1,124 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reassessment of the roles of coronin proteins as actin effectors and in signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13485075/
  3. www.biorxiv.org www.biorxiv.org
    Engineered endothelial cell grafts form functional anastomoses and enable recruitment of intravenously delivered human T cells in CAM tumor models
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    biorxiv.org/content/10.64898/2026.07.17.739058v1
  4. Aug 2026
  5. aacrjournals.org aacrjournals.org
    Rapid Transcription Dynamics Confers Cytarabine Resistance in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/7/4/624/786176/Rapid-Transcription-Dynamics-Confers-Cytarabine
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70428
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite
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    pmc.ncbi.nlm.nih.gov/articles/PMC13391416/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/Cas9-Engineered HEK293T Cellular Model Harboring the Pathogenic CDKL5 c.172A>T Variant Recapitulates Core Molecular Phenotypes of CDKL5 Deficiency Disorder
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    pmc.ncbi.nlm.nih.gov/articles/PMC13389376/
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    A Quartet of Native Orai Channel Isoforms Orchestrates Graded NFAT Activation and Transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404903/
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    TASP1-mediated cleavage of REV3L enhances the activity of DNA polymerase ζ in mammalian cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13408197/
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    TMEM63B regulates nucleocytoplasmic transport and placental development
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    pmc.ncbi.nlm.nih.gov/articles/PMC13396397/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loop extrusion by cohesin plays a role in enhancer-activated gene expression early in differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402345/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of TGM2 enhances cisplatin sensitivity in MSH2-deficient bladder cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402307/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Analysis of 14q12 microdeletions reveals novel regulatory loci for the neurodevelopmental disorder-related gene FOXG1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392037/
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    Acetylated mitochondrial MDH2 regulates CTR2 transcription to induce cuproptosis during Escherichia coli infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402674/
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    FN1 Knockout Inhibits Tumorigenesis but Promotes Lung Metastasis in Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13439100/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genotoxic antibody-drug conjugates combined with BCL-XL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430021/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An adaptor for feedback regulation of heme biosynthesis by a mitochondrial protease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13425942/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual regulation of the unfolded protein response by IGF2BP3 during ER stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC13431160/
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    M1-linked ubiquitination by LUBAC regulates AMPK signalling and the response to energetic stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC13434424/
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    The anti-tumour activity of TNF in melanoma is determined by cFLIP
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    pmc.ncbi.nlm.nih.gov/articles/PMC13428747/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Magnetic Reprogramming of Macrophages Stimulates Phagocytosis of Breast Cancer Cells via a TRPC1‐STING Inflammatory Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13431815/
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    Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation
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    Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism
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    sciencedirect.com/science/article/pii/S1534580726002753
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    The bile acid-sensive ion channel (BASIC) is expressed in pancreatic α-cells and involved in glucagon secretion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13415342/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Temporal Genomic Analysis of Homogeneous Tumor Models Reveals Key Regulators of Immune Evasion in Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11873729/
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    PUS7 mRNA pseudouridylation is driven by RNA sequence, structure, and cell-type-specific features
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    sciencedirect.com/science/article/pii/S2666979X26001941
  28. Jul 2026
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive mutational characterization of the calcium-sensing STIM1 EF-hand reveals residues essential for structure and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12505291/
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    cPRC1.2 and CTCF-mediated transition from poised to active chromatin loops at bivalent genes
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    link.springer.com/article/10.1038/s44319-026-00885-3
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    SCLC humanized mice identify T cell infiltration phenotypes in response to combination immune-radiation therapies
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    sciencedirect.com/science/article/pii/S258900422602242X
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    The imprinted Peg3 gene is a potent regulator of the DNA methylome in trophoblast cells
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    Structures of dynamic interactors at native proteasomes by PhIX-MS and cryo-electron microscopy
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    sciencedirect.com/science/article/pii/S1097276526004211
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    L-type voltage-gated Ca2+ channels control T cell killing via non-canonical Hedgehog signalling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13354577/
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    TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancer
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    nature.com/articles/s41586-026-10705-2
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARG regulates the proteasomal degradation of TARG1
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    Glycoform engineering of a mammalian platform to sculpt a humanized recombinant bioscavenger
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    sciencedirect.com/science/article/pii/S2405471226001377
  38. Jun 2026
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    CRISPR/Cas9-mediated editing of ERCC6 in iPSCs: A disease model for Cockayne Syndrome type B
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    sciencedirect.com/science/article/pii/S1873506126001406
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13290227/
  41. www.biorxiv.org www.biorxiv.org
    CRISPR-mediated conditional mutagenesis of Smad1/5/8 reveals BMP/GDF signaling restricts postnatal bone overgrowth
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    biorxiv.org/content/10.64898/2026.01.22.701170v1
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13285898/
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    Mitochondrial morphology and function are tuned by microtubule association
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    biorxiv.org/content/10.64898/2026.06.13.731791v1
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    Biallelic rescue of CTG18.1 in two Fuchs endothelial corneal dystrophy–derived iPSC lines (SCTCi047-A-2, SCTCi046-A-2) following a two-step gene editing strategy
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  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing Immunotherapeutic Response in Colorectal Cancer with a Neuropilin-1-Targeting Tumor-Penetrating Peptide
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    pmc.ncbi.nlm.nih.gov/articles/PMC13250810/
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    Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13249207/
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    Baicalin alleviates mastitis in dairy cows by targeting IL-17RA to inhibit IL-17 signaling pathway activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13085363/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Compact Cas12f enables genome editing in avian cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13242000/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRCA1 deficiency induces NFκB-dependent type-I interferon signaling in fallopian tube epithelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13223825/
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    Distinct 2-phenylimidazo[1,2-a]pyridine derivatives that inhibit breast cancer cell proliferation identified as AHR ligands
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    pmc.ncbi.nlm.nih.gov/articles/PMC13197777/
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    WSTF deficiency reprograms regulatory networks by linking locus–specific chromatin remodeling to altered isoform expression and misdirected signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13244151/
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    PAF1C restores transcription after DNA damage independently of promoting histone mark deposition
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    Deletion of mitochondrial calcium uniporter enhances calcium signals by slowing calcium clearance and triggers adaptive transcriptomic remodeling
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    A RiboCancer cell line panel reveals that CLL‐associated Rps15 mutations translationally rewire transcription through codon‐specific tRNA accommodation defects
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    pmc.ncbi.nlm.nih.gov/articles/PMC13239286/
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    CFP1 promotes B cell class switch recombination through the regulation of S region germline transcription and proliferation
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    sciencedirect.com/science/article/pii/S2589004226016305
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endocytosis at the mouse blood brain barrier is elevated during sleep
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  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improvement of chicken genome editing efficiency in vitro using ribonucleoprotein-mediated CRISPR/Cas9 delivery
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    pmc.ncbi.nlm.nih.gov/articles/PMC13137644/
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    LIPT1 loss confers replication stress and PARP inhibitor sensitivity through PrimPol-mediated ssDNA gaps
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  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TCF3::HLF orchestrates an enhancer-promoter network with activation of MEF2C to promote immature HSC gene expression in leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC13148343/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to Sox2 looping with its distal enhancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13224857/
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    Human pluripotent stem cell engineering with CRISPR–Cas9 for Parkinson’s disease
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    The insertion of an ATTTC repeat in an Alu element hyperactivates a neurodevelopmental enhancer in spinocerebellar ataxia type 37
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    pmc.ncbi.nlm.nih.gov/articles/PMC13125401/
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    Orderly mitosis shapes interphase genome architecture
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    The multifaceted role of EXOC6A in ciliogenesis
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    Structural evolution of the MTCH family of mitochondrial insertases
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    Base editing in the AUTS2 gene and high-throughput NGS genotyping of clones: a strategy for generating a cellular model
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    Regulation of the proteasome 20S core particle by the Parkinsonism-associated Proteins FBXO7 and PI31
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    biorxiv.org/content/10.64898/2026.05.28.728263v1
  68. May 2026
  69. www.sciencedirect.com www.sciencedirect.com
    Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes
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    sciencedirect.com/science/article/pii/S1097276526002881
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    Ascl1 promotes OPC specification across species and central nervous system regions and its gliogenic function is regulated by phosphorylation
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    sciencedirect.com/science/article/pii/S0012160626001168
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    Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance
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    sciencedirect.com/science/article/pii/S2589004226013532
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    ISG15 negatively regulates RIPK3-mediated cell death and viral pathogenesis
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    sciencedirect.com/science/article/pii/S2211124726004389
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70266
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of cAMP-mediated lysosomal pH modulation in ATP6V1B2-related neuropathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC13150000/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MLC1 alteration in human iPSCs give rise to disease-like cellular vacuolation phenotype in the astrocyte lineage
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    Generation of an iPSC line IUFi004-A-13 with homozygous NDUFS1 mutation for the study of Leigh syndrome
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    sciencedirect.com/science/article/pii/S187350612600098X
  77. Apr 2026
  78. dx.doi.org dx.doi.org
    FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation
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    dx.doi.org/10.1242/dmm.052634
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108870/
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    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089303/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Accessibility at a primed distal Fshb-Kcna4 super-enhancer is facilitated by Foxl2 during gonadotrope differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13070611/
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    Mechanism of STMN2 cryptic splice/polyadenylation and its correction for TDP-43 proteinopathies
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    pmc.ncbi.nlm.nih.gov/articles/PMC10148063/
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    Shaping Tumor Microenvironment by Amplifying the Complement Cascade for Improved Immune Response in Pancreatic Cancer Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC13060627/
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    Multivalent 28S rRNA expansion segments enable reconstitution of multilayered nucleolar architecture
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    U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13042807/
  87. www.biorxiv.org www.biorxiv.org
    Effects of CTCF on the regulatory landscape of the mouse Sox2 locus
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    biorxiv.org/content/10.64898/2026.03.16.711995v1
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    Reassessment of RNF43 Function Reveals No Impact on Endogenous EGFR or BRAF Protein Stability
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    biorxiv.org/content/10.64898/2026.03.18.712374v1
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    βII and βIII spectrin paralogues define robustness and specialization of the neuronal membrane periodic skeleton
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    biorxiv.org/content/10.64898/2026.03.23.713115v1
  90. Mar 2026
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimizing CRISPR precision in mouse embryos via microhomology-mediated end joining-dominant targeting
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    pmc.ncbi.nlm.nih.gov/articles/PMC13009206/
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    1-s2.0-S2352345X26000494-main-html.html
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