50 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
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    pmc.ncbi.nlm.nih.gov/articles/PMC12863257/
  3. Aug 2026
  4. www.biorxiv.org www.biorxiv.org
    Integrating functional genomics and proteomics identifies Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in T-cell lymphoma
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    biorxiv.org/content/10.1101/2025.10.08.681217v1
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional genomics and proteomics identify Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in diverse T-cell lymphoma models
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    pmc.ncbi.nlm.nih.gov/articles/PMC13432065/
  6. Feb 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping kinase-dependent tumor immune adaptation with multiplexed single-cell CRISPR screens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12803220/
  8. Dec 2025
  9. 54.241.53.176 54.241.53.176
    2025.12.02.691925.full-html.html
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    54.241.53.176/cd1b7ae1b6e0f6a28fee1f41b647536d452cfc4e/2025.12.02.691925.full-html.html
  10. Nov 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
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    pmc.ncbi.nlm.nih.gov/articles/PMC12611757/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12423289/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for simplified parallel perturbations using an abridged long non-coding RNA CRISPR library
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509891/
  14. Aug 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11949624/
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236722/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12198384/
  19. May 2025
  20. www.sciencedirect.com www.sciencedirect.com
    Two waves of adipogenesis in developing avian skin and dermal plasticity
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    sciencedirect.com/science/article/pii/S0012160625001423
  21. Apr 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11937597/
  23. Mar 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Two unrelated distal genes activated by a shared enhancer benefit from localizing inside the same small topological domain
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    pmc.ncbi.nlm.nih.gov/articles/PMC11874980/
  25. Feb 2025
  26. www.sciencedirect.com www.sciencedirect.com
    Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations
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    sciencedirect.com/science/article/pii/S2666979X25000345
  27. link.springer.com link.springer.com
    Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation
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    link.springer.com/article/10.1038/s41388-025-03309-z
  28. Dec 2024
  29. 52.53.155.43 52.53.155.43
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
  32. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  33. Sep 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398463/
  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel reporter for helicase activity in translation uncovers DDX3X interactions
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    ncbi.nlm.nih.gov/pmc/articles/PMC11251518/
  38. Jun 2024
  39. journals.plos.org journals.plos.org
    CRISPRi screen of long non-coding RNAs identifies LINC03045 regulating glioblastoma invasion
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    journals.plos.org/plosgenetics/article
  40. May 2024
  41. www.biorxiv.org www.biorxiv.org
    Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation
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    biorxiv.org/content/10.1101/2024.02.29.582681v1
  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving prime editing with an endogenous small RNA-binding protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
  44. www.sciencedirect.com www.sciencedirect.com
    DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability
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    sciencedirect.com/science/article/pii/S1097276524001886
  45. Mar 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  47. Feb 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879025/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aneuploid embryonic stem cells drive teratoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844504/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794123/
  51. Jan 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large tandem duplications in cancer result from transcription and DNA replication collisions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802642/
  53. Oct 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    sciencedirect.com/science/article/pii/S1934590923003284
  55. www.biorxiv.org www.biorxiv.org
    Determinants of DDX3X sensitivity uncovered using a helicase activity in translation reporter
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    biorxiv.org/content/10.1101/2023.09.14.557805v1
  56. Mar 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
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    sciencedirect.com/science/article/pii/S0960982223002002
  58. Jan 2023
  59. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
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    pubmed.ncbi.nlm.nih.gov/36576240/
  60. Nov 2022
  61. aacrjournals.org aacrjournals.org
    Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2
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    aacrjournals.org/cancerres/article/82/21/3950/709947/Resistance-to-ATR-Inhibitors-Is-Mediated-by-Loss
  62. Feb 2022
  63. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
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    sciencedirect.com/science/article/pii/S1097276522000570
  64. Oct 2021
  65. www.sciencedirect.com www.sciencedirect.com
    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    sciencedirect.com/science/article/pii/S1534580721008054
  66. May 2021
  67. www.embopress.org www.embopress.org
    A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression
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    embopress.org/doi/abs/10.15252/embj.2020106696
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vivo CRISPR screening for novel noncoding RNA functional targets in glioblastoma models
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24850
  69. www.sciencedirect.com www.sciencedirect.com
    Histone methyltransferase activity programs nuclear peripheral genome positioning
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    sciencedirect.com/science/article/pii/S0012160620302062
  70. www.sciencedirect.com www.sciencedirect.com
    Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway
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    sciencedirect.com/science/article/pii/S0960982220310848
  71. Apr 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
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    sciencedirect.com/science/article/pii/S2405471220302945
  73. www.sciencedirect.com www.sciencedirect.com
    B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells
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    sciencedirect.com/science/article/pii/S0092867421001653
  74. Dec 2020
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains
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    ncbi.nlm.nih.gov/pmc/articles/PMC7713251/
  76. Jan 2020
  77. www.sciencedirect.com www.sciencedirect.com
    CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
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    sciencedirect.com/science/article/pii/S0896627319306403
  78. elifesciences.org elifesciences.org
    PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
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    elifesciences.org/articles/48625
  79. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
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    sciencedirect.com/science/article/pii/S1535610819304854