45 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-mediated regulation of APE2 protein abundance
    1
    1. scibot 07 May 2024
      plasmid_18712

      DOI: 10.1016/j.jbc.2024.107337

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    sciencedirect.com/science/article/pii/S0021925824018386
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells
    1
    1. scibot 15 Apr 2024
      18712

      DOI: 10.1007/s00018-024-05187-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948558/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of proteasome subunit PSMD1 induces cancer cell death via protein ubiquitination and DNA damage, irrespective of p53 status
    1
    1. scibot 13 Apr 2024
      plasmid_18712

      DOI: 10.1038/s41598-024-58215-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10997673/
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CRL5–SPSB3 ubiquitin ligase targets nuclear cGAS for degradation
    1
    1. scibot 31 Mar 2024
      18712

      DOI: 10.1038/s41586-024-07112-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10972748/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MARCH2, a novel oncogene-regulated SNAIL E3 ligase, suppresses triple negative breast cancer metastases
    1
    1. scibot 31 Mar 2024
      RRID:Addgene_18712

      DOI: 10.1158/2767-9764.CRC-23-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC10977041/
  9. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
    1
    1. scibot 21 Mar 2024
      RRID:Addgene_18712

      DOI: 10.1101/2024.03.03.583221

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    biorxiv.org/content/10.1101/2024.03.03.583221v1
  10. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated acetylation of UHRF1 enhances UHRF1 E3 ligase activity to facilitate DNA methylation maintenance
    1
    1. scibot 06 Mar 2024
      RRID:Addgene_18712

      DOI: 10.1016/j.celrep.2024.113908

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    sciencedirect.com/science/article/pii/S2211124724002365
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
    1
    1. scibot 01 Mar 2024
      plasmid_18712

      DOI: 10.1038/s44318-023-00018-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897158/
  12. Feb 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 ORF7a Mutation Found in BF.5 and BF.7 Sublineages Impacts Its Functions
    1
    1. scibot 28 Feb 2024
      18712

      DOI: 10.3390/ijms25042351

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889720/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation
    1
    1. scibot 13 Feb 2024
      18712

      DOI: 10.21203/rs.3.rs-2531119/v2

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    ncbi.nlm.nih.gov/pmc/articles/PMC9915899/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies
    1
    1. scibot 13 Feb 2024
      HA-Ubiquitin

      DOI: 10.1038/s41418-023-01251-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850161/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma
    1
    1. scibot 01 Feb 2024
      18712

      DOI: 10.1186/s12964-023-01366-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10795333/
  17. Jan 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin-specific Protease 35 Promotes Gastric Cancer Metastasis by Increasing the Stability of Snail1
    1
    1. scibot 30 Jan 2024
      plasmid_18712

      DOI: 10.7150/ijbs.87176

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    ncbi.nlm.nih.gov/pmc/articles/PMC10797686/
  19. Sep 2023
  20. www.sciencedirect.com www.sciencedirect.com
    USP13 deubiquitinates p62/SQSTM1 to induce autophagy and Nrf2 release for activating antioxidant response genes
    1
    1. scibot 30 Sep 2023
      RRID:Addgene_18712

      DOI: 10.1016/j.freeradbiomed.2023.09.024

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    sciencedirect.com/science/article/pii/S0891584923006482
  21. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
    1
    1. scibot 08 Sep 2023
      plasmid_18712

      DOI: 10.1016/j.devcel.2023.08.013

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    sciencedirect.com/science/article/pii/S1534580723004094
  22. Aug 2023
  23. 52.53.155.43 52.53.155.43
    FEBS Press
    1
    1. scibot 03 Aug 2023
      Plasmid_18712

      DOI: 10.1002/1878-0261.13497

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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
  24. Jul 2023
  25. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
    1
    1. scibot 08 Jul 2023
      RRID:Addgene_18712

      DOI: 10.1038/s41392-023-01458-9

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    nature.com/articles/s41392-023-01458-9
  26. Jun 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes
    2
    1. scibot 14 Jun 2023
      plasmid_18712

      DOI: 10.3389/fonc.2023.1197542

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      RRID:Addgene_18712
    2. scibot 14 Jun 2023
      plasmid_18712

      DOI: 10.3389/fonc.2023.1197542

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    ncbi.nlm.nih.gov/pmc/articles/PMC10258340/
  28. Dec 2022
  29. link.springer.com link.springer.com
    USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity
    1
    1. scibot 31 Dec 2022
      RRID:Addgene_18712

      DOI: 10.1186/s10020-022-00596-0

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    link.springer.com/article/10.1186/s10020-022-00596-0
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation
    1
    1. scibot 02 Dec 2022
      plasmid_18712

      DOI: 10.1016/j.jbc.2022.102597

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    ncbi.nlm.nih.gov/pmc/articles/PMC9691929/
  31. Nov 2022
  32. www.nature.com www.nature.com
    Tautomycin and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer
    1
    1. scibot 30 Nov 2022
      plasmid_18712

      DOI: 10.1038/s41420-022-01257-1

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    nature.com/articles/s41420-022-01257-1
  33. Oct 2022
  34. www.cell.com www.cell.com
    X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
    1
    1. scibot 05 Oct 2022
      Plasmid_18712

      DOI: 10.1016/j.cell.2022.09.002

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    cell.com/cell/fulltext/S0092-8674(22)01124-2
  35. Sep 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett’s-associated esophageal adenocarcinomas
    1
    1. scibot 03 Sep 2022
      plasmid_18

      DOI: 10.1186/s13046-022-02472-5

      Resource: RRID:Addgene_18712

      Curator: @evieth

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      RRID:Addgene_18712 RRIDCUR:Unresolved
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    ncbi.nlm.nih.gov/pmc/articles/PMC9434868/
  37. Aug 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
    1
    1. scibot 26 Aug 2022
      RRID:Addgene_18712

      DOI: 10.1126/sciadv.abo5633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9348805/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1
    1
    1. scibot 22 Aug 2022
      RRID:Addgene_18712

      DOI: 10.3390/molecules27154867

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    ncbi.nlm.nih.gov/pmc/articles/PMC9369648/
  40. Apr 2022
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 05 Apr 2022
      RRID:Addgene_18712

      DOI: 10.1111/bph.15763

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763
  42. Mar 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IBtkα Activates the β-Catenin-Dependent Transcription of MYC through Ubiquitylation and Proteasomal Degradation of GSK3β in Cancerous B Cells
    1
    1. scibot 04 Mar 2022
      RRID:Addgene_18712

      DOI: 10.3390/ijms23042044

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    ncbi.nlm.nih.gov/pmc/articles/PMC8875111/
  44. Dec 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development
    1
    1. scibot 11 Dec 2021
      Addgene plasmid# 18712

      DOI: 10.1016/j.isci.2021.103484

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2589004221014553
  46. www.sciencedirect.com www.sciencedirect.com
    CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
    1
    1. scibot 11 Dec 2021
      Addgene_18712

      DOI: 10.1016/j.isci.2021.103538

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    sciencedirect.com/science/article/pii/S2589004221015091
  47. Sep 2021
  48. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
    1
    1. scibot 24 Sep 2021
      18712

      DOI: 10.1016/j.molcel.2021.08.039

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      RRID:Addgene_18712 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276521007292
  49. Aug 2021
  50. academic.oup.com academic.oup.com
    Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6
    2
    1. scibot 15 Aug 2021
      plasmid_18712

      DOI: 10.1093/cercor/bhab242

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      RRID:Addgene_18712
    2. scibot 10 Aug 2021
      RRID:Addgene_18

      DOI: 10.1093/cercor/bhab242

      Resource: RRID:Addgene_18712

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_18712

      Curator comments: HA-Ubiquitin

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      RRIDCUR:SyntaxError RRID:Addgene_18712 RRIDCUR:Unresolved
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    academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhab242/6338536
  51. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 06 Aug 2021
      Plasmid_18712

      DOI: 10.1016/j.celrep.2018.11.025

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    sciencedirect.com/science/article/pii/S2211124718317716
  52. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
    1
    1. scibot 03 Aug 2021
      plasmid_18712

      DOI: 10.1016/j.chom.2018.11.001

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    sciencedirect.com/science/article/pii/S1931312818305584
  53. Jul 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation
    1
    1. scibot 29 Jul 2021
      Addgene #18712

      DOI: 10.1016/j.celrep.2019.09.039

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      Curator: @ethanbadger

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      RRID:Addgene_18712 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S2211124719312276
  55. www.sciencedirect.com www.sciencedirect.com
    Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
    1
    1. scibot 29 Jul 2021
      Addgene#18712

      DOI: 10.1016/j.molcel.2019.07.013

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      RRID:Addgene_18712 RRIDCUR:Unrecognized
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    sciencedirect.com/science/article/pii/S109727651930543X
  56. rupress.org rupress.org
    TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity
    1
    1. scibot 24 Jul 2021
      RRID:Addgene_18712

      DOI: 10.1083/jcb.202010180

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    rupress.org/jcb/article/220/7/e202010180/212098/TRIM37-prevents-formation-of-condensate-organized
  57. May 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function
    1
    1. scibot 14 May 2021
      RRID:Addgene_18712

      DOI: 10.1038/s41419-021-03697-6

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      RRID:Addgene_18712
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    ncbi.nlm.nih.gov/pmc/articles/PMC8113371/
  59. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    1. scibot 07 May 2021
      plasmid_18712

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  60. Feb 2021
  61. www.sciencedirect.com www.sciencedirect.com
    mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR
    1
    1. scibot 27 Feb 2021
      Addgene_18712

      DOI: 10.1016/j.celrep.2020.108564

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    sciencedirect.com/science/article/pii/S2211124720315539
  62. Jan 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression
    1
    1. scibot 20 Jan 2021
      RRID: Addgene_18712

      DOI: 10.1158/0008-5472.CAN-20-1871

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      Curator: @evieth

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      RRID:Addgene_18712
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    ncbi.nlm.nih.gov/pmc/articles/PMC7116596/
  64. Sep 2020
  65. www.nature.com www.nature.com
    TRIM37 controls cancer-specific vulnerability to PLK4 inhibition
    1
    1. scibot 15 Sep 2020
      RRID:Addgene_18712

      DOI: 10.1038/s41586-020-2710-1

      Resource: RRID:Addgene_18712

      Curator: @evieth

      SciCrunch record: RRID:Addgene_18712

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      RRIDCUR:Validated RRID:Addgene_18712
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    nature.com/articles/s41586-020-2710-1
  66. www.sciencedirect.com www.sciencedirect.com
    OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1
    1
    1. scibot 03 Sep 2020
      Addgene Plasmid 18712

      DOI: 10.1016/j.celrep.2020.01.015

      Resource: RRID:Addgene_18712

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_18712

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      RRID:Addgene_18712
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    sciencedirect.com/science/article/pii/S2211124720300243
  67. Jan 2020
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication
    1
    1. scibot 13 Jan 2020
      Plasmid_18712

      DOI: 10.1016/j.celrep.2018.11.025

      Resource: RRID:Addgene_18712

      Curator: @evieth

      SciCrunch record: Plasmid_18712

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      RRID:Addgene_18712 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6814291/