74 Matching Annotations
  1. Last 7 days
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    Generation of spermatogonia from human and non-human primate pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590926002298
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    ERK1/2 function as a central hub safeguarding primed human embryonic stem cell identity via multifaceted regulatory networks
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    sciencedirect.com/science/article/pii/S2211124726007539
  4. Apr 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11244999/
  6. Mar 2026
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    Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells
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    sciencedirect.com/science/article/pii/S193459092600072X
  8. Feb 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual pathways via CENP-C and Mis18C recruit HJURP for CENP-A deposition into vertebrate centromeres
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    pmc.ncbi.nlm.nih.gov/articles/PMC12910082/
  10. Nov 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MuRF1 Partners With TRIM72 to Impair Insulin Signaling in Skeletal Muscle Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12464895/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inducible tag-free degradation of endogenous proteins with AlissAID and development of a photoactivable inducer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603123/
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    Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks
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    sciencedirect.com/science/article/pii/S1097276525008561
  14. Sep 2025
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    Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
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    sciencedirect.com/science/article/pii/S2666979X25002423
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12404203/
  17. Aug 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262574/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphoinositide‐ and Collybistin‐Dependent Synaptic Clustering of Gephyrin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12334862/
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    Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
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    sciencedirect.com/science/article/pii/S1097276525006070
  21. Jul 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12203905/
  23. Jun 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cell-context response to germ layer differentiation signals is predetermined by the epigenome in regionalized epiblast populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122723/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in the tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12089342/
  26. May 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPDPF is not a key regulator of human pancreas development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12037078/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recombinant PRV Expressing GP3 and GP5 of PRRSV Provides Effective Protection Against Coinfection With PRV and PRRSV
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081148/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12063660/
  30. Apr 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FGFR2 residence in primary cilia is necessary for epithelial cell signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010920/
  32. dx.doi.org dx.doi.org
    Structure of the nucleosome-bound human BCL7A
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    dx.doi.org/10.1093/nar/gkaf273
  33. Mar 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Opposing roles for Bmp signalling during the development of electrosensory lateral line organs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11936418/
  35. Feb 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11848802/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Correction to “Development of BromoTag: A “Bump-and-Hole”–PROTAC System To Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins”
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831586/
  38. www.cell.com www.cell.com
    CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer
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    cell.com/cell-reports/fulltext/S2211-1247(25)00083-X
  39. Sep 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343218/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The characteristics of CTCF binding sequences contribute to enhancer blocking activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11417384/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11418197/
  43. Jun 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH
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    ncbi.nlm.nih.gov/pmc/articles/PMC11194096/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer-associated MDM2 W329G mutant attenuates ribosomal stress-mediated p53 responses to promote cell survival and glycolysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11162693/
  46. May 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11116810/
  48. www.biorxiv.org www.biorxiv.org
    Mammalian RNAi represses pericentromeric lncRNAs to maintain genome stability
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    biorxiv.org/content/10.1101/2024.05.09.593425v1
  49. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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    sciencedirect.com/science/article/pii/S1097276524003290
  50. www.sciencedirect.com www.sciencedirect.com
    Generation of a human induced pluripotent stem cell line JHUi004-A with heterozygous mutation for spinocerebellar ataxia type 12 using genome editing
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    sciencedirect.com/science/article/pii/S1873506124001399
  51. www.biorxiv.org www.biorxiv.org
    ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway
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    biorxiv.org/content/10.1101/2024.01.17.576039v1
  52. Apr 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification
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    ncbi.nlm.nih.gov/pmc/articles/PMC10946437/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STIM1 translocation to the nucleus protects cells from DNA damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10954485/
  55. Mar 2024
  56. www.sciencedirect.com www.sciencedirect.com
    Generation of SST-P2A-mCherry reporter human embryonic stem cell line using the CRISPR/Cas9 system (WAe001-A-2C)
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    sciencedirect.com/science/article/pii/S1873506124000953
  57. Feb 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of CRISPR/Cas9 for Rapid Genome Editing of Pseudorabies Virus and Bovine Herpesvirus-1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10892916/
  59. Aug 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of branch site recognition by the human spliceosome
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614990/
  61. www.sciencedirect.com www.sciencedirect.com
    Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
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    sciencedirect.com/science/article/pii/S1097276523005671
  62. Jun 2023
  63. www.sciencedirect.com www.sciencedirect.com
    Centromere/kinetochore is assembled through CENP-C oligomerization
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    sciencedirect.com/science/article/pii/S1097276523003799
  64. May 2023
  65. 52.53.155.43 52.53.155.43
    Necessity of HuR/ELAVL1 for activation-induced cytidine deaminase-dependent decrease in topoisomerase 1 in antibody diversification
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    52.53.155.43/48689241604aa0ddda1ea4c5de857e353548cf3a/dxad011-html.html
  66. Feb 2023
  67. www.nature.com www.nature.com
    ADAMTS4 is involved in the production of the Alzheimer disease amyloid biomarker APP669-711
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    nature.com/articles/s41380-023-01946-y
  68. elifesciences.org elifesciences.org
    T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
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    elifesciences.org/articles/83077
  69. Jan 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
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    ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
  71. Nov 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1534580722007626
  73. May 2022
  74. www.sciencedirect.com www.sciencedirect.com
    Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons
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    sciencedirect.com/science/article/pii/S0960982222006716
  75. Mar 2022
  76. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9-engineered human ES cells harboring heterozygous and homozygous c-KIT knockout
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    sciencedirect.com/science/article/pii/S1873506122000812
  77. Nov 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
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    sciencedirect.com/science/article/pii/S089662732100862X
  79. Oct 2021
  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Gene trapping reveals a new transcriptionally active genome element: the chromosome-specific clustered trap region
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    onlinelibrary.wiley.com/doi/10.1111/gtc.12890
  81. Sep 2021
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC8391736/
  83. Aug 2021
  84. link.springer.com link.springer.com
    New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells
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    link.springer.com/article/10.1007/s12015-021-10232-9
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC5602299/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
  87. Jul 2021
  88. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/26876
  89. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family
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    sciencedirect.com/science/article/pii/S2211124719314767
  90. Apr 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Generation of a human induced pluripotent stem cell line JHUi003-A with homozygous mutation for spinocerebellar ataxia type 12 using genome editing
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    sciencedirect.com/science/article/pii/S1873506121001926
  92. Mar 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background
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    ncbi.nlm.nih.gov/pmc/articles/PMC7940647/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program
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    ncbi.nlm.nih.gov/pmc/articles/PMC7918644/
  95. Feb 2021
  96. elifesciences.org elifesciences.org
    Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance
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    elifesciences.org/articles/36262
  97. Dec 2020
  98. www.sciencedirect.com www.sciencedirect.com
    The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism
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    sciencedirect.com/science/article/pii/S2213231720310053
  99. Nov 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Essentiality of CENP-A Depends on Its Binding Mode to HJURP
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    sciencedirect.com/science/article/pii/S2211124720313772
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of human immortalized mesenchymal stem cells lines for the monitoring and analysis of osteogenic differentiation in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7610338/
  102. Sep 2020
  103. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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    sciencedirect.com/science/article/pii/S221112472031189X
  104. elifesciences.org elifesciences.org
    Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance
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    elifesciences.org/articles/36262
  105. Jan 2020
  106. elifesciences.org elifesciences.org
    PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
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    elifesciences.org/articles/50416
  107. www.jbc.org www.jbc.org
    The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export
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    jbc.org/content/294/30/11597.full
  108. www.sciencedirect.com www.sciencedirect.com
    SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance
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    sciencedirect.com/science/article/pii/S1097276519305404
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4
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    ncbi.nlm.nih.gov/pmc/articles/PMC6881147/