1,059 Matching Annotations
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    Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance
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    sciencedirect.com/science/article/pii/S2589004226013532
  3. May 2026
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    ISG15 negatively regulates RIPK3-mediated cell death and viral pathogenesis
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    sciencedirect.com/science/article/pii/S2211124726004389
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70266
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    Therapeutic potential of cAMP-mediated lysosomal pH modulation in ATP6V1B2-related neuropathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC13150000/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MLC1 alteration in human iPSCs give rise to disease-like cellular vacuolation phenotype in the astrocyte lineage
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    Generation of an iPSC line IUFi004-A-13 with homozygous NDUFS1 mutation for the study of Leigh syndrome
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    sciencedirect.com/science/article/pii/S187350612600098X
  9. Apr 2026
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    FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation
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    dx.doi.org/10.1242/dmm.052634
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    Prion propagation is controlled by a hierarchical network involving the nuclear Tfap2c and hnRNP K factors and the cytosolic mTORC1 complex
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    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    Accessibility at a primed distal Fshb-Kcna4 super-enhancer is facilitated by Foxl2 during gonadotrope differentiation
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    Mechanism of STMN2 cryptic splice/polyadenylation and its correction for TDP-43 proteinopathies
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    Shaping Tumor Microenvironment by Amplifying the Complement Cascade for Improved Immune Response in Pancreatic Cancer Model
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    Multivalent 28S rRNA expansion segments enable reconstitution of multilayered nucleolar architecture
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    U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
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    Effects of CTCF on the regulatory landscape of the mouse Sox2 locus
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    biorxiv.org/content/10.64898/2026.03.16.711995v1
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    Reassessment of RNF43 Function Reveals No Impact on Endogenous EGFR or BRAF Protein Stability
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    βII and βIII spectrin paralogues define robustness and specialization of the neuronal membrane periodic skeleton
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  22. Mar 2026
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimizing CRISPR precision in mouse embryos via microhomology-mediated end joining-dominant targeting
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    A single-cell CRISPR screen defines a gene regulatory network governing human pluripotency in primed and naive cells
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    Recurrent Immunogenic Neoantigens and Their Cognate T-cell Receptors in Treatment-Resistant Metastatic Prostate Cancer
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    CBP-IDRs regulate acetylation and gene expression
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    ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms
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  29. Feb 2026
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity
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    The integrated stress response promotes immune evasion through lipocalin 2
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    Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer
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    Expression of low molecular weight protein tyrosine phosphatase in gastric cancer and its association with clinical outcomes and oncogenic hallmarks
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    Porcine IRF2 suppresses the cGAS-STING-mediated antiviral IFN signaling by competing IRF3 for binding to the IFN promoter
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    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
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    TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
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    The Template-Jumping Editing Approach in F9-Associated Hemophilia B Gene Therapy
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  41. Jan 2026
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    African pygmy mouse iPSCs as a model for in vitro embryogenesis, interspecies chimerism, and blastocyst complementation
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    AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy
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    CRISPR/Cas9-mediated gene editing in trophoblast cells via mechanoporation for preeclampsia insight
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    Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression
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    Identification of new interactors of eIF3f by endogenous proximity-dependent biotin labelling in human muscle cells
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    LncRNA CISTR-ACT regulates cell size in human and mouse by guiding FOSL2
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    Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder
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    Genotype-phenotype mapping identifies fetal-like CD55+ immunoregulatory cancer cells as mediators of immune escape in colorectal cancer
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    Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS
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  52. elifesciences.org elifesciences.org
    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
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    A CLOCK-targeting lncRNA induces trained immunity against tuberculosis
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  54. Dec 2025
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    Generation of a pluripotent human AGK knockout embryonic stem cell model (WAe009-A-3C) of Sengers syndrome
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    Deprivation of EGFR signal causes senolysis in PDAC with CDK4/6 inhibition
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    Doublecortin reinforces microtubules to promote growth cone advance in soft environments
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    A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication
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    A next-generation dual guide CRISPR system for genetic interaction library screening
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    Biallelic excision of the CTG18.1 repeat expansion in two FUCHS endothelial corneal dystrophy-derived iPSC lines and one control (SCTCi046-A-1, SCTCi047-A-1 and SCTCi041-A-1) using an episomal vector-based CRISPR/Cas9 approach
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  61. Nov 2025
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    Chromatin activity of IκBα mediates the exit from naïve pluripotency
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    NRDE2 Interacts with an Early Transcription Elongation Complex and Widely Impacts Gene Expression
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    Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC
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    PD-L1 regulates c-MET phosphorylation and contributes to MET-dependent resistance to osimertinib in EGFR-mutant NSCLC
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    RCC2 and CD24 cooperate to modulate prostate cancer progression through vimentin ubiquitination and β-catenin activation
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    Autophagy disruption primes CAR-T cell metabolism for sustained rejection of ovarian tumors
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    mRNA turnover dynamics are affected by cell differentiation and loss of the cytosine methyltransferase Nsun2
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    Modelling arrhythmogenic cardiomyopathy fattyfibro pathology with PKP2-deficient epicardial cells derived from human iPSCs
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    5-Formylcytosine is not a prevalent RNA modification in mammalian cells
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    A Rho GTPase-effector ensemble governs cell migration behavior
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    Mitotic DNA repair by TMEJ suppresses replication stress-induced nuclear envelope reassembly defect
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    Validating TDP1 as an Inhibition Target for Lipophilic Nucleoside Derivative in Human Cells
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    A porcine model of Fanconi anemia
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    Secretory IgA amplification during immune checkpoint blockade enhances the control of tumor growth by enterotropic T cells
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    LUBAC modulates CBM complex functions downstream of TRAF6 in T cells
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    Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions
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    The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generating a Cell Model to Study ER Stress in iPSC-Derived Medium Spiny Neurons from a Patient with Huntington’s Disease
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    CD46 is a cellular receptor for species D human adenovirus
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  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing macrophage phagocytosis of cancers by disrupting the SIRPα/CD47 signaling axis and targeting MUC1 antigen
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    pmc.ncbi.nlm.nih.gov/articles/PMC12631164/
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    SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601339/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant
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  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Highly stable Cas9 promotes HBV genome destruction by antagonizing HSC70-mediated degradation
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    CETN3 deficiency induces microcephaly by disrupting neural stem/progenitor cell fate through impaired centrosome assembly and RNA splicing
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    The actin nucleation promoting factor WASH facilitates clathrin-independent endocytosis of human papillomaviruses
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    ABCA7 variants impact phosphatidylcholine and mitochondria in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12611789/
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    DNA2 enables growth by restricting recombination-restarted replication
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    RNA-binding proteins mediate the maturation of chromatin topology during differentiation
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    A novel peptide-based strategy to enhance GBA1 expression for treating Parkinson’s disease
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    Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics
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  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  184. 52.53.155.43 52.53.155.43
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  185. Jul 2025
  186. www.biorxiv.org www.biorxiv.org
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  190. www.nature.com www.nature.com
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  191. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  193. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  196. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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