153 Matching Annotations
  1. Last 7 days
  2. www.nature.com www.nature.com
    Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells
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    nature.com/articles/s41589-025-02113-w
  3. Jan 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kallikrein 14 activates the chemoattractant protein chemerin in human skin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12796741/
  5. Dec 2025
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Assessing Angiogenic Properties In Vitro or In Ovo of Pre-Crosslinked Alginate-Dialdehyde-Gelatin Hydrogels Incorporating Boron-Doped Mesoporous Bioactive Glass Particles
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    advanced.onlinelibrary.wiley.com/doi/10.1002/anbr.202500143
  7. Nov 2025
  8. 54.241.53.176 54.241.53.176
    thayer-et-al-2025-a-unified-mechanism-for-mitochondrial-damage-sensing-in-pink1-parkin-mediated-mitophagy-html.html
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    54.241.53.176/efd02b1a93da439b26b6ec3b31fa86116874758b/thayer-et-al-2025-a-unified-mechanism-for-mitochondrial-damage-sensing-in-pink1-parkin-mediated-mitophagy-html.html
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATOH8 is crucial for the differentiation of human trophoblast stem cells into extravillous trophoblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586484/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for hybrid mass spectrometry-AI mapping of proteasome-generated HLA class I epitopes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12590422/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNA2 enables growth by restricting recombination-restarted replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12545200/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Synthetic Sponge System Against miRNAs of the miR-17/92 Cluster Targets Transcriptional MYC Dosage Compensation in Aneuploid Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12427730/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inducible tag-free degradation of endogenous proteins with AlissAID and development of a photoactivable inducer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603123/
  14. Oct 2025
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Arid1a Deficiency Drives Aristolochic Acid-Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513981
  16. www.biorxiv.org www.biorxiv.org
    Red-light-only control of protein-protein interactions using a cyanobacteriochrome (UNICYCL)
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    biorxiv.org/content/10.1101/2025.10.09.681461v1
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12515706/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509757/
  19. www.sciencedirect.com www.sciencedirect.com
    Phocaeicola vulgatus induces immunotherapy resistance in hepatocellular carcinoma via reducing indoleacetic acid production
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    sciencedirect.com/science/article/pii/S2666379125004434
  20. Sep 2025
  21. www.science.org www.science.org
    Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome
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    science.org/doi/10.1126/sciadv.adw2539
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12442851/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual targeting of solid tumors using cytokine-induced killer cells modified with a CAR anti-tenascin C and a secretable EGFRxCD3 bispecific antibody
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    pmc.ncbi.nlm.nih.gov/articles/PMC12433391/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12365544/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GCDH Acetylation Orchestrates DNA Damage Response and Autophagy via Mitochondrial ROS to Suppress Hepatocellular Carcinoma Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12395558/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12391391/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conversion of natural cytokine receptors into orthogonal synthetic biosensors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380174/
  28. Aug 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12274589/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resolving native GABAA receptor structures from the human brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12103249/
  31. www.sciencedirect.com www.sciencedirect.com
    Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
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    sciencedirect.com/science/article/pii/S1097276525006070
  32. www.sciencedirect.com www.sciencedirect.com
    Computational framework for prioritizing candidate compounds overcoming the resistance of pancancer immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003490
  33. www.sciencedirect.com www.sciencedirect.com
    Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase
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    sciencedirect.com/science/article/pii/S2589004225013926
  34. Jul 2025
  35. www.sciencedirect.com www.sciencedirect.com
    Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy
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    sciencedirect.com/science/article/pii/S0092867425007937
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of oligodendrocyte enhancers that regulate Sox10 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12266436/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233092/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1/NANS in c-Myc-Driven Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12269569/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12259638/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serotonin receptor 5-HT2A as a potential target for HCC immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186046/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD81 is a receptor for equine arteritis virus (family: Arteriviridae)
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  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HP1 loses its chromatin clustering and phase separation function across evolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC12246093/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of a spontaneous murine HPV + oral cancer model with site-specific oncogene insertion using CRISPR-SONIC
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    pmc.ncbi.nlm.nih.gov/articles/PMC12175459/
  44. www.biorxiv.org www.biorxiv.org
    ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts
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    biorxiv.org/content/10.1101/2025.06.12.659268v1
  45. Jun 2025
  46. journals.sagepub.com journals.sagepub.com
    A homozygous single-nucleotide variant in TNNT1 causes abnormal troponin T isoform expression in a patient with severe nemaline myopathy: A case report
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    journals.sagepub.com/doi/full/10.1177/22143602251339569
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12119886/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision multiplexed base editing in human cells using Cas12a-derived base editors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126522/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induced Neural Progenitor Specification from Human Pluripotent Stem Cells by a Refined Synthetic Notch Platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12090341/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148440/
  51. May 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The bacterial type three secretion system induces mechanoporation of vacuolar membranes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045489/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting adenine base editing efficiencies in different cellular contexts by deep learning
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  54. 52.53.155.43 52.53.155.43
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  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Attenuating ABHD17 Isoforms Augments the S-acylation and Function of NOD2 and a Subset of Crohn’s Disease-associated NOD2 Variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005342/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VDAC2 loss elicits tumour destruction and inflammation for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12018455/
  57. Apr 2025
  58. aacrjournals.org aacrjournals.org
    METTL3-mediated m6A modification regulates the polycomb repressive complex 1 (PRC1) components BMI1 and RNF2 in hepatocellular carcinoma cells
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    aacrjournals.org/mcr/article/23/3/190/752031/METTL3-Mediated-m6A-Modification-Regulates-the
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Influenza virus antagonizes self sensing by RIG-I to enhance viral replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952396/
  60. Mar 2025
  61. www.sciencedirect.com www.sciencedirect.com
    Nuclear exclusion of condensin I in prophase coordinates mitotic chromosome reorganization to ensure complete sister chromatid resolution
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    sciencedirect.com/science/article/pii/S0960982225002118
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769251/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870511/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling enhanced liver regeneration in ALPPS: Integrating multi-omics profiling and in vivo CRISPR in mouse models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888979/
  65. www.cell.com www.cell.com
    Generation and GMP scale-up of human CAR-T cells using non-viral Sleeping Beauty transposons for B cell malignances
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    cell.com/molecular-therapy-family/advances/fulltext/S2329-0501(25)00020-8
  66. Feb 2025
  67. www.sciencedirect.com www.sciencedirect.com
    Mutational pressure promotes release of public CD8+ T cell epitopes by proteasome from SARS-CoV-2 RBD of Omicron and its current lineages
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    sciencedirect.com/science/article/pii/S2589004225001336
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High throughput analysis of rare nanoparticles with deep-enhanced sensitivity via unsupervised denoising
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842628/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Live-Cell Imaging-Based Fluorescent SARS-CoV-2 Neutralization Assay by Antibody-Mediated Blockage of Receptor Binding Domain-ACE2 Interaction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11843899/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Using the Sleeping Beauty Transposon System for Doxycycline-inducible Gene Expression in RAW264.7 Macrophage Cells to Study Phagocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11825295/
  71. aacrjournals.org aacrjournals.org
    Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
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    aacrjournals.org/cancerdiscovery/article/12/7/1718/705192/IFN-Potentiates-Anti-PD-1-Efficacy-by-Remodeling
  72. 52.53.155.43 52.53.155.43
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  73. Jan 2025
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination
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  75. Dec 2024
  76. 52.53.155.43 52.53.155.43
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  77. Nov 2024
  78. 52.53.155.43 52.53.155.43
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    PPM1G Inhibits Epithelial–Mesenchymal Transition in Cholangiocarcinoma by Catalyzing TET1 Dephosphorylation for Destabilization to Impair Its Targeted Demethylation of the CLDN3 Promoter
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    onlinelibrary.wiley.com/doi/10.1002/advs.202407323
  80. Sep 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Tracking and 3D Mapping of Cell Death in Regeneration and Cancer Using Trypan Blue
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352400/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDX1 downregulation activates mitophagy and the PI3K/AKT signaling pathway to promote hepatocellular carcinoma progression by inducing ROS production
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366913/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STUB1-mediated K63-linked ubiquitination of UHRF1 promotes the progression of cholangiocarcinoma by maintaining DNA hypermethylation of PLA2G2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC11395162/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Activity of Cytokine-Induced Killer Cells Enhanced by CAR-CD19 Modification or by Soluble Bispecific Antibody Blinatumomab
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    ncbi.nlm.nih.gov/pmc/articles/PMC11417890/
  86. Aug 2024
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of BCL-XL overcomes venetoclax resistance across BCL2+ lymphoid malignancies irrespective of BIM status
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261020/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oleic acid released by sensory neurons inhibits TRPV1-mediated thermal hypersensitivity via GPR40
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    ncbi.nlm.nih.gov/pmc/articles/PMC11338150/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo interaction screening reveals liver-derived constraints to metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306111/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinesins regulate the heterogeneity in centrosome clustering after whole-genome duplication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11287020/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD4 R975H mutant activates tumorigenic pathways and promotes stemness and M2-like macrophage polarization in endometrial cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316823/
  93. Jul 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The molecular basis of tRNA selectivity by human pseudouridine synthase 3
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    ncbi.nlm.nih.gov/pmc/articles/PMC11258540/
  95. Jun 2024
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mobilization and activation of tumor-infiltrating dendritic cells inhibits lymph node metastasis in intrahepatic cholangiocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11208581/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189632/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic loss of GPR108 disrupts AAV transduction in birds
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    ncbi.nlm.nih.gov/pmc/articles/PMC11118497/
  99. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
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    sciencedirect.com/science/article/pii/S0092867424005208
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11138074/
  101. May 2024
  102. www.biorxiv.org www.biorxiv.org
    Conversion of natural cytokine receptors into orthogonal synthetic biosensors
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  106. Apr 2024
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  110. Mar 2024
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  115. Feb 2024
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  124. Sep 2023
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  128. Aug 2023
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  130. Jun 2023
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  133. May 2023
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  139. Apr 2023
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  142. Mar 2023
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  145. Feb 2023
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  148. Jan 2023
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  153. Nov 2022
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    Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line
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  155. Oct 2022
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  158. Aug 2022
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  160. Jul 2022
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  162. Jun 2022
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  166. Feb 2022
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    In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
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  169. Dec 2021
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  173. Nov 2021
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  175. Oct 2021
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  177. Sep 2021
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    Drebrin Regulates Acetylcholine Receptor Clustering and Organization of Microtubules at the Postsynaptic Machinery
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  179. Aug 2021
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    Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology
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  181. Jul 2021
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  183. Jun 2021
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  185. May 2021
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    Missense mutations in small muscle protein X-linked ( SMPX ) cause distal myopathy with protein inclusions
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  187. Apr 2021
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    Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells
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    TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
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  191. Mar 2021
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  193. Feb 2021
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    Functional Evaluation of a Rare Variant c.516G>C (p.Trp172Cys) in the GJB2 (Connexin 26) Gene Associated with Nonsyndromic Hearing Loss
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  195. Jan 2021
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  197. Sep 2020
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    Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
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  201. Jan 2020
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