535 Matching Annotations
  1. Mar 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by promoting apoptosis resistance and metabolic dysregulation
    1
    1. scibot 04 Mar 2023
      Plasmid_4813845

      DOI: 10.1038/s42003-023-04611-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977882/
  3. Feb 2023
  4. www.sciencedirect.com www.sciencedirect.com
    EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
    1
    1. scibot 24 Feb 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.neuron.2023.02.001

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    sciencedirect.com/science/article/pii/S089662732300079X
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant
    1
    1. scibot 15 Feb 2023
      Addgene plasmid 48138

      DOI: 10.7554/eLife.84143

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    ncbi.nlm.nih.gov/pmc/articles/PMC9917429/
  6. www.nature.com www.nature.com
    Homology-directed repair of an MYBPC3 gene mutation in a rat model of hypertrophic cardiomyopathy
    1
    1. scibot 11 Feb 2023
      RRID:Addgene_48138

      DOI: 10.1038/s41434-023-00384-3

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    nature.com/articles/s41434-023-00384-3
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity
    1
    1. scibot 10 Feb 2023
      Addgene_48138

      DOI: 10.1158/2159-8290.CD-22-0528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9901536/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells
    1
    1. scibot 08 Feb 2023
      RRID:Addgene_48138

      DOI: 10.3389/fcell.2023.1085913

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    ncbi.nlm.nih.gov/pmc/articles/PMC9895848/
  9. www.sciencedirect.com www.sciencedirect.com
    Generation of two CRISPR/Cas edited human induced pluripotent stem cell lines (DHMi005-A-3 and DHMi005-A-4) carrying a FLAG-tag after exon 9 of the TBX5 gene
    1
    1. scibot 03 Feb 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.scr.2022.103011

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    sciencedirect.com/science/article/pii/S1873506122003609
  10. Jan 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis
    1
    1. scibot 28 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.bbi.2022.12.020

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    sciencedirect.com/science/article/pii/S0889159122004780
  12. www.sciencedirect.com www.sciencedirect.com
    Neutrophil-activating therapy for the treatment of cancer
    1
    1. scibot 27 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.ccell.2023.01.002

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    sciencedirect.com/science/article/pii/S1535610823000028
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAR RNA editing on antisense RNAs results in apparent U-to-C base changes on overlapping sense transcripts
    1
    1. scibot 25 Jan 2023
      RRID:Addgene_48138

      DOI: 10.3389/fcell.2022.1080626

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    ncbi.nlm.nih.gov/pmc/articles/PMC9852825/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification
    1
    1. scibot 20 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1038/s41467-023-35910-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC9845378/
  15. www.sciencedirect.com www.sciencedirect.com
    An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes
    1
    1. scibot 19 Jan 2023
      Plasmid_48138

      DOI: 10.1016/j.cell.2022.12.025

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    sciencedirect.com/science/article/pii/S0092867422015380
  16. www.sciencedirect.com www.sciencedirect.com
    A deep learning platform to assess drug proarrhythmia risk
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.stem.2022.12.002

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    sciencedirect.com/science/article/pii/S1934590922004866
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1126/scitranslmed.abj1270

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812757/
  18. www.sciencedirect.com www.sciencedirect.com
    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.immuni.2022.12.010

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    sciencedirect.com/science/article/pii/S107476132200646X
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential roles of type I interferon signaling in tumor versus host cells in experimental glioma models
    1
    1. scibot 06 Jan 2023
      RRID:Addgene_48138

      DOI: 10.1016/j.tranon.2022.101607

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    ncbi.nlm.nih.gov/pmc/articles/PMC9800198/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Methyltransferase KMT2B Promotes Metastasis and Angiogenesis of Cervical Cancer by Upregulating EGF Expression
    1
    1. scibot 06 Jan 2023
      RRID:Addgene_48138

      DOI: 10.7150/ijbs.72381

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    ncbi.nlm.nih.gov/pmc/articles/PMC9760441/
  21. www.sciencedirect.com www.sciencedirect.com
    ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
    1
    1. scibot 02 Jan 2023
      Addgene_48138

      DOI: 10.1016/j.celrep.2022.111909

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    sciencedirect.com/science/article/pii/S2211124722018083
  22. Dec 2022
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery
    1
    1. scibot 31 Dec 2022
      plasmid_48138

      DOI: 10.1038/s41598-022-25959-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC9758134/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9-mediated LRP10 Knockout in HuTu-80 and HEK 293T Cell Lines
    1
    1. scibot 31 Dec 2022
      RRID:Addgene_48138

      DOI: 10.21769/BioProtoc.4521

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    ncbi.nlm.nih.gov/pmc/articles/PMC9548521/
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between tumor acidosis, p53, and extracellular matrix regulates pancreatic cancer aggressiveness
    1
    1. scibot 22 Dec 2022
      Addgene_48138

      DOI: 10.1002/ijc.34367

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34367
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome Editing Is Induced in a Binary Manner in Single Human Cells
    1
    1. scibot 09 Dec 2022
      plasmid_48138

      DOI: 10.1016/j.isci.2022.105619

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    ncbi.nlm.nih.gov/pmc/articles/PMC9722467/
  27. jitc.bmj.com jitc.bmj.com
    Development of 89Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration
    1
    1. scibot 08 Dec 2022
      RRID:Addgene_48138

      DOI: 10.1136/jitc-2022-004877

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    jitc.bmj.com/content/10/12/e004877
  28. www.sciencedirect.com www.sciencedirect.com
    Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity
    1
    1. scibot 08 Dec 2022
      RRID:Addgene_48138

      DOI: 10.1016/j.celrep.2022.111775

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    sciencedirect.com/science/article/pii/S2211124722016588
  29. Nov 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
    1
    1. scibot 24 Nov 2022
      Addgene_48138

      DOI: 10.1016/j.celrep.2022.111678

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    sciencedirect.com/science/article/pii/S2211124722015522
  31. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
    1
    1. scibot 22 Nov 2022
      48138

      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP10 Mediates Mono-ADP-Ribosylation of Aurora-A Regulating G2/M Transition of the Cell Cycle
    1
    1. scibot 18 Nov 2022
      plasmid_48138

      DOI: 10.3390/cancers14215210

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    ncbi.nlm.nih.gov/pmc/articles/PMC9659153/
  33. www.molbiolcell.org www.molbiolcell.org
    Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1
    1
    1. scibot 17 Nov 2022
      plasmid_48138

      DOI: 10.1091/mbc.E21-12-0603

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    molbiolcell.org/doi/10.1091/mbc.E21-12-0603
  34. www.researchsquare.com www.researchsquare.com
    Home
    1
    1. scibot 11 Nov 2022
      plasmid_48138

      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/
  35. www.sciencedirect.com www.sciencedirect.com
    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
    1
    1. scibot 05 Nov 2022
      plasmid_48138

      DOI: 10.1016/j.celrep.2022.111489

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    sciencedirect.com/science/article/pii/S2211124722013390
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Docking of Syk to FcεRI is enhanced by Lyn but limited in duration by SHIP1
    1
    1. scibot 04 Nov 2022
      plasmid_48138

      DOI: 10.1091/mbc.E21-12-0603

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    ncbi.nlm.nih.gov/pmc/articles/PMC9582627/
  37. Oct 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
    1
    1. scibot 20 Oct 2022
      plasmid_48138

      DOI: 10.1016/j.celrep.2022.111514

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    sciencedirect.com/science/article/pii/S221112472201364X
  39. academic.oup.com academic.oup.com
    Two type I topoisomerases maintain DNA topology in human mitochondria
    1
    1. scibot 15 Oct 2022
      RRID:Addgene_48138

      DOI: 10.1093/nar/gkac857

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac857/6754920
  40. www.sciencedirect.com www.sciencedirect.com
    Generation of a human embryonic stem cell line targeted homozygous deletion of BMP10 (WAe007-A-2) by CRISPR/Cas9-dgRNA
    1
    1. scibot 14 Oct 2022
      Addgene_48138

      DOI: 10.1016/j.scr.2022.102942

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    sciencedirect.com/science/article/pii/S1873506122002914
  41. www.nature.com www.nature.com
    Caldesmon controls stress fiber force-balance through dynamic cross-linking of myosin II and actin-tropomyosin filaments
    1
    1. scibot 14 Oct 2022
      plasmid_48138

      DOI: 10.1038/s41467-022-33688-w

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    nature.com/articles/s41467-022-33688-w
  42. www.sciencedirect.com www.sciencedirect.com
    Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex
    1
    1. scibot 12 Oct 2022
      Addgene_48138

      DOI: 10.1016/j.celrep.2022.111483

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    sciencedirect.com/science/article/pii/S221112472201333X
  43. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
    1
    1. scibot 07 Oct 2022
      Cat#48138

      DOI: 10.1016/j.molcel.2022.09.007

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    sciencedirect.com/science/article/pii/S1097276522008966
  44. www.sciencedirect.com www.sciencedirect.com
    Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
    1
    1. scibot 05 Oct 2022
      Addgene_48138

      DOI: 10.1016/j.cmet.2022.09.005

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    sciencedirect.com/science/article/pii/S1550413122003953
  45. Sep 2022
  46. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
    1
    1. scibot 29 Sep 2022
      plasmid_48138

      DOI: 10.15252/embr.202154136

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    embopress.org/doi/10.15252/embr.202154136
  47. www.sciencedirect.com www.sciencedirect.com
    Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome
    1
    1. scibot 27 Sep 2022
      plasmid_48138

      DOI: 10.1016/j.cels.2022.09.001

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    sciencedirect.com/science/article/pii/S2405471222003532
  48. www.sciencedirect.com www.sciencedirect.com
    Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu5a receptor internalization
    1
    1. scibot 14 Sep 2022
      RRID:Addgene_48138

      DOI: 10.1016/j.jbc.2022.102466

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    sciencedirect.com/science/article/pii/S0021925822009097
  49. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
    1
    1. scibot 03 Sep 2022
      Addgene 48138

      DOI: 10.1016/j.cell.2022.07.025

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    sciencedirect.com/science/article/pii/S0092867422009783
  50. Aug 2022
  51. 52.53.155.43 52.53.155.43
    mcr-21-0058-html.html
    1
    1. scibot 27 Aug 2022
      RRID:Addgene_48138

      DOI: 10.1158/1541-7786.MCR-21-0058

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  52. www.sciencedirect.com www.sciencedirect.com
    SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
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  53. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal
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  56. www.nature.com www.nature.com
    A multimodal iPSC platform for cystic fibrosis drug testing
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  57. Jul 2022
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    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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    “Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes
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    The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
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  61. Jun 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
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  63. elifesciences.org elifesciences.org
    GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
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    Interplay between symmetric arginine dimethylation and ubiquitylation regulates TDP1 proteostasis for the repair of topoisomerase I-DNA adducts
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  65. rupress.org rupress.org
    ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
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  66. www.sciencedirect.com www.sciencedirect.com
    A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells
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  67. May 2022
  68. www.nature.com www.nature.com
    Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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  70. www.mdpi.com www.mdpi.com
    First Characterization of Human Dermal Fibroblasts Showing a Decreased Xylosyltransferase-I Expression Induced by the CRISPR/Cas9 System
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  71. www.sciencedirect.com www.sciencedirect.com
    Generation of a MIR5004 knockout cell line from human induced Pluripotent Stem Cells by CRISPR/Cas9 gene editing
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    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
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  73. Apr 2022
  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance
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  75. academic.oup.com academic.oup.com
    A rationalized definition of general tumor suppressor microRNAs excludes miR-34a
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac277/6574673
  76. www.sciencedirect.com www.sciencedirect.com
    The cargo adaptor protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection
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  77. www.sciencedirect.com www.sciencedirect.com
    RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development
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  78. www.biorxiv.org www.biorxiv.org
    ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by driving the Warburg effect and apoptosis resistance
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiation
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway
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  81. Mar 2022
  82. www.sciencedirect.com www.sciencedirect.com
    Genome-wide analysis of haploinsufficiency in human embryonic stem cells
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    Rif1 and Hmgn3 regulate the conversion of murine trophoblast stem cells
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    Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9-mediated induction of large chromosomal inversions in human bronchial epithelial cells
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insights From Long-term Follow-up of a Girl With Adrenal Insufficiency and Sphingosine-1-Phosphate Lyase Deficiency
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The m6A(m)-independent role of FTO in regulating WNT signaling pathways
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  90. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity
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  92. www.nature.com www.nature.com
    Rap1 prevents colitogenic Th17 cell expansion and facilitates Treg cell differentiation and distal TCR signaling
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ciliopathy complex builds distal appendages to initiate ciliogenesis
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  94. www.sciencedirect.com www.sciencedirect.com
    A simple protocol to isolate a single human cell PRDX1 knockout generated by CRISPR-Cas9 system
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    sciencedirect.com/science/article/pii/S266616672200096X
  95. www.sciencedirect.com www.sciencedirect.com
    Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma
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  96. www.sciencedirect.com www.sciencedirect.com
    Diacylglycerol kinase η regulates cell proliferation and its levels are elevated by glucocorticoids in undifferentiated neuroblastoma cells
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  97. www.sciencedirect.com www.sciencedirect.com
    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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      plasmid_48138

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  98. www.sciencedirect.com www.sciencedirect.com
    BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states
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  99. Feb 2022
  100. www.sciencedirect.com www.sciencedirect.com
    Gene architecture directs splicing outcome in separate nuclear spatial regions
    1
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      DOI: 10.1016/j.molcel.2022.02.001

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  101. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
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  102. www.nature.com www.nature.com
    The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner
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      DOI: 10.1038/s41388-021-02161-1

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    nature.com/articles/s41388-021-02161-1
  103. Jan 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation
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      DOI: 10.1007/s12031-021-01943-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC8763444/
  105. link.springer.com link.springer.com
    Plasmolipin regulates basolateral-to-apical transcytosis of ICAM-1 and leukocyte adhesion in polarized hepatic epithelial cells
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      DOI: 10.1007/s00018-021-04095-z

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  106. www.sciencedirect.com www.sciencedirect.com
    Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA
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    sciencedirect.com/science/article/pii/S2211124721017009
  107. www.mdpi.com www.mdpi.com
    Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells
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      DOI: 10.3390/vaccines9121446

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  108. Dec 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Dichotomous Effects of Cellular Expression of STAT3 on Tumor Growth of HNSCC
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  110. www.mdpi.com www.mdpi.com
    Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells
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  111. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
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    link.springer.com/article/10.1186/s40170-021-00277-2
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel live-cell imaging assay reveals regulation of endosome maturation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8635980/
  113. www.sciencedirect.com www.sciencedirect.com
    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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  114. www.sciencedirect.com www.sciencedirect.com
    Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops
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  115. academic.oup.com academic.oup.com
    Evidence for nutrient-dependent regulation of the COPII coat by O-GlcNAcylation
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      plasmid_48138

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    academic.oup.com/glycob/article/31/9/1102/6299516
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic Analysis of 4E-BP1 Phosphorylation in Neurons with Tsc2 or Depdc5 Knockout
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    1. scibot 02 Dec 2021
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      DOI: 10.1016/j.expneurol.2020.113432

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    ncbi.nlm.nih.gov/pmc/articles/PMC8170708/
  117. academic.oup.com academic.oup.com
    Detection of Neanderthal Adaptively Introgressed Genetic Variants that Modulate Reporter Gene Expression in Human Immune Cells
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      DOI: 10.1093/molbev/msab304

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    academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msab304/6400258
  118. Nov 2021
  119. www.sciencedirect.com www.sciencedirect.com
    Generation of auxin inducible degron (AID) knock-in cell lines for targeted protein degradation in mammalian cells
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      Addgene_48138

      DOI: 10.1016/j.xpro.2021.100949

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    sciencedirect.com/science/article/pii/S2666166721006559
  120. www.sciencedirect.com www.sciencedirect.com
    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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      RRID:Addgene_48138

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    sciencedirect.com/science/article/pii/S1097276521009096
  121. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13115
  122. www.sciencedirect.com www.sciencedirect.com
    Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
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    1. scibot 17 Nov 2021
      Addgene_48138

      DOI: 10.1016/j.celrep.2021.109994

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    sciencedirect.com/science/article/pii/S221112472101473X
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
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    1. scibot 15 Nov 2021
      RRID:Addgene_48138

      DOI: 10.3390/ijms222111336

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    ncbi.nlm.nih.gov/pmc/articles/PMC8583042/
  124. www.sciencedirect.com www.sciencedirect.com
    Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes
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      Cat# 48138

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    sciencedirect.com/science/article/pii/S2211124721014376
  125. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    1. scibot 10 Nov 2021
      plasmid_48138

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    sciencedirect.com/science/article/pii/S2211124721014686
  126. link.springer.com link.springer.com
    Loss of SORCS2 is Associated with Neuronal DNA Double-Strand Breaks
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    1. scibot 09 Nov 2021
      RRID:Addgene_48138

      DOI: 10.1007/s10571-021-01163-7

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    link.springer.com/article/10.1007/s10571-021-01163-7
  127. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site
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      Addgene Cat # 48138

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    sciencedirect.com/science/article/pii/S0969212621003750
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
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    1. scibot 05 Nov 2021
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      DOI: 10.7554/eLife.65759

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    ncbi.nlm.nih.gov/pmc/articles/PMC8550759/
  129. Oct 2021
  130. www.sciencedirect.com www.sciencedirect.com
    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    1. scibot 28 Oct 2021
      Plasmid_48138

      DOI: 10.1016/j.devcel.2021.10.004

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    sciencedirect.com/science/article/pii/S1534580721008054
  131. www.sciencedirect.com www.sciencedirect.com
    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    1. scibot 21 Oct 2021
      Cat. No. 48138

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    sciencedirect.com/science/article/pii/S2211124721013371
  132. www.sciencedirect.com www.sciencedirect.com
    Syndromic RNA Polymerase II insufficiency: Generation of a human induced pluripotent stem cell line (UUIGPi002A-5) with a heterozygous disruption of POLR2A
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      plasmid_48138

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    sciencedirect.com/science/article/pii/S1873506121004244
  133. www.sciencedirect.com www.sciencedirect.com
    Generation of a homozygous CIITA knockout iPS cell line using the CRISPR-Cas9 system
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    sciencedirect.com/science/article/pii/S187350612100427X
  134. www.sciencedirect.com www.sciencedirect.com
    NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain
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      plasmid_48138

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    sciencedirect.com/science/article/pii/S1097276521007541
  135. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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    sciencedirect.com/science/article/pii/S1097276521007504
  136. Sep 2021
  137. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons
    1
    1. scibot 30 Sep 2021
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      DOI: 10.1111/jnc.15502

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15502
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A mouse model of brittle cornea syndrome caused by mutation in Zfp469
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      RRID:Addgene_48138

      DOI: 10.1242/dmm.049175

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    ncbi.nlm.nih.gov/pmc/articles/PMC8476817/
  139. link.springer.com link.springer.com
    Loss of cancer cell STAT1 improves response to radiation therapy and promotes T cell activation in head and neck squamous cell carcinoma
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      RRID:Addgene_48138

      DOI: 10.1007/s00262-021-03059-3

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  140. www.sciencedirect.com www.sciencedirect.com
    MultiEditR: The first tool for detection and quantification of multiple RNA editing sites from Sanger sequencing demonstrates comparable fidelity to RNA-seq
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      DOI: 10.1016/j.omtn.2021.07.008

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    sciencedirect.com/science/article/pii/S2162253121001761
  141. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line
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      RRID:Addgene_48138

      DOI: 10.1371/journal.pone.0257473

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  143. www.sciencedirect.com www.sciencedirect.com
    RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
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      48138

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    sciencedirect.com/science/article/pii/S193459092100343X
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt target enhancer regulation by a CDX/TCF transcription factor collective and a novel DNA motif
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    1. scibot 14 Sep 2021
      plasmid_48138

      DOI: 10.1093/nar/gkab657

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    ncbi.nlm.nih.gov/pmc/articles/PMC8421206/
  145. Aug 2021
  146. www.sciencedirect.com www.sciencedirect.com
    Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination
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    1. scibot 27 Aug 2021
      RRID:Addgene_48138

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  147. www.sciencedirect.com www.sciencedirect.com
    Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
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      RRID:Addgene_48138

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction
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    Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
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    Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
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    The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of GLA-Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy
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  158. europepmc.org europepmc.org
    In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
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  159. www.sciencedirect.com www.sciencedirect.com
    A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family
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    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
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  163. www.sciencedirect.com www.sciencedirect.com
    Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
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  165. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
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    cell.com/cell-host-microbe/abstract/S1931-3128(17)30245-7
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    The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation
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  168. www.sciencedirect.com www.sciencedirect.com
    Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  170. www.jneurosci.org www.jneurosci.org
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  171. www.sciencedirect.com www.sciencedirect.com
    Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  174. elifesciences.org elifesciences.org
    Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels
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  175. www.sciencedirect.com www.sciencedirect.com
    CRISPR-READI: Efficient Generation of Knockin Mice by CRISPR RNP Electroporation and AAV Donor Infection
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  176. Jul 2021
  177. www.sciencedirect.com www.sciencedirect.com
    The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression
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  178. journals.plos.org journals.plos.org
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    Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons
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    Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Are Small Nucleolar RNAs “CRISPRable”? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells
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  186. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
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    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
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  188. link.springer.com link.springer.com
    Restore natural fertility of <Emphasis Type="Italic">Kit</Emphasis><Superscript><Emphasis Type="Italic">w</Emphasis></Superscript><Emphasis Type="Italic">/Kit</Emphasis><Superscript><Emphasis Type="Italic">wv</Emphasis></Superscript> mouse with nonobstructive azoospermia through gene editing on SSCs mediated by CRISPR-Cas9
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    A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers
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  190. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus
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      plasmid_48138

      DOI: 10.1016/j.celrep.2018.10.052

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    ncbi.nlm.nih.gov/pmc/articles/PMC6287930/
  192. www.sciencedirect.com www.sciencedirect.com
    A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity
    1
    1. scibot 27 Jul 2021
      48138

      DOI: 10.1016/j.celrep.2018.10.088

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    sciencedirect.com/science/article/pii/S2211124718316929
  193. www.cell.com www.cell.com
    Transcription-mediated supercoiling regulates genome folding and loop formation
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    1. scibot 23 Jul 2021
      RRID:Addgene_48138

      DOI: 10.1016/j.molcel.2021.06.009

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00456-1
  194. www.sciencedirect.com www.sciencedirect.com
    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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    1. scibot 09 Jul 2021
      Addgene_48138

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    sciencedirect.com/science/article/pii/S1097276521004962
  195. www.mdpi.com www.mdpi.com
    New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition
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    1. scibot 09 Jul 2021
      RRID:Addgene_48138

      DOI: 10.3390/biom11070973

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    mdpi.com/2218-273X/11/7/973
  196. www.sciencedirect.com www.sciencedirect.com
    The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression
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    1. scibot 09 Jul 2021
      plasmid_48138

      DOI: 10.1016/j.cub.2021.06.030

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    sciencedirect.com/science/article/pii/S0960982221008253
  197. elifesciences.org elifesciences.org
    BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
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    1. scibot 01 Jul 2021
      RRID:Addgene_48138

      DOI: 10.7554/eLife.63254

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    elifesciences.org/articles/63254
  198. www.sciencedirect.com www.sciencedirect.com
    Derivation of induced pluripotent stem cells line (RCPCMi007-A-1) with inactivation of the beta-2-microblogulin gene by CRISPR/Cas9 genome editing
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    1. scibot 01 Jul 2021
      RRID:Addgene_48138

      DOI: 10.1016/j.scr.2021.102451

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    sciencedirect.com/science/article/pii/S1873506121002981
  199. Jun 2021
  200. www.sciencedirect.com www.sciencedirect.com
    Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome
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    1. scibot 30 Jun 2021
      Addgene_48138

      DOI: 10.1016/j.celrep.2021.109321

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    sciencedirect.com/science/article/pii/S2211124721006975
  201. www.sciencedirect.com www.sciencedirect.com
    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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    1. scibot 30 Jun 2021
      plasmid_48138

      DOI: 10.1016/j.molcel.2021.06.020

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    sciencedirect.com/science/article/pii/S1097276521005001
  202. www.embopress.org www.embopress.org
    Cysteamine–bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis
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    1. scibot 26 Jun 2021
      Addgene_48138

      DOI: 10.15252/emmm.202013067

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    embopress.org/doi/full/10.15252/emmm.202013067
  203. link.springer.com link.springer.com
    Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs
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    1. scibot 26 Jun 2021
      RRID:Addgene_48138

      DOI: 10.1007/s40487-021-00158-0

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    link.springer.com/article/10.1007/s40487-021-00158-0
  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HNRNP A1 Promotes Lung Cancer Cell Proliferation by Modulating VRK1 Translation
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    1. scibot 17 Jun 2021
      RRID:Addgene_48138

      DOI: 10.3390/ijms22115506

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    ncbi.nlm.nih.gov/pmc/articles/PMC8197126/
  205. www.cell.com www.cell.com
    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
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    1. scibot 15 Jun 2021
      RRID:Addgene_48138

      DOI: 10.1016/j.ccell.2021.05.007

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    cell.com/cancer-cell/fulltext/S1535-6108(21)00273-7
  206. www.sciencedirect.com www.sciencedirect.com
    A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription
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    1. scibot 12 Jun 2021
      RRID:Addgene_48138

      DOI: 10.1016/j.jbc.2021.100862

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    sciencedirect.com/science/article/pii/S0021925821006621
  207. elifesciences.org elifesciences.org
    Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
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    1. scibot 11 Jun 2021
      RRID:Addgene_48138

      DOI: 10.7554/eLife.59791

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    elifesciences.org/articles/59791
  208. elifesciences.org elifesciences.org
    Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations
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    1. scibot 05 Jun 2021
      RRID :Addgene_48138

      DOI: 10.7554/eLife.67622

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    elifesciences.org/articles/67622
  209. elifesciences.org elifesciences.org
    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
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    1. scibot 05 Jun 2021
      Addgene_48138

      DOI: 10.7554/eLife.68263

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    elifesciences.org/articles/68263
  210. www.sciencedirect.com www.sciencedirect.com
    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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    1. scibot 02 Jun 2021
      Plasmid_48138

      DOI: 10.1016/j.molcel.2021.05.005

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    sciencedirect.com/science/article/pii/S1097276521003622
  211. May 2021
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
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    1. scibot 27 May 2021
      Addgene_48138

      DOI: 10.7554/eLife.64930

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    ncbi.nlm.nih.gov/pmc/articles/PMC8139829/
  213. www.sciencedirect.com www.sciencedirect.com
    Adhesion-mediated mechanosignaling forces mitohormesis
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    1. scibot 21 May 2021
      Addgene_48138

      DOI: 10.1016/j.cmet.2021.04.017

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    sciencedirect.com/science/article/pii/S1550413121001832
  214. www.sciencedirect.com www.sciencedirect.com
    Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways
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    1. scibot 19 May 2021
      plasmid_48138

      DOI: 10.1016/j.celrep.2021.109136

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    sciencedirect.com/science/article/pii/S2211124721004757
  215. link.springer.com link.springer.com
    An Intronic Variant of CHD7 Identified in Autism Patients Interferes with Neuronal Differentiation and Development
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    1. scibot 12 May 2021
      Addgene_48138

      DOI: 10.1007/s12264-021-00685-w

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    link.springer.com/article/10.1007/s12264-021-00685-w
  216. www.sciencedirect.com www.sciencedirect.com
    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
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    1. scibot 12 May 2021
      RRID:Addgene_48138

      DOI: 10.1016/j.celrep.2021.109101

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    sciencedirect.com/science/article/pii/S2211124721004356
  217. www.nature.com www.nature.com
    Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler
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    1. scibot 10 May 2021
      RRID:Addgene_48138

      DOI: 10.1038/s41388-021-01804-7

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    nature.com/articles/s41388-021-01804-7
  218. www.sciencedirect.com www.sciencedirect.com
    ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
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    1. scibot 08 May 2021
      plasmid_48138

      DOI: 10.1016/j.molcel.2021.03.001

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    sciencedirect.com/science/article/pii/S1097276521001696
  219. www.sciencedirect.com www.sciencedirect.com
    Paradoxical Mitophagy Regulation by PINK1 and TUFm
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    1. scibot 07 May 2021
      Addgene_48138

      DOI: 10.1016/j.molcel.2020.10.007

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    sciencedirect.com/science/article/pii/S1097276520306900
  220. www.sciencedirect.com www.sciencedirect.com
    GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control
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    1. scibot 07 May 2021
      plasmid_48138

      DOI: 10.1016/j.molcel.2020.07.007

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    sciencedirect.com/science/article/pii/S1097276520304731
  221. www.sciencedirect.com www.sciencedirect.com
    ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
    1
    1. scibot 07 May 2021
      Plasmid_48138

      DOI: 10.1016/j.molcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1097276520303026
  222. www.sciencedirect.com www.sciencedirect.com
    SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt
    1
    1. scibot 06 May 2021
      Addgene_48138

      DOI: 10.1016/j.devcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1534580721002069