114 Matching Annotations
  1. Sep 2026
  2. www.science.org www.science.org
    A high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways ex vivo and in vivo
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    science.org/doi/10.1126/sciadv.aec0722
  3. www.nature.com www.nature.com
    Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation
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    nature.com/articles/s41418-026-01848-w
  4. Aug 2026
  5. www.sciencedirect.com www.sciencedirect.com
    Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction
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    sciencedirect.com/science/article/pii/S0896627326005775
  6. Jun 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel tissue mechanics-guided cellular flows drive the formation of feather follicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC13226717/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rad23b exacerbates pathological aggregates through disrupting proteasome functions in Spinocerebellar ataxia type 3
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    pmc.ncbi.nlm.nih.gov/articles/PMC13224077/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE is a presynaptic protein that accumulates with age and modulates neurotransmitter release
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131475/
  10. Apr 2026
  11. www.sciencedirect.com www.sciencedirect.com
    Directed evolution of APOX for proximity labeling using phenols with high redox potentials
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    sciencedirect.com/science/article/pii/S2451945626001030
  12. www.biorxiv.org www.biorxiv.org
    Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer’s disease
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    biorxiv.org/content/10.64898/2026.03.14.711835v1
  13. Mar 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12997311/
  15. Nov 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and Application of a CAFLUX HepG2 Reporter Cell Line for Real-Time Monitoring of AhR-Mediated CYP1A1 Gene Expression in Response to Environmental Toxicants and Bioactive Modulators
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    pmc.ncbi.nlm.nih.gov/articles/PMC12564245/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11761749/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimized pipeline and designer cells for synthetic-biology-based high-throughput screening of viral protease inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12461586/
  19. Sep 2025
  20. www.biorxiv.org www.biorxiv.org
    The axonal ER couples translation and secretion machineries for local delivery of axonal transmembrane proteins to promote axonal development
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    biorxiv.org/content/10.1101/2025.09.09.674816v1
  21. www.sciencedirect.com www.sciencedirect.com
    Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1
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    sciencedirect.com/science/article/pii/S221112472501037X
  22. www.sciencedirect.com www.sciencedirect.com
    Disrupting the interaction between androgen receptor and its coregulator WDR77 delays the growth of treatment-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S221112472501006X
  23. Jul 2025
  24. www.biorxiv.org www.biorxiv.org
    A novel, high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways ex vivo and in vivo
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    biorxiv.org/content/10.1101/2025.07.22.666069v1
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of gene duplication and paralog specialisation in the evolution of the mammalian PRPS complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238573/
  26. Jun 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation-induced SUMOylation promotes Ulk4 condensation at the ciliary tip to transduce Hedgehog signal
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148026/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Harnessing endogenous miRNA targeting ZIKV: A cutting-edge strategy to inhibit virus infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC12155756/
  30. May 2025
  31. www.sciencedirect.com www.sciencedirect.com
    Two waves of adipogenesis in developing avian skin and dermal plasticity
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    sciencedirect.com/science/article/pii/S0012160625001423
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lineage-specific CDK activity dynamics characterize early mammalian development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12070373/
  33. Mar 2025
  34. www.sciencedirect.com www.sciencedirect.com
    m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice
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    sciencedirect.com/science/article/pii/S1934590925000797
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The PST repeat region of MDC1 is a tunable multivalent chromatin tethering domain
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    pmc.ncbi.nlm.nih.gov/articles/PMC11761366/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11882444/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The essential clathrin adapter protein complex-2 is tumor suppressive specifically in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11885535/
  38. Feb 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GEVSod2 Powder: A Modified Product Based on Biovesicles Functioned in Air Pollution PM2.5-Induced Cardiopulmonary Injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC11822167/
  40. Jan 2025
  41. www.nature.com www.nature.com
    Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
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    nature.com/articles/s41467-025-56282-2
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proximity based proteomics reveals Git1 as a regulator of Smoothened signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11741329/
  43. www.sciencedirect.com www.sciencedirect.com
    OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING
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    sciencedirect.com/science/article/pii/S1368764625000032
  44. Dec 2024
  45. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/e965e8c267bcac477ace8b0fa7455c4f20806539/PDF-html.html
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification and development of TRPM4 antagonists to counteract neuronal excitotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11648915/
  47. Nov 2024
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of synapse density by Pumilio RNA-binding proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC11544588/
  49. www.biorxiv.org www.biorxiv.org
    Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model
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    biorxiv.org/content/10.1101/2024.11.07.622127v1
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11513877/
  51. Sep 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Light-gated integrator for highlighting kinase activity in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11379911/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New ZNHIT3 Variants Disrupting snoRNP Assembly Cause Prenatal PEHO Syndrome with Isolated Hydrops
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383450/
  54. Aug 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deafness causing neuroplastin missense variants fail to promote plasma membrane Ca2+-ATPase levels and Ca2+ transient regulation in brain neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11264175/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Alzheimer’s disease–linked protease BACE2 cleaves VEGFR3 and modulates its signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11324312/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arl2 GTPase associates with the centrosomal protein Cdk5rap2 to regulate cortical development via microtubule organization
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321591/
  58. Jul 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2+
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    ncbi.nlm.nih.gov/pmc/articles/PMC7260201/
  60. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  61. Jun 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYCT1 controls environmental sensing in human haematopoietic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11168926/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160455/
  64. www.biorxiv.org www.biorxiv.org
    Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
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    biorxiv.org/content/10.1101/2024.05.30.596755v1
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11143359/
  66. May 2024
  67. www.biorxiv.org www.biorxiv.org
    Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons
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    biorxiv.org/content/10.1101/2024.05.16.594502v1
  68. www.sciencedirect.com www.sciencedirect.com
    Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
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    sciencedirect.com/science/article/pii/S1934590924001462
  69. Apr 2024
  70. www.sciencedirect.com www.sciencedirect.com
    Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
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    sciencedirect.com/science/article/pii/S1074761324002061
  71. www.sciencedirect.com www.sciencedirect.com
    Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program
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    sciencedirect.com/science/article/pii/S0092867424003489
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The response of Dual-leucine zipper kinase (DLK) to nocodazole: Evidence for a homeostatic cytoskeletal repair mechanism
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    ncbi.nlm.nih.gov/pmc/articles/PMC10994325/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Light-gated Integrator for Highlighting Kinase Activity in Living Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983958/
  74. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
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    sciencedirect.com/science/article/pii/S0092867424003064
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10975915/
  76. Feb 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Protocol for the isolation of GFP-expressing ferroptosis-dependent extracellular vesicles in in vitro cell culture models
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    sciencedirect.com/science/article/pii/S2666166724000571
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857481/
  79. www.sciencedirect.com www.sciencedirect.com
    In vivo imaging in transgenic songbirds reveals superdiffusive neuron migration in the adult brain
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    sciencedirect.com/science/article/pii/S221112472400086X
  80. www.sciencedirect.com www.sciencedirect.com
    Glia trigger endocytic clearance of axonal proteins to promote rodent myelination
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    sciencedirect.com/science/article/pii/S1534580724000285
  81. Jan 2024
  82. www.jneurosci.org www.jneurosci.org
    Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion
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    jneurosci.org/content/43/9/1475
  83. www.nature.com www.nature.com
    The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation
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    nature.com/articles/s41467-023-44414-5
  84. www.sciencedirect.com www.sciencedirect.com
    A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
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    sciencedirect.com/science/article/pii/S0092867423013223
  85. Nov 2023
  86. www.sciencedirect.com www.sciencedirect.com
    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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    sciencedirect.com/science/article/pii/S0092867423010838
  87. Oct 2023
  88. www.sciencedirect.com www.sciencedirect.com
    Abl2 repairs microtubules and phase separates with tubulin to promote microtubule nucleation
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    sciencedirect.com/science/article/pii/S0960982223012344
  89. www.sciencedirect.com www.sciencedirect.com
    Human pallial MGE-type GABAergic interneuron cell therapy for chronic focal epilepsy
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    sciencedirect.com/science/article/pii/S1934590923002965
  90. Aug 2023
  91. 52.53.155.43 52.53.155.43
    2023.08.11.551903v1.full-html.html
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    52.53.155.43/a10c1fc52e69e7b592bc8df66133ffbdae0f07d6/2023.08.11.551903v1.full-html.html
  92. www.sciencedirect.com www.sciencedirect.com
    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0896627323005135
  93. May 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10175236/
  95. Feb 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC9894587/
  97. Nov 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niraparib-induced STAT3 inhibition increases its antitumor effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC9618811/
  99. Oct 2022
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  101. May 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC9089756/
  103. Feb 2022
  104. www.nature.com www.nature.com
    Characterization of the canine CD20 as a therapeutic target for comparative passive immunotherapy
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    nature.com/articles/s41598-022-06549-1
  105. Nov 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
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    sciencedirect.com/science/article/pii/S0896627321008667
  107. www.sciencedirect.com www.sciencedirect.com
    Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
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    sciencedirect.com/science/article/pii/S2211124721013851
  108. www.sciencedirect.com www.sciencedirect.com
    RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
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    sciencedirect.com/science/article/pii/S0092867421012320
  109. Oct 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
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    sciencedirect.com/science/article/pii/S2211124721012572
  111. Sep 2021
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8452306/
  113. Aug 2021
  114. www.nature.com www.nature.com
    The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing synaptic vesicle recycling pool in hippocampal neurons
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    nature.com/articles/s42003-021-02512-4
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8351540/
  116. www.sciencedirect.com www.sciencedirect.com
    A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
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    sciencedirect.com/science/article/pii/S2211124721008901
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6384025/
  118. www.sciencedirect.com www.sciencedirect.com
    Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability
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    sciencedirect.com/science/article/pii/S2211124721009049
  119. Jul 2021
  120. europepmc.org europepmc.org
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    europepmc.org/articles/PMC6302549/
  121. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718318424
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224479/
  123. May 2021
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    Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism
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