75 Matching Annotations
  1. Oct 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
    1
    1. scibot 09 Oct 2024
      AddgeneCat# 41393

      DOI: 10.1016/j.cell.2024.09.024

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    sciencedirect.com/science/article/pii/S0092867424010729
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Grb2 SH3 Domains with Affimer Proteins Provides Novel Insights into Ras Signalling Modulation
    1
    1. scibot 29 Sep 2024
      41393

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    ncbi.nlm.nih.gov/pmc/articles/PMC11352564/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade
    1
    1. scibot 29 Sep 2024
      41393

      DOI: 10.1038/s41467-024-51828-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11364849/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations
    1
    1. scibot 29 Sep 2024
      plasmid_41393

      DOI: 10.1101/2024.08.22.609165

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    ncbi.nlm.nih.gov/pmc/articles/PMC11370454/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic Effect of Ubiquitin-Specific Protease 14 and Poly(ADP-Ribose) Glycohydrolase Co-Inhibition in BRCA1-Mutant, Poly(ADP-Ribose) Polymerase Inhibitor-Resistant Triple-Negative Breast Cancer Cells
    1
    1. scibot 28 Sep 2024
      41393

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    ncbi.nlm.nih.gov/pmc/articles/PMC11385694/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity
    1
    1. scibot 27 Sep 2024
      41393

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    ncbi.nlm.nih.gov/pmc/articles/PMC11383994/
  9. www.sciencedirect.com www.sciencedirect.com
    The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
    1
    1. scibot 13 Sep 2024
      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2024.114689

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    sciencedirect.com/science/article/pii/S2211124724010404
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
    1
    1. scibot 23 Aug 2024
      RRID# Addgene_41393

      DOI: 10.1158/2767-9764.CRC-24-0024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11337092/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human stem cell–derived neurons and astrocytes to detect novel auto-reactive IgG response in immune-mediated neurological diseases
    1
    1. scibot 22 Aug 2024
      Addgene_41393

      DOI: 10.3389/fimmu.2024.1419712

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    ncbi.nlm.nih.gov/pmc/articles/PMC11303155/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Involvement of the splicing factor SART1 in the BRCA1-dependent homologous recombination repair of DNA double-strand breaks
    1
    1. scibot 22 Aug 2024
      Addgene_41393

      DOI: 10.1038/s41598-024-68926-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310344/
  14. www.sciencedirect.com www.sciencedirect.com
    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
    2
    1. scibot 20 Aug 2024
      RRID:Addgene_41393

      DOI: 10.1016/j.molcel.2024.07.013

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    2. scibot 13 Aug 2024
      Addgene_41393

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    sciencedirect.com/science/article/pii/S1097276524005896
  15. www.sciencedirect.com www.sciencedirect.com
    A High-Throughput Screening Identifies MCM Chromatin loading Inhibitors Targeting Cells with increased Replication Origins
    1
    1. scibot 19 Aug 2024
      RRID:Addgene_41393

      DOI: 10.1016/j.isci.2024.110567

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    sciencedirect.com/science/article/pii/S2589004224017929
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair
    1
    1. scibot 18 Aug 2024
      41393

      DOI: 10.1126/sciadv.ado0636

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    ncbi.nlm.nih.gov/pmc/articles/PMC11313846/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth
    1
    1. scibot 02 Aug 2024
      pCW57.1

      DOI: 10.1038/s41467-024-45691-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867020/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
    1
    1. scibot 02 Aug 2024
      Addgene41393

      DOI: 10.1016/j.celrep.2022.111818

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265649/
  19. Jul 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highlights from MBoC Selection: A methodology for specific disruption of microtubule polymerization into dendritic spines
    1
    1. scibot 30 Jul 2024
      RRID:Addgene_41393

      DOI: 10.1091/mbc.E24-02-0093

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    ncbi.nlm.nih.gov/pmc/articles/PMC11238079/
  21. elifesciences.org elifesciences.org
    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
    1
    1. scibot 04 Jul 2024
      Addgene plasmid 41393

      DOI: 10.7554/eLife.98649

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      RRID:Addgene_41393 DOI:10.7554/eLife.98649
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    elifesciences.org/articles/98649
  22. Jun 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
    1
    1. scibot 21 Jun 2024
      Addgene_41393

      DOI: 10.1038/s41467-024-49391-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161652/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling
    1
    1. scibot 15 Jun 2024
      pCW57.1

      DOI: 10.1038/s41467-024-49260-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166935/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted sequencing for hereditary breast and ovarian cancer in BRCA1/2-negative families from the Lynch Memorial Biobank reveals complex genetic architecture and phenocopies
    1
    1. scibot 14 Jun 2024
      RRID:Addgene_41393

      DOI: 10.1016/j.xhgg.2024.100306

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166883/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling
    1
    1. scibot 10 Jun 2024
      41393

      DOI: 10.1038/s44318-024-00092-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148166/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TCF7L1 regulates colorectal cancer cell migration by repressing GAS1 expression
    1
    1. scibot 03 Jun 2024
      pCW57.1-empty

      DOI: 10.1038/s41598-024-63346-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11139868/
  28. May 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Herpes simplex encephalitis due to a mutation in an E3 ubiquitin ligase
    1
    1. scibot 19 May 2024
      plasmid_41393

      DOI: 10.1038/s41467-024-48287-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11087577/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response
    1
    1. scibot 19 May 2024
      Addgene_41393

      DOI: 10.1038/s42003-024-06288-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11099168/
  31. www.biorxiv.org www.biorxiv.org
    Context dependent activity of p63-bound gene regulatory elements
    1
    1. scibot 17 May 2024
      RRID:Addgene_41393

      DOI: 10.1101/2024.05.09.593326

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    biorxiv.org/content/10.1101/2024.05.09.593326v1
  32. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 09 May 2024
      RRID:Addgene_41393

      DOI: 10.1126/sciadv.adl6082

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    science.org/doi/10.1126/sciadv.adl6082
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 05 May 2024
      RRID:Addgene_41393

      DOI: 10.1126/sciadv.adl6082

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  34. Apr 2024
  35. www.pnas.org www.pnas.org
    NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells
    1
    1. scibot 25 Apr 2024
      addgene_41393

      DOI: 10.1073/pnas.2314695121

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    pnas.org/doi/abs/10.1073/pnas.2314695121
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment
    1
    1. scibot 18 Apr 2024
      RRID:Addgene_41393

      DOI: 10.3390/ijms25073950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011794/
  37. www.sciencedirect.com www.sciencedirect.com
    SHIP inhibition mediates select TREM2-induced microglial functions
    1
    1. scibot 16 Apr 2024
      Addgene_41393

      DOI: 10.1016/j.molimm.2024.04.002

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    sciencedirect.com/science/article/pii/S0161589024000725
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
    1
    1. scibot 14 Apr 2024
      41393

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
  39. Mar 2024
  40. link.springer.com link.springer.com
    Altered vacuole membrane protein 1 (VMP1) expression is associated with increased NLRP3 inflammasome activation and mitochondrial dysfunction
    1
    1. scibot 22 Mar 2024
      plasmid_41393

      DOI: 10.1007/s00011-024-01856-x

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    link.springer.com/article/10.1007/s00011-024-01856-x
  41. www.biorxiv.org www.biorxiv.org
    A Methodology for Specific Disruption of Microtubules in Dendritic Spines
    1
    1. scibot 21 Mar 2024
      RRID:Addgene_41393

      DOI: 10.1101/2024.03.04.583370

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    biorxiv.org/content/10.1101/2024.03.04.583370v1
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein supersaturation powers innate immune signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10055258/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A model of human neural networks reveals NPTX2 pathology in ALS and FTLD
    1
    1. scibot 08 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10901740/
  44. Feb 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of praja2 restrains endocytosis and boosts tyrosine kinase receptors in kidney cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879500/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_41393

      DOI: 10.1126/sciadv.adi3771

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881058/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin targeting of the RNF12/RLIM E3 ubiquitin ligase controls transcriptional responses
    1
    1. scibot 08 Feb 2024
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      DOI: 10.26508/lsa.202302282

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    ncbi.nlm.nih.gov/pmc/articles/PMC10781586/
  48. Jan 2024
  49. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
    1
    1. scibot 25 Jan 2024
      Addgene_41393

      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  50. www.sciencedirect.com www.sciencedirect.com
    The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo
    1
    1. scibot 11 Jan 2024
      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2023.113651

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    sciencedirect.com/science/article/pii/S2211124723016625
  51. Nov 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
    1. scibot 22 Nov 2023
      RRID:Addgene_41393

      DOI: 10.1016/j.xcrm.2023.101290

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    sciencedirect.com/science/article/pii/S2666379123004846
  53. Sep 2023
  54. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
    1
    1. scibot 19 Sep 2023
      RRID:Addgene_41393

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  55. May 2023
  56. elifesciences.org elifesciences.org
    Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction
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      plasmid_41393

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  57. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
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  58. Mar 2023
  59. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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  60. www.biorxiv.org www.biorxiv.org
    The Dietary Supplement Taurine Suppresses Ovarian Cancer Growth
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  61. Feb 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
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  63. Sep 2022
  64. www.sciencedirect.com www.sciencedirect.com
    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
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      pCW57.1

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  65. Aug 2022
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
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  67. Jul 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels
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  69. Apr 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Data-driven learning how oncogenic gene expression locally alters heterocellular networks
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
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      Addgene41393

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
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      RRID:Addgene_41393

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  73. www.nature.com www.nature.com
    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
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  74. www.sciencedirect.com www.sciencedirect.com
    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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      Addgene plasmid # 41,393

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  75. Mar 2022
  76. www.embopress.org www.embopress.org
    Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma
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      Plasmid_41393

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  77. Feb 2022
  78. www.sciencedirect.com www.sciencedirect.com
    TRACE-seq: A transgenic system for unbiased and non-invasive transcriptome profiling of living cells
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      plasmid_41393

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    sciencedirect.com/science/article/pii/S2589004222000761
  79. Oct 2021
  80. www.sciencedirect.com www.sciencedirect.com
    Exocyst complex mediates recycling of internal cilia
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      RRID:Addgene 41393

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  81. www.sciencedirect.com www.sciencedirect.com
    CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagement
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      RRID:Addgene_41393

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    sciencedirect.com/science/article/pii/S153458072100767X
  82. Sep 2021
  83. www.sciencedirect.com www.sciencedirect.com
    Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
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      Addgene_41393

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    sciencedirect.com/science/article/pii/S1097276521007395
  84. Aug 2021
  85. elifesciences.org elifesciences.org
    Untitled document
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      plasmid_41393

      DOI: 10.7554/eLife.31023

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  86. Jul 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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    1. scibot 29 Jul 2021
      Addgene41393

      DOI: 10.1016/j.ccell.2019.08.006

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    sciencedirect.com/science/article/pii/S1535610819303745
  88. www.frontiersin.org www.frontiersin.org
    BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation
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      plasmid_41393

      DOI: 10.3389/fimmu.2021.683680

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    frontiersin.org/article/10.3389/fimmu.2021.683680/full
  89. May 2021
  90. www.sciencedirect.com www.sciencedirect.com
    RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
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      plasmid_41393

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  91. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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      RRID:Addgene_41393

      DOI: 10.1016/j.molcel.2020.04.031

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    sciencedirect.com/science/article/pii/S1097276520302732
  92. Apr 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
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      RRID:Addgene_41393

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    sciencedirect.com/science/article/pii/S2211124721003247
  94. www.nature.com www.nature.com
    The white matter is a pro-differentiative niche for glioblastoma
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      RRID:Addgene_41393

      DOI: 10.1038/s41467-021-22225-w

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    nature.com/articles/s41467-021-22225-w
  95. Jan 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer
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      RRID:Addgene_41393

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  97. Sep 2020
  98. www.sciencedirect.com www.sciencedirect.com
    Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
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      RRID:Addgene_41393

      DOI: 10.1016/j.celrep.2020.02.090

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  99. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      RRID:Addgene_41393

      DOI: 10.1016/j.cell.2020.03.040

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  100. www.sciencedirect.com www.sciencedirect.com
    Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes
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      RRID:Addgene_41393

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  101. elifesciences.org elifesciences.org
    KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
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      RRID:Addgene_41393

      DOI: 10.7554/eLife.56337

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