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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer
    1
    1. scibot 23 Apr 2024
      44012

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009390/
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quaking isoforms cooperate to promote the mesenchymal phenotype
    1
    1. scibot 15 Apr 2024
      Addgene_44012

      DOI: 10.1091/mbc.E23-08-0316

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881146/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The DNA Damage Response (DDR) landscape of endometrial cancer defines discrete disease subtypes and reveals therapeutic opportunities
    1
    1. scibot 13 Apr 2024
      44012

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000323/
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
      Plasmid_44012

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    sciencedirect.com/science/article/pii/S1097276524001758
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer
    1
    1. scibot 08 Mar 2024
      pInducer20

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    ncbi.nlm.nih.gov/pmc/articles/PMC10911929/
  9. Feb 2024
  10. www.biorxiv.org www.biorxiv.org
    KDM6A Regulates Immune Response Genes in Multiple Myeloma
    1
    1. scibot 22 Feb 2024
      RRID:Addgene 44012

      DOI: 10.1101/2024.02.12.579179

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    biorxiv.org/content/10.1101/2024.02.12.579179v1
  11. www.sciencedirect.com www.sciencedirect.com
    Specialized replication mechanisms maintain genome stability at human centromeres
    2
    1. scibot 15 Feb 2024
      Addgene_44012

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    sciencedirect.com/science/article/pii/S1097276524000546
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation
    1
    1. scibot 13 Feb 2024
      44012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10760953/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells
    1
    1. scibot 08 Feb 2024
      Plasmid_44012

      DOI: 10.1038/s41420-023-01772-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10770371/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic proximity interaction profiling suggests that YPEL2 is involved in cellular stress surveillance
    1
    1. scibot 05 Feb 2024
      Plasmid_44012

      DOI: 10.1002/pro.4859

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    ncbi.nlm.nih.gov/pmc/articles/PMC10804680/
  15. Jan 2024
  16. www.sciencedirect.com www.sciencedirect.com
    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
    2
    1. scibot 25 Jan 2024
      pInducer20Addgene44012

      DOI: 10.1016/j.molcel.2023.12.040

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      plasmid_44012

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    sciencedirect.com/science/article/pii/S1097276523010869
  17. Dec 2023
  18. journals.plos.org journals.plos.org
    Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks
    1
    1. scibot 16 Dec 2023
      RRID:Addgene_44012

      DOI: 10.1371/journal.ppat.1009460

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    journals.plos.org/plospathogens/article
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF524 directly interacts with telomeric DNA and supports telomere integrity
    1
    1. scibot 15 Dec 2023
      RRID:Addgene_44012

      DOI: 10.1038/s41467-023-43397-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10716145/
  20. Nov 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas
    1
    1. scibot 22 Nov 2023
      RRID:Addgene_44012

      DOI: 10.1016/j.celrep.2023.113470

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    sciencedirect.com/science/article/pii/S2211124723014821
  22. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
    1
    1. scibot 22 Nov 2023
      Addgene_44012

      DOI: 10.1016/j.celrep.2023.113478

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    sciencedirect.com/science/article/pii/S2211124723014900
  23. www.biorxiv.org www.biorxiv.org
    APC/C prevents non-canonical order of cyclin/CDK activity to maintain CDK4/6 inhibitor-induced arrest
    1
    1. scibot 17 Nov 2023
      plasmid_44012

      DOI: 10.1101/2023.11.09.566394

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    biorxiv.org/content/10.1101/2023.11.09.566394v1
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS
    1
    1. scibot 04 Nov 2023
      plasmid_44012

      DOI: 10.1016/j.isci.2023.108168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
    1
    1. scibot 28 Oct 2023
      RRID:Addgene_44012

      DOI: 10.1016/j.molcel.2023.09.034

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    sciencedirect.com/science/article/pii/S1097276523008006
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells
    1
    1. scibot 14 Oct 2023
      RRID:Addgene_44012

      DOI: 10.3389/fcell.2023.1236356

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    ncbi.nlm.nih.gov/pmc/articles/PMC10565211/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP
    1
    1. scibot 05 Oct 2023
      plasmid_44012

      DOI: 10.7554/eLife.92409

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    ncbi.nlm.nih.gov/pmc/articles/PMC10541173/
  29. Sep 2023
  30. dx.doi.org dx.doi.org
    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
    1
    1. scibot 22 Sep 2023
      Addgene_44012

      DOI: 10.1093/nar/gkad733

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    dx.doi.org/10.1093/nar/gkad733
  31. Jun 2023
  32. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
    1
    1. scibot 23 Jun 2023
      RRID:Addgene_44012

      DOI: 10.1016/j.ccell.2023.06.001

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    sciencedirect.com/science/article/pii/S1535610823002088
  33. May 2023
  34. www.mdpi.com www.mdpi.com
    TGF-β Type I Receptor Signaling in Melanoma Liver Metastases Increases Metastatic Outgrowth
    1
    1. scibot 18 May 2023
      RRID:Addgene_44012

      DOI: 10.3390/ijms24108676

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    mdpi.com/1422-0067/24/10/8676
  35. Mar 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin
    1
    1. scibot 09 Mar 2023
      RRID:Addgene_4401

      DOI: 10.1016/j.isci.2023.106150

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    ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
    1
    1. scibot 04 Mar 2023
      plasmid_44012

      DOI: 10.1016/j.xcrm.2023.100937

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    ncbi.nlm.nih.gov/pmc/articles/PMC9975292/
  38. Feb 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression
    1
    1. scibot 09 Feb 2023
      RRID:Addgene_44012

      DOI: 10.1158/1541-7786.MCR-22-0111

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357060/
  40. www.sciencedirect.com www.sciencedirect.com
    A FRET sensor for the real-time detection of long chain acyl-CoAs and synthetic ABHD5 ligands
    1
    1. scibot 01 Feb 2023
      Addgene_44012

      DOI: 10.1016/j.crmeth.2023.100394

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    sciencedirect.com/science/article/pii/S2667237523000012
  41. Jan 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CoQ Regulates Brown Adipose Tissue Respiration and Uncoupling Protein 1 Expression
    1
    1. scibot 25 Jan 2023
      RRID:Addgene_44012

      DOI: 10.3390/antiox12010014

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    ncbi.nlm.nih.gov/pmc/articles/PMC9854525/
  43. Nov 2022
  44. www.nature.com www.nature.com
    Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
    1
    1. scibot 19 Nov 2022
      RRID:Addgene_44012

      DOI: 10.1038/s41467-022-34776-7

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    nature.com/articles/s41467-022-34776-7
  45. Oct 2022
  46. www.nature.com www.nature.com
    The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma
    1
    1. scibot 28 Oct 2022
      Addgene_44012

      DOI: 10.1038/s41467-022-33746-3

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    nature.com/articles/s41467-022-33746-3
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures
    1
    1. scibot 14 Oct 2022
      Plasmid_44012

      DOI: 10.1016/j.isci.2022.105200

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550643/
  48. Aug 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
    1
    1. scibot 23 Aug 2022
      plasmid_44012

      DOI: 10.1016/j.molcel.2022.07.014

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    sciencedirect.com/science/article/pii/S1097276522007109
  50. www.sciencedirect.com www.sciencedirect.com
    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
    1
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      Addgene_44012

      DOI: 10.1016/j.celrep.2022.111192

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    sciencedirect.com/science/article/pii/S2211124722010099
  51. Jun 2022
  52. 52.53.155.43 52.53.155.43
    mcr-22-0111-html.html
    2
    1. scibot 30 Jun 2022
      RRID:Addgene_44012

      DOI: 10.1158/1541-7786.mcr-22-0111

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      RRID:Addgene_44012

      DOI: 10.1158/1541-7786.mcr-22-0111

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    52.53.155.43/b6d51cceb9331705a006fdd17f4e296068136f74/mcr-22-0111 (1)-html.html
  53. www.nature.com www.nature.com
    TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors
    1
    1. scibot 22 Jun 2022
      RRID:Addgene_44012

      DOI: 10.1038/s41590-022-01232-z

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    nature.com/articles/s41590-022-01232-z
  54. www.sciencedirect.com www.sciencedirect.com
    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
    1
    1. scibot 15 Jun 2022
      AddgeneCat. No.: 44012

      DOI: 10.1016/j.celrep.2022.110944

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    sciencedirect.com/science/article/pii/S2211124722007264
  55. Mar 2022
  56. www.sciencedirect.com www.sciencedirect.com
    Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator
    1
    1. scibot 04 Mar 2022
      RRID:Addgene_44012

      DOI: 10.1016/j.bbagrm.2022.194801

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    sciencedirect.com/science/article/pii/S1874939922000165
  57. Feb 2022
  58. www.sciencedirect.com www.sciencedirect.com
    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
    1
    1. scibot 23 Feb 2022
      AddgeneCat# 44012

      DOI: 10.1016/j.molcel.2022.01.015

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    sciencedirect.com/science/article/pii/S1097276522000582
  59. Dec 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
    1
    1. scibot 17 Dec 2021
      RRID:Addgene_44012

      DOI: 10.7554/eLife.70691

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    ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
  61. Nov 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay
    1
    1. scibot 05 Nov 2021
      RRID:Addgene_44012

      DOI: 10.7554/eLife.71966

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553338/
  63. Oct 2021
  64. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
    1
    1. scibot 29 Oct 2021
      RRID:Addgene_44012

      DOI: 10.1016/j.isci.2021.103224

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    sciencedirect.com/science/article/pii/S2589004221011925
  65. Aug 2021
  66. journals.plos.org journals.plos.org
    Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers
    1
    1. scibot 18 Aug 2021
      RRID:Addgene_44012

      DOI: 10.1371/journal.ppat.1009863

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    journals.plos.org/plospathogens/article
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    1
    1. scibot 15 Aug 2021
      RRID:Addgene_44012

      DOI: 10.7554/eLife.66524

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    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  68. Jul 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
    1
    1. scibot 31 Jul 2021
      Plasmid No. 44012

      DOI: 10.1016/j.cell.2021.07.005

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    sciencedirect.com/science/article/pii/S009286742100831X
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
    1
    1. scibot 31 Jul 2021
      plasmid_44012

      DOI: 10.1016/j.celrep.2019.02.054

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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
  71. www.sciencedirect.com www.sciencedirect.com
    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
    1
    1. scibot 29 Jul 2021
      Addgene44012

      DOI: 10.1016/j.ccell.2019.08.006

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    sciencedirect.com/science/article/pii/S1535610819303745
  72. Jun 2021
  73. www.sciencedirect.com www.sciencedirect.com
    NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
    1
    1. scibot 30 Jun 2021
      plasmid_44012

      DOI: 10.1016/j.chembiol.2021.06.001

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    sciencedirect.com/science/article/pii/S2451945621002683
  74. www.sciencedirect.com www.sciencedirect.com
    NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
    1
    1. scibot 17 Jun 2021
      44012

      DOI: 10.1016/j.celrep.2021.109238

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    sciencedirect.com/science/article/pii/S2211124721005970
  75. Apr 2021
  76. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
    1
    1. scibot 29 Apr 2021
      Addgene_44012

      DOI: 10.1016/j.cmet.2020.10.005

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    sciencedirect.com/science/article/pii/S1550413120305386
  77. www.sciencedirect.com www.sciencedirect.com
    Coordinate regulation of the senescent state by selective autophagy
    1
    1. scibot 29 Apr 2021
      Plasmid_44012

      DOI: 10.1016/j.devcel.2021.04.008

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    sciencedirect.com/science/article/pii/S1534580721003178
  78. Mar 2021
  79. journals.plos.org journals.plos.org
    Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks
    1
    1. scibot 30 Mar 2021
      RRID:Addgene_44012

      DOI: 10.1371/journal.ppat.1009460

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    journals.plos.org/plospathogens/article
  80. www.sciencedirect.com www.sciencedirect.com
    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
    1
    1. scibot 01 Mar 2021
      Plasmid_44012

      DOI: 10.1016/j.cell.2020.12.031

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    sciencedirect.com/science/article/pii/S0092867420317530
  81. Feb 2021
  82. www.sciencedirect.com www.sciencedirect.com
    CARM1 regulates replication fork speed and stress response by stimulating PARP1
    1
    1. scibot 28 Feb 2021
      plasmid_44012

      DOI: 10.1016/j.molcel.2020.12.010

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    sciencedirect.com/science/article/pii/S1097276520309023
  83. Jan 2021
  84. www.sciencedirect.com www.sciencedirect.com
    A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
    1
    1. scibot 27 Jan 2021
      RRID:Addgene_44012

      DOI: 10.1016/j.celrep.2020.108675

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    sciencedirect.com/science/article/pii/S2211124720316648
  85. www.sciencedirect.com www.sciencedirect.com
    Increased demand for NAD+ relative to ATP drives aerobic glycolysis
    1
    1. scibot 05 Jan 2021
      RRID:Addgene_44012

      DOI: 10.1016/j.molcel.2020.12.012

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    sciencedirect.com/science/article/pii/S1097276520309047
  86. Dec 2020
  87. www.sciencedirect.com www.sciencedirect.com
    Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
    1
    1. scibot 07 Dec 2020
      RRID:Addgene_44012

      DOI: 10.1016/j.celrep.2020.108444

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    sciencedirect.com/science/article/pii/S2211124720314339
  88. Sep 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_44012

      DOI: 10.1016/j.ccell.2020.04.002

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    sciencedirect.com/science/article/pii/S1535610820301641
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response
    1
    1. scibot 05 Sep 2020
      plasmid_44012

      DOI: 10.18632/oncotarget.27458

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    ncbi.nlm.nih.gov/pmc/articles/PMC7007297/
  91. Jan 2020
  92. elifesciences.org elifesciences.org
    Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport
    1
    1. scibot 13 Jan 2020
      plasmid_44012

      DOI: 10.7554/eLife.44752

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    elifesciences.org/articles/44752
  93. www.sciencedirect.com www.sciencedirect.com
    Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_44012

      DOI: 10.1016/j.cub.2019.07.021

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    sciencedirect.com/science/article/pii/S0960982219308668
  94. www.sciencedirect.com www.sciencedirect.com
    MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_44012

      DOI: 10.1016/j.molcel.2019.09.011

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    sciencedirect.com/science/article/pii/S1097276519306963
  95. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      plasmid_44012

      DOI: 10.1016/j.molcel.2019.01.004

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    sciencedirect.com/science/article/pii/S1097276519300048
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
    1
    1. scibot 13 Jan 2020
      plasmid_44012

      DOI: 10.1016/j.celrep.2019.02.054

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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/