58 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.
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    sciencedirect.com/science/article/pii/S0014299925008362
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H3K36me2 methyltransferase NSD2/WHSC1 promotes triple-negative breast cancer metastasis via activation of ULK1-dependent autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283020/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ANKZF1 helps to eliminate stress-damaged mitochondria by LC3-mediated mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307761/
  5. Jul 2025
  6. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70094
  7. Jun 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ESRRA (estrogen related receptor, alpha) induces ribosomal protein RPLP1-mediated adaptive hepatic translation during prolonged starvation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087656/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synthesis, Structure–Activity Relationship, and Biological Evaluation of a Novel Malabaricone Derivative: A Potent Anticancer Agent and Radiosensitizer That Targets Autophagy Flux
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    pmc.ncbi.nlm.nih.gov/articles/PMC12138602/
  10. May 2025
  11. www.tandfonline.com www.tandfonline.com
    MCOLN1/TRPML1-MCOLN3/TRPML3 heteromer and its coupling to Ca2+ sensor SYT5 regulates autophagosome-lysosome fusion in a PtdIns4P-dependent manner
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    tandfonline.com/doi/abs/10.1080/15548627.2025.2510846
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young‐Onset PLA2G6 Parkinson's Disease iPSCs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11973445/
  13. Apr 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952844/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958763/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE4 impairs autophagy and Aβ clearance by microglial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958439/
  17. Mar 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of Pancreatic Neuroendocrine Neoplastic Cell Fate by Autophagy-Mediated Death
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    pmc.ncbi.nlm.nih.gov/articles/PMC11905116/
  19. Jan 2025
  20. www.sciencedirect.com www.sciencedirect.com
    Ca2+/calmodulin-dependent protein kinase II β decodes ER Ca2+ transients to trigger autophagosome formation
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    sciencedirect.com/science/article/pii/S1097276524010001
  21. www.sciencedirect.com www.sciencedirect.com
    Andrographolide mitigates neurotoxicity induced by lipopolysaccharide or amyloid-β through modulation of miR-222-mediated p62 and NF-κBp65 expression
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    sciencedirect.com/science/article/pii/S0014299924009142
  22. Dec 2024
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TIGAR coordinates senescence-associated secretory phenotype via lysosome repositioning and α-tubulin deacetylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671532/
  24. Sep 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CTCF and BORIS-mediated autophagy regulation via alternative splicing of BNIP3L in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11254729/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343278/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  28. Aug 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127954/
  30. Jul 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress by D2-HG
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    sciencedirect.com/science/article/pii/S2212877824001005
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9976989/
  33. Jun 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 Tat-Mediated Human Müller Glial Cell Senescence Involves Endoplasmic Reticulum Stress and Dysregulated Autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209317/
  35. Feb 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10859382/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olanzapine, risperidone and ziprasidone differently affect lysosomal function and autophagy, reflecting their different metabolic risk in patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774340/
  38. Dec 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative Analysis of Autophagy in Single Cells: Differential Response to Amino Acid and Glucose Starvation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10705537/
  40. link.springer.com link.springer.com
    Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway
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    link.springer.com/article/10.1186/s12906-023-04290-4
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
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    sciencedirect.com/science/article/pii/S2211124723011956
  43. Sep 2023
  44. link.springer.com link.springer.com
    Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors
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    link.springer.com/article/10.1007/s11357-023-00938-8
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    sciencedirect.com/science/article/pii/S2211124723008185
  47. Jun 2023
  48. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
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    sciencedirect.com/science/article/pii/S2589004223011951
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10264968/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
  51. May 2023
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.935
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal Patterns of Substance P-Bound MRGPRX2 Reveal a Novel Connection Between Macropinosome Resolution and Secretory Granule Regeneration in Mast Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9273857/
  54. Mar 2023
  55. www.tandfonline.com www.tandfonline.com
    Synergic induction of autophagic cell death in anaplastic thyroid carcinoma
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    tandfonline.com/doi/abs/10.1080/07357907.2023.2183027
  56. Oct 2022
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages
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    onlinelibrary.wiley.com/doi/10.1002/cbf.3752
  58. www.sciencedirect.com www.sciencedirect.com
    Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites
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    sciencedirect.com/science/article/pii/S0092867422011230
  59. www.sciencedirect.com www.sciencedirect.com
    Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination
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    sciencedirect.com/science/article/pii/S2211124722012505
  60. Sep 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impairment of Neuronal Mitochondrial Quality Control in Prion-Induced Neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9454542/
  62. Jul 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activated Endolysosomal Cation Channel TRPML1 Facilitates Maturation of α-Synuclein-Containing Autophagosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9296810/
  64. Mar 2022
  65. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    sciencedirect.com/science/article/pii/S2211124722000705
  66. Feb 2022
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tri-2-Hydroxyarachidonein Induces Cytocidal Autophagy in Pancreatic Ductal Adenocarcinoma Cancer Cell Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC8811354/
  68. Jan 2022
  69. www.sciencedirect.com www.sciencedirect.com
    miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
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    sciencedirect.com/science/article/pii/S258900422200027X
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
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    ncbi.nlm.nih.gov/pmc/articles/PMC8773829/
  71. link.springer.com link.springer.com
    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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    link.springer.com/protocol/10.1007/978-1-0716-2071-7_10
  72. Nov 2021
  73. www.sciencedirect.com www.sciencedirect.com
    ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
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    sciencedirect.com/science/article/pii/S1534580721008078
  74. Oct 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
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    sciencedirect.com/science/article/pii/S0304416521001768
  76. Sep 2021
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Antitumor Compound HCA Promotes Glioma Cell Death by Inducing Endoplasmic Reticulum Stress and Autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8428344/
  78. Jun 2021
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8199856/
  80. www.sciencedirect.com www.sciencedirect.com
    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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    sciencedirect.com/science/article/pii/S2211124721005635
  81. www.nature.com www.nature.com
    The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2
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    nature.com/articles/s41467-021-23408-1
  82. May 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity
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    sciencedirect.com/science/article/pii/S1534580720308005
  84. Apr 2021
  85. www.sciencedirect.com www.sciencedirect.com
    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
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    sciencedirect.com/science/article/pii/S1534580721003075
  86. www.nature.com www.nature.com
    The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD
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    nature.com/articles/s41419-021-03620-z
  87. Feb 2021
  88. www.sciencedirect.com www.sciencedirect.com
    ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation
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    sciencedirect.com/science/article/pii/S1534580720310169
  89. Oct 2020
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556871/
  91. Sep 2020
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Ca2+ Uptake Relieves Palmitate-Induced Cytosolic Ca2+ Overload in MIN6 Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6999716/