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  1. Last 7 days
  2. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
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  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161652/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling
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    Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families from the Lynch Memorial Biobank reveals complex genetic architecture and phenocopies
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  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148166/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11139868/
  9. May 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Herpes simplex encephalitis due to a mutation in an E3 ubiquitin ligase
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    1. scibot 19 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11087577/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11099168/
  12. www.biorxiv.org www.biorxiv.org
    Context dependent activity of p63-bound gene regulatory elements
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      RRID:Addgene_41393

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  13. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 09 May 2024
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      DOI: 10.1126/sciadv.adl6082

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  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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    1. scibot 05 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  15. Apr 2024
  16. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
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  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment
    1
    1. scibot 18 Apr 2024
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      DOI: 10.3390/ijms25073950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011794/
  18. www.sciencedirect.com www.sciencedirect.com
    SHIP inhibition mediates select TREM2-induced microglial functions
    1
    1. scibot 16 Apr 2024
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    sciencedirect.com/science/article/pii/S0161589024000725
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
    1
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  20. Mar 2024
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    Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction
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  22. www.biorxiv.org www.biorxiv.org
    A Methodology for Specific Disruption of Microtubules in Dendritic Spines
    1
    1. scibot 21 Mar 2024
      RRID:Addgene_41393

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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein supersaturation powers innate immune signaling
    1
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A model of human neural networks reveals NPTX2 pathology in ALS and FTLD
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10901740/
  25. Feb 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of praja2 restrains endocytosis and boosts tyrosine kinase receptors in kidney cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879500/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_41393

      DOI: 10.1126/sciadv.adi3771

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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin targeting of the RNF12/RLIM E3 ubiquitin ligase controls transcriptional responses
    1
    1. scibot 08 Feb 2024
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  29. Jan 2024
  30. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  31. www.sciencedirect.com www.sciencedirect.com
    The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo
    1
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      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2023.113651

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    sciencedirect.com/science/article/pii/S2211124723016625
  32. Nov 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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      DOI: 10.1016/j.xcrm.2023.101290

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    sciencedirect.com/science/article/pii/S2666379123004846
  34. Sep 2023
  35. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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      DOI: 10.1016/j.celrep.2023.113084

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    sciencedirect.com/science/article/pii/S2211124723010951
  36. May 2023
  37. elifesciences.org elifesciences.org
    Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction
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    1. scibot 21 May 2023
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      DOI: 10.7554/eLife.82057

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  38. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
    1
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      DOI: 10.1016/j.celrep.2023.112472

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  39. Mar 2023
  40. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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    52.53.155.43/56dd9657520d89efd227b99f30a1871711d5fdb7/2023.01.31.526464v1.full-html.html
  41. www.biorxiv.org www.biorxiv.org
    The Dietary Supplement Taurine Suppresses Ovarian Cancer Growth
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    biorxiv.org/content/10.1101/2023.02.24.529893v1
  42. Feb 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
    1
    1. scibot 09 Feb 2023
      RRID:Addgene_41393

      DOI: 10.1158/2159-8290.CD-21-1672

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357213/
  44. Sep 2022
  45. www.sciencedirect.com www.sciencedirect.com
    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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    sciencedirect.com/science/article/pii/S2211124722012530
  46. Aug 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
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      DOI: 10.7554/eLife.73396

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    ncbi.nlm.nih.gov/pmc/articles/PMC9398446/
  48. Jul 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels
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      DOI: 10.3390/ijms23137337

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    ncbi.nlm.nih.gov/pmc/articles/PMC9266989/
  50. Apr 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Data-driven learning how oncogenic gene expression locally alters heterocellular networks
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
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      DOI: 10.3389/fgeed.2022.803375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8995503/
  54. www.nature.com www.nature.com
    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
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      DOI: 10.1038/s41418-022-00983-4

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    nature.com/articles/s41418-022-00983-4
  55. www.sciencedirect.com www.sciencedirect.com
    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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      Addgene plasmid # 41,393

      DOI: 10.1016/j.celrep.2022.110587

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    sciencedirect.com/science/article/pii/S221112472200331X
  56. Mar 2022
  57. www.embopress.org www.embopress.org
    Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma
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      DOI: 10.15252/embr.202154127

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    embopress.org/doi/abs/10.15252/embr.202154127
  58. Feb 2022
  59. www.sciencedirect.com www.sciencedirect.com
    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
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      plasmid_41393

      DOI: 10.1016/j.isci.2022.103806

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    sciencedirect.com/science/article/pii/S2589004222000761
  60. Oct 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
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      RRID:Addgene 41393

      DOI: 10.1016/j.cub.2021.09.067

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  62. www.sciencedirect.com www.sciencedirect.com
    CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement
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    1. scibot 21 Oct 2021
      RRID:Addgene_41393

      DOI: 10.1016/j.devcel.2021.09.023

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    sciencedirect.com/science/article/pii/S153458072100767X
  63. Sep 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
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    1. scibot 23 Sep 2021
      Addgene_41393

      DOI: 10.1016/j.molcel.2021.09.005

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  65. Aug 2021
  66. elifesciences.org elifesciences.org
    Untitled document
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      plasmid_41393

      DOI: 10.7554/eLife.31023

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  67. Jul 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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      Addgene41393

      DOI: 10.1016/j.ccell.2019.08.006

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  69. www.frontiersin.org www.frontiersin.org
    BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation
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    1. scibot 21 Jul 2021
      plasmid_41393

      DOI: 10.3389/fimmu.2021.683680

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  70. May 2021
  71. www.sciencedirect.com www.sciencedirect.com
    RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
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      plasmid_41393

      DOI: 10.1016/j.devcel.2021.04.022

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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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    1. scibot 07 May 2021
      RRID:Addgene_41393

      DOI: 10.1016/j.molcel.2020.04.031

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  73. Apr 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
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    1. scibot 21 Apr 2021
      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2021.109010

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  75. www.nature.com www.nature.com
    The white matter is a pro-differentiative niche for glioblastoma
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      RRID:Addgene_41393

      DOI: 10.1038/s41467-021-22225-w

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  76. Jan 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer
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    1. scibot 07 Jan 2021
      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2020.108585

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  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
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      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2020.02.090

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    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      RRID:Addgene_41393

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
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    Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes
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      RRID:Addgene_41393

      DOI: 10.1016/j.redox.2020.101429

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  82. elifesciences.org elifesciences.org
    KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
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    1. scibot 09 Sep 2020
      RRID:Addgene_41393

      DOI: 10.7554/eLife.56337

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