56 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP9X-triggered ferroptosis mediates follicular atresia via deubiquitinating Beclin1 in chicken
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548185/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12588028/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554184/
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Role of the Epstein-Barr Virus Encoded Deubiquitinating Enzyme (BPLF1) in mTOR-Mediated Cell Growth and Proliferation Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390678/
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283747/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224959/
  10. Jun 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal Regulation Between the SCFFBXO24 Ubiquitin E3 Ligase and FoxP1 Protein
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154790/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRIM21 promotes type I interferon by inhibiting the autophagic degradation of STING via p62/SQSTM1 ubiquitination in systemic lupus erythematosus: TRIM21 promotes IFN-I by inhibiting STING autophagy via p62 in SLE
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130703/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase MARCH2 controls TNF-α mediated inflammation by autoubiquitination
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126869/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Negative Feedback Mechanisms in the PTEN-ACE Axis: Application of Electrosorb Hydrogel-Based Gene Delivery for Intervertebral Disc Regeneration
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160554/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12151214/
  16. May 2025
  17. www.sciencedirect.com www.sciencedirect.com
    HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma
    1
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    sciencedirect.com/science/article/pii/S2211124725004917
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12232208/
  19. Mar 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
  21. Feb 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP9X controls Wnt signaling for CNS vascular formation and barrier maintenance
    1
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    sciencedirect.com/science/article/pii/S1534580725000292
  23. Jan 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pellino 3 E3 ligase promotes starvation-induced autophagy to prevent hepatic steatosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11740972/
  25. Sep 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 Promotes Ripretinib Resistance in Gastrointestinal Stromal Tumors by MDH2 Deubiquition
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425886/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pseudorabies Virus UL4 protein promotes the ASC-dependent inflammasome activation and pyroptosis to exacerbate inflammation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11421794/
  28. www.sciencedirect.com www.sciencedirect.com
    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
    1
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    sciencedirect.com/science/article/pii/S2211124724011070
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405407/
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11264351/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Skp2 contributes to sepsis-induced acute lung injury by enhancing ferroptosis through the ubiquitination of SLC3A2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335248/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBR1 promotes anaplastic thyroid carcinoma progression via stabilizing YAP through monoubiquitylation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341911/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10864110/
  35. 52.53.155.43 52.53.155.43
    FEBS Press
    1
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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
  36. Jul 2024
  37. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
    1
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    sciencedirect.com/science/article/pii/S1097276524004799
  38. Jun 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130243/
  40. May 2024
  41. www.sciencedirect.com www.sciencedirect.com
    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
    1
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    sciencedirect.com/science/article/pii/S2211124724006223
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-MYC impairs innate immune signaling in high-grade serous ovarian carcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095474/
  43. Apr 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncolytic Newcastle disease virus induced degradation of YAP through E3 ubiquitin ligase PRKN to exacerbate ferroptosis in tumor cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10949840/
  45. Mar 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF166 promotes colorectal cancer progression by recognizing and destabilizing poly-ADP-ribosylated angiomotins
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10937711/
  47. Feb 2024
  48. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
    1
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    sciencedirect.com/science/article/pii/S2589004224004024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10795397/
  50. Dec 2023
  51. www.sciencedirect.com www.sciencedirect.com
    FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression
    1
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    sciencedirect.com/science/article/pii/S2589004223026573
  52. Nov 2023
  53. link.springer.com link.springer.com
    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
    1
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    link.springer.com/article/10.1007/s00018-023-05011-3
  54. Sep 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
    1
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    sciencedirect.com/science/article/pii/S1534580723004094
  56. Jun 2023
  57. www.sciencedirect.com www.sciencedirect.com
    KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
    1
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    sciencedirect.com/science/article/pii/S2589004223009914
  58. Mar 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9945542/
  60. Jan 2023
  61. www.sciencedirect.com www.sciencedirect.com
    Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis
    1
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    sciencedirect.com/science/article/pii/S0026049522002566
  62. Mar 2022
  63. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
    1
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    sciencedirect.com/science/article/pii/S2211124722000705
  64. Oct 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
    1
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    sciencedirect.com/science/article/pii/S2211124721013747
  66. Jul 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
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    sciencedirect.com/science/article/pii/S1074761319300378
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6372082/
  69. Feb 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune checkpoint protein VISTA regulates antitumor immunity by controlling myeloid cell–mediated inflammation and immunosuppression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6726548/
  71. link.springer.com link.springer.com
    FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1
    1
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    link.springer.com/article/10.1186/s12964-020-00604-y
  72. Jan 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116596/
  74. Dec 2020
  75. www.mdpi.com www.mdpi.com
    Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination
    1
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    mdpi.com/2073-4409/9/12/2547/htm
  76. Sep 2020
  77. link.springer.com link.springer.com
    FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1
    1
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    link.springer.com/article/10.1186/s12964-020-00604-y
  78. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14853
  79. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124720309554
  80. www.sciencedirect.com www.sciencedirect.com
    OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1
    1
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    sciencedirect.com/science/article/pii/S2211124720300243
  81. Jan 2020
  82. www.sciencedirect.com www.sciencedirect.com
    The N-Degron Pathway Mediates ER-phagy
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    sciencedirect.com/science/article/pii/S109727651930485X
  83. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
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    elifesciences.org/articles/44502
  84. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1097276518309882
  85. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1074761319300378