99 Matching Annotations
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    MeCP2 regulates telencephalic development in human cerebral organoids
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    sciencedirect.com:5037/science/article/pii/S2211124725014421
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blocking nuclear receptor Nr4a3 unlocks the senescence barrier to promote direct cardiac reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC12617505/
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    ANTXR1 blockade enhances cardiac function in preclinical models of heart failure
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    Targeting FADS1-mediated lipid metabolism and signaling: a novel therapeutic strategy for precision oncology in colorectal and esophageal cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533223/
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    Epigenetic regulation of TIPE3 in nasopharyngeal carcinoma and its impact on the hedgehog signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615883/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Herpes simplex virus diverts CIN85 endosomal cargo for exocytosis to evade antiviral responses: a novel role for the viral immediate-early protein ICP0
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    pmc.ncbi.nlm.nih.gov/articles/PMC12607867/
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    Long noncoding RNA LncBAR enhances BRG1 protein to promote cardiomyocyte cell cycle progression and cardiac repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC12623768/
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    A cytoplasmic motif in HLA-E that drives clathrin-mediated endocytosis and VCP-associated postendocytic trafficking
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582296/
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    Targeting of SKP2 to combat drug resistance in multiple myeloma
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  12. Oct 2025
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    PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy
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    PRDM16 regulates smooth muscle cell identity and atherosclerotic plaque composition
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    nature.com/articles/s44161-025-00737-8
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    Amyloidogenic propensity of self-assembling peptides and their adjuvant potential for use as DNA vaccines
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  16. Sep 2025
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    Nucleosome stability safeguards cell identity, stress resilience and healthy aging
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    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors
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    ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy
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  20. Aug 2025
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    Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems
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    Functional Differences Between SIRPα Splice Isoforms
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  23. Jul 2025
  24. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
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    Loss of Eml1 alters microtubule-associated protein networks in mouse brain heterotopia
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    CCNY-mediated phosphorylation and TET2-BACH1-driven DNA demethylation activate PRC1 to augment NSCLC progression
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    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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  28. Jun 2025
  29. www.nature.com www.nature.com
    Nerve-to-cancer transfer of mitochondria during cancer metastasis
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    De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation
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    Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control
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  32. May 2025
  33. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    Establishment of bovine extraembryonic endoderm stem cells enables efficient blastoid formation
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    m6A-Modified GATA2 Enhances Odontogenic Differentiation in Stem Cells from the Apical Papilla
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose
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    A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct
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    A Hydrogel-Based Multiplex Coculture Platform for Retinal Component Cells
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  40. Apr 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth
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  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Promyelocytic Leukemia Protein (PML) Regulates Stem Cell Pluripotency Through Novel Sumoylation Targets
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  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vitro and in vivo neutralization of Dengue virus by a single domain antibody
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    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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  45. Mar 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glioblastoma progression is hindered by melatonin-primed mesenchymal stromal cells through dynamic intracellular and extracellular reorganizations
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    Haplotype rather than single causal variants effects contribute to regulatory gene expression associations in human myeloid cells
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  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nematode serine protease inhibitor SPI-I8 negatively regulates host NF-κB signalling by hijacking MKRN1-mediated polyubiquitination of RACK1
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    Characterization of spike S1/S2 processing and entry pathways of lentiviral pseudoviruses bearing seasonal human coronaviruses NL63, 229E, and HKU1 spikes
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  50. Feb 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRDM16 controls smooth muscle cell fate in atherosclerosis
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  53. Jan 2025
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional regulation of adipocyte lipolysis by IRF2BP2
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  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831618/
  56. Dec 2024
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of Liver-Targeting αVβ5+ Exosomes as Anti-TGF-β Nanocarriers for the Treatment of the Pre-Metastatic Niche
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    Fibrosis‐Encapsulated Tumoroid, A Solid Cancer Assembloid Model for Cancer Research and Drug Screening
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  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptor protein 3BP2 regulates gene expression in addition to the ubiquitination and proteolytic activity of MALT1 in dectin-1–stimulated cells
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  60. Oct 2024
  61. www.mdpi.com www.mdpi.com
    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
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  62. Sep 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    New Insights into the Exosome-Induced Migration of Uveal Melanoma Cells and the Pre-Metastatic Niche Formation in the Liver
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    The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode
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  66. Aug 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric nanobodies to study the interactions between SOS1 and RAS
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD
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    Transcriptional regulation of adipocyte lipolysis by IRF2BP2
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    biorxiv.org/content/10.1101/2024.07.31.605689v1
  71. Jul 2024
  72. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11187196/
  74. Jun 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
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    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
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    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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  78. May 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
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    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042251/
  81. Apr 2024
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Heat-Induced Stress Granules in the Blood–Testis Barrier of Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11011666/
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    Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025283/
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    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
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    sciencedirect.com/science/article/pii/S1074761324001419
  86. Mar 2024
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Plexiform Neurofibroma Cells at Doses That Do Not Affect Patient-Matched Schwann Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10975375/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A FACS-based novel isolation technique identifies heterogeneous CTCs in oral squamous cell carcinoma
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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  90. Jan 2024
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10806012/
  92. Dec 2023
  93. www.mdpi.com www.mdpi.com
    A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
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    mdpi.com/2072-6694/15/24/5773
  94. Nov 2023
  95. www.biorxiv.org www.biorxiv.org
    Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
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    biorxiv.org/content/10.1101/2023.10.20.563266v1
  96. Sep 2023
  97. dx.doi.org dx.doi.org
    Loss of CDKN2A Cooperates with WWTR1(TAZ)–CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma
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    dx.doi.org/10.1158/1078-0432.CCR-22-2497
  98. www.nature.com www.nature.com
    β2-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery
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    nature.com/articles/s41419-023-06129-9
  99. Aug 2023
  100. www.sciencedirect.com www.sciencedirect.com
    Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation
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    sciencedirect.com/science/article/pii/S0021925823021336
  101. May 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
  103. Apr 2023
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9971359/
  105. Jan 2023
  106. www.science.org www.science.org
    Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases
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    science.org/doi/10.1126/sciimmunol.abp9765
  107. Aug 2022
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    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    sciencedirect.com/science/article/pii/S2211124722011081
  109. Jun 2022
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    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
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    sciencedirect.com/science/article/pii/S2589004222008215
  111. Apr 2022
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  113. Mar 2022
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant induction of a mesenchymal/stem-cell program engages senescence in normal mammary epithelial cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC8867383/
  115. Nov 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera
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    sciencedirect.com/science/article/pii/S2589004221013109
  117. Sep 2021
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    GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility
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  119. Aug 2021
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    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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  121. Jul 2021
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    Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain
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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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  124. May 2021
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    3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
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  126. Mar 2021
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    ER-directed TREX1 limits cGAS activation at micronuclei
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  128. Feb 2021
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    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
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    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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  132. Dec 2020
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    An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2
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  134. Sep 2020
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    An Optimized Protocol for Human Direct Cardiac Reprogramming
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    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
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  138. Jan 2020
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    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
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    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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