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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering Oncogenic Hotspot Mutations on SF3B1 via CRISPR-Directed PRECIS Mutagenesis
    2
    1. scibot 27 Sep 2024
      174828

      DOI: 10.1158/2767-9764.CRC-24-0145

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    2. scibot 27 Sep 2024
      174828

      DOI: 10.1158/2767-9764.CRC-24-0145

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    ncbi.nlm.nih.gov/pmc/articles/PMC11421219/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A protocol for the detection of precision genome editing in human cells using One-pot DTECT
    1
    1. scibot 27 Sep 2024
      plasmid_174828

      DOI: 10.1016/j.xpro.2024.103307

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    ncbi.nlm.nih.gov/pmc/articles/PMC11422130/
  4. Aug 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Directed evolution of hyperactive integrases for site specific insertion of transgenes
    1
    1. scibot 22 Aug 2024
      Addgene_174828

      DOI: 10.1093/nar/gkae534

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    ncbi.nlm.nih.gov/pmc/articles/PMC11317131/
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
    1
    1. scibot 02 May 2024
      Addgene: 174828

      DOI: 10.1016/j.xcrm.2024.101544

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S2666379124002349
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving prime editing with an endogenous small RNA-binding protein
    1
    1. scibot 23 Apr 2024
      174828

      DOI: 10.1038/s41586-024-07259-6

      Resource: RRID:Addgene_174828

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    ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes
    1
    1. scibot 23 Apr 2024
      Plasmid_174828

      DOI: 10.1038/s41467-024-46795-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11026479/
  11. www.sciencedirect.com www.sciencedirect.com
    Chromatin context-dependent regulation and epigenetic manipulation of prime editing
    1
    1. scibot 12 Apr 2024
      Addgene: 174828

      DOI: 10.1016/j.cell.2024.03.020

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    sciencedirect.com/science/article/pii/S0092867424003118
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo
    1
    1. scibot 11 Jan 2024
      Addgene_174828

      DOI: 10.1016/j.stem.2023.12.003

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    sciencedirect.com/science/article/pii/S1934590923004332
  14. Nov 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need
    1
    1. scibot 04 Nov 2023
      RRID:Addgene_174828

      DOI: 10.1016/j.ajhg.2023.10.005

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    sciencedirect.com/science/article/pii/S0002929723003580
  16. Sep 2023
  17. www.nature.com www.nature.com
    CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
    1
    1. scibot 20 Sep 2023
      plasmid_174828

      DOI: 10.1038/s42003-023-05052-1

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    nature.com/articles/s42003-023-05052-1
  18. Jun 2023
  19. www.nature.com www.nature.com
    Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing
    1
    1. scibot 13 Jun 2023
      RRID:Addgene_174828

      DOI: 10.1038/s41467-023-39246-2

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    nature.com/articles/s41467-023-39246-2