42 Matching Annotations
  1. Jul 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1
    1
    1. scibot 01 Jul 2024
      Addgene_17448

      DOI: 10.1038/s41598-024-64767-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11187196/
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
    1
    1. scibot 07 Jun 2024
      17448

      DOI: 10.1038/s41467-024-48695-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11102494/
  5. www.sciencedirect.com www.sciencedirect.com
    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
    1
    1. scibot 07 Jun 2024
      Plasmid_17448

      DOI: 10.1016/j.cell.2024.05.001

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    sciencedirect.com/science/article/pii/S0092867424004914
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
    1
    1. scibot 03 Jun 2024
      17448

      DOI: 10.1126/sciadv.adn7732

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    ncbi.nlm.nih.gov/pmc/articles/PMC11135424/
  7. May 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
    1
    1. scibot 12 May 2024
      Plasmid_17448

      DOI: 10.3390/ijms25094953

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    ncbi.nlm.nih.gov/pmc/articles/PMC11084921/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors
    1
    1. scibot 05 May 2024
      17448

      DOI: 10.1101/2024.04.15.589533

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042251/
  10. Apr 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability
    1
    1. scibot 30 Apr 2024
      plasmid_17448

      DOI: 10.1101/2024.04.11.589139

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042198/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Heat-Induced Stress Granules in the Blood–Testis Barrier of Mice
    1
    1. scibot 23 Apr 2024
      17448

      DOI: 10.3390/ijms25073637

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011666/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia
    1
    1. scibot 23 Apr 2024
      17,448

      DOI: 10.1186/s12951-024-02473-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025283/
  14. www.sciencedirect.com www.sciencedirect.com
    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
    1
    1. scibot 18 Apr 2024
      RRID:Addgene_17448

      DOI: 10.1016/j.immuni.2024.03.020

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    sciencedirect.com/science/article/pii/S1074761324001419
  15. Mar 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Plexiform Neurofibroma Cells at Doses That Do Not Affect Patient-Matched Schwann Cells
    1
    1. scibot 31 Mar 2024
      17448

      DOI: 10.3390/pharmaceutics16030371

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    ncbi.nlm.nih.gov/pmc/articles/PMC10975375/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A FACS-based novel isolation technique identifies heterogeneous CTCs in oral squamous cell carcinoma
    1
    1. scibot 16 Mar 2024
      17448

      DOI: 10.3389/fonc.2024.1269211

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    ncbi.nlm.nih.gov/pmc/articles/PMC10925612/
  18. www.sciencedirect.com www.sciencedirect.com
    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
    1
    1. scibot 14 Mar 2024
      AddgeneCat#17448

      DOI: 10.1016/j.xpro.2024.102943

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    sciencedirect.com/science/article/pii/S2666166724001084
  19. Jan 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids
    1
    1. scibot 28 Jan 2024
      17448

      DOI: 10.3389/fcell.2023.1268226

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    ncbi.nlm.nih.gov/pmc/articles/PMC10806012/
  21. Dec 2023
  22. www.mdpi.com www.mdpi.com
    A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
    1
    1. scibot 14 Dec 2023
      RRID:Addgene_17448

      DOI: 10.3390/cancers15245773

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    mdpi.com/2072-6694/15/24/5773
  23. Nov 2023
  24. www.biorxiv.org www.biorxiv.org
    Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
    1
    1. scibot 03 Nov 2023
      Addgene_17448

      DOI: 10.1101/2023.10.20.563266

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    biorxiv.org/content/10.1101/2023.10.20.563266v1
  25. Sep 2023
  26. dx.doi.org dx.doi.org
    Loss of CDKN2A Cooperates with WWTR1(TAZ)–CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma
    1
    1. scibot 20 Sep 2023
      plasmid_17448

      DOI: 10.1158/1078-0432.CCR-22-2497

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    dx.doi.org/10.1158/1078-0432.CCR-22-2497
  27. www.nature.com www.nature.com
    β2-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery
    1
    1. scibot 20 Sep 2023
      RRID:Addgene_17448

      DOI: 10.1038/s41419-023-06129-9

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    nature.com/articles/s41419-023-06129-9
  28. Aug 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation
    1
    1. scibot 03 Aug 2023
      RRID:Addgene_17448

      DOI: 10.1016/j.jbc.2023.105105

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    sciencedirect.com/science/article/pii/S0021925823021336
  30. May 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus
    1
    1. scibot 06 May 2023
      plasmid_17448

      DOI: 10.3389/fimmu.2023.1181014

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    ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
  32. Apr 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis
    1
    1. scibot 04 Apr 2023
      RRID:Addgene_17448

      DOI: 10.1158/0008-5472.CAN-22-0283

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    ncbi.nlm.nih.gov/pmc/articles/PMC9971359/
  34. Jan 2023
  35. www.science.org www.science.org
    Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases
    1
    1. scibot 27 Jan 2023
      RRID: Addgene 17448

      DOI: 10.1126/sciimmunol.abp9765

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      Curator: @sofiakhan13

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    science.org/doi/10.1126/sciimmunol.abp9765
  36. Aug 2022
  37. www.sciencedirect.com www.sciencedirect.com
    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
    1
    1. scibot 31 Aug 2022
      plasmid_17448

      DOI: 10.1016/j.celrep.2022.111288

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    sciencedirect.com/science/article/pii/S2211124722011081
  38. Jun 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
    1
    1. scibot 24 Jun 2022
      Addgene#17448

      DOI: 10.1016/j.isci.2022.104549

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    sciencedirect.com/science/article/pii/S2589004222008215
  40. Apr 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
    1
    1. scibot 01 Apr 2022
      Addgene17448

      DOI: 10.1016/j.isci.2022.104058

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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  42. Mar 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant induction of a mesenchymal/stem-cell program engages senescence in normal mammary epithelial cells.
    1
    1. scibot 04 Mar 2022
      plasmid_17448

      DOI: 10.1158/1541-7786.MCR-19-1181

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    ncbi.nlm.nih.gov/pmc/articles/PMC8867383/
  44. Nov 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera
    1
    1. scibot 09 Nov 2021
      plasmid_17448

      DOI: 10.1016/j.isci.2021.103341

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    sciencedirect.com/science/article/pii/S2589004221013109
  46. Sep 2021
  47. www.sciencedirect.com www.sciencedirect.com
    GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility
    1
    1. scibot 02 Sep 2021
      Addgene_17448

      DOI: 10.1016/j.celrep.2021.109621

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    sciencedirect.com/science/article/pii/S2211124721010597
  48. Aug 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
    1
    1. scibot 11 Aug 2021
      Addgene Cat. #17448

      DOI: 10.1016/j.celrep.2021.109512

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    sciencedirect.com/science/article/pii/S2211124721009426
  50. Jul 2021
  51. elifesciences.org elifesciences.org
    Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain
    1
    1. scibot 29 Jul 2021
      pLenti CMV GFP Puro

      DOI: 10.7554/eLife.46500

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    elifesciences.org/articles/46500
  52. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 27 Jul 2021
      RRID_Addgene_17448

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  53. May 2021
  54. www.sciencedirect.com www.sciencedirect.com
    3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
    1
    1. scibot 06 May 2021
      Addgene_17448

      DOI: 10.1016/j.devcel.2021.02.017

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    sciencedirect.com/science/article/pii/S153458072100157X
  55. Mar 2021
  56. www.sciencedirect.com www.sciencedirect.com
    ER-directed TREX1 limits cGAS activation at micronuclei
    1
    1. scibot 01 Mar 2021
      Addgene_17448

      DOI: 10.1016/j.molcel.2020.12.037

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    sciencedirect.com/science/article/pii/S1097276520309588
  57. Feb 2021
  58. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_17448

      DOI: 10.1016/j.molcel.2021.01.030

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    sciencedirect.com/science/article/pii/S1097276521000502
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_17448

      DOI: 10.3389/fncel.2020.00151

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    ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
  60. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 24 Feb 2021
      RRID:_Addgene_17448

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  61. Dec 2020
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2
    1
    1. scibot 17 Dec 2020
      plasmid_17448

      DOI: 10.1016/j.celrep.2020.108528

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    ncbi.nlm.nih.gov/pmc/articles/PMC7705358/
  63. Sep 2020
  64. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 12 Sep 2020
      RRID:Addgene_17448

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  65. www.sciencedirect.com www.sciencedirect.com
    An Optimized Protocol for Human Direct Cardiac Reprogramming
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_17448

      DOI: 10.1016/j.xpro.2019.100010

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    sciencedirect.com/science/article/pii/S2666166719300103
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
    1
    1. scibot 03 Sep 2020
      RRID: Addgene_17448

      DOI: 10.3389/fncel.2020.00151

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    ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
  67. Jan 2020
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
    1
    1. scibot 13 Jan 2020
      addgene_17448

      DOI: 10.7554/eLife.45572

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    ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
  69. www.jbc.org www.jbc.org
    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_17448

      DOI: 10.1074/jbc.AC119.010671

      Resource: RRID:Addgene_17448

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_17448

      What is this?

      RRID:Addgene_17448 RRIDCUR:Validated
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    jbc.org/content/294/45/16527.full