77 Matching Annotations
  1. Last 7 days
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    ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology
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    sciencedirect.com/science/article/pii/S1097276526005137
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sphingosine-1-phosphate receptor 1 signaling stimulates human pluripotent stem cell-derived cardiomyocyte differentiation and maturation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13434232/
  5. Jul 2026
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    Psoriasis-risk SNP rs610604 reveals nuclear IKKα–TNFAIP3 repressor axis driving autoinflammatory circuits
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    sciencedirect.com/science/article/pii/S0022202X26026771
  7. Jun 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAD54L promotes nascent DNA degradation and radial chromosome formation in FANC-deficient cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13192876/
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    Human pluripotent stem cell engineering with CRISPR–Cas9 for Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13144315/
  10. Feb 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Screening strategy to identify Cas9 variants with higher HDR activity based on diphtheria toxin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12673799/
  12. Nov 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytosine methylase and hydroxymethylase activity in mammalian mitochondria
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  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9 generated DSB clusters mimic complex lesions induced by high-LET radiation and shift repair from c-NHEJ to mutagenic repair pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12537819/
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    Development of programmable RNA imaging with RNA-guided GFP via click chemistry
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  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loop engineering of AtCas9 for effective and broad genome editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12634846/
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    Identification of Potential Therapeutic Agents for Type I Interferonopathy Using iPSC-Based Disease Modeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12484275/
  18. Aug 2025
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    MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition
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    sciencedirect.com/science/article/pii/S2211124725009519
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    Conserved and unique features of terminal telomeric sequences in ALT-positive cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316455/
  21. Jul 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12241343/
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    Transcription Factor-Wide Association Studies to Identify Functional SNPs in Alzheimer's Disease
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    Repeat length as a key determinant for disease severity and antisense oligonucleotide activity in myotonic dystrophy type 1
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  25. Jun 2025
  26. www.cell.com www.cell.com
    Phase separation of TTBK2 and CEP164 is necessary for ciliogenesis
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    cell.com/cell-reports/fulltext/S2211-1247(25)00581-9
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    Beyond Trypanosoma cruzi: LINE-1 Activation as a Driver of Chronic Inflammation in Chagas Disease
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    Identification of maternal allele sequences of IG-DMR that are essential for neonatal viability
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  29. Apr 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light-induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11925727/
  31. Mar 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KNTC1 introduces segmental heterogeneity to mitochondria
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    Dual-directional epi-genotoxicity assay for assessing chemically induced epigenetic effects utilizing the housekeeping TK gene
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  34. Jan 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GATA4 binding to the Sox9 enhancer mXYSRa/Enh13 is critical for testis differentiation in mouse
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  37. Dec 2024
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid Nanoparticles Enable Efficient In Vivo DNA Knock-In via HITI-Mediated Genome Editing
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  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cells are all-right: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells
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    Perinuclear assembly of vimentin intermediate filaments induces cancer cell nuclear dysmorphia
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  41. Sep 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation and analysis of mouse embryonic stem cells with knockout of the Mcph1 (microcephalin) gene
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    Generation of a fluorescent mNeonGreen insulin reporter line in the H1 (WA01) hESC background
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  44. Aug 2024
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    Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
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    Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants
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    pubs.acs.org/doi/full/10.1021/acssynbio.3c00355
  47. Jul 2024
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
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  49. May 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
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    Assessing cell lines with inducible depletion of cohesin and condensins components through analysis of metaphase chromosome morphology
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    ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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  54. Apr 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transduction and Genome Editing of the Heart with Adeno-Associated Viral Vectors Loaded onto Electrospun Polydioxanone Nonwoven Fabrics
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    Progesterone-mediated remodeling of the maternal-fetal interface by a PGRMC1-dependent mechanism
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    Evolution of a novel regulatory mechanism of hypoxia inducible factor in hypoxia-tolerant electric fishes
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    Promoting the production of challenging proteins via induced expression in CHO cells and modified cell-free lysates harboring T7 RNA polymerase and mutant eIF2α
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  60. 52.53.155.43 52.53.155.43
    Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q
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  61. Feb 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SpCas9-HF1 enhances accuracy of cell cycle-dependent genome editing by increasing HDR efficiency, and by reducing off-target effects and indel rates
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Pigmentation Does Not Affect Light-Activated Belzupacap Sarotalocan Treatment but Influences Macrophage Polarization in a Murine Melanoma Model
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    Fluorogenic CRISPR for genomic DNA imaging
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    Absence of the RING domain in MID1 results in patterning defects in the developing human brain
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    ncbi.nlm.nih.gov/pmc/articles/PMC10796562/
  66. Dec 2023
  67. pubs.acs.org pubs.acs.org
    Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants
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  68. Nov 2023
  69. www.biorxiv.org www.biorxiv.org
    A Proximal Sox2 Enhancer Cluster is Required for the Anterior Regional Identity of Neural Progenitors
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  70. Oct 2023
  71. 52.53.155.43 52.53.155.43
    BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
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  72. Sep 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10505916/
  74. Aug 2023
  75. www.biorxiv.org www.biorxiv.org
    Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q
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    Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function
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  77. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
  78. Jun 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo18F-DOPA PET imaging identifies a dopaminergic deficit in a rat model with a G51D α-synuclein mutation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10244711/
  80. Jan 2023
  81. www.nature.com www.nature.com
    Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation
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    nature.com/articles/s41467-023-36116-9
  82. May 2022
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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  84. Mar 2022
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    PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production
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    nature.com/articles/s41388-022-02219-8
  86. Dec 2021
  87. www.mdpi.com www.mdpi.com
    Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma
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    mdpi.com/2072-6694/13/24/6197
  88. Nov 2021
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    An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity
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    sciencedirect.com/science/article/pii/S0896627321007820
  90. Oct 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of CRISPR/Cas9 Guide RNA Efficiency and Specificity Against Genetically Diverse HIV-1 Isolates
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    ncbi.nlm.nih.gov/pmc/articles/PMC7549012/
  92. Aug 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo
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    sciencedirect.com/science/article/pii/S1931312817305450
  94. Jul 2021
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    sciencedirect.com/science/article/pii/S1934590918305927
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    Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
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    sciencedirect.com/science/article/pii/S1934590918302388
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    Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
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    nature.com/articles/s41422-019-0213-0
  98. www.sciencedirect.com www.sciencedirect.com
    The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency
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    sciencedirect.com/science/article/pii/S002192582100747X
  99. May 2021
  100. www.sciencedirect.com www.sciencedirect.com
    A Non-Coding Disease Modifier of Pancreatic Agenesis Identified by Genetic Correction in a Patient-Derived iPSC Line
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    sciencedirect.com/science/article/pii/S1934590920301995
  101. Apr 2021
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    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590921001119
  103. Mar 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Study of the effect of the introduction of mitochondrial import determinants into the gRNA structure on the activity of the gRNA/SpCas9 complex in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC7716540/
  105. Feb 2021
  106. www.embopress.org www.embopress.org
    Transcriptionally active enhancers in human cancer cells
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    embopress.org/doi/abs/10.15252/msb.20209873
  107. Nov 2020
  108. www.sciencedirect.com www.sciencedirect.com
    Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S2666166720301453
  109. Sep 2020
  110. www.mdpi.com www.mdpi.com
    Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer
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    mdpi.com/2072-6694/12/5/1325
  111. www.sciencedirect.com www.sciencedirect.com
    A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S1934590920301569
  112. Jan 2020
  113. www.sciencedirect.com www.sciencedirect.com
    HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis
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    sciencedirect.com/science/article/pii/S2211124719307351
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32644
  115. www.sciencedirect.com www.sciencedirect.com
    Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
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    sciencedirect.com/science/article/pii/S1934590918302388
  116. www.sciencedirect.com www.sciencedirect.com
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