Hypothesis

37 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

1
1. scibot 24 Nov 2025
  
  in Public
  
  Addgene_154754
  
  DOI: 10.1038/s42003-025-08819-w
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12501226/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An RGD motif on SARS-CoV-2 Spike induces TGF-β signaling and downregulates interferon

1
1. scibot 23 Nov 2025
  
  in Public
  
  154754/
  
  DOI: 10.1128/jvi.00435-25
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12456147/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cross-reactivity IgG, viral load, severity and vaccination outcome as an approach for understanding humoral immune response against SARS-CoV-2

1
1. scibot 21 Nov 2025
  
  in Public
  
  154754
  
  DOI: 10.1186/s12879-025-12038-3
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12625219/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium

1
1. scibot 21 Nov 2025
  
  in Public
  
  154754
  
  DOI: 10.1172/JCI184514
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12618076/
Sep 2025
journals.asm.org journals.asm.org

An RGD motif on SARS-CoV-2 Spike induces TGF-β signaling and downregulates interferon

1
1. scibot 09 Sep 2025
  
  in Public
  
  Addgene plasmid, https://www.addgene.org/154754/
  
  DOI: 10.1128/jvi.00435-25
  
  Resource: RRID:Addgene_154754
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

journals.asm.org/doi/10.1128/jvi.00435-25
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cryo-EM reveals conformational variability in the SARS-CoV-2 spike protein RBD induced by two broadly neutralizing monoclonal antibodies

1
1. scibot 19 May 2025
  
  in Public
  
  plasmid_154754
  
  DOI: 10.1039/d5ra00373c
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12053377/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Skin patch delivery of a SARS-CoV-2 spike DNA vaccine produces broad neutralising antibody responses

1
1. scibot 11 Mar 2025
  
  in Public
  
  154754
  
  DOI: 10.1016/j.heliyon.2025.e42533
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11872540/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation

1
1. scibot 28 Dec 2024
  
  in Public
  
  plasmid_154754
  
  DOI: 10.1128/jvi.01223-24
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11650997/
Sep 2024
www.science.org www.science.org

The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation

1
1. scibot 26 Sep 2024
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1126/scisignal.adn3785
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

science.org/doi/10.1126/scisignal.adn3785
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients

1
1. scibot 25 Sep 2024
  
  in Public
  
  154754
  
  DOI: 10.26508/lsa.202402774
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11408605/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses

1
1. scibot 21 Aug 2024
  
  in Public
  
  154754
  
  DOI: 10.1038/s41565-024-01655-9
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11329374/
www.sciencedirect.com www.sciencedirect.com

Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

1
1. scibot 18 Aug 2024
  
  in Public
  
  Plasmid_154754
  
  DOI: 10.1016/j.xcrm.2024.101668
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124003823
May 2024
bmcoralhealth.biomedcentral.com bmcoralhealth.biomedcentral.com

Precise control of digital dental unit to reduce aerosol and splatter production: new challenges for future epidemics

1
1. scibot 22 May 2024
  
  in Public
  
  rRID: Addgene_154754
  
  DOI: 10.1186/s12903-024-03980-w
  
  Resource: RRID:Addgene_154754
  
  Curator: @anisehay
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-024-03980-w
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage

1
1. scibot 22 Mar 2024
  
  in Public
  
  Plasmid_154754
  
  DOI: 10.7554/eLife.86764
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10954308/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models

1
1. scibot 01 Feb 2024
  
  in Public
  
  154754
  
  DOI: 10.1038/s41467-024-44830-1
  
  Resource: RRID:Addgene_154754
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10796936/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity

1
1. scibot 14 Oct 2023
  
  in Public
  
  plasmid_154754
  
  DOI: 10.1016/j.celrep.2023.113194
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723012068
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1016/j.immuni.2023.09.003
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761323004089
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting spike glycans to inhibit SARS-CoV2 viral entry

1
1. scibot 28 Sep 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1073/pnas.2301518120
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10515186/
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adaptation of the binding domain of Lactobacillus acidophilus S-layer protein as a molecular tag for affinity chromatography development

2
1. scibot 30 Jun 2023
  
  in Public
  
  Addgene_154754
  
  DOI: 10.3389/fmicb.2023.1210898
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
2. scibot 30 Jun 2023
  
  in Public
  
  RRID:addgene_154754
  
  DOI: 10.3389/fmicb.2023.1210898
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10293925/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity

2
1. scibot 24 Jun 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1126/sciadv.adg2248
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
2. scibot 10 Jun 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1126/sciadv.adg2248
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10246911/
May 2023
www.sciencedirect.com www.sciencedirect.com

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

1
1. scibot 12 May 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1016/j.str.2023.04.010
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0969212623001338
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs

1
1. scibot 15 Feb 2023
  
  in Public
  
  Addgene_154754
  
  DOI: 10.1371/journal.pbio.3001967
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
pubs.acs.org pubs.acs.org

SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck

1
1. scibot 09 Feb 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1021/acschemneuro.2c00610
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

pubs.acs.org/doi/full/10.1021/acschemneuro.2c00610
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry

1
1. scibot 11 Jan 2023
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1101/2022.12.22.521642
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9810211/
Nov 2022
www.nature.com www.nature.com

Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice

1
1. scibot 16 Nov 2022
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1038/s41467-022-34297-3
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

nature.com/articles/s41467-022-34297-3
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein

1
1. scibot 23 Aug 2022
  
  in Public
  
  Addgene_154754
  
  DOI: 10.1016/j.chom.2022.07.016
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312822003626
www.nature.com www.nature.com

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

1
1. scibot 23 Aug 2022
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1038/s41467-022-32262-8
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

nature.com/articles/s41467-022-32262-8
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

1
1. scibot 27 Jul 2022
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1016/j.vaccine.2022.07.013
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9291373/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Superimmunity by pan-sarbecovirus nanobodies

1
1. scibot 24 Jun 2022
  
  in Public
  
  Addgene154754
  
  DOI: 10.1016/j.celrep.2022.111004
  
  Resource: RRID:Addgene_154754
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722007938
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants

1
1. scibot 04 Mar 2022
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1038/s41467-022-28324-6
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8826856/
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding

1
1. scibot 17 Dec 2021
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1016/j.celrep.2021.110156
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8642162/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Beta RBD Boost Broadens Antibody-Mediated Protection Against SARS-CoV-2 Variants in Animal Models

1
1. scibot 18 Nov 2021
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1016/j.xcrm.2021.100450
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379121003189
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine

1
1. scibot 16 Nov 2021
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1126/sciadv.abj8065
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8555896/
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2

1
1. scibot 28 May 2021
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.3390/vaccines9050498
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8151071/
journals.plos.org journals.plos.org

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies

1
1. scibot 04 May 2021
  
  in Public
  
  RRID:Addgene_154754
  
  DOI: 10.1371/journal.pbio.3001237
  
  Resource: RRID:Addgene_154754
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_154754
  
  What is this?
  
  RRID:Addgene_154754
Visit annotations in context

Tags

RRID:Addgene_154754

Annotators

scibot

URL

journals.plos.org/plosbiology/article