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www.sciencedirect.com:5037 www.sciencedirect.com:5037

Fibrillarin regulates epithelial integrity via EZH2-mediated modulation of scribble expression

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1. scibot 29 Nov 2025
  
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  Addgene_35614
  
  DOI: 10.1016/j.celrep.2025.116608
  
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sciencedirect.com:5037/science/article/pii/S2211124725013804
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration

1
1. scibot 24 Nov 2025
  
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  35614
  
  DOI: 10.1186/s13059-025-03774-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12509411/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment

1
1. scibot 23 Nov 2025
  
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  35614
  
  DOI: 10.1101/2025.03.24.645001
  
  Resource: RRID:Addgene_35614
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11974748/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment

1
1. scibot 23 Nov 2025
  
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  35614
  
  DOI: 10.1073/pnas.2511890122
  
  Resource: RRID:Addgene_35614
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12337332/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins

1
1. scibot 06 Sep 2025
  
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  35614
  
  DOI: 10.1038/s41467-025-63167-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12381050/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

1
1. scibot 17 May 2025
  
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  35614
  
  DOI: 10.1038/s41467-025-59377-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12041237/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting BCL11B in CAR-engineered lymphoid progenitors drives NK-like cell development with prolonged anti-leukemic activity

1
1. scibot 16 May 2025
  
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  pBS-CMV-gagpol
  
  DOI: 10.1016/j.ymthe.2025.02.024
  
  Resource: RRID:Addgene_35614
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11997514/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids

1
1. scibot 07 Apr 2025
  
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  plasmid_35614
  
  DOI: 10.1016/j.isci.2025.111979
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11938077/
Mar 2025
www.nature.com www.nature.com

Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations

1
1. scibot 11 Mar 2025
  
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  35614
  
  DOI: 10.1038/s41586-024-08533-3
  
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nature.com/articles/s41586-024-08533-3
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors

1
1. scibot 11 Mar 2025
  
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  35614
  
  DOI: 10.1038/s41586-024-08532-4
  
  Resource: RRID:Addgene_35614
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11882444/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair

1
1. scibot 11 Mar 2025
  
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  35614
  
  DOI: 10.1038/s41467-025-56085-5
  
  Resource: RRID:Addgene_35614
  
  Curator: @olekpark
  
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  DOI:10.1038/s41467-025-56085-5 RRID:Addgene_35614
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DOI:10.1038/s41467-025-56085-5

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pmc.ncbi.nlm.nih.gov/articles/PMC11762318/
Dec 2024
www.biorxiv.org www.biorxiv.org

Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography

1
1. scibot 03 Dec 2024
  
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  RRID:Addgene_35614
  
  DOI: 10.1101/2024.11.25.625301
  
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biorxiv.org/content/10.1101/2024.11.25.625301v1
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

1
1. scibot 28 Sep 2024
  
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  35614
  
  DOI: 10.21203/rs.3.rs-4810212/v1
  
  Resource: RRID:Addgene_35614
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11384819/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immunogen characterization reveals an intrinsic hindrance in eliciting neutralizing antibodies against JN.1 variant

1
1. scibot 26 Sep 2024
  
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  35614
  
  DOI: 10.1016/j.isci.2024.110405
  
  Resource: RRID:Addgene_35614
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11300904/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts

1
1. scibot 13 Apr 2024
  
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  RRID:Addgene_35614
  
  DOI: 10.1128/mbio.03278-23
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11005365/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics

1
1. scibot 07 Feb 2024
  
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  RRID:Addgene_35614
  
  DOI: 10.1016/j.crmeth.2024.100698
  
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sciencedirect.com/science/article/pii/S2667237524000043
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

1
1. scibot 29 Jan 2024
  
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  GAG-Pro-Pol (35614)
  
  DOI: 10.1101/2024.01.11.575257
  
  Resource: RRID:Addgene_35614
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802600/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts

1
1. scibot 20 Dec 2023
  
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  RRID:Addgene_35614
  
  DOI: 10.1101/2023.12.03.569766
  
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  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10705572/
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection

1
1. scibot 16 Jun 2023
  
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  plasmid_35614
  
  DOI: 10.1371/journal.ppat.1009831
  
  Resource: RRID:Addgene_35614
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8853520/
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication

1
1. scibot 22 Apr 2023
  
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  plasmid_35614
  
  DOI: 10.3389/fimmu.2018.00492
  
  Resource: RRID:Addgene_35614
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5869724/
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

1
1. scibot 12 Jan 2022
  
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  Addgene35614
  
  DOI: 10.1016/j.cell.2021.12.021
  
  Resource: RRID:Addgene_35614
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S0092867421014847