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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precise correction of G6PD Viangchan mutation in iPSCs by prime editing strategy

1
1. scibot 21 Aug 2025
  
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  Addgene_174038
  
  DOI: 10.1038/s41598-025-15463-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12361394/
Jul 2025
www.cell.com www.cell.com

In vivo prime editing rescues alternating hemiplegia of childhood in mice

1
1. scibot 25 Jul 2025
  
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  Addgene_174038
  
  DOI: 10.1016/j.cell.2025.06.038
  
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cell.com/cell/fulltext/S0092-8674(25)00740-8
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precise Correction of the Pde6b-L659P Mutation Causing Retinal Degeneration with Minimum Bystander Editing by Advanced Genome Editing Tools

1
1. scibot 20 Jul 2025
  
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  174038
  
  DOI: 10.34133/research.0770
  
  Resource: RRID:Addgene_174038
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12220932/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Effects of heterozygous SMG1 mutations on nonsense-mediated mRNA decay in human pluripotent stem cell model

1
1. scibot 20 Jul 2025
  
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  174038
  
  DOI: 10.1016/j.mocell.2025.100225
  
  Resource: RRID:Addgene_174038
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12173119/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In Vitro Correction of Point Mutations in the DYSF Gene Using Prime Editing

1
1. scibot 20 Jul 2025
  
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  Addgene_174038
  
  DOI: 10.3390/ijms26125647
  
  Resource: RRID:Addgene_174038
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12193300/
Jun 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 28 Jun 2025
  
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  Addgene, #174038
  
  DOI: 10.1002/1873-3468.70097
  
  Resource: RRID:Addgene_174038
  
  Curator: @dhovakimyan1
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70097
May 2025
www.sciencedirect.com www.sciencedirect.com

Protocol to perform multiplexed assays of variant effect using curated loci prime editing

1
1. scibot 29 May 2025
  
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  RRID:Addgene174038
  
  DOI: 10.1016/j.xpro.2025.103851
  
  Resource: RRID:Addgene_174038
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2666166725002576
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Universal Prime Editing Therapeutic Strategy for RyR1-Related Myopathies: A Protective Mutation Rescues Leaky RyR1 Channel

2
1. scibot 21 May 2025
  
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  plasmid_174038
  
  DOI: 10.3390/ijms26072835
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
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2. scibot 17 May 2025
  
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  174038
  
  DOI: 10.3390/ijms26072835
  
  Resource: RRID:Addgene_174038
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11988564/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Prime Editor Gene Therapy and TREX1 Mosaicism in Retinal Vasculopathy with Cerebral Leukoencephalopathy

1
1. scibot 27 Dec 2024
  
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  174038
  
  DOI: 10.1007/s10875-024-01846-y
  
  Resource: RRID:Addgene_174038
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11645301/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools

1
1. scibot 22 Aug 2024
  
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  plasmid_174038
  
  DOI: 10.1016/j.xpro.2024.103189
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11298932/
www.sciencedirect.com www.sciencedirect.com

The FXR1 network acts as a signaling scaffold for actomyosin remodeling

1
1. scibot 19 Aug 2024
  
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  Addgene_174038
  
  DOI: 10.1016/j.cell.2024.07.015
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S009286742400775X
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multimodal framework to resolve variants of uncertain significance in TSC2

1
1. scibot 27 Jun 2024
  
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  plasmid_174038
  
  DOI: 10.1101/2024.06.07.597916
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11185720/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor

1
1. scibot 15 Jun 2024
  
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  plasmid_174038
  
  DOI: 10.1093/nar/gkae310
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11162781/
May 2024
www.sciencedirect.com www.sciencedirect.com

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

1
1. scibot 02 May 2024
  
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  Addgene: 174038
  
  DOI: 10.1016/j.xcrm.2024.101544
  
  Resource: RRID:Addgene_174038
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_174038
  
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sciencedirect.com/science/article/pii/S2666379124002349
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes

1
1. scibot 23 Apr 2024
  
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  Plasmid_174038
  
  DOI: 10.1038/s41467-024-46795-7
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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ncbi.nlm.nih.gov/pmc/articles/PMC11026479/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enhancing prime editor activity by directed protein evolution in yeast

1
1. scibot 17 Mar 2024
  
  in Public
  
  Addgene #174038
  
  DOI: 10.1038/s41467-024-46107-z
  
  Resource: RRID:Addgene_174038
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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ncbi.nlm.nih.gov/pmc/articles/PMC10920827/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Benzomorphan and non-benzomorphan agonists differentially alter sigma-1 receptor quaternary structure, as does types of cellular stress

1
1. scibot 08 Feb 2024
  
  in Public
  
  plasmid_174038
  
  DOI: 10.1007/s00018-023-05023-z
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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ncbi.nlm.nih.gov/pmc/articles/PMC10774196/
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms

1
1. scibot 11 Jan 2024
  
  in Public
  
  plasmid_174038
  
  DOI: 10.1016/j.scr.2024.103304
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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sciencedirect.com/science/article/pii/S1873506124000023
www.sciencedirect.com www.sciencedirect.com

Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo

1
1. scibot 11 Jan 2024
  
  in Public
  
  Addgene_174038
  
  DOI: 10.1016/j.stem.2023.12.003
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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sciencedirect.com/science/article/pii/S1934590923004332
Dec 2023
www.biorxiv.org www.biorxiv.org

Creation of de novo cryptic splicing for ALS/FTD precision medicine

1
1. scibot 02 Dec 2023
  
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  RRID:Addgene_174038
  
  DOI: 10.1101/2023.11.15.565967
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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biorxiv.org/content/10.1101/2023.11.15.565967v1
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need

1
1. scibot 04 Nov 2023
  
  in Public
  
  RRID:Addgene_174038
  
  DOI: 10.1016/j.ajhg.2023.10.005
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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sciencedirect.com/science/article/pii/S0002929723003580
Sep 2023
www.nature.com www.nature.com

CRISPR prime editing for unconstrained correction of oncogenic KRAS variants

1
1. scibot 20 Sep 2023
  
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  174038
  
  DOI: 10.1038/s42003-023-05052-1
  
  Resource: RRID:Addgene_174038
  
  Curator: @bandrow
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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nature.com/articles/s42003-023-05052-1
Jun 2023
www.nature.com www.nature.com

Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing

1
1. scibot 13 Jun 2023
  
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  RRID:Addgene_174038
  
  DOI: 10.1038/s41467-023-39246-2
  
  Resource: RRID:Addgene_174038
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_174038
  
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  RRID:Addgene_174038
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nature.com/articles/s41467-023-39246-2