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Saturating variant analysis of TERC redefines the human telomerase reverse transcription mechanism

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1. scibot 09 Oct 2026
  
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  26655
  
  DOI: 10.64898/2026.06.01.728939
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13252387/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SIRT7 Inhibits Adipose Tissue Browning Through Deacetylation of PPARγ2 at K382

1
1. scibot 09 Oct 2026
  
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  26655
  
  DOI: 10.3390/cells15111028
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13256863/
Oct 2026
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MTAP loss upregulates BCAT1 in pancreatic cancer and drives branched-chain amino acid dependency

1
1. scibot 01 Oct 2026
  
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  AddgeneCat#26655
  
  DOI: 10.1016/j.celrep.2026.118046
  
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sciencedirect.com/science/article/pii/S2211124726011241
Sep 2026
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Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene expression

1
1. scibot 18 Sep 2026
  
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  Addgene_26655
  
  DOI: 10.1016/j.molcel.2026.08.022
  
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sciencedirect.com/science/article/pii/S1097276526005915
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SCP4 dephosphorylates mitotic histone H3 to maintain chromosome stability

1
1. scibot 08 Aug 2026
  
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  pLKO.1-Blasticidin
  
  DOI: 10.1038/s44319-026-00833-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13400628/
Jul 2026
aacrjournals.org aacrjournals.org

FOSL1 Orchestrates Epigenetic Reprogramming of Anaplastic Thyroid Cancer and Suppresses Natural Killer Cell-Mediated Antitumor Immunity

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1. scibot 12 Jul 2026
  
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  RRID:Addgene_26655
  
  DOI: 10.1158/0008-5472.CAN-25-2781
  
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aacrjournals.org/cancerres/article/86/9/2184/784010/FOSL1-Orchestrates-Epigenetic-Reprogramming-of
Mar 2026
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Microhomology-mediated end joining acts directly on replication forks to repair single-ended double-strand breaks

1
1. scibot 17 Mar 2026
  
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  RRID:Addgene_26655
  
  DOI: 10.1016/j.molcel.2026.02.016
  
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sciencedirect.com/science/article/pii/S1097276526001309
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Chromobox2 inhibition: a novel activity of alisertib, an aurora A kinase inhibitor

1
1. scibot 07 Feb 2026
  
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  RRID:Addgene_26655
  
  DOI: 10.1158/1535-7163.MCT-25-0279
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12866977/
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nucleosome stability safeguards cell identity, stress resilience and healthy aging

1
1. scibot 31 Dec 2025
  
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  addgene_26655
  
  DOI: 10.21203/rs.3.rs-7913970/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12668177/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA

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1. scibot 04 Dec 2025
  
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  Addgene_26655
  
  DOI: 10.1016/j.molcel.2025.11.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12709618/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hypoxia increases susceptibility of human intestinal epithelial cells to rotavirus infection through repression of interferon induction

1
1. scibot 23 Nov 2025
  
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  26,655
  
  DOI: 10.1080/19490976.2025.2560593
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12456215/
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CHD7 binds to insulators during neuronal differentiation

1
1. scibot 23 Nov 2025
  
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  Addgene_26655
  
  DOI: 10.1101/2025.03.28.646031
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11974851/
Sep 2025
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Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

1
1. scibot 25 Sep 2025
  
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  AddgeneCat# 26655
  
  DOI: 10.1016/j.celrep.2025.116185
  
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sciencedirect.com/science/article/pii/S2211124725009568
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nucleosome stability safeguards cell identity, stress resilience and healthy aging

1
1. scibot 23 Sep 2025
  
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  addgene_26655
  
  DOI: 10.1101/2025.09.17.676776
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12458469/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome

1
1. scibot 11 Aug 2025
  
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  26655
  
  DOI: 10.1126/sciimmunol.adn8715
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12291065/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination

1
1. scibot 20 Jul 2025
  
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  26655
  
  DOI: 10.1093/nar/gkaf554
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12231572/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DNA methylation protects cancer cells against senescence

1
1. scibot 20 Jul 2025
  
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  Addgene_26655
  
  DOI: 10.1038/s41467-025-61157-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12216915/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma

1
1. scibot 17 May 2025
  
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  26655
  
  DOI: 10.1158/2159-8290.CD-24-1317
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046326/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate

1
1. scibot 17 May 2025
  
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  26655
  
  DOI: 10.1101/gad.352316.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12047658/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EIF3D safeguards the homeostasis of key signaling pathways in human primed pluripotency

1
1. scibot 16 May 2025
  
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  26655
  
  DOI: 10.1126/sciadv.adq5484
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980838/
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HSP90 regulates dCK stability and inhibits ionizing radiation-induced ferroptosis in cervical cancer cells

1
1. scibot 16 May 2025
  
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  pLKO.1-blasticidin
  
  DOI: 10.1038/s41420-025-02388-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12015294/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response

1
1. scibot 29 Mar 2025
  
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  Addgene.orgCat# 26655
  
  DOI: 10.1016/j.celrep.2025.115434
  
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sciencedirect.com/science/article/pii/S2211124725002050
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AdipoR1 enhances the radiation resistance via ESR1/CCNB1IP1/cyclin B1 pathway in hepatocellular carcinoma cells

1
1. scibot 27 Jan 2025
  
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  pLKO. 1-blasticidin
  
  DOI: 10.1186/s10020-025-01065-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11755959/
www.sciencedirect.com www.sciencedirect.com

DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

1
1. scibot 09 Jan 2025
  
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  AddgeneCat#26655
  
  DOI: 10.1016/j.celrep.2024.115174
  
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sciencedirect.com/science/article/pii/S2211124724015250
52.53.155.43 52.53.155.43

1-s2.0-S2589004224029377-main-html.html

1
1. scibot 03 Jan 2025
  
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  plasmid # 26655
  
  DOI: 10.1016/j.isci.2024.111710
  
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  Curator: @inessasarian
  
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52.53.155.43/a4a95d0f48e4f5d6b60e2092f92dc9e622c6d3c5/1-s2.0-S2589004224029377-main-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor

1
1. scibot 10 Dec 2024
  
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  RRID:Addgene_26655
  
  DOI: 10.1016/j.cell.2024.11.009
  
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sciencedirect.com/science/article/pii/S0092867424013266
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Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms

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1. scibot 02 Dec 2024
  
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  AddgeneCat#26655
  
  DOI: 10.1016/j.immuni.2024.10.015
  
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  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S1074761324004941
Nov 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Targeting ATAD3A Phosphorylation Mediated by TBK1 Ameliorates Senescence-Associated Pathologies

1
1. scibot 15 Nov 2024
  
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  RRID:Addgene_26655
  
  DOI: 10.1002/advs.202404109
  
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202404109
Sep 2024
www.biorxiv.org www.biorxiv.org

Nuclear body reorganization by the viral RNA kaposin promotes Kaposi’s sarcoma-associated herpesvirus gene expression

1
1. scibot 27 Sep 2024
  
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  RRID:Addgene_26655
  
  DOI: 10.1101/2024.09.20.614208
  
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biorxiv.org/content/10.1101/2024.09.20.614208v1
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ELM2‐SANT Domain‐Containing Scaffolding Protein 1 Regulates Differentiation and Maturation of Cardiomyocytes Derived From Human‐Induced Pluripotent Stem Cells

1
1. scibot 26 Aug 2024
  
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  Addgene_26655
  
  DOI: 10.1161/JAHA.124.034816
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11255699/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis

1
1. scibot 23 Apr 2024
  
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  Addgene, 26655
  
  DOI: 10.1016/j.cell.2024.03.030
  
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  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S0092867424003465
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

1
1. scibot 13 Apr 2024
  
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  Addgene_26655
  
  DOI: 10.1038/s41467-024-47314-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10997609/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis

1
1. scibot 21 Feb 2024
  
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  26655
  
  DOI: 10.1038/s41467-024-45585-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10867109/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker

1
1. scibot 13 Feb 2024
  
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  pLKO.1-blast
  
  DOI: 10.1016/j.tranon.2024.101882
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844751/
Sep 2023
dx.doi.org dx.doi.org

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

1
1. scibot 22 Sep 2023
  
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  Addgene_26655
  
  DOI: 10.1093/nar/gkad733
  
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dx.doi.org/10.1093/nar/gkad733
Jun 2023
www.sciencedirect.com www.sciencedirect.com

KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2

1
1. scibot 02 Jun 2023
  
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  Plasmid #26655
  
  DOI: 10.1016/j.isci.2023.106914
  
  Resource: RRID:Addgene_26655
  
  Curator: @sofiakhan13
  
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sciencedirect.com/science/article/pii/S2589004223009914
Mar 2023
academic.oup.com academic.oup.com

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

1
1. scibot 23 Mar 2023
  
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  Addgene_26655
  
  DOI: 10.1093/nar/gkad172
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad172/7079642
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies

1
1. scibot 28 Jan 2023
  
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  RRID:Addgene_26655
  
  DOI: 10.1371/journal.ppat.1011080
  
  Resource: RRID:Addgene_26655
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9876383/
www.cell.com www.cell.com

Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation

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1. scibot 06 Jan 2023
  
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  Addgene_26655
  
  DOI: 10.1016/j.cell.2022.12.004
  
  Resource: RRID:Addgene_26655
  
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cell.com/cell/fulltext/S0092-8674(22)01517-3
Dec 2022
journals.plos.org journals.plos.org

A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells

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1. scibot 05 Dec 2022
  
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  Addgene_26655
  
  DOI: 10.1371/journal.pbio.3001885
  
  Resource: RRID:Addgene_26655
  
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journals.plos.org/plosbiology/article
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing

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1. scibot 16 Feb 2022
  
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  Addgene26655
  
  DOI: 10.1016/j.celrep.2022.110357
  
  Resource: RRID:Addgene_26655
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S2211124722000766
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 29 Jul 2021
  
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  Addgene26655
  
  DOI: 10.1016/j.ccell.2019.08.006
  
  Resource: RRID:Addgene_26655
  
  Curator: @ethanbadger
  
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  RRID:Addgene_26655 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1535610819303745
Jun 2021
www.sciencedirect.com www.sciencedirect.com

NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

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1. scibot 17 Jun 2021
  
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  26655
  
  DOI: 10.1016/j.celrep.2021.109238
  
  Resource: RRID:Addgene_26655
  
  Curator: @Naa003
  
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  RRID:Addgene_26655 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721005970
Mar 2021
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner

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1. scibot 03 Mar 2021
  
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  RRID:Addgene_26655
  
  DOI: 10.1096/fj.202001909R
  
  Resource: RRID:Addgene_26655
  
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  RRID:Addgene_26655 RRIDCUR:Validated
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001909R
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

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1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_26655
  
  DOI: 10.1016/j.ccell.2019.01.018
  
  Resource: RRID:Addgene_26655
  
  Curator: @ethanbadger
  
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  RRID:Addgene_26655 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300522