91 Matching Annotations
  1. Jan 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARγ and its target enhancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802833/
  3. www.science.org www.science.org
    Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators
    1
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    science.org/doi/10.1126/sciadv.adu8292
  4. Nov 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508145/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The lipid phosphatase INPP4B controls pancreatic cancer cell migration and invasion by regulating fibronectin exocytosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12547244/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intermediate Conductance Calcium‐Dependent Potassium Channel (KCa3.1) Interacting Proteins Using Turboid‐Based Proximity Labeling Technology: Insights Into Interactome and Related Signaling Pathways in Pancreatic Tumors
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12435150/
  8. www.sciencedirect.com www.sciencedirect.com
    FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI
    1
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    sciencedirect.com/science/article/pii/S2589004225017766
  9. Oct 2025
  10. www.nature.com www.nature.com
    Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
    1
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    nature.com/articles/s41467-025-64255-8
  11. www.sciencedirect.com www.sciencedirect.com
    Productive mRNA chromatin escape is promoted by PRMT5 activity
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    sciencedirect.com/science/article/pii/S1097276525007816
  12. Sep 2025
  13. www.sciencedirect.com www.sciencedirect.com
    FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI
    1
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    sciencedirect.com/science/article/pii/S2589004225017766
  14. link.springer.com link.springer.com
    Construction of Synthetic Probiotic Bacteria for In Situ Delivery of Anti-SARS-CoV-2 Nanobodies
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    link.springer.com/article/10.1007/s12602-025-10758-1
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting YAP/TAZ-TEAD signaling as a therapeutic approach in head and neck squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044704/
  16. Aug 2025
  17. www.sciencedirect.com www.sciencedirect.com
    A vascular-associated fibroblastic cell controls pancreatic islet immunity
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    sciencedirect.com/science/article/pii/S221112472500960X
  18. www.sciencedirect.com www.sciencedirect.com
    A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation
    1
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    sciencedirect.com/science/article/pii/S1097276525006513
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aging murine peritoneal macrophages undergo female-specific remodeling driven by hormone-dependent and independent mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262579/
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Butyrylcholinesterase (BChE) downregulation in taxane resistance: implications for prostate cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12266350/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Flow Cytometric Quantification of Mitochondrial Properties: A High-Throughput Approach for Single Organelle Analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12193137/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cypin regulates K63-linked polyubiquitination to shape synaptic content
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12248297/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167708/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reannotation of cancer mutations based on expressed RNA transcripts reveals functional non-coding mutations in melanoma
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12256795/
  26. Jun 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Resolved Panoramic in vivo CRISPR Screen via Perturb-DBiT
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12083649/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in the tumor microenvironment
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089342/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD37 regulates the self-renewal of leukemic stem cells via integrin-mediated signaling in acute myeloid leukemia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12143136/
  30. May 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PDF-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11990068/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12047821/
  33. 52.53.155.43 52.53.155.43
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    52.53.155.43/581690a87db32a6cd802c9bdccaa776024adf4bf/PDF-html.html
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VDAC2 loss elicits tumour destruction and inflammation for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12018455/
  35. Apr 2025
  36. www.sciencedirect.com www.sciencedirect.com
    Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias
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    sciencedirect.com/science/article/pii/S009286742500399X
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circadian clock features define novel subtypes among breast cancer cells and shape drug sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11965565/
  38. Mar 2025
  39. www.sciencedirect.com www.sciencedirect.com
    SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
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    sciencedirect.com/science/article/pii/S2211124725002050
  40. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
  42. www.sciencedirect.com www.sciencedirect.com
    Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors
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    sciencedirect.com/science/article/pii/S2666166725000917
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastatic organotropism in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11483079/
  44. Feb 2025
  45. www.sciencedirect.com www.sciencedirect.com
    A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation
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    sciencedirect.com/science/article/pii/S1097276525000036
  46. Jan 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
  48. www.sciencedirect.com www.sciencedirect.com
    Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calcium
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    sciencedirect.com/science/article/pii/S0021925825000304
  49. 52.53.155.43 52.53.155.43
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    52.53.155.43/536d4d4f3cdb6d7a39ee26c6732b96f318bba10f/PDF-html.html
  50. Dec 2024
  51. www.sciencedirect.com www.sciencedirect.com
    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
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    sciencedirect.com/science/article/pii/S2666379124006396
  52. Nov 2024
  53. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  54. www.sciencedirect.com www.sciencedirect.com
    Degradome analysis to identify direct protein substrates of small-molecule degraders
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    sciencedirect.com/science/article/pii/S2451945624004422
  55. Sep 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11256575/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394141/
  58. Aug 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PUS7‐dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341916/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
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    ncbi.nlm.nih.gov/pmc/articles/PMC11339390/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321652/
  62. Jun 2024
  63. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
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    cell.com/iscience/abstract/S2589-0042(24)01356-7
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148551/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
  66. May 2024
  67. 52.53.155.43 52.53.155.43
    mct-23-0285-html.html
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    52.53.155.43/c4dad1b9844bc76f61b814848871e558944174e3/mct-23-0285-html.html
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11065178/
  69. www.sciencedirect.com www.sciencedirect.com
    Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
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    sciencedirect.com/science/article/pii/S221112472400514X
  70. Apr 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular density-accelerated binding-site maturation underlies CENP-T-dependent kinetochore assembly
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10925139/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10958866/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ether lipids influence cancer cell fate by modulating iron uptake
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983928/
  75. www.sciencedirect.com www.sciencedirect.com
    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
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    sciencedirect.com/science/article/pii/S2666979X24000934
  76. Mar 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct ontogenetic lineages dictate cDC2 heterogeneity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10907303/
  78. Feb 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11192630/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of LATS kinases reduces tumorigenicity and increases the sensitivity of human chronic myelogenous leukemia cells to imatinib
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    ncbi.nlm.nih.gov/pmc/articles/PMC10874434/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12
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    ncbi.nlm.nih.gov/pmc/articles/PMC10853541/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10861560/
  83. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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    sciencedirect.com/science/article/pii/S240547122400022X
  84. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
  86. Jan 2024
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets
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    ncbi.nlm.nih.gov/pmc/articles/PMC10693625/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation, and proteomic profiles in Burkitt lymphoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000110/
  89. Aug 2023
  90. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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    sciencedirect.com/science/article/pii/S2589004223015262
  91. May 2023
  92. www.biorxiv.org www.biorxiv.org
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation and proteomic profiles in Burkitt lymphoma
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    biorxiv.org/content/10.1101/2023.05.19.538556v1
  93. Apr 2023
  94. elifesciences.org elifesciences.org
    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
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    elifesciences.org/articles/81569
  95. Nov 2022
  96. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
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    sciencedirect.com/science/article/pii/S2211124722015947
  97. Oct 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  99. Sep 2022
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1111/cas.15558
  101. Aug 2022
  102. www.sciencedirect.com www.sciencedirect.com
    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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    sciencedirect.com/science/article/pii/S1535610822003245
  103. Jun 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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    sciencedirect.com/science/article/pii/S1097276522004920
  105. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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    link.springer.com/article/10.1007/s10120-022-01307-8
  106. Mar 2022
  107. www.nature.com www.nature.com
    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
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    nature.com/articles/s41375-022-01536-x
  108. www.sciencedirect.com www.sciencedirect.com
    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
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    sciencedirect.com/science/article/pii/S107476132200084X
  109. Jan 2022
  110. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
    2
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    sciencedirect.com/science/article/pii/S1074761321005434
  111. Oct 2021
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tumor cell intrinsic TLR4 signaling promotes melanoma progression and metastatic dissemination
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33804
  113. Aug 2021
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
  115. Jul 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
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    ncbi.nlm.nih.gov/pmc/articles/PMC7925120/
  117. May 2021
  118. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  119. Feb 2021
  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The aryl hydrocarbon receptor promotes inflammation‐induced dedifferentiation and systemic metastatic spread of melanoma cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33252
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7882221/
  122. Nov 2020
  123. www.nature.com www.nature.com
    Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein
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    nature.com/articles/s41598-020-76135-w
  124. Sep 2020
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  126. www.sciencedirect.com www.sciencedirect.com
    Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25
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    sciencedirect.com/science/article/pii/S2211124720309074
  127. doi.org doi.org
    https://doi.org/10.1101/2020.06.08.140236
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    doi.org/10.1101/2020.06.08.140236
  128. Jan 2020
  129. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1934590918305927