jun 2024
  
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  Addgene_138491
  
  DOI: 10.1016/j.omtm.2024.101253
  
  Resource: RRID:Addgene_138491
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101715/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations

1
1. scibot 29 Jul 2023
  
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  plasmid_138491
  
  DOI: 10.1016/j.celrep.2023.112840
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723008513
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

1
1. scibot 23 Mar 2023
  
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  Plasmid_138491
  
  DOI: 10.1016/j.cell.2023.02.027
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0092867423001708
Dec 2022
aacrjournals.org aacrjournals.org

Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing

1
1. scibot 24 Dec 2022
  
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  RRID:Addgene_138491
  
  DOI: 10.1158/0008-5472.CAN-21-2519
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
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aacrjournals.org/cancerres/article/82/17/3002/708290/Efficient-Correction-of-Oncogenic-KRAS-and-TP53
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations

1
1. scibot 15 Mar 2022
  
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  RRID:Addgene_138491
  
  DOI: 10.3390/cells11050854
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8909053/
May 2021
www.sciencedirect.com www.sciencedirect.com

Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease

1
1. scibot 05 May 2021
  
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  Addgene_138491
  
  DOI: 10.1016/j.stem.2021.04.010
  
  Resource: RRID:Addgene_138491
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_138491
  
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  RRID:Addgene_138491
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sciencedirect.com/science/article/pii/S1934590921001673