51 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling
    1
    1. scibot 27 Sep 2024
      17608

      DOI: 10.1038/s44319-024-00228-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387738/
  3. www.sciencedirect.com www.sciencedirect.com
    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
    1
    1. scibot 27 Sep 2024
      Addgene_17608

      DOI: 10.1016/j.celrep.2024.114756

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    sciencedirect.com/science/article/pii/S2211124724011070
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer
    1
    1. scibot 26 Sep 2024
      17608

      DOI: 10.1038/s41467-024-50459-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11300456/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer
    2
    1. scibot 25 Sep 2024
      17608

      DOI: 10.1038/s41421-024-00715-7

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    2. scibot 25 Sep 2024
      17608

      DOI: 10.1038/s41421-024-00715-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405407/
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
    1
    1. scibot 26 Aug 2024
      17608

      DOI: 10.1002/pro.5123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11264351/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Skp2 contributes to sepsis-induced acute lung injury by enhancing ferroptosis through the ubiquitination of SLC3A2
    1
    1. scibot 26 Aug 2024
      17608

      DOI: 10.1007/s00018-024-05348-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11335248/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle
    1
    1. scibot 17 Aug 2024
      17608

      DOI: 10.1083/jcb.202308066

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864110/
  10. Jul 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3
    1
    1. scibot 25 Jul 2024
      plasmid_17608

      DOI: 10.1038/s41419-021-03444-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC7862454/
  12. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
    1
    1. scibot 24 Jul 2024
      RRID:Addgene_17608

      DOI: 10.1016/j.molcel.2024.06.001

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    sciencedirect.com/science/article/pii/S1097276524004799
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD
    1
    1. scibot 24 Jul 2024
      plasmid_17608

      DOI: 10.1093/nar/gkab834

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    ncbi.nlm.nih.gov/pmc/articles/PMC8565315/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum
    1
    1. scibot 20 Jul 2024
      RRID:Addgene_17608

      DOI: 10.7554/eLife.84798

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257679/
  15. Jun 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
    1
    1. scibot 03 Jun 2024
      17608

      DOI: 10.1038/s41467-024-48800-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11130243/
  17. May 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OTULIN-related conditions: Report of a new case and review of the literature using GenIA
    1
    1. scibot 19 May 2024
      Addgene_17608

      DOI: 10.21203/rs.3.rs-3950863/v2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11071612/
  19. Apr 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation
    1
    1. scibot 29 Apr 2024
      17608

      DOI: 10.3390/biomedicines12040755

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    ncbi.nlm.nih.gov/pmc/articles/PMC11047997/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncolytic Newcastle disease virus induced degradation of YAP through E3 ubiquitin ligase PRKN to exacerbate ferroptosis in tumor cells
    1
    1. scibot 15 Apr 2024
      17608

      DOI: 10.1128/jvi.01897-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10949840/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells
    1
    1. scibot 15 Apr 2024
      plasmid_17608

      DOI: 10.1038/s41419-024-06591-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944491/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
    1
    1. scibot 14 Apr 2024
      17608

      DOI: 10.1371/journal.ppat.1012100

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    ncbi.nlm.nih.gov/pmc/articles/PMC10994560/
  24. Mar 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF166 promotes colorectal cancer progression by recognizing and destabilizing poly-ADP-ribosylated angiomotins
    1
    1. scibot 17 Mar 2024
      17608

      DOI: 10.1038/s41419-024-06595-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10937711/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-monoubiquitylation controls VASP-mediated actin dynamics
    1
    1. scibot 08 Mar 2024
      plasmid_17608

      DOI: 10.1242/jcs.261527

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917064/
  27. Feb 2024
  28. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
    1
    1. scibot 29 Feb 2024
      Addgene17608

      DOI: 10.1016/j.isci.2024.109181

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    sciencedirect.com/science/article/pii/S2589004224004024
  29. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
    1. scibot 08 Feb 2024
      Lim et al.72Addgene, Cat# 17608

      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila
    1
    1. scibot 08 Feb 2024
      17608

      DOI: 10.1038/s41467-024-44747-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10784524/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii
    1
    1. scibot 01 Feb 2024
      17608

      DOI: 10.1186/s13567-023-01261-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10795397/
  32. Jan 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of VHL by VH298 Accelerates Pexophagy by Activation of HIF-1α in HeLa Cells
    1
    1. scibot 29 Jan 2024
      17608

      DOI: 10.3390/molecules29020482

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    ncbi.nlm.nih.gov/pmc/articles/PMC10819186/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The unusual gene architecture of polyubiquitin is created by dual-specific splice sites
    1
    1. scibot 28 Jan 2024
      plasmid_17

      DOI: 10.1186/s13059-023-03157-8

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      RRID:Addgene_17608 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC10809524/
  35. Dec 2023
  36. www.sciencedirect.com www.sciencedirect.com
    FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression
    1
    1. scibot 21 Dec 2023
      RRID:Addgene_17608

      DOI: 10.1016/j.isci.2023.108580

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    sciencedirect.com/science/article/pii/S2589004223026573
  37. Aug 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-monoubiquitination controls VASP-mediated actin dynamics
    1
    1. scibot 03 Aug 2023
      RRID:Addgene_17608

      DOI: 10.1101/2023.07.16.549237

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    ncbi.nlm.nih.gov/pmc/articles/PMC10370145/
  39. Jul 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
    1
    1. scibot 01 Jul 2023
      RRID:Addgene_17608

      DOI: 10.1016/j.chom.2023.05.030

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    sciencedirect.com/science/article/pii/S1931312823002238
  41. Apr 2023
  42. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
    1
    1. scibot 08 Apr 2023
      RRID:Addgene_17608

      DOI: 10.1016/j.xcrm.2023.101007

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    sciencedirect.com/science/article/pii/S2666379123001179
  43. Mar 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
    1
    1. scibot 09 Mar 2023
      RRID:Addgene_17608

      DOI: 10.1016/j.isci.2023.106150

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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
  45. www.sciencedirect.com www.sciencedirect.com
    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
    1
    1. scibot 03 Mar 2023
      RRID:Addgene_17608

      DOI: 10.1016/j.devcel.2023.02.006

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    sciencedirect.com/science/article/pii/S1534580723000485
  46. Dec 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis
    1
    1. scibot 18 Dec 2022
      RRID:Addgene_17608

      DOI: 10.1016/j.metabol.2022.155378

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    sciencedirect.com/science/article/pii/S0026049522002566
  48. Jul 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
    1
    1. scibot 13 Jul 2022
      AddgeneCat# 17608

      DOI: 10.1016/j.celrep.2022.111070

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    sciencedirect.com/science/article/pii/S2211124722008683
  50. Jun 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Stub1 maintains proteostasis of master transcription factors in embryonic stem cells
    1
    1. scibot 09 Jun 2022
      AddgeneCat#17608

      DOI: 10.1016/j.celrep.2022.110919

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    sciencedirect.com/science/article/pii/S2211124722006969
  52. Mar 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity
    1
    1. scibot 18 Mar 2022
      plasmid_17608

      DOI: 10.1083/jcb.202010065

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    ncbi.nlm.nih.gov/pmc/articles/PMC8919618/
  54. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
    1
    1. scibot 04 Mar 2022
      RRID:Addgene_17608

      DOI: 10.1016/j.celrep.2022.110354

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    sciencedirect.com/science/article/pii/S2211124722000705
  55. Jan 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Gentiopicroside targets PAQR3 to activate PI3K/AKT signaling pathway and ameliorate glucose and lipid metabolism
    1
    1. scibot 07 Jan 2022
      RRID:Addgene_17608

      DOI: 10.1016/j.apsb.2021.12.023

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    sciencedirect.com/science/article/pii/S2211383521004949
  57. Oct 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
    1
    1. scibot 30 Oct 2021
      plasmid_17608

      DOI: 10.1016/j.celrep.2021.109904

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    sciencedirect.com/science/article/pii/S2211124721013747
  59. www.sciencedirect.com www.sciencedirect.com
    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
    1
    1. scibot 27 Oct 2021
      Addgene_17608

      DOI: 10.1016/j.celrep.2021.109888

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    sciencedirect.com/science/article/pii/S2211124721013589
  60. Jul 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:Addgene_17608

      DOI: 10.1016/j.immuni.2019.01.014

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      Curator: @ethanbadger

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      RRID:Addgene_17608 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319300378
  62. www.nature.com www.nature.com
    Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
    1
    1. scibot 28 Jul 2021
      pRK5-HA-Ubiquitin

      DOI: 10.1038/s41467-019-09800-y

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    nature.com/articles/s41467-019-09800-y
  63. Jun 2021
  64. www.sciencedirect.com www.sciencedirect.com
    TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity
    1
    1. scibot 02 Jun 2021
      Addgene_17608

      DOI: 10.1016/j.cell.2021.04.047

      Resource: RRID:Addgene_17608

      Curator: @scibot

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608
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    sciencedirect.com/science/article/pii/S0092867421005821
  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development
    1
    1. scibot 05 May 2021
      Addgene_17608

      DOI: 10.1016/j.devcel.2020.08.012

      Resource: RRID:Addgene_17608

      Curator: @scibot

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608
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    sciencedirect.com/science/article/pii/S1534580720306705
  67. Jan 2021
  68. www.sciencedirect.com www.sciencedirect.com
    DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks
    1
    1. scibot 05 Jan 2021
      pRK5-HA-Ubiquitin-WT

      DOI: 10.1016/j.celrep.2020.108569

      Resource: RRID:Addgene_17608

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720315588
  69. Dec 2020
  70. www.mdpi.com www.mdpi.com
    Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination
    1
    1. scibot 07 Dec 2020
      pRK5-HA-Ubiquitin-WT

      DOI: 10.3390/cells9122547

      Resource: RRID:Addgene_17608

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608 RRIDCUR:Missing
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    mdpi.com/2073-4409/9/12/2547/htm
  71. Sep 2020
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance
    1
    1. scibot 11 Sep 2020
      RRID:Addgene_17608

      DOI: 10.1083/jcb.201902088

      Resource: RRID:Addgene_17608

      Curator: @evieth

      SciCrunch record: RRID:Addgene_17608

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      RRIDCUR:Validated RRID:Addgene_17608
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    ncbi.nlm.nih.gov/pmc/articles/PMC7039193/
  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_17608

      DOI: 10.1111/bph.14853

      Resource: RRID:Addgene_17608

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      RRIDCUR:Validated RRID:Addgene_17608
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14853
  74. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
    1
    1. scibot 04 Sep 2020
      RRID:Addgene_17608

      DOI: 10.1016/j.celrep.2020.107974

      Resource: RRID:Addgene_17608

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720309554
  75. Jan 2020
  76. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_17608

      DOI: 10.7554/eLife.44502

      Resource: RRID:Addgene_17608

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_17608

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      RRID:Addgene_17608 RRIDCUR:Validated
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    elifesciences.org/articles/44502
  77. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_17608

      DOI: 10.1016/j.immuni.2019.01.014

      Resource: RRID:Addgene_17608

      Curator: @ethanbadger

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      RRID:Addgene_17608 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761319300378