103 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy
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    sciencedirect.com/science/article/pii/S0092867425009109
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The tandem CD33-CLL1 CAR-T as an approach to treat acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12274197/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Influenza A virus induces PI4P production at the endoplasmic reticulum in an ATG16L1-dependent manner to promote the egress of viral ribonucleoproteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12286409/
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    Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells
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    sciencedirect.com/science/article/pii/S1074761325003176
  6. Jul 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    African strains of Zika virus resist ISG-mediated restriction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12270304/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12198385/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR GENome and epigenome engineering improves loss-of-function genetic-screening approaches
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    pmc.ncbi.nlm.nih.gov/articles/PMC12272254/
  10. Jun 2025
  11. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70097
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    Comprehensive immune ageing reveals TREM2/TIM3 myeloid cells drive brain immune evasion
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    sciencedirect.com/science/article/pii/S2352396425002774
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thermostable lamprey variable lymphocyte receptor antibody for detection of Plasmodium falciparum histidine rich protein-2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12085579/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphoproteomics Reveals L1CAM-Associated Signaling Networks in High-Grade Serous Ovarian Carcinoma: Implications for Radioresistance and Tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12111665/
  15. link.springer.com link.springer.com
    Application of CRISPR-Based Epigenome Editing Tools for Engineering Programmable Embryo Models
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    link.springer.com/protocol/10.1007/7651_2025_637
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12165081/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11184310/
  18. May 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045047/
  20. Apr 2025
  21. www.biorxiv.org www.biorxiv.org
    TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia
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    biorxiv.org/content/10.1101/2025.04.07.647605v1
  22. 52.53.155.43 52.53.155.43
    PDF-html.html
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  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of FLYWCH1 as a regulator of platinum-resistance in epithelial ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11970373/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MITD1 is a brain-specific interferon-inducible factor that inhibits flavivirus replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962514/
  25. www.sciencedirect.com www.sciencedirect.com
    MicroRNA mechanisms instructing Purkinje cell specification
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    sciencedirect.com/science/article/pii/S0896627325001813
  26. www.biorxiv.org www.biorxiv.org
    Mechanosensitive interactions between Jag1 and Myo1c control Jag1 trafficking in endothelial cells
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    biorxiv.org/content/10.1101/2025.03.27.645426v1
  27. Mar 2025
  28. www.biorxiv.org www.biorxiv.org
    17q21.31 locus regulates Parkinson’s disease relevant pathways through KANSL1 activity
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    biorxiv.org/content/10.1101/2025.03.17.641409v1
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FoxO3 controls cardiomyocyte proliferation and heart regeneration by regulating Sfrp2 expression in postnatal mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11909131/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kallikrein-8 mediates furin-independent Activin-A precursor processing to stimulate tumor growth in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11893775/
  31. www.cell.com www.cell.com
    Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming
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    cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9
  32. Feb 2025
  33. aacrjournals.org aacrjournals.org
    Hyperthermic intrathoracic chemotherapy modulates the immune microenvironment of pleural mesothelioma and improves the impact of dual immune checkpoint inhibition
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    aacrjournals.org/cancerimmunolres/article/13/2/185/751253/Hyperthermic-Intrathoracic-Chemotherapy-Modulates
  34. Dec 2024
  35. www.sciencedirect.com www.sciencedirect.com
    YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
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    sciencedirect.com/science/article/pii/S0092867424013242
  36. Sep 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Breast Cancer Stem Cells Upregulate IRF6 in Stromal Fibroblasts to Induce Stromagenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393902/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383530/
  39. Aug 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetically modified human embryonic stem cell-derived otic neurons establish functional synaptic connection with cochlear nuclei
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292720/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295348/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11305397/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD177 is a novel IgG Fc receptor and CD177 genetic variants affect IgG-mediated function
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316256/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830842/
  46. Jul 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Helicobacter pylori-Induced Decrease in Membrane Expression of Na,K-ATPase Leads to Gastric Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC11274427/
  48. www.sciencedirect.com www.sciencedirect.com
    Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
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    sciencedirect.com/science/article/pii/S2667237524001838
  49. www.embopress.org www.embopress.org
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    embopress.org/doi/10.1038/s44318-024-00164-8
  50. Jun 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11208438/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of human U5 snRNP late biogenesis and recycling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7616108/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145263/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking
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    ncbi.nlm.nih.gov/pmc/articles/PMC11135703/
  55. May 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11111795/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090050/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engagement of sialylated glycans with Siglec receptors on suppressive myeloid cells inhibits anticancer immunity via CCL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061307/
  59. Apr 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/dCas9-Tet1-Mediated DNA Methylation Editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056002/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Remodeling in Patient‐Derived Colorectal Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11040356/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014252/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966137/
  64. Mar 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959073/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted protein degradation via intramolecular bivalent glues
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    ncbi.nlm.nih.gov/pmc/articles/PMC10917667/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RhoU forms homo-oligomers to regulate cellular responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10917059/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation regulates viral biomolecular condensates to promote infectious progeny production
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897327/
  69. Feb 2024
  70. www.biorxiv.org www.biorxiv.org
    A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence
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    biorxiv.org/content/10.1101/2024.02.09.579635v1
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus lytic gene BNRF1 promotes B-cell lymphomagenesis via IFI27 upregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10833513/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10824881/
  73. Jan 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 overexpression in ovarian tumors remodels the tumor microenvironment and increases T-cell reactivity toward autologous tumor-associated antigens
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    ncbi.nlm.nih.gov/pmc/articles/PMC10791902/
  75. www.sciencedirect.com www.sciencedirect.com
    Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3
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    sciencedirect.com/science/article/pii/S2352396423005194
  76. Dec 2023
  77. www.nature.com www.nature.com
    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    nature.com/articles/s41467-023-43657-6
  78. Nov 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  80. www.sciencedirect.com www.sciencedirect.com
    Developmental potency of human ES cell-derived mesenchymal stem cells revealed in mouse embryos following blastocyst injection
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    sciencedirect.com/science/article/pii/S2211124723014717
  81. www.nature.com www.nature.com
    Engineering a scalable and orthogonal platform for synthetic communication in mammalian cells
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    nature.com/articles/s41467-023-42810-5
  82. Sep 2023
  83. www.nature.com www.nature.com
    MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression
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    nature.com/articles/s41698-023-00437-1
  84. link.springer.com link.springer.com
    The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
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    link.springer.com/article/10.1007/s11481-023-10082-x
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
  86. Aug 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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    sciencedirect.com/science/article/pii/S1097276523005671
  88. www.biorxiv.org www.biorxiv.org
    The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming
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    biorxiv.org/content/10.1101/2023.07.31.551297v3
  89. May 2023
  90. www.biorxiv.org www.biorxiv.org
    Single-cycle SARS-CoV-2 vaccine elicits high protection and sterilizing immunity in hamsters
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    biorxiv.org/content/10.1101/2023.05.17.541127v1
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC10163034/
  92. www.sciencedirect.com www.sciencedirect.com
    Production and characterization of lentivirus vector-based SARS-CoV-2 pseudoviruses with dual reporters: Evaluation of anti-SARS-CoV-2 viral effect of Korean red ginseng
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    sciencedirect.com/science/article/pii/S1226845322000902
  93. Mar 2023
  94. 52.53.155.43 52.53.155.43
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  95. www.biorxiv.org www.biorxiv.org
    The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex
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    biorxiv.org/content/10.1101/2023.02.03.526966v1
  96. Feb 2023
  97. www.sciencedirect.com www.sciencedirect.com
    Archaic humans have contributed to large-scale variation in modern human T cell receptor genes
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    sciencedirect.com/science/article/pii/S1074761323000389
  98. www.sciencedirect.com www.sciencedirect.com
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
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    sciencedirect.com/science/article/pii/S1097276523000382
  99. Jan 2023
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9716251/
  101. www.sciencedirect.com www.sciencedirect.com
    Ribosomal RNA-based epitranscriptomic regulation of chondrocyte translation and proteome in osteoarthritis
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    sciencedirect.com/science/article/pii/S1063458423000018
  102. Dec 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9770512/
  104. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    link.springer.com/article/10.1007/s12035-022-03153-2
  105. aacrjournals.org aacrjournals.org
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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    aacrjournals.org/cancerrescommun/article/2/12/1545/711358/IL1-Expression-Driven-by-Androgen-Receptor-Absence
  106. Nov 2022
  107. academic.oup.com academic.oup.com
    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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    academic.oup.com/brain/advance-article/doi/10.1093/brain/awac325/6694190
  108. Oct 2022
  109. www.nature.com www.nature.com
    The coilin N-terminus mediates multivalent interactions between coilin and Nopp140 to form and maintain Cajal bodies
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    nature.com/articles/s41467-022-33434-2
  110. Aug 2022
  111. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    sciencedirect.com/science/article/pii/S2211124722009949
  112. Jun 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering of human mesenchymal stem cells resistant to multiple natural killer subtypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC8692142/
  114. May 2022
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development
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    ncbi.nlm.nih.gov/pmc/articles/PMC9045715/
  116. www.science.org www.science.org
    The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development
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    science.org/doi/full/10.1126/sciadv.abm7012
  117. Apr 2022
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    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
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  119. Jan 2022
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    p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function
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  121. Aug 2021
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    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
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  124. Jul 2021
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  126. Jun 2021
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    DMA-tudor interaction modules control the specificity of in vivo condensates
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  128. May 2021
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    Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation
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  130. Feb 2021
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    Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro
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  132. Dec 2020
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    Structure of the human core transcription-export complex reveals a hub for multivalent interactions
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  134. Oct 2020
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    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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  136. Sep 2020
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    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
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    Synapse elimination activates a coordinated homeostatic presynaptic response in an autaptic circuit
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    CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
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    FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth
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  141. Jan 2020
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    Outside‐in regulation of the readily releasable pool of synaptic vesicles by α2δ‐1
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