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www.sciencedirect.com:5037 www.sciencedirect.com:5037

Linked-domain inhibitors designed to block UBE2D induce the unfolded protein response

1
1. scibot 09 Dec 2025
  
  in Public
  
  Addgenecat#34965
  
  DOI: 10.1016/j.chembiol.2025.11.007
  
  Resource: RRID:Addgene_34965
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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RRID:Addgene_34965

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scibot

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sciencedirect.com:5037/science/article/pii/S2451945625003770
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4

1
1. scibot 15 Jun 2025
  
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  34965
  
  DOI: 10.1038/s42004-025-01557-4
  
  Resource: RRID:Addgene_34965
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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pmc.ncbi.nlm.nih.gov/articles/PMC12119865/
Mar 2025
elifesciences.org elifesciences.org

Elucidating the Mechanism Underlying UBA7•UBE2L6 Disulfide Complex Formation

1
1. scibot 13 Mar 2025
  
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  34965
  
  DOI: 10.7554/eLife.105638.1
  
  Resource: RRID:Addgene_34965
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965 DOI:10.7554/eLife.105638.1
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DOI:10.7554/eLife.105638.1

RRID:Addgene_34965

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elifesciences.org/reviewed-preprints/105638
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature

1
1. scibot 05 Dec 2024
  
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  RRID:Addgene_34965
  
  DOI: 10.1038/s44318-024-00268-1
  
  Resource: RRID:Addgene_34965
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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pmc.ncbi.nlm.nih.gov/articles/PMC11612235/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans

1
1. scibot 29 Sep 2024
  
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  34965
  
  DOI: 10.7554/eLife.96699
  
  Resource: RRID:Addgene_34965
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965 DOI:10.7554/eLife.96699
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DOI:10.7554/eLife.96699

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ncbi.nlm.nih.gov/pmc/articles/PMC11368401/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates

1
1. scibot 14 Apr 2024
  
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  34965
  
  DOI: 10.1126/sciadv.add4253
  
  Resource: RRID:Addgene_34965
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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RRID:Addgene_34965

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ncbi.nlm.nih.gov/pmc/articles/PMC7615817/
May 2023
www.biorxiv.org www.biorxiv.org

Discovery of DTX3L inhibitors through a homogeneous FRET-based assay that monitors formation and removal of poly-ubiquitin chains

1
1. scibot 04 May 2023
  
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  RRID:Addgene_34965
  
  DOI: 10.1101/2023.03.13.532453
  
  Resource: RRID:Addgene_34965
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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RRID:Addgene_34965

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biorxiv.org/content/10.1101/2023.03.13.532453v1
Feb 2021
portlandpress.com portlandpress.com

Herpes simplex virus 1 infection induces ubiquitination of UBE1a

1
1. scibot 28 Feb 2021
  
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  RRID:Addgene_34965
  
  DOI: 10.1042/BCJ20200885
  
  Resource: RRID:Addgene_34965
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965
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portlandpress.com/biochemj/article/478/1/261/227419/Herpes-simplex-virus-1-infection-induces
www.mdpi.com www.mdpi.com

UBE1a Suppresses Herpes Simplex Virus-1 Replication

1
1. scibot 24 Feb 2021
  
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  plasmid_34
  
  DOI: 10.3390/v12121391
  
  Resource: RRID:Addgene_34965
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_34965
  
  Curator comments: Ube1/PET21d
  
  What is this?
  
  RRID:Addgene_34965 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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RRID:Addgene_34965

RRIDCUR:SyntaxError

RRIDCUR:Unresolved

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scibot

URL

mdpi.com/1999-4915/12/12/1391
Dec 2020
www.mdpi.com www.mdpi.com

UBE1a Suppresses Herpes Simplex Virus-1 Replication

1
1. scibot 11 Dec 2020
  
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  RRID:Addgene_34965
  
  DOI: 10.3390/v12121391
  
  Resource: RRID:Addgene_34965
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_34965
  
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  RRID:Addgene_34965 RRIDCUR:Validated
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RRID:Addgene_34965

RRIDCUR:Validated

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scibot

URL

mdpi.com/1999-4915/12/12/1391