84 Matching Annotations
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    Productive mRNA chromatin escape is promoted by PRMT5 activity
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    sciencedirect.com/science/article/pii/S1097276525007816
  3. Sep 2025
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    FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI
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    sciencedirect.com/science/article/pii/S2589004225017766
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    Construction of Synthetic Probiotic Bacteria for In Situ Delivery of Anti-SARS-CoV-2 Nanobodies
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    link.springer.com/article/10.1007/s12602-025-10758-1
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    Targeting YAP/TAZ-TEAD signaling as a therapeutic approach in head and neck squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044704/
  7. Aug 2025
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    A vascular-associated fibroblastic cell controls pancreatic islet immunity
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    sciencedirect.com/science/article/pii/S221112472500960X
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    A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation
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    sciencedirect.com/science/article/pii/S1097276525006513
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    Aging murine peritoneal macrophages undergo female-specific remodeling driven by hormone-dependent and independent mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262579/
  11. Jul 2025
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    Butyrylcholinesterase (BChE) downregulation in taxane resistance: implications for prostate cancer
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    Flow Cytometric Quantification of Mitochondrial Properties: A High-Throughput Approach for Single Organelle Analysis
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    Cypin regulates K63-linked polyubiquitination to shape synaptic content
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    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167708/
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    Reannotation of cancer mutations based on expressed RNA transcripts reveals functional non-coding mutations in melanoma
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  17. Jun 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Resolved Panoramic in vivo CRISPR Screen via Perturb-DBiT
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    Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in the tumor microenvironment
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    CD37 regulates the self-renewal of leukemic stem cells via integrin-mediated signaling in acute myeloid leukemia
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  21. May 2025
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    Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter
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    VDAC2 loss elicits tumour destruction and inflammation for cancer therapy
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  26. Apr 2025
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    Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias
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    Circadian clock features define novel subtypes among breast cancer cells and shape drug sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11965565/
  29. Mar 2025
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    SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
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    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
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    Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia
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    Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors
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    Metastatic organotropism in small cell lung cancer
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  35. Feb 2025
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    A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation
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  37. Jan 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition
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    Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calcium
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  41. Dec 2024
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    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
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  43. Nov 2024
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    Degradome analysis to identify direct protein substrates of small-molecule degraders
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  46. Sep 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells
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    PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells
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  49. Aug 2024
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    PUS7‐dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression
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    Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
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    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
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  53. Jun 2024
  54. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
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    cell.com/iscience/abstract/S2589-0042(24)01356-7
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    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
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  57. May 2024
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    NFATC2IP is a mediator of SUMO-dependent genome integrity
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    Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
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  61. Apr 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
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    Molecular density-accelerated binding-site maturation underlies CENP-T-dependent kinetochore assembly
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    Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development
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    Ether lipids influence cancer cell fate by modulating iron uptake
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    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
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  67. Mar 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct ontogenetic lineages dictate cDC2 heterogeneity
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  69. Feb 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice
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    Inhibition of LATS kinases reduces tumorigenicity and increases the sensitivity of human chronic myelogenous leukemia cells to imatinib
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    The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12
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    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
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    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
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  77. Jan 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets
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    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation, and proteomic profiles in Burkitt lymphoma
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  80. Aug 2023
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    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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  82. May 2023
  83. www.biorxiv.org www.biorxiv.org
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation and proteomic profiles in Burkitt lymphoma
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    biorxiv.org/content/10.1101/2023.05.19.538556v1
  84. Apr 2023
  85. elifesciences.org elifesciences.org
    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
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    elifesciences.org/articles/81569
  86. Nov 2022
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    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
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    sciencedirect.com/science/article/pii/S2211124722015947
  88. Oct 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  90. Sep 2022
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1111/cas.15558
  92. Aug 2022
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    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
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  94. Jun 2022
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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    link.springer.com/article/10.1007/s10120-022-01307-8
  97. Mar 2022
  98. www.nature.com www.nature.com
    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
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    nature.com/articles/s41375-022-01536-x
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    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
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    sciencedirect.com/science/article/pii/S107476132200084X
  100. Jan 2022
  101. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
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    sciencedirect.com/science/article/pii/S1074761321005434
  102. Oct 2021
  103. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tumor cell intrinsic TLR4 signaling promotes melanoma progression and metastatic dissemination
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33804
  104. Aug 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  106. Jul 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
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    ncbi.nlm.nih.gov/pmc/articles/PMC7925120/
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  110. Feb 2021
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The aryl hydrocarbon receptor promotes inflammation‐induced dedifferentiation and systemic metastatic spread of melanoma cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33252
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7882221/
  113. Nov 2020
  114. www.nature.com www.nature.com
    Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein
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    nature.com/articles/s41598-020-76135-w
  115. Sep 2020
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
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    Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25
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    sciencedirect.com/science/article/pii/S2211124720309074
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    https://doi.org/10.1101/2020.06.08.140236
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  119. Jan 2020
  120. www.sciencedirect.com www.sciencedirect.com
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