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www.sciencedirect.com www.sciencedirect.com

Skin-derived α-synuclein strains from PD, DLB, and MSA induce distinct intracellular pathology and neurodegeneration

1
1. scibot 09 Jan 2026
  
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  plasmid_40823
  
  DOI: 10.1016/j.jbc.2025.111005
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
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  RRID:Addgene_40823
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sciencedirect.com/science/article/pii/S0021925825028571
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo

1
1. scibot 22 Sep 2025
  
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  plasmid_40823
  
  DOI: 10.1126/sciadv.ady5212
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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pmc.ncbi.nlm.nih.gov/articles/PMC12442881/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrating artificial intelligence and optogenetics for Parkinson’s disease diagnosis and therapeutics in male mice

1
1. scibot 07 Sep 2025
  
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  Addgene_40823
  
  DOI: 10.1038/s41467-025-63025-w
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
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  RRID:Addgene_40823
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pmc.ncbi.nlm.nih.gov/articles/PMC12370958/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ANKZF1 helps to eliminate stress-damaged mitochondria by LC3-mediated mitophagy

1
1. scibot 11 Aug 2025
  
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  Addgene_40823
  
  DOI: 10.1038/s41420-025-02638-y
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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pmc.ncbi.nlm.nih.gov/articles/PMC12307761/
Mar 2025
www.biorxiv.org www.biorxiv.org

Mitochondria serve as a Holdout Compartment for Aggregation-Prone Proteins hindering Efficient Ubiquitin-Dependent Degradation

1
1. scibot 07 Mar 2025
  
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  Addgene #40823
  
  DOI: 10.1101/2025.02.27.640505
  
  Resource: RRID:Addgene_40823
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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biorxiv.org/content/10.1101/2025.02.27.640505v1
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The SATB1‐MIR22‐GBA axis mediates glucocerebroside accumulation inducing a cellular senescence‐like phenotype in dopaminergic neurons

2
1. scibot 19 Apr 2024
  
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  RRID:Addgene_40823
  
  DOI: 10.1111/acel.14077
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
2. scibot 19 Apr 2024
  
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  RRID:Addgene_40
  
  DOI: 10.1111/acel.14077
  
  Resource: RRID:Addgene_40823
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRIDCUR:Unresolved RRID:Addgene_40823
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RRID:Addgene_40823

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ncbi.nlm.nih.gov/pmc/articles/PMC11019121/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons

1
1. scibot 01 Aug 2023
  
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  RRID:Addgene_40823
  
  DOI: 10.1101/2023.07.19.549710
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
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  RRID:Addgene_40823
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ncbi.nlm.nih.gov/pmc/articles/PMC10370136/
May 2023
www.nature.com www.nature.com

Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance

1
1. scibot 05 May 2023
  
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  Plasmid_40823
  
  DOI: 10.1038/s41467-022-31905-0
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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nature.com/articles/s41467-022-31905-0
May 2022
www.sciencedirect.com www.sciencedirect.com

Reduction of phosphorylated α-synuclein through downregulation of casein kinase 2α alleviates dopaminergic-neuronal function

1
1. scibot 18 May 2022
  
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  plasmid_40823
  
  DOI: 10.1016/j.bbrc.2022.05.023
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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sciencedirect.com/science/article/pii/S0006291X22007197
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Roflupram attenuates α-synuclein-induced cytotoxicity and promotes the mitochondrial translocation of Parkin in SH-SY5Y cells overexpressing A53T mutant α-synuclein

1
1. scibot 05 Jan 2022
  
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  RRID:Addgene_40823
  
  DOI: 10.1016/j.taap.2021.115859
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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sciencedirect.com/science/article/pii/S0041008X21004634
Jun 2021
www.sciencedirect.com www.sciencedirect.com

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson’s disease

1
1. scibot 11 Jun 2021
  
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  RRID:Addgene_40823
  
  DOI: 10.1016/j.mcn.2021.103642
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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sciencedirect.com/science/article/pii/S1044743121000555
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In situ architecture of neuronal α-Synuclein inclusions

1
1. scibot 05 May 2021
  
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  RRID:Addgene_40823
  
  DOI: 10.1038/s41467-021-22108-0
  
  Resource: RRID:Addgene_40823
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823
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ncbi.nlm.nih.gov/pmc/articles/PMC8046968/
Feb 2021
www.nature.com www.nature.com

Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis

1
1. scibot 24 Feb 2021
  
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  RRID:Addgen_40823
  
  DOI: 10.1038/s41556-020-0535-7
  
  Resource: RRID:Addgene_40823
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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RRID:Addgene_40823

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nature.com/articles/s41556-020-0535-7
Jan 2020
www.frontiersin.org www.frontiersin.org

Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_40823
  
  DOI: 10.3389/fcell.2019.00191
  
  Resource: RRID:Addgene_40823
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_40823
  
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  RRID:Addgene_40823 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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frontiersin.org/articles/10.3389/fcell.2019.00191/full