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Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling

1
1. scibot 07 Oct 2026
  
  in Public
  
  Addgene plasmid 17662
  
  DOI: 10.1242/jcs.264494
  
  Resource: RRID:Addgene_17662
  
  Curator: @mpairish
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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pmc.ncbi.nlm.nih.gov/articles/PMC12863304/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Selection of specific and efficient siRNAs in new cellular model for Hutchinson-Gilford progeria syndrome therapy

1
1. scibot 24 Nov 2025
  
  in Public
  
  17662
  
  DOI: 10.1016/j.omtn.2025.102727
  
  Resource: RRID:Addgene_17662
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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RRID:Addgene_17662

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pmc.ncbi.nlm.nih.gov/articles/PMC12554022/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nuclear deformability increases PARPi sensitivity in BRCA1-deficient cells by increasing microtubule-dependent DNA break mobility

1
1. scibot 20 Jul 2025
  
  in Public
  
  Addgene_17662
  
  DOI: 10.1038/s41467-025-60756-8
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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RRID:Addgene_17662

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12174318/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Viscoelastic extracellular matrix enhances epigenetic remodeling and cellular plasticity

1
1. scibot 17 May 2025
  
  in Public
  
  17662
  
  DOI: 10.1038/s41467-025-59190-7
  
  Resource: RRID:Addgene_17662
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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pmc.ncbi.nlm.nih.gov/articles/PMC12043949/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Excess surface area of the nuclear lamina enables unhindered cell migration through constrictions

1
1. scibot 07 Apr 2025
  
  in Public
  
  plasmid_17662
  
  DOI: 10.1126/sciadv.ads6573
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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pmc.ncbi.nlm.nih.gov/articles/PMC11952090/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair

1
1. scibot 28 Sep 2024
  
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  17662
  
  DOI: 10.1083/jcb.202307142
  
  Resource: RRID:Addgene_17662
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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ncbi.nlm.nih.gov/pmc/articles/PMC11329780/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Indentation induces instantaneous nuclear stiffening and unfolding of nuclear envelop wrinkles

1
1. scibot 03 Mar 2024
  
  in Public
  
  RRID:Addgene_17662
  
  DOI: 10.1073/pnas.2307356120
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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ncbi.nlm.nih.gov/pmc/articles/PMC10483616/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cholesterol biosynthetic pathway induces cellular senescence through ERRα

1
1. scibot 05 Feb 2024
  
  in Public
  
  Addgene_17662
  
  DOI: 10.1038/s41514-023-00128-y
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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ncbi.nlm.nih.gov/pmc/articles/PMC10786911/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate

1
1. scibot 13 Feb 2022
  
  in Public
  
  Addgene_17662
  
  DOI: 10.1016/j.devcel.2022.01.015
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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sciencedirect.com/science/article/pii/S1534580722000405
Jan 2022
www.sciencedirect.com www.sciencedirect.com

miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence

1
1. scibot 26 Jan 2022
  
  in Public
  
  plasmid_17662
  
  DOI: 10.1016/j.isci.2022.103757
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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sciencedirect.com/science/article/pii/S258900422200027X
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lamin A/C Mechanosensor Drives Tumor Cell Aggressiveness and Adhesion on Substrates With Tissue-Specific Elasticity

2
1. scibot 30 Sep 2021
  
  in Public
  
  RRID:Addgene_17662
  
  DOI: 10.3389/fcell.2021.712377
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
2. scibot 30 Sep 2021
  
  in Public
  
  plasmid_176621
  
  DOI: 10.3389/fcell.2021.712377
  
  Resource: RRID:Addgene_17662
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRIDCUR:NotRRID RRID:Addgene_17662 RRIDCUR:Unresolved
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RRIDCUR:Unresolved

RRID:Addgene_17662

RRIDCUR:NotRRID

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8476891/
Feb 2021
www.molbiolcell.org www.molbiolcell.org

BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:Addgene_17662
  
  DOI: 10.1091/mbc.E20-01-0009
  
  Resource: RRID:Addgene_17662
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_17662
  
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  RRID:Addgene_17662
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molbiolcell.org/doi/abs/10.1091/mbc.E20-01-0009
Oct 2020
elifesciences.org elifesciences.org

PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly

1
1. scibot 13 Oct 2020
  
  in Public
  
  Addgene_17662
  
  DOI: 10.7554/eLife.59510
  
  Resource: RRID:Addgene_17662
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_17662
  
  What is this?
  
  RRID:Addgene_17662 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_17662

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scibot

URL

elifesciences.org/articles/59510
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:Addgene_17662
  
  DOI: 10.1242/jcs.240416
  
  Resource: RRID:Addgene_17662
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_17662
  
  What is this?
  
  RRID:Addgene_17662 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_17662

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7272351/