54 Matching Annotations
  1. Mar 2026
  2. www.sciencedirect.com www.sciencedirect.com
    STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels
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    sciencedirect.com/science/article/pii/S2211124726002615
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP9X-triggered ferroptosis mediates follicular atresia via deubiquitinating Beclin1 in chicken
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548185/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid
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    pmc.ncbi.nlm.nih.gov/articles/PMC12588028/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Crimean-Congo hemorrhagic fever virus NSm protein inhibits the type I interferon signaling by binding to STAT2
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594364/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554184/
  8. Sep 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Role of the Epstein-Barr Virus Encoded Deubiquitinating Enzyme (BPLF1) in mTOR-Mediated Cell Growth and Proliferation Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390678/
  10. Jul 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283747/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224959/
  13. Jun 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal Regulation Between the SCFFBXO24 Ubiquitin E3 Ligase and FoxP1 Protein
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154790/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase MARCH2 controls TNF-α mediated inflammation by autoubiquitination
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126869/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCFFBXO22–BACH1 complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130529/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Negative Feedback Mechanisms in the PTEN-ACE Axis: Application of Electrosorb Hydrogel-Based Gene Delivery for Intervertebral Disc Regeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160554/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12151214/
  19. May 2025
  20. elifesciences.org elifesciences.org
    SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress
    1
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    elifesciences.org/articles/97019
  21. www.sciencedirect.com www.sciencedirect.com
    HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma
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    sciencedirect.com/science/article/pii/S2211124725004917
  22. Apr 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926008/
  24. Feb 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase MAEA promotes macrophage phagocytosis and inhibits gastrointestinal cancer progression by mediating PARP1 ubiquitination and degradation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11844278/
  26. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP9X controls Wnt signaling for CNS vascular formation and barrier maintenance
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    sciencedirect.com/science/article/pii/S1534580725000292
  27. Jan 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pellino 3 E3 ligase promotes starvation-induced autophagy to prevent hepatic steatosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11740972/
  29. Sep 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 Promotes Ripretinib Resistance in Gastrointestinal Stromal Tumors by MDH2 Deubiquition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425886/
  31. www.sciencedirect.com www.sciencedirect.com
    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
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    sciencedirect.com/science/article/pii/S2211124724011070
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PITAR, a DNA damage-inducible cancer/testis long noncoding RNA, inactivates p53 by binding and stabilizing TRIM28 mRNA
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11415074/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405407/
  34. Aug 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11264351/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Skp2 contributes to sepsis-induced acute lung injury by enhancing ferroptosis through the ubiquitination of SLC3A2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335248/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBR1 promotes anaplastic thyroid carcinoma progression via stabilizing YAP through monoubiquitylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341911/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle
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    ncbi.nlm.nih.gov/pmc/articles/PMC10864110/
  39. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
  40. Jul 2024
  41. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    sciencedirect.com/science/article/pii/S1097276524004799
  42. Jun 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130243/
  44. May 2024
  45. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
  46. Apr 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncolytic Newcastle disease virus induced degradation of YAP through E3 ubiquitin ligase PRKN to exacerbate ferroptosis in tumor cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10949840/
  48. Mar 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF166 promotes colorectal cancer progression by recognizing and destabilizing poly-ADP-ribosylated angiomotins
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10937711/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926213/
  51. www.biorxiv.org www.biorxiv.org
    SIRT2-Mediated ACSS2 K271 Deacetylation Suppresses Lipogenesis Under Nutrient Stress
    1
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    biorxiv.org/content/10.1101/2024.02.27.582293v1
  52. Feb 2024
  53. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    sciencedirect.com/science/article/pii/S1097276524000480
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10795397/
  55. Dec 2023
  56. www.sciencedirect.com www.sciencedirect.com
    FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression
    1
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    sciencedirect.com/science/article/pii/S2589004223026573
  57. Nov 2023
  58. link.springer.com link.springer.com
    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
    1
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    link.springer.com/article/10.1007/s00018-023-05011-3
  59. Sep 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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    sciencedirect.com/science/article/pii/S1534580723004094
  61. Jun 2023
  62. www.sciencedirect.com www.sciencedirect.com
    KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
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    sciencedirect.com/science/article/pii/S2589004223009914
  63. Mar 2023
  64. www.sciencedirect.com www.sciencedirect.com
    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
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    sciencedirect.com/science/article/pii/S1534580723000485
  65. Dec 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis
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    sciencedirect.com/science/article/pii/S0026049522002566
  67. Mar 2022
  68. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    sciencedirect.com/science/article/pii/S2211124722000705
  69. Jan 2022
  70. www.sciencedirect.com www.sciencedirect.com
    Gentiopicroside targets PAQR3 to activate PI3K/AKT signaling pathway and ameliorate glucose and lipid metabolism
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    sciencedirect.com/science/article/pii/S2211383521004949
  71. Oct 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
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    sciencedirect.com/science/article/pii/S2211124721013747
  73. Jul 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1074761319300378
  75. Dec 2020
  76. www.mdpi.com www.mdpi.com
    Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination
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    mdpi.com/2073-4409/9/12/2547/htm
  77. Sep 2020
  78. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14853
  79. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124720309554
  80. www.sciencedirect.com www.sciencedirect.com
    OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1
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    sciencedirect.com/science/article/pii/S2211124720300243
  81. Jan 2020
  82. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
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    elifesciences.org/articles/44502
  83. link.springer.com link.springer.com
    β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
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    link.springer.com/article/10.1186/s12935-019-1029-1
  84. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1074761319300378