Hypothesis

39 Matching Annotations

Apr 2026
54.241.53.176 54.241.53.176

hallam-et-al-2026-bdnf-alters--cleavage-of-app-and-subcellular-distribution-of-bace1-html.html

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1. scibot 02 Apr 2026
  
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  1817
  
  DOI: 10.3389/neuro.02.001.2010
  
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54.241.53.176/38bfe47aa6d994e49b5dc7d9c260af15691d6cd8/hallam-et-al-2026-bdnf-alters--cleavage-of-app-and-subcellular-distribution-of-bace1-html.html
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A pH-driven receptor switch from ACE2 to NPC1 enables endosomal entry of SARS-CoV-2

1
1. scibot 27 Mar 2026
  
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  Addgene_1817
  
  DOI: 10.21203/rs.3.rs-8437418/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12997109/
Jan 2026
www.nature.com www.nature.com

Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles

1
1. scibot 15 Jan 2026
  
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  RRID:Addgene_1817
  
  DOI: 10.1038/s41467-025-68160-y
  
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nature.com/articles/s41467-025-68160-y
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation

1
1. scibot 23 Nov 2025
  
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  1817
  
  DOI: 10.1083/jcb.202404018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12459091/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Real-time monitoring of secretory protein traffic for investigating trafficking regulators of ACE2 in living cells

1
1. scibot 22 Sep 2025
  
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  addgene_1817
  
  DOI: 10.1016/j.jbc.2025.110593
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12446517/
www.sciencedirect.com www.sciencedirect.com

Inositol (1,4,5)-trisphosphate 5-phosphatase promotes survival of uveal melanoma by regulating oncogenic G protein–driven calcium oscillations

1
1. scibot 09 Sep 2025
  
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  Addgene_1817
  
  DOI: 10.1016/j.jbc.2025.110589
  
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sciencedirect.com/science/article/pii/S0021925825024408
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

1
1. scibot 06 Sep 2025
  
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  1817
  
  DOI: 10.1002/advs.202502931
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12376557/
www.tandfonline.com www.tandfonline.com

Impaired MAPT/tau-secretory lysosomes are linked to cognitive vulnerability in Alzheimer patients

1
1. scibot 03 Sep 2025
  
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  Addgene, 1817
  
  DOI: 10.1080/15548627.2025.2552905
  
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tandfonline.com/doi/full/10.1080/15548627.2025.2552905
Aug 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation

1
1. scibot 27 Aug 2025
  
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  plasmid_1817
  
  DOI: 10.1111/febs.70230
  
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febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70230
www.sciencedirect.com www.sciencedirect.com

Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.

1
1. scibot 21 Aug 2025
  
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  RRID:Addgene_1817
  
  DOI: 10.1016/j.ejphar.2025.178082
  
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sciencedirect.com/science/article/pii/S0014299925008362
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage

1
1. scibot 11 Apr 2025
  
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  RRID: Addgene 1817
  
  DOI: 10.1038/s41556-025-01653-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12081312/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The inter-organelle cross-talk finely orchestrated in the amyloidogenic processing of amyloid precursor protein in dendritic arborization neurons of Drosophila

1
1. scibot 23 Mar 2025
  
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  plasmid_1817
  
  DOI: 10.7150/thno.104345
  
  Resource: RRID:Addgene_1817
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11898278/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Palmitoylation regulates myelination by modulating the ZDHHC3-Cadm4 axis in the central nervous system

1
1. scibot 29 Sep 2024
  
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  1817
  
  DOI: 10.1038/s41392-024-01971-5
  
  Resource: RRID:Addgene_1817
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11427461/
www.biorxiv.org www.biorxiv.org

Examination of INPP5A in uveal melanoma uncovers novel calcium transients

1
1. scibot 27 Sep 2024
  
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  Addgene_1817
  
  DOI: 10.1101/2024.09.18.613756
  
  Resource: RRID:Addgene_1817
  
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biorxiv.org/content/10.1101/2024.09.18.613756v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A genetically-encoded fluorescence-based reporter to spatiotemporally investigate mannose-6-phosphate pathway

1
1. scibot 27 Sep 2024
  
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  plasmid_1817
  
  DOI: 10.1091/mbc.E23-09-0344
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321044/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers

1
1. scibot 18 Aug 2024
  
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  1817
  
  DOI: 10.1172/JCI177142
  
  Resource: RRID:Addgene_1817
  
  Curator: @olekpark
  
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  RRID:Addgene_1817
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ncbi.nlm.nih.gov/pmc/articles/PMC11291269/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

1
1. scibot 30 Jun 2024
  
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  Addgene_1817
  
  DOI: 10.1101/2024.04.02.587808
  
  Resource: RRID:Addgene_1817
  
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  RRID:Addgene_1817
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ncbi.nlm.nih.gov/pmc/articles/PMC11188082/
May 2024
www.biorxiv.org www.biorxiv.org

Oligomerization and cellular localization of SLC26A11

2
1. scibot 23 May 2024
  
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  plasmid_1817
  
  DOI: 10.1101/2024.04.29.591613
  
  Resource: RRID:Addgene_1817
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_1817
  
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  RRID:Addgene_1817
2. scibot 23 May 2024
  
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  plasmid_1817
  
  DOI: 10.1101/2024.04.29.591613
  
  Resource: RRID:Addgene_1817
  
  Curator: @scibot
  
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  RRID:Addgene_1817
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biorxiv.org/content/10.1101/2024.04.29.591613v1
www.biorxiv.org www.biorxiv.org

Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

1
1. scibot 23 May 2024
  
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  plasmid_1817
  
  DOI: 10.1101/2024.05.16.594502
  
  Resource: RRID:Addgene_1817
  
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biorxiv.org/content/10.1101/2024.05.16.594502v1
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons

1
1. scibot 21 Feb 2024
  
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  1817
  
  DOI: 10.1083/jcb.202304042
  
  Resource: RRID:Addgene_1817
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10868123/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Methionine sulfoxide reductases and cholesterol transporter STARD3 constitute an efficient system for detoxification of cholesterol hydroperoxides

1
1. scibot 07 Sep 2023
  
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  RRID:Addgene_1817
  
  DOI: 10.1016/j.jbc.2023.105099
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10469991/
Jun 2023
rupress.org rupress.org

Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C

1
1. scibot 22 Jun 2023
  
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  RRID:Addgene_1817
  
  DOI: 10.1083/jcb.202208121
  
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rupress.org/jcb/article/222/8/e202208121/214174/Zn2-decoration-of-microtubules-arrests-axonal
Jan 2023
www.sciencedirect.com www.sciencedirect.com

The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

1
1. scibot 27 Jan 2023
  
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  plasmid_1817
  
  DOI: 10.1016/j.celrep.2023.112037
  
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sciencedirect.com/science/article/pii/S2211124723000487
Apr 2022
www.jneurosci.org www.jneurosci.org

CLC Anion/Proton Exchangers Regulate Secretory Vesicle Filling and Granule Exocytosis in Chromaffin Cells

1
1. scibot 14 Apr 2022
  
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  RRID:Addgene_1817
  
  DOI: 10.1523/JNEUROSCI.2439-21.2022
  
  Resource: RRID:Addgene_1817
  
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jneurosci.org/content/42/15/3080
Mar 2022
www.nature.com www.nature.com

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

1
1. scibot 26 Mar 2022
  
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  Addgene_1817
  
  DOI: 10.1038/s41467-022-28952-y
  
  Resource: RRID:Addgene_1817
  
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nature.com/articles/s41467-022-28952-y
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability

1
1. scibot 17 Aug 2021
  
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  Addgene_1817
  
  DOI: 10.1038/s41467-021-24713-5
  
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  RRID:Addgene_1817
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ncbi.nlm.nih.gov/pmc/articles/PMC8302662/
www.sciencedirect.com www.sciencedirect.com

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

1
1. scibot 10 Aug 2021
  
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  Addgene_1817
  
  DOI: 10.1016/j.cub.2018.11.065
  
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sciencedirect.com/science/article/pii/S0960982218315951
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 30 Jul 2021
  
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  RRID:Addgene_1817
  
  DOI: 10.1016/j.cell.2018.11.030
  
  Resource: RRID:Addgene_1817
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6333918/
elifesciences.org elifesciences.org

Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72

1
1. scibot 29 Jul 2021
  
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  Addgene plasmid #1817
  
  DOI: 10.7554/eLife.48363
  
  Resource: RRID:Addgene_1817
  
  Curator: @Naa003
  
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  RRID:Addgene_1817 RRIDCUR:Unrecognized
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elifesciences.org/articles/48363
May 2021
www.sciencedirect.com www.sciencedirect.com

Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy

1
1. scibot 20 May 2021
  
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  Addgene_1817
  
  DOI: 10.1016/j.nbd.2021.105400
  
  Resource: RRID:Addgene_1817
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S0969996121001492
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes

1
1. scibot 26 Mar 2021
  
  in Public
  
  Addgene_1817
  
  DOI: 10.1016/j.cub.2021.02.061
  
  Resource: RRID:Addgene_1817
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_1817
  
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  RRIDCUR:Validated RRID:Addgene_1817
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RRIDCUR:Validated

RRID:Addgene_1817

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sciencedirect.com/science/article/pii/S0960982221003055
Feb 2021
www.cell.com www.cell.com

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:Addgene_1817
  
  DOI: 10.1016/j.cell.2018.11.030
  
  Resource: RRID:Addgene_1817
  
  Curator: @scibot
  
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  RRID:Addgene_1817
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cell.com/cell/abstract/S0092-8674(18)31555-1
Sep 2020
www.life-science-alliance.org www.life-science-alliance.org

Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase

1
1. scibot 26 Sep 2020
  
  in Public
  
  plasmid_1817
  
  DOI: 10.26508/lsa.201800118
  
  Resource: RRID:Addgene_1817
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_1817
  
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  RRIDCUR:Validated RRID:Addgene_1817
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RRIDCUR:Validated

RRID:Addgene_1817

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life-science-alliance.org/content/1/6/e201800118
jcs.biologists.org jcs.biologists.org

Basal-type lumenogenesis by extraembryonic endoderm stem cells models the early visceral endoderm

1
1. scibot 04 Sep 2020
  
  in Public
  
  Lamp1-RFP
  
  DOI: 10.1242/jcs.230607
  
  Resource: RRID:Addgene_1817
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_1817
  
  Curator comments: Lamp1-RFP
  
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  RRID:Addgene_1817 RRIDCUR:Missing
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jcs.biologists.org/content/132/19/jcs230607
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Endocytic sorting and downregulation of the M2 acetylcholine receptor is regulated by ubiquitin and the ESCRT complex

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_1817
  
  DOI: 10.1016/j.neuropharm.2019.107828
  
  Resource: RRID:Addgene_1817
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_1817
  
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  RRID:Addgene_1817 RRIDCUR:Validated
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RRID:Addgene_1817

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scibot

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sciencedirect.com/science/article/pii/S0028390819303946
www.sciencedirect.com www.sciencedirect.com

Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_1817
  
  DOI: 10.1016/j.cmet.2019.03.005
  
  Resource: RRID:Addgene_1817
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_1817
  
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  RRID:Addgene_1817 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_1817

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119301330
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  plasmid_1817
  
  DOI: 10.26508/lsa.201800118
  
  Resource: RRID:Addgene_1817
  
  Curator: @evieth
  
  SciCrunch record: plasmid_1817
  
  What is this?
  
  RRID:Addgene_1817 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_1817

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6312924/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:Addgene_1817
  
  DOI: 10.1016/j.cell.2018.11.030
  
  Resource: RRID:Addgene_1817
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_1817
  
  What is this?
  
  RRID:Addgene_1817 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_1817

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418315551